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Metabolic Engineering. Concepts and Applications. Edition No. 1. Advanced Biotechnology

  • ID: 5214940
  • Book
  • July 2021
  • 800 Pages
  • John Wiley and Sons Ltd
This book provides a comprehensive treatment of the underlying concepts and the practical applications in metabolic engineering. The first part deals with the essential models and strategies, such as Flux Balance Analysis, Quantitative Flux Analysis and Proteome Constrained Models, as well as an overview of relevant topics like Pathway Design, Metabolomics and Genome Editing of Bacteria and Eukarya. The second part provides insight into the practical applications of metabolic engineering, with specific examples for bacterial and mammalian cells, metabolic engineering of animals, humans and plants as well as applications towards bioremediation and biome engineering.
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Part 1: Concepts
Introduction
Metabolic Engineering Concepts and Historical Perspective
Metabolism and Regulation
Reconstruction of Metabolic models
Flux Balance Analysis
Quantitative Flux Analysis
Proteome Constrained Models
Kinetic Models of Metabolism
Metabolic Control Analysis
Thermodynamics of Metabolic Pathways
Pathway Design
Metabolomics
Transcriptomics, Proteomics and multi-omics
Genome Architecture of E. coli
Genome Editing of Bacteria
Genome Editing of Eukarya

Part 2: Applications
Metabolic Engineering of E. coli
Metabolic Engineering of Corynebacteria
Metabolic Engineering of Bacillus
Metabolic Engineering of Pseudomonas
Metabolic Engineering of Lactic Acid Bacteria
Metabolic Engineering of Actinomycetes
Metabolic Engineering of S. cerevisiae
Metabolic Engineering of Yarrowia lipolytica
Metabolic Engineering of Filamentous Fungi
Metabolic Engineering of Mammalian Cells
Metabolic Engineering of Animals and Humans
Metabolic Engineering of Plants
Metabolic engineering in bioremediation
Microbiome engineering
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Sang Yup Lee KAIST,Daejon,Republik Korea.

Jens Nielsen Center for Microbial Biotechnology.

Gregory Stephanopoulos Massachusetts Institute of Technologie, USA.
Note: Product cover images may vary from those shown
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