Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview
Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale.
The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker.
Characterization of Pharmaceutical Nano- and Microsystems deals with a wide variety of topics relevant to chemical and solid-state analysis of drug delivery systems, including drug release, permeation, cell interaction, and safety. It is a complete resource for those interested in the development and manufacture of new medicines, the drug development process, and the translation of those drugs into life-enriching and lifesaving medicines.
Characterization of Pharmaceutical Nano- and Microsystems covers all of the following topics:
- An introduction to the analytical tools applied to determine particle size, morphology, and shape
- Common chemical approaches to drug system characterization
- A description of solid-state characterization of drug systems
- Drug release and permeation studies
- Toxicity and safety issues
- The interaction of drug particles with cells
Perfect for pharmaceutical chemists and engineers, as well as all other industry professionals and researchers who deal with drug delivery systems on a regular basis, Characterization of Pharmaceutical Nano- and Microsystems also belongs on bookshelves of interested students and faculty who interact with this topic.
1. Selecting a Particle Sizer for the Pharmaceutical Industry
Professor Maria Margarida Figuiredo (firstname.lastname@example.org)
2. Spectroscopic methods in solid-state characterization
Professor Clare Strachan (email@example.com)
3. Microfluidic analysis techniques for safety assessment of pharmaceutical nano- and microsystems
Dr Tiina Sikanen(firstname.lastname@example.org)
4. In Vitro In Vivo Correlation for Pharmaceutical Nano and Microsystems
Prof. Vandana Patravale (email@example.com)
5. Characterization of Bioadhesion, Mucin-interactions and Mucosal Permeability of Pharmaceutical Nano- and Microsystems
Ellen Hagesaether, Marianne Hiorth and Prof Ingunn Tho (Ingunn.firstname.lastname@example.org)
6. Cell-Nanoparticle Interactions: Toxicity and Safety Issues
Helder Santos (email@example.com)
7. Intestinal mucosal tissue models to validate functionalized nanosystems
Bruno Sarmento (firstname.lastname@example.org)
8. Biodistribution of polymeric, polysaccharide and metallic nanoparticles
Erem Bilensoy (email@example.com)
9. Opportunities and challenges of silicon-based nanoparticles for drug delivery and imaging
Jessica Rosenholm (firstname.lastname@example.org)
10. Statistical Analysis and Multidimensional Modelling in ResearchOsmo Antikainen (email@example.com)