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Pediatric Gastrointestinal and Liver Disease. Edition No. 6

  • Book

  • December 2020
  • Elsevier Health Science
  • ID: 5018910
Now with full-color illustrations throughout, dozens of new review questions, and state-of-the-art coverage of this fast-changing area, Pediatric Gastrointestinal and Liver Disease, 6th Edition, remains the leading text in the field. You'll find definitive guidance on diagnosis and treatment from experienced editors Drs. Robert Wyllie, Jeffrey S. Hyams, and Marsha Kay, as well as globally renowned contributors who share their knowledge and expertise on complex issues.

- Features an enhanced art program with full-color anatomical figures, clinical photos, and other illustrations throughout the text.

- Includes a new chapter on fecal transplantation (FCT), covering donor and recipient screening, preparation, delivery, follow-up, and safety considerations, as well as investigative uses for FCT for disorders such as IBD, IBS, and D-lactic acidosis.

- Prepares you for certification and recertification with more than 400 board review-style questions, answers, and rationales - 30% new to this edition.

- Includes detailed diagrams that accurately illustrate complex concepts and provide at-a-glance recognition of disease processes.

- Contains numerous algorithms that provide quick and easy retrieval of diagnostic, screening, and treatment information.

- Provides up-to-date information on indigenous flora and the gut microbiome and clinical correlations to treatment, as well as advancements in liver transplantation including split liver transplantation (SLT) and living donor liver transplantation (LDLT).

- Details key procedures such as esophagogastroduodenoscopy and related techniques; colonoscopy and polypectomy; endoscopic retrograde cholangiopancreatography; capsule endoscopy and small bowel enteroscopy; gastrointestinal pathology; and more. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Table of Contents

1 Biologic Aspects of Gastrointestinal Function

1. Development of the Gastrointestinal Tract � Jaime Belkind-Gerson

2. Basics Aspects of Digestion and Absorption � Ghassan T. Wahbeh and Nicole Green

3. Bile Acid Physiology and Alterations in the Enterohepatic Circulation � James E. Heubi

4. The Gut Microbiome in Pediatrics � Gail A. M. Cresci and Jonathan E. Teitelbaum

5. Gastrointestinal Mucosal Immunology and Mechanisms of Inflammation � Simon Murch

2 Clinical Problems

6. Chronic Abdominal Pain of Childhood and Adolescence � Miguel Saps and Peter L. Lu

7. Approach to the Child with a Functional Gastrointestinal Disorder � Paul E. Hyman and Neha R. Santucci

8. Vomiting and Nausea � Jasmeet Mokha

9. Diarrhea � Peter Townsend and Melissa Fernandes

10. Colic and Gastrointestinal Gas � Sandeep K. Gupta

11. Functional Constipation and Incontinence � Marc A. Benninga

12. Failure to Thrive � Rebecca N. Cherry

13. Gastrointestinal Hemorrhage � Petar Mamula, Joel Aaron Friedlander and Benjamin Sahn

14. Obesity � Joseph Skelton and Gail Cohen

15. Eating Disorders in Children and Adolescents � Ellen S. Rom

16. Jaundice: Unconjugated Hyperbilirubinemia � Cara Mack and Glenn R. Gourley

17. Ascities � David Piccoli and Henry Lin

18. Caustic Ingestion and Foreign Bodies � Michael A. Manfredi

3 The Esophagus

19. Developmental Anatomy and Physiology of the Esophagus � Kristin Nicole Fiorino

20. Congenital Malformations of the Esophagus � Arnold G. Coran, Shaun Michael Kunisaki and Steven W. Bruch

21. Gastroesophageal Reflux � Yvan Vandenplas

22. Achalasia and Other Motor Disorders � Manu R. Sood and Diana G. Lerner,

23. Other Diseases of the Esophagus � Franziska Mohr and Katherine Baldwin

4 The Stomach

24. Developmental Anatomy and Physiology of the Stomach � Christina S. Wills

25. Congenital Anomalies and Surgical Disorders of the Stomach � Federico G. Seifarth

26. Gastritis, Gastropathy, and Ulcer Disease � Quin Y. Liu and Travis Piester

27. Helicobacter Pylori in Childhood � S�amus Hussey and Eileen Crowley

28. Gastric Motility Disorders � Carlo Di Lorenzo and Peter L. Lu

29. Bezoars � Adam G. Mezoff and Ethan Mezoff

5 The Small and Large Intestine

30. Anatomy and Physiology of the Small and Large Intestines � Rose Lee and Ethan Mezoff

31. Maldigestion and Malabsorption � Steven H. Erdman and Tracy R. Ediger

32. Protracted Diarrhea � David Piccoli and Lindsey Albenberg

33. Protein-Losing Enteropathy � David Piccoli

34. Celiac Disease � Riccardo Troncone and Renata Auricchio

35. Short Bowel Syndrome � Robert S. Venick

36. Small Bowel Transplant � Kareem Abu Elmagd and Girlanda Raffaelle

37. Allergic and Eosinophilic Gastrointestinal Disease � Chris A. Liacouras, Rajitha Devadoss Venkatesh, Jonathan E. Markowitz and Lindsay Marie Moye

38. Infectious Diarhea � Mitchell B. Cohen and David Galloway

39. Enteric Parasites � Dorsey M. Bass and Rachel Ruiz

40. Gastrointestinal Manifestations of Primary Immunodeficiency - Gastrointestinal Complications of Secondary Immunodeficiency Syndromes � Athos Bousvaros and Ivan Fuss

41. Pediatric Polyposis Syndromes � Warren Hyer

42. Crohn's Disease � Jennifer L. Dotson and Brendan Boyle

43. Ulcerative Colitis in Children and Adolescents � James F. Markowitz and Samuel Bitton

44. Chronic Intestinal Pseudo-Obstruction � Hayat Mousa, Maheen Hassan and Peter L. Lu

45. Neonatal Necrotizing Enterocolitis � Ricardo J. Rodriguez and Sabine Iben

46. Disorders of the Anorectum: Fissures, Fistulas, Prolapse, Hemorrhoids, Tags � Marian D. Pfefferkorn and Sharon McPheeters

47. Neoplasms of the Gastrointestinal Tract � Jacob A. Kurowski and Praveen Kumar Conjeevaram Selvakumar

48. Neoplasms of the Liver � Karen F. Murray and Hengqi (Betty) Zheng

49. Other Diseases of the Small Intestine and Colon � Orhan Atay

50. Appendicitis � Michael Gerard Caty

6 Pediatric Surgical Disorders

51. Intussusception in Infants and Children � Todd Ponsky and Sophia Abdulhai

52. Inguinal Hernias and Hydroceles � Christine Rader and Jacob Campbell

53. Meckel's Diverticulum and Other Omphalomesenteric Duct Remnants � Brendan T. Campbell and Jennifer Brewer

54. Hirschsprung's Disease � Jacob C. Langer

55. Imperforate Anus � Andrea Bischoff and Alberto Pena

56. Abnormal Rotation and Fixation of the Intestine � Thomas T. Sato and Eleanor H. Sato

57. Small and Large Bowel Stenosis and Atresias � Keith T. Oldham and Ruchi Amin

58. Newborn Abdominal Wall Defects � Jaimie D. Nathan and Stephanie Polites

59. Stomas of the Small and Large Intestine � Anthony L. Deross

7 Gastrointestinal Procedures

60. Esophagogastr Oduodenoscopy, and Related Techniques � Marsha Kay, Robert Wyllie III and Natalie Bhesania

61. Colonoscopy, Polypectomy, and Related Techniques � Marsha Kay, Robert Wyllie III and Jessica Barry

62. Endoscopic Retrograde Cholangiopancreatography � Douglas G. Adler and Atif Saleem, Mounif El-Youssef, Todd H. Baron

63. Capsule Endoscopy and Small Bowel Enteroscopy � Bradley Barth and Isabel ROJAS

64. Gastrointestinal Motility Procedures � Samuel Nurko

65. Gastrointestinal Pathology � Robert E. Petras, Thomas Plesec and Erica C. Savage

66. Liver Pathology � Thomas Plesec and Michael Cruise

8 The Liver and Bile Ducts

67. Developmental Anatomy and Physiology of the Liver and Bile Ducts � Sanjiv Harpavat

68. Neonatal hepatitis � Vicky Lee Ng and Mohit Kehar

69. Biliary Atresia and Neonatal Disorders of the Bile Ducts � Giorgina Mieli-Vergani and Nedim Hadzic

70. Pediatric Cholestatic Liver Disease with Genetic Etiology � Karan McBride Emerick and Kathleen M. Loomes

71. Mitochondrial Hepatopathies: Disorders of Fatty Acid Oxidation and the Respiratory Chain � Patrick McKiernan

72. Abronmalities of Hepatic Protein Metabolism � Fayez K. Ghishan

73. Abnormalities of Carbohydrate Metabolism and the Liver � Shikha S. Sundaram

74. Nonalcoholic Fatty Liver Disease � Ariel Feldstein

75. Acute and Chronic Hepatitis � Maureen M. Jonas and Rima Fawaz

76. Portal Hypertension � Estella Alonso and Lee M. Bass

77. Liver Failure � Suz Warner and Deidre Kelly

78. Liver Transplantation in Children � Koji Hashimoto, Bijan Eghtesad and John Fung

79. Diseases of the Gallbladder � Douglas S. Fishman and Frances Lee

9 The Pancreas

80. Pancreatic Development � Sohail Z. Husain and John Eisses

81. Cystic Fibrosis and Congenital Anomalies of the Exocrine Pancreas � Joel R. Rosh, Sarah Shrager Lusman and Nadia Ovchinsky

82. Pancreatitis � Maisam Abu-El-Haija and David Vitale

83. Total Pancreatectomy with Autoislet Transplantation, and Pancreatic Allotransplantation � R. Matthew Walsh

84. Secretory Neoplasms of the Pancreas � Allan Siperstein

85. Infant and Toddler Nutrition � Susan S. Baker and Robert D. Baker

10 Nutrition

86. Nutritional Assessment � Kate A. Samela

87. Tubes for Enteric Access � Donald E. George and Sina Ogholikhan

88. Parenteral Nutrition � Maria R. Mascarenhas and Jennifer Panganiban

89. Enteral Nutrition � Neal S. LeLeiko and Carolina S. Cerezo

90. Management of Diarrhea � David Devadason

91. Effects of Digestive Diseases on Bone Metabolism � Francisco A. Sylvester

92. Nutrition and Feeding for Children with Developmental Disabilities � Ryann Mayer and Donna Zeiter

93. Fecal Transplant � Zev Davidovics

94. Questions

Eugene Vortia


Robert Wyllie Chief of Medical Operations, Associate Chief of Staff, Cleveland Clinic, Professor of Pediatrics, Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio. Jeffrey S. Hyams Head, Division of Digestive Diseases, Hepatology, and Nutrition, Connecticut Children's Medical Center, Hartford, Connecticut; Professor of Pediatrics, University of Connecticut School of Medicine, Farmington, Connecticut. Marsha Kay Chair, Department of Pediatric Gastroenterology and Nutrition, Director, Pediatric Endoscopy, Cleveland Clinic Children's Hospital, Cleveland, Ohio.