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Short Bowel Syndrome - Pipeline Review, H1 2020

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    Drug Pipelines

  • 70 Pages
  • June 2020
  • Region: Global
  • Global Markets Direct
  • ID: 5130270
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Summary

The publisher's latest Pharmaceutical and Healthcare disease pipeline guide Short Bowel Syndrome - Pipeline Review, H1 2020, provides an overview of the Short Bowel Syndrome (Gastrointestinal) pipeline landscape.

Short bowel syndrome is a complex disease that occurs due to the physical loss or the loss of function of a portion of the small and/or large intestine. Symptoms include bloating, cramping, fatigue, heartburn, vomiting, weakness and diarrhea. Complications of short bowel syndrome include malnutrition, peptic ulcers, kidney stones and small intestinal bacterial overgrowth. Treatment includes vitamin and mineral supplements, antibiotics, proton pump inhibitors and bile-salt binders.

Report Highlights

The publisher's Pharmaceutical and Healthcare latest pipeline guide Short Bowel Syndrome - Pipeline Review, H1 2020, provides comprehensive information on the therapeutics under development for Short Bowel Syndrome (Gastrointestinal), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Short Bowel Syndrome (Gastrointestinal) pipeline guide also reviews of key players involved in therapeutic development for Short Bowel Syndrome and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical and Discovery stages are 2, 1, 3, 1, 6 and 1 respectively.

Short Bowel Syndrome (Gastrointestinal) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from the publisher's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content/sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope
  • The pipeline guide provides a snapshot of the global therapeutic landscape of Short Bowel Syndrome (Gastrointestinal).
  • The pipeline guide reviews pipeline therapeutics for Short Bowel Syndrome (Gastrointestinal) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Short Bowel Syndrome (Gastrointestinal) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Short Bowel Syndrome (Gastrointestinal) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Short Bowel Syndrome (Gastrointestinal)

Reasons to Buy
  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Short Bowel Syndrome (Gastrointestinal).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Short Bowel Syndrome (Gastrointestinal) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.

Table of Contents

  • Introduction
  • Report Coverage
  • Short Bowel Syndrome - Overview
  • Short Bowel Syndrome - Therapeutics Development
  • Pipeline Overview
  • Pipeline by Companies
  • Products under Development by Companies
  • Short Bowel Syndrome - Therapeutics Assessment
  • Assessment by Target
  • Assessment by Mechanism of Action
  • Assessment by Route of Administration
  • Assessment by Molecule Type
  • Short Bowel Syndrome - Companies Involved in Therapeutics Development
9 Meters Biopharma Inc
  • enGene Inc
  • Hanmi Pharmaceuticals Co Ltd
  • Huons Global Co Ltd
  • Micelle BioPharma Inc
  • OPKO Health Inc
  • PhaseBio Pharmaceuticals Inc
  • Takeda Pharmaceutical Co Ltd
  • Tasly Pharmaceutical Group Co Ltd
  • VectivBio Holding AG
  • Worphmed Srl
  • Zealand Pharma AS
  • Short Bowel Syndrome - Drug Profiles
  • apraglutide - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • exenatide - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • Fusion Protein to Agonize GLP2R for Short Bowel Syndrome - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • Gene Therapy for Short Bowel Syndrome - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • glepaglutide - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • GXG-8 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • HL-06 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • HM-15912 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • melatonin - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • MOD-1501 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • NB-1002 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • SC-403 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • teduglutide - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • ZP-7570 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • Short Bowel Syndrome - Dormant Projects
  • Short Bowel Syndrome - Discontinued Products
  • Short Bowel Syndrome - Product Development Milestones
  • Featured News & Press Releases
  • Feb 10, 2020: The Scottish Medicines Consortium advises on newly licensed medicine Revestive for use by NHSScotland
  • Jun 26, 2019: Zealand Pharma doses first subject in Phase 1 clinical trial with potential next generation dual-acting peptide therapeutic for short bowel syndrome
  • May 17, 2019: Therachon to present data from ongoing Phase II Study of Apraglutide for Short Bowel Syndrome at Digestive Disease Week
  • May 17, 2019: U.S. FDA approves GATTEX (teduglutide) for children 1 year of age and older with Short Bowel Syndrome
  • May 07, 2019: Zealand Pharma enrolls first patient in Phase 3 extension study of glepaglutide for treatment for short bowel syndrome
  • May 03, 2019: Hanmi's short bowel syndrome treatment becomes orphan drug in US
  • Mar 25, 2019: Therachon presents data from preclinical and phase I clinical studies of Apraglutide for the treatment of Short Bowel Syndrome at ASPEN 2019 Nutrition Science & Practice Conference
  • Feb 05, 2019: Pharm-Olam enrolls patients in Zealand Pharma orphan drug study
  • Jan 16, 2019: Therachon is granted Orphan Drug Designation by US FDA for Apraglutide for the treatment of Short Bowel Syndrome
  • Nov 29, 2018: Therachon is granted Orphan Drug Designation in the European Union for apraglutide for the treatment of short bowel syndrome
  • Nov 13, 2018: U.S. FDA accepts for filing Shire's supplemental New Drug Application for GATTEX (teduglutide [rDNA origin]) for children with Short Bowel Syndrome
  • Oct 05, 2018: Zealand Pharma enrols first patient in Phase lll study of glepaglutide
  • May 31, 2018: Zealand Pharma to present new clinical Phase 2 results on glepaglutide for the treatment of short bowel syndrome at the DDW conference in the U.S.
  • Apr 26, 2018: Zealand announces successful End-of-Phase 2 meeting with FDA on glepaglutide for short bowel syndrome
  • Apr 09, 2018: Revestive is accepted for restricted use within NHS Scotland
  • Appendix
  • Methodology
  • Coverage
  • Secondary Research
  • Primary Research
  • Expert Panel Validation
  • Contact
  • Disclaimer

List of Tables
  • Number of Products under Development for Short Bowel Syndrome, H1 2020
  • Number of Products under Development by Companies, H1 2020
  • Products under Development by Companies, H1 2020
  • Products under Development by Companies, H1 2020 (Contd..1), H1 2020
  • Number of Products by Stage and Target, H1 2020
  • Number of Products by Stage and Mechanism of Action, H1 2020
  • Number of Products by Stage and Route of Administration, H1 2020
  • Number of Products by Stage and Molecule Type, H1 2020
  • Short Bowel Syndrome - Pipeline by 9 Meters Biopharma Inc, H1 2020
  • Short Bowel Syndrome - Pipeline by enGene Inc, H1 2020
  • Short Bowel Syndrome - Pipeline by Hanmi Pharmaceuticals Co Ltd, H1 2020
  • Short Bowel Syndrome - Pipeline by Huons Global Co Ltd, H1 2020
  • Short Bowel Syndrome - Pipeline by Micelle BioPharma Inc, H1 2020
  • Short Bowel Syndrome - Pipeline by OPKO Health Inc, H1 2020
  • Short Bowel Syndrome - Pipeline by PhaseBio Pharmaceuticals Inc, H1 2020
  • Short Bowel Syndrome - Pipeline by Takeda Pharmaceutical Co Ltd, H1 2020
  • Short Bowel Syndrome - Pipeline by Tasly Pharmaceutical Group Co Ltd, H1 2020
  • Short Bowel Syndrome - Pipeline by VectivBio Holding AG, H1 2020
  • Short Bowel Syndrome - Pipeline by Worphmed Srl, H1 2020
  • Short Bowel Syndrome - Pipeline by Zealand Pharma AS, H1 2020
  • Short Bowel Syndrome - Dormant Projects, H1 2020
  • Short Bowel Syndrome - Discontinued Products, H1 2020

List of Figures
  • Number of Products under Development for Short Bowel Syndrome, H1 2020
  • Number of Products under Development by Companies, H1 2020
  • Number of Products by Top 10 Targets, H1 2020
  • Number of Products by Stage and Top 10 Targets, H1 2020
  • Number of Products by Top 10 Mechanism of Actions, H1 2020
  • Number of Products by Stage and Top 10 Mechanism of Actions, H1 2020
  • Number of Products by Top 10 Routes of Administration, H1 2020
  • Number of Products by Stage and Top 10 Routes of Administration, H1 2020
  • Number of Products by Top 10 Molecule Types, H1 2020
  • Number of Products by Stage and Top 10 Molecule Types, H1 2020

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • 9 Meters Biopharma Inc
  • enGene Inc
  • Hanmi Pharmaceuticals Co Ltd
  • Huons Global Co Ltd
  • Micelle BioPharma Inc
  • OPKO Health Inc
  • PhaseBio Pharmaceuticals Inc
  • Takeda Pharmaceutical Co Ltd
  • Tasly Pharmaceutical Group Co Ltd
  • VectivBio Holding AG
  • Worphmed Srl
  • Zealand Pharma AS