Outsourcing drug discovery is the beginning phase of the drug development process. Through outsourcing portions of their drug discovery programs, many pharmaceutical and biotechnology companies have found an effective cost-cutting strategy that can also improve the hit-to-lead conversion and early identification of unsuccessful compounds. In view of the fact that outsourcing can accelerate the drug discovery process, the business of contract drug discovery has evolved from providing low-end research services to more value-added high-end research.
The pharmaceutical industry has a long history of outsourcing non-core functions. However, over the past two decades, this pattern changed as companies began routinely outsourcing a number of core functions, such as clinical trial management, and manufacturing. Although drug discovery is one of the more recent core functions to be outsourced, increasingly portions of the drug discovery process are being outsourced today.
Current trends in the pharmaceutical industry and the broader global economy are creating new opportunities as well as challenges for drug developers.
Pharmaceutical and biopharmaceutical companies outsource to contract research organizations (CROs) certain R&D functions to gain expertise in specialized knowledge in technology for a particular therapeutic area, for clinical trials, or for regulatory affairs in a particular country or territory. Outsourcing has been used in the pharmaceutical industry for more than 20 years. However, outsourcing drug discovery functions, typically considered a core in-house function, has a more recent history. Outsourcing in Drug Discovery looks at the role of a CRO, outsourcing models, the need for effective communication for a successful partnership, and the challenges of protecting IP rights.
The globalization of contract drug discovery is advancing quickly. A growing number of international CROs have expanded into Asia through alliances or acquisitions, while others are building new facilities in Asia. The report explores the robust growth of outsourcing drug discovery in Asia, specifically outsourcing to China and India. Outsourcing to Eastern Europe is examined as well.
In today's environment, no market report would be complete without discussion of the impact of the outbreak of coronavirus and its resultant disease, COVID-19.
Outsourcing in Drug Discovery provides an in-depth look into the trends that are shaping the drug discovery outsourcing market today, and details the current and future global market, including:
Global Drug Discovery Outsourcing Market, 2019 - 2024 ($ billion)
- Contract Drug Discovery Services, by Market Segment, 2019 - 2024 (Chemistry, Biology, HTS, Lead Optimization, Total Market)
- Market Share of Drug Discovery Market Segments, 2019, in Percent (Chemistry, Biology, HTS, Lead Optimization)
- Market Share of Drug Discovery Market Segments, 2024, in Percent (Chemistry, Biology, HTS, Lead Optimization)
Chemistry Services Market
- Chemistry Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market, 2019 - 2024 ($ billion)
- Chemistry Market Revenue by: Building Blocks, Compound Synthesis, Libraries, Process Research, and Other Services, 2019 ($ billion)
Biology Services Market
- Biology Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market, 2019 - 2024 ($ billion)
- Biology Market Revenue by: Protein Expression, Structural Analysis, Target Validation, Pathways Analysis, and Other Service, 2019 ($ billion)
High Throughput Screening Services Market
- HTS Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market, 2019 - 2024 ($ billion)
- HTS Screening Services Market: Assay Development, Primary Screening, Secondary Screening, 2019 ($ million)
Lead Optimization Services Market
- Lead Optimization Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market, 2019 - 2024 ($ billion)
- Lead Optimization Services Market: Early ADMET/Tox, Create Analogues, Computational Support, and Other Services, 2019 ($ billion)
The pharmaceutical industry has a long history of outsourcing non-core functions. However, over the past two decades, this pattern changed as companies began routinely outsourcing a number of core functions, such as clinical trial management, and manufacturing. Although drug discovery is one of the more recent core functions to be outsourced, increasingly portions of the drug discovery process are being outsourced today.
Current trends in the pharmaceutical industry and the broader global economy are creating new opportunities as well as challenges for drug developers.
The report examines key trends that have led to an increase in demand for contract services in drug discovery, including:
- Development of new technologies that continue to increase the number of targets and accelerate the identification of active compounds;
- Pressure to develop new lead compounds due to the near-term loss of patent protection for many drug products;
- Imperatives to reduce the time spent in drug discovery and bring drugs to market sooner; and
- Increased focus on converting fixed costs to variable costs and streamlining operations by contracting research and development services.
Pharmaceutical and biopharmaceutical companies outsource to contract research organizations (CROs) certain R&D functions to gain expertise in specialized knowledge in technology for a particular therapeutic area, for clinical trials, or for regulatory affairs in a particular country or territory. Outsourcing has been used in the pharmaceutical industry for more than 20 years. However, outsourcing drug discovery functions, typically considered a core in-house function, has a more recent history. Outsourcing in Drug Discovery looks at the role of a CRO, outsourcing models, the need for effective communication for a successful partnership, and the challenges of protecting IP rights.
The globalization of contract drug discovery is advancing quickly. A growing number of international CROs have expanded into Asia through alliances or acquisitions, while others are building new facilities in Asia. The report explores the robust growth of outsourcing drug discovery in Asia, specifically outsourcing to China and India. Outsourcing to Eastern Europe is examined as well.
Outsourcing in Drug Discovery provides profiles containing history and lines of business, drug discovery services, and financial data of the following competitors in the market:
- Albany Molecular Research, Inc.
- Aptuit, a Division of Evotec AG
- Asclepia MedChem Solutions
- Asinex Ltd.
- AsisChem Inc.
- Aurelia Bioscience Ltd
- Axxam SpA
- BioDuro
- Charles River Laboratories, Inc.
- Charnwood Molecular
- ChemBridge Corp.
- Chemical Diversity Inc. (ChemDiv)
- ChemPartner Co., Ltd., subsidiary of ShangPharma
- Chengdu Pioneer Drug Development Co., Ltd.
- Covance Inc. (Laboratory Corporation of America)
- CreaGen Biosciences, Inc.
- Crown Bioscience
- Cyprotex PLC, an Evotec AG Company
- Domainex
- Enamine Ltd.
- Eurofins Scientific S.E.
- Evotec AG
- Exelgen Discovery
- GVK Biosciences Private Limited (GVK Bio)
- GenScript USA Inc.
- Hutchison MediPharma, Ltd.
- Jubilant Biosys Ltd. (JBL), a subsidiary of Jubilant Life Sciences Ltd.
- Nanosyn, Inc.
- Olon Ricerca Biosciences
- Pharmaron, Inc.
- Selcia Ltd
- Selvita S.A.
- Shanghai Medicilon, Inc.
- Sundia MediTech Company, Ltd.
- Sygnature Discovery Limited
- TCG Lifesciences Pvt Ltd.
- Viva Biotech, Ltd.
- WuXi AppTec Co. Ltd.
In today's environment, no market report would be complete without discussion of the impact of the outbreak of coronavirus and its resultant disease, COVID-19.
The report examines the impact of the virus across a spectrum of issues affecting the outsourcing market:
- Global Macro Trends and Coronavirus
- Supply Chain Impact of Coronavirus
- Cultural Implications of Coronavirus
- R&D Spending and Impact of Coronavirus
- Opportunities Created by the Coronavirus
- Issues Related to Coronavirus in Terms of Outsourcing to China, India, or Eastern Europe
Table of Contents
1: EXECUTIVE SUMMARY
2: INTRODUCTION TO OUTSOURCING DRUG DISCOVERY
3: THE DRUG DISCOVERY PROCESS
4: OUTSOURCING DRUG DISCOVERY
5: DRUG DISCOVERY OUTSOURCING MARKET
6: COMPETITOR PROFILES
APPENDIX: COMPANY NAMES AND ADDRESSES
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Companies Mentioned
- 2-Y Chem, Ltd.
- Abgenix
- Abmax Biotechnology
- Absorption Systems
- Acesys Pharmatech
- Actimus Biosciences Pvt. Ltd.
- Activx Biosciences
- Advinus Therapeutics Pvt. Ltd
- Affinium Pharmaceuticals
- Agios Pharmaceuticals
- Albany Molecular Research, Inc.
- Albermarle Corp.
- Alphora Research Inc.
- Ambit Biosciences Corp.
- Amgen, Inc.
- Antabio Pharmaceutical
- Apredica
- Aptuit, A Division Of Evotec Ag
- Aptuit, Llc
- Asclepia
- Asclepia Medchem Solutions
- Asinex Ltd
- Asischem Inc
- Asischem, Inc.
- Astex Therapeutics
- Astrazeneca
- Asymchem Laboratories Co., Ltd
- Asymchem Laboratories Inc.
- Aurelia Bioscience Ltd
- Aurigene Discovery Technologies Ltd.
- Axxam Spa
- Berg Health
- Bioanalab Limited
- Bioblocks Incorporated
- Biocentrum Cell Laboratories, A Division Of Selvita S.A.
- Biocius Life Sciences, Inc
- Bioduro, Inc
- Biogen Idec
- Biolog, Inc.
- Bioneeds
- Bionomics Ltd.
- Bioreliance Corporation
- Biovays Sas
- Biovision Ag
- Boehringer Ingelheim Pharmaceuticals, Inc.
- British Columbia Cancer Agency
- Caliper Life Sciences
- Cambridge Antibody
- Cambridge Major Laboratories, Inc
- Cantab Biopharmaceuticals Ltd,
- Carysbio Holding Ltd.
- Cayman Chemical
- Celera Genomics
- Cell & Molecular Technologies
- Cellcentric Ltd
- Cellzome Ag
- Cetek Corp.
- Charles River Laboratories, Inc
- Charnwood Molecular
- Chembiotek
- Chembridge Corp.
- Chemdiv
- Chemical Diversity Inc. (Chemdiv)
- Chemizon Ltd
- Chemmodeling, Llc..
- Chemotargets Sl
- Chemovation Ltd.
- Chempartner Co., Ltd., Subsidiary Of Shangpharma
- Chemshop Bv
- Chengdu Pioneer Drug Development Co., Ltd.
- Chiesi Farmaceutici Sp
- Comgenex Inc
- Compugen
- Covance, Inc
- Creagen Biosciences, Inc
- Creative Biostructure
- Cresset Drug Discovery.
- Crown Bioscience Inc.
- Curagen Corp.
- Cychem, Inc
- Cyprotex Plc, An Evotec Ag Company
- Dalton Chemical Laboratories Inc.
- Debiopharm International Sa
- Deltagen
- Discoverybiomed, Inc.
- Domainex
- Doubletwist Inc.
- Dr. Reddy’S Laboratories, Ltd.
- Dynogen Pharmaceuticals, Inc.
- Elan Pharmaceuticals
- Elexopharm Gmbh
- Ely Lilly And Company
- Em Industries, Inc.
- Emerald Biostructures
- Enamine Llc
- Endo Pharmaceutical
- Ensemble Discovery Corporation
- Epiclone, L.A.
- Eurofins Advinus Limited
- Eurofins Scientific S.E.
- Evolus Inc.
- Evotec (Asia) Pte. Ltd.
- Evotec (India) Private Limited
- Evotec Ag
- Exelgen Discovery
- Exonhit Therapeutics Sa
- Exsar
- Exscientia
- Flourous Technologies
- Galapagos Nv
- Gene Logic Inc
- Geneformatics Inc.
- Genentech, Inc.
- Geneprot
- Genezyme Corporation
- Genome Biosciences, Inc
- Genome Therapeutics
- Genomics Collaborative Inc
- Genops Bioinformatics Inc.
- Genoway
- Genscript Biotech Corporation
- Genta, Inc.
- Gilead Sciences
- Glaucus Proteomics Bv
- Glaxosmithkline
- Gpc Biotech Ag
- Graffinity Pharmaceuticals Gmbh
- Grünenthal Group
- Gvk Biosciences Private Ltd.
- Hd Biosciences, Inc.
- Hitgen Ltd.
- Human Genome Sciences
- Hutchison Medipharma, Ltd
- Hybrigen
- Hybrigenics Sa
- Icagen, Inc.
- Iconix Pharmaceuticals, Inc
- Icos Corporation
- Id Business Solutions Ltd
- Indus Bioscience
- Informax Inc.
- Inovacia
- Inpharmatica
- Insilico
- Interchem
- Ithemba Pharma
- J-Star Research
- Janssen Pharma
- Johnson & Johnson
- Johnson Matthey Pharma Services
- Jubilant Biosys Ltd. (Jbl), A Subsidiary Of Jubilant Life Sciences Ltd.
- Jubilant Life Sciences Ltd
- Julilant Biosys Ltd.
- Julilant Discovery Center (Noida)
- Kalexsyn
- Kendle International.
- Key Organics Ltd
- Laboratory Corporation Of America Holdings
- Lancaster Laboratories.
- Lark Technologies, Inc
- Laxai Avanti Life Sciences
- Laxai Corporation
- Lexicon Genetics Inc.
- Life Chemicals Inc.
- Ligand Pharmaceuticals, Inc.
- Linden Bioscience
- Magellan Laboratories
- Maybridge Plc
- Medarex
- Medicilon, Inc.
- Merck Kgaa
- Merlion Pharmaceuticals Pte Ltd
- Merrimack Pharmaceuticals, Inc..
- Metabometrix Ltd.
- Micron Technologies, Inc.
- Morphochem Ag
- Mpi Research
- Multispan, Inc
- Myriad Genetics Inc.
- Naeja Pharmaceutical Inc.
- Nanostream, Inc.
- Nanosyn, Inc
- Nanosyn, Inc.
- Navigen Pharma
- Neomed Institute
- Neurodegeneration Consortium
- Nextgen Sciences Ltd
- Nicholas Piramal India Limited
- Nikem Research S.R.L.
- Nitromed, Inc.
- Novartis Institute Of Biomedical Research
- Numerate, Inc
- Nycomed Gmbh
- Olon Ricerca Biosciences
- Oncodesign Sa
- Opgen
- Organix Inc.
- Organomed Corp
- Orion Pharmaceuticals
- Oxford Glycosciences Plc
- Parexel
- Pcovery
- Peakdale Molecular Ltd.
- Peptech Corporation
- Pfizer, Inc
- Pharmacore
- Pharmalink
- Pharmaron Beijing Co., Ltd
- Pharmeco
- Pharmidex
- Phenomix Corp.
- Phylos Inc.
- Polyphor Ltd
- Ppd, Inc.
- Precos Ltd.
- Prestwick Chemical
- Procter And Gamble Company
- Protein Mechanics, Inc.
- Proteologics Ltd.
- Proteome Systems Ltd
- Proteometrics Inc.
- Protogene Laboratories Inc
- Provid Pharmaceuticals Inc
- Purely Proteins
- Pyxis Discovery
- Quantum Pharmaceuticals
- Quintiles Transnational Corp.
- Regulus Therapeutics
- Reliance Life Sciences
- Renovis
- Rib-X Pharmaceuticals
- Ricerca, Llc
- Rmc Biosciences, Inc.
- Roche R&D Center Ltd
- Sai Advantium Pharma Ltd
- Scottish Biomedical
- Scynexis, Inc.
- Selcia Limited
- Selcia Ltd
- Selciawest
- Selvita S.A.
- Sequenom
- Sequitur, Inc.
- Shanghai Genmed
- Shanghai Genomics
- Shanghai Leadchem, Subsidiary Of Shanghai Leaddiscovery Pharmaceutical, Ltd
- Shanghai Medicilon, Inc.
- Shanghai United Pharmatech.
- Shasun Pharmaceuticals Ltd.
- Shenogen Pharma Group
- Shionogi & Co., Ltd.
- Shire Plc
- Signature Bioscience Inc
- Simulations Plus, Inc.
- Somalogic Inc
- Southern Research Institute
- Specs
- Spectrum Bioscience
- Sri Biosciences
- Structural Bioinformatics, Inc.
- Structural Genomix
- Sun Pharma Advanced Research Company
- Sundia Meditech Company, Ltd
- Sunesis Pharmaceuticals
- Suven Life Sciences Ltd
- Sygnature Discovery Limited
- Synaptica Ltd.
- Syngene International Pvt. Ltd.
- Syrrx
- Targeted Molecules Corp.
- Tcg Lifesciences Limited
- Tcg Lifesciences Pvt Ltd.
- Torcan Chemical Ltd.
- Transform Pharmaceuticals Inc.
- Venturepharm Group
- Vertex Pharmaceuticals Inc
- Viva Biotech, Ltd.
- Vivo Biosciences Inc.
- Wuxi Apptec Co. Ltd
- Xencor
- Yangtze River Pharmacy Group Co
- Zobio Bv
- Zygogen, Llc
