Interbody Devices - Medical Devices Pipeline Assessment, 2020

1 Table of Contents
1.1 List of Tables
1.2 List of Figures

2 Introduction
2.1 Interbody Devices Overview

3 Products under Development
3.1 Interbody Devices - Pipeline Products by Stage of Development
3.2 Interbody Devices - Pipeline Products by Segment
3.3 Interbody Devices - Pipeline Products by Territory
3.4 Interbody Devices - Pipeline Products by Regulatory Path
3.5 Interbody Devices - Pipeline Products by Estimated Approval Date
3.6 Interbody Devices - Ongoing Clinical Trials

4 Interbody Devices - Pipeline Products under Development by Companies
4.1 Interbody Devices Companies - Pipeline Products by Stage of Development
4.2 Interbody Devices - Pipeline Products by Stage of Development

5 Interbody Devices Companies and Product Overview
5.1 Allegra Orthopaedics Ltd Company Overview
5.1.1 Allegra Orthopaedics Ltd Pipeline Products & Ongoing Clinical Trials Overview
5.2 Alphatec Holdings Inc Company Overview
5.2.1 Alphatec Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview
5.3 Bio2 Technologies Inc Company Overview
5.3.1 Bio2 Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview
5.4 Camber Spine Technologies LLC Company Overview
5.4.1 Camber Spine Technologies LLC Pipeline Products & Ongoing Clinical Trials Overview
5.5 Choice Spine LLC Company Overview
5.5.1 Choice Spine LLC Pipeline Products & Ongoing Clinical Trials Overview
5.6 Corelink LLC Company Overview
5.6.1 Corelink LLC Pipeline Products & Ongoing Clinical Trials Overview
5.7 CTL Amedica Corp Company Overview
5.7.1 CTL Amedica Corp Pipeline Products & Ongoing Clinical Trials Overview
5.8 Cutting Edge Spine LLC Company Overview
5.8.1 Cutting Edge Spine LLC Pipeline Products & Ongoing Clinical Trials Overview
5.9 DePuy Synthes Inc Company Overview
5.9.1 DePuy Synthes Inc Pipeline Products & Ongoing Clinical Trials Overview
5.10 DSM Biomedical BV Company Overview
5.10.1 DSM Biomedical BV Pipeline Products & Ongoing Clinical Trials Overview
5.11 Eminent Spine LLC Company Overview
5.11.1 Eminent Spine LLC Pipeline Products & Ongoing Clinical Trials Overview
5.12 Evoke Medical LLC Company Overview
5.12.1 Evoke Medical LLC Pipeline Products & Ongoing Clinical Trials Overview
5.13 H. Lee Moffitt Cancer Center & Research Institute Inc Company Overview
5.13.1 H. Lee Moffitt Cancer Center & Research Institute Inc Pipeline Products & Ongoing Clinical Trials Overview
5.14 HD LifeSciences LLC Company Overview
5.14.1 HD LifeSciences LLC Pipeline Products & Ongoing Clinical Trials Overview
5.15 Implants International Ltd Company Overview
5.15.1 Implants International Ltd Pipeline Products & Ongoing Clinical Trials Overview
5.16 Inion Oy Company Overview
5.16.1 Inion Oy Pipeline Products & Ongoing Clinical Trials Overview
5.17 Innov'spine Company Overview
5.17.1 Innov'spine Pipeline Products & Ongoing Clinical Trials Overview
5.18 Intelligent Implant Systems LLC Company Overview
5.18.1 Intelligent Implant Systems LLC Pipeline Products & Ongoing Clinical Trials Overview
5.19 Jemo Spine, LLC. Company Overview
5.19.1 Jemo Spine, LLC. Pipeline Products & Ongoing Clinical Trials Overview
5.20 Medacta Group SA Company Overview
5.20.1 Medacta Group SA Pipeline Products & Ongoing Clinical Trials Overview
5.21 Medicrea Group Company Overview
5.21.1 Medicrea Group Pipeline Products & Ongoing Clinical Trials Overview
5.22 MicroPort Scientific Corp Company Overview
5.22.1 MicroPort Scientific Corp Pipeline Products & Ongoing Clinical Trials Overview
5.23 Nexxt Spine LLC Company Overview
5.23.1 Nexxt Spine LLC Pipeline Products & Ongoing Clinical Trials Overview
5.24 Osseus Fusion Systems LLC Company Overview
5.24.1 Osseus Fusion Systems LLC Pipeline Products & Ongoing Clinical Trials Overview
5.25 Ozop Surgical Corp Company Overview
5.25.1 Ozop Surgical Corp Pipeline Products & Ongoing Clinical Trials Overview
5.26 Pharmaco-Kinesis Corp Company Overview
5.26.1 Pharmaco-Kinesis Corp Pipeline Products & Ongoing Clinical Trials Overview
5.27 Precision Spine Inc Company Overview
5.27.1 Precision Spine Inc Pipeline Products & Ongoing Clinical Trials Overview
5.28 Safe Orthopaedics SA Company Overview
5.28.1 Safe Orthopaedics SA Pipeline Products & Ongoing Clinical Trials Overview
5.29 SeaSpine, Inc. Company Overview
5.29.1 SeaSpine, Inc. Pipeline Products & Ongoing Clinical Trials Overview
5.30 SINTX Technologies Inc Company Overview
5.30.1 SINTX Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview
5.31 Spinal Simplicity, LLC Company Overview
5.31.1 Spinal Simplicity, LLC Pipeline Products & Ongoing Clinical Trials Overview
5.32 SpinalVu Inc (Inactive) Company Overview
5.32.1 SpinalVu Inc (Inactive) Pipeline Products & Ongoing Clinical Trials Overview
5.33 SpineFrontier, Inc. Company Overview
5.33.1 SpineFrontier, Inc. Pipeline Products & Ongoing Clinical Trials Overview
5.34 Spineology Inc Company Overview
5.34.1 Spineology Inc Pipeline Products & Ongoing Clinical Trials Overview
5.35 SpineSmith Holdings LLC Company Overview
5.35.1 SpineSmith Holdings LLC Pipeline Products & Ongoing Clinical Trials Overview
5.36 Stryker Corp Company Overview
5.36.1 Stryker Corp Pipeline Products & Ongoing Clinical Trials Overview
5.37 Taragenyx Ltd (Inactive) Company Overview
5.37.1 Taragenyx Ltd (Inactive) Pipeline Products & Ongoing Clinical Trials Overview
5.38 University of South Florida Company Overview
5.38.1 University of South Florida Pipeline Products & Ongoing Clinical Trials Overview
5.39 VGI Medical, LLC Company Overview
5.39.1 VGI Medical, LLC Pipeline Products & Ongoing Clinical Trials Overview
5.40 Xtant Medical Holdings Inc Company Overview
5.40.1 Xtant Medical Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview

6 Interbody Devices- Recent Developments
6.1 Aug 18, 2020: Aurora spine receives notice of allowance for patent: DEXA technology - the world’s first patient-matched interbody implant technology to enable improved spine surgery
6.2 Jun 29, 2020: DePuy Synthes renews cooperation agreement with AO Foundation to continue advancement of surgical education
6.3 May 04, 2020: Safe Orthopaedics announces the progressive lifting of partial activity for its German commercial teams
6.4 Mar 05, 2020: U.S. Attorney sues spinal device company and its executives for allegations that they paid kickbacks to surgeons
6.5 Mar 05, 2020: DOJ files suit against spine device manufacturer and executives alleging kickbacks to surgeons through sham consulting payments
6.6 Mar 03, 2020: Clinical study demonstrates favorable patient outcomes with the FlareHawk Expandable Cage
6.7 Mar 02, 2020: Amplify Surgical reaches milestone of 300 levels treated with dualX Expanding Interbody Fusion System
6.8 Mar 02, 2020: Stryker announces new Investor Relations leader
6.9 Feb 28, 2020: Experience the future of digital surgery with DePuy Synthes and Brainlab
6.10 Feb 25, 2020: Stryker announces nomination of new Director, Lisa Skeete Tatum
6.11 Feb 24, 2020: 2020 Catalyst award winner Medtronic hires Chief Inclusion and Diversity Officer
6.12 Feb 24, 2020: 2020 Catalyst Award Winner Medtronic hires Chief Inclusion and Diversity Officer
6.13 Feb 19, 2020: Integra LifeSciences reports fourth quarter and full-year 2019 financial results and provides 2020 financial guidance
6.14 Feb 18, 2020: Medtronic reports third quarter financial results 2020
6.15 Feb 13, 2020: Results validating the versatility of NuVasive's MaXcess Retractor in Prone Single-Position XLIF and Posterior Fixation published in The European Spine journal
6.16 Feb 12, 2020: 4WEB Medical achieves record revenue in 2019
6.17 Feb 05, 2020: Stryker expands Flower Mound regional headquarters
6.18 Jan 28, 2020: Stryker reports 2019 results and 2020 outlook
6.19 Jan 23, 2020: Safe Orthopaedics : First surgeries with SteriSpine CC & LC completed in Japan
6.20 Jan 23, 2020: Centinel Spine announces continued partnership with Performance Tech Motorsports
6.21 Jan 23, 2020: Safe Orthopaedics : First surgeries with Sterispine CC & LC completed in Japan
6.22 Jan 15, 2020: MEDICREA reports 2019 annual sales
6.23 Jan 13, 2020: Safe Orthopaedics closes 2019 with its best quarterly performance: 1 502 K€, an increase of 52%
6.24 Jan 13, 2020: NuVasive announces preliminary unaudited fourth quarter and full year 2019 revenue results
6.25 Jan 13, 2020: ATEC announces preliminary 2019 revenue results and 2020 revenue outlook
6.26 Jan 10, 2020: World’s first lumbar fusion with 3D printed spinal implant Aries-L
6.27 Jan 08, 2020: Globus Medical reports preliminary record fourth quarter and full year sales results
6.28 Jan 06, 2020: Exactech announces leadership transition
6.29 Jan 02, 2020: NuVasive appoints Matthew K. Harbaugh as chief financial officer
6.30 Dec 17, 2019: RTI Surgical announces The Spine Journal’s Publication of In Vivo TETRAfuse 3D Technology PEKK Study
6.31 Dec 17, 2019: SeaSpine announces 25,000th NanoMetalene Implantation
6.32 Dec 17, 2019: Aurora Spine announces mew chief financial officer
6.33 Dec 13, 2019: Globus Medical announces Board of Director addition and departure
6.34 Dec 04, 2019: Lumeon and Medtronic partner to deliver new models of care in Europe
6.35 Dec 03, 2019: RTI Surgical accelerates business transformation with senior leadership appointments

7 Appendix
7.1 Methodology
7.2 About the Publisher
7.3 Contact
7.4 Disclaimer

List of Tables
Table 1: Interbody Devices - Pipeline Products by Stage of Development
Table 2: Interbody Devices - Pipeline Products by Segment
Table 3: Interbody Devices - Pipeline Products by Territory
Table 4: Interbody Devices - Pipeline Products by Regulatory Path
Table 5: Interbody Devices - Pipeline Products by Estimated Approval Date
Table 6: Interbody Devices - Ongoing Clinical Trials
Table 7: Interbody Devices Companies - Pipeline Products by Stage of Development
Table 8: Interbody Devices - Pipeline Products by Stage of Development
Table 9: Allegra Orthopaedics Ltd Pipeline Products & Ongoing Clinical Trials Overview
Table 10: Spinal Cage Device - Product Status
Table 11: Spinal Cage Device - Product Description
Table 12: Alphatec Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview
Table 13: Lateral Interbody with Expandable Cage - Product Status
Table 14: Lateral Interbody with Expandable Cage - Product Description
Table 15: PCB - Product Status
Table 16: PCB - Product Description
Table 17: Samarys RF - Product Status
Table 18: Samarys RF - Product Description
Table 19: Bio2 Technologies Inc Pipeline Products & Ongoing Clinical Trials Overview
Table 20: Vitrium - Cervical Interbody Fusion Device - Product Status
Table 21: Vitrium - Cervical Interbody Fusion Device - Product Description
Table 22: Vitrium - Lumbar Interbody Fusion Device - Product Status
Table 23: Vitrium - Lumbar Interbody Fusion Device - Product Description
Table 24: Bio2 Technologies Inc - Ongoing Clinical Trials Overview
Table 25: Vitrium - Cervical Interbody Fusion Device - Safety and Effectiveness of Bio2 Vitrium Cervical Cage in Anterior Cervical Discectomy and Fusion. A Randomized, Controlled, Non-inferiority, Pivotal Study
Table 26: Camber Spine Technologies LLC Pipeline Products & Ongoing Clinical Trials Overview
Table 27: SPIRA - Expandable Transforaminal Lumbar Interbody - Product Status
Table 28: SPIRA - Expandable Transforaminal Lumbar Interbody - Product Description
Table 29: SPIRA Open Matrix ALIF - Product Status
Table 30: SPIRA Open Matrix ALIF - Product Description
Table 31: SPIRA-L Open Matrix LLIF - Product Status
Table 32: SPIRA-L Open Matrix LLIF - Product Description
Table 33: Camber Spine Technologies LLC - Ongoing Clinical Trials Overview
Table 34: SPIRA Open Matrix ALIF - SPIRA-A 3D Printed Titanium Anterior Lumbar Interbody Fusion Device and HCT/p Demineralized Bone Matrix Versus Medtronic Divergent-L/Perimeter PEEK Anterior Lumbar Interbody Fusion Device and Recombinant Bone Morphogenic Protein-2
Table 35: Choice Spine LLC Pipeline Products & Ongoing Clinical Trials Overview
Table 36: Expandable PEEK Interbody Cage - Product Status
Table 37: Expandable PEEK Interbody Cage - Product Description
Table 38: Corelink LLC Pipeline Products & Ongoing Clinical Trials Overview
Table 39: 3D Printed Cervical Titanium Interbody System - Product Status
Table 40: 3D Printed Cervical Titanium Interbody System - Product Description
Table 41: 3D Printed Lumbar Titanium Interbody System - Product Status
Table 42: 3D Printed Lumbar Titanium Interbody System - Product Description
Table 43: CTL Amedica Corp Pipeline Products & Ongoing Clinical Trials Overview
Table 44: MONDRIAN PLIF Cage - Product Status
Table 45: MONDRIAN PLIF Cage - Product Description
Table 46: MONDRIAN TLIF Cage - Product Status
Table 47: MONDRIAN TLIF Cage - Product Description
Table 48: Cutting Edge Spine LLC Pipeline Products & Ongoing Clinical Trials Overview
Table 49: EVOL HA-ALIF - Product Status
Table 50: EVOL HA-ALIF - Product Description

List of Figures
Figure 1: Interbody Devices - Pipeline Products by Stage of Development
Figure 2: Interbody Devices - Pipeline Products by Segment
Figure 3: Interbody Devices - Pipeline Products by Territory
Figure 4: Interbody Devices - Pipeline Products by Regulatory Path
Figure 5: Interbody Devices - Pipeline Products by Estimated Approval Date
Figure 6: Interbody Devices - Ongoing Clinical Trials