2. US - Approved Alzheimer's Disease Drugs by Class
2.1 Cholinesterase Inhibitors
2.2 NMDA Receptor Agonist
3. US - New Emerging Therapies in Alzheimer's Disease
3.1 Monoclonal Antibody
3.2 Novel NMDA Receptor Agonists
3.3 Small Molecules Drug
3.4 Oral Semaglutide
4. US - Alzheimer's Disease Generic & Biosimilar Drug Market Landscape
4.1 Current Scenario & Price Differential
4.2 Reimbursement Laws & Regulations
6. Acetylcholinesterases Inhibitor: US Market Availability, Dosage, Patent & Price Insight
6.1 Razadyne (Brand Drug)
6.2 Razadyne ER (Branded)
6.3 Aricept (Brand Drug)
6.4 Aricept ODT (Branded)
6.5 Reminyl (Branded)
6.6 Exelon (Brand Drug)
6.7 Namzaric (Brand Drug)
7. N-methyl-D-aspartate Inhibitors: US Market Availability, Dosage, Patent & Price Insight
7.1 Namenda (Brand Drug)
7.2 Namenda XR (Branded)
8. Approved Generic Drugs for Alzheimer's: US Market Availability, Dosage & Price In
sight
8.1 Galantamine (Generic Drug)
8.2 Donepzil (Generic Drug)
8.3 Rivastigmine (Generic Drug)
8.4 Memantine (Generic Drug)
8.5 Ergoloid Mesylates
9. US - Alzheimer's Disease Drugs Clinical Trials Overview
9.1 By Biomarket
9.2 By Formulation
9.3 By Organization
9.4 By Phase
9.5 By Patient Segment
10. US - Alzheimer’s Disease Drug Clinical Pipeline By Company, Indication & Phase
10.1 Unknown
10.2 Research
10.3 Preclinical
10.4 Clinical
10.5 Phase-I
10.6 Phase-I/II
10.7 Phase-II
10.8 Phase-II/III
10.9 Phase-III
10.10 Preregistration
10.11 Registered
11. US - Marketed Alzheimer’s Disease Drugs Clinical Insight
11.1 Razadyne
11.2 Namenda
11.3 Exelon Patch
11.4 Amyvid
11.5 Namzaric
11.6 Aricept
11.7 NeuraCeq
11.8 Vizamyl
11.9 Cognex
12. US Alzheimer's Disease Drug Market Dynamics
12.1 US Alzheimer's Market Favourable Parameters
12.2 US Alzheimer's Drug Market Challenges
14. Competitive Landscape
14.1 Allergan
14.2 Alvogen
14.3 Dr. Reddy Laboratories
14.4 Eisai Co Ltd
14.5 Hoffmann- La Roche Ltd
14.6 Jassen Pharmaceuticals
14.7 Lupin
14.8 Mylan
14.9 Novartis AG
14.10 Sun Pharma
14.11 Teva Pharmaceuticals
List of Figures
Figure 1-1: US - Alzheimer's Disease Cases (Million) by Age, 2020
Figure 1-2: US - Alzheimer's Disease Expected Cases by Age(%), 2020
Figure 1-3: US - Alzheimer Drug Market Oppotunity (US$ Billion), 2020 - 2026
Figure 1-4: Alzheimer's Drugs – Clinical Pipeline, 2020
Figure 2 -1: Acetylcholinesterase Inhibitors – Mechanism of Action
Figure 2-2: Memantine – Mode of Action
Figure 3-1: Designed Monoclonal Antibodies for Alzheimer Disease Discontinued Till Phase-3 Trials
Figure 4-1: US - Alzheimer's Disease Estimated Cost of Treatment (US$ Billion), 2020
Figure 4-2: Aricept & Donepezil - Cost per Unit (US$ )
Figure 4-3: Namenda & Memantine - Cost per Unit (US$)
Figure 4-4: Namenda & Memantine – Annual Sales (US$ Million), 2019
Figure 4-5: US - Total Cost Care of Alzheimer's Treatment (US$ Billion), 2020
Figure 4-6: US - Alzheimer's Disease In-Pocket Cost & Out-Pocket Cost (%), 2020
Figure 5-1: Drugs for the Alzheimer’s Disease
Figure 6-1: Razadyne – FDA Approval & First Generic Approval Year
Figure 6-2: Razadyne – Cost of 60 Tablets of Dosage 4 mg (US$), January’2021
Figure 6-3: Razadyne – Cost of 60 Tablets of Dosage 8 mg (US$), January’2021
Figure 6-4: Razadyne – Cost of 60 Tablets of Dosage 12 mg (US$), January’2021
Figure 6-5: Razadyne– Price of 100ml Supply & Price per unit ml of Oral Solution (US$), January’2021
Figure 6 -6: Razadyne – Recommended Initial Dose & Incremented Dose (mg/day), January’2021
Figure 6-7: Razadyne – Patent Issue & Patent Expiration by US FDA
Figure 6-8: Razadyne ER – FDA Approval & First Generic Approval Year
Figure 6-9: Razadyne ER – Cost of 30 Tablets of Various Dose Regimens (US$), January’2021
Figure 6-10: Razadyne ER – Recommended Initial Dose & Incremented Dose (mg/day), January’2021
Figure 6-11: Aricept – FDA Approval Year by Dosage Forms
Figure 6-12: Aricept – Price of 30 Tablets of 5mg Drug (US$), January’2021
Figure 6-13: Aricept – Price of 21 Tablets of 10mg Drug (US$), January’2021
Figure 6-14: Aricept – Minimum Price of 30 Tablets of 10mg Drug (US$), January’2021
Figure 6-15: Aricept – Maximum Price of 30 Tablets of 10mg Drug (US$), January’2021
Figure 6-16: Aricept – Price of 30 Tablets of 23mg Drug (US$), January’2021
Figure 6-17: Aricept – Recommended & Incremented Dose for Alzheimer’s Disease (mg/day)
Figure 6-18: Aricept – Time Interval for 1st & 2nd Dose Increment (Weeks)
Figure 6-19: Aricept ODT – Cost of 30 Tablets of Dosage 5 mg (US$), January’2021
Figure 6-20: Aricept ODT – Cost of 30 Tablets of Dosage 10 mg (US$), January’2021
Figure 6-21: Aricept ODT – Recommended Initial & Incremented Dose (mg/day)
Figure 6-22: Aricept ODT – Time Interval Required for Dose Increment (Weeks)
Figure 6-23: Reminyl – USFDA & PMDA Approval Year
Figure 6-24: Reminyl – FDA Approval Year by Dosage Forms
Figure 6-25: Reminyl – Cost of 100ml & Price per ml of Oral Solution (US$), January’2021
Figure 6-26: Reminyl – Cost of 56 Tablet & Price per Tablet of 8mg & 12 mg Dose (US$), January’2021
Figure 6-27: Reminyl – Cost of 112 Tablet & Price per Tablet of 8mg (US$), January’2021
Figure 6-28: Reminyl – Recommended Initial & Incremented Dose (mg/day)
Figure 6-29: Exelon – US FDA & Europe EMEA Approval Year
Figure 6-30: Exelon – FDA Approval Year by Dosage Forms
Figure 6-31: Exelon – Price of 30 Transdermal Films of Dose 4.6 mg/24 hr (US$), January’2021
Figure 6-32: Exelon – Price of 30 Transdermal Films of Dose 9.5 mg/24 hr (US$), January’2021
Figure 6-33: Exelon – Price of 30 Transdermal Films of Dose 13.3 mg/24 hr (US$), January’2021
Figure 6-34: Exelon – Recommended Initial & Incremented Dose (mg/24 Hours)
Figure 6-35: Namzaric – FDA Approval Year by Dose
Figure 6-36: Namzaric – Forest Laboratory’s Patent Issue & Expiration Year
Figure 6-37: Namzaric – Adamas Pharmaceutical’s Patent Issue & Expiration Year
Figure 6-38: Namzaric – Price of 30 Capsules of the Drug of Dosage 7 mg – 10 mg (US$), January’2021
Figure 6-39: Namzaric – Price of 30 Capsules of the Drug of Dosage 10 mg – 14 mg (US$), January’2021
Figure 6-40: Namzaric – Price of 30 Capsules of the Drug of Dosage 10 mg – 21 mg (US$), January’2021
Figure 6-41: Namzaric – Price of 30 Capsules of the Drug of Dosage 10 mg – 28 mg (US$), January’2021
Figure 6-42: Namzaric – Recommended Initial & Incremented Dose Based on Memantine Administration (mg/day)
Figure 7-1: Namenda – FDA Approval Year by Dosage Forms
Figure 7-2: Namenda – FDA Approval & First Generic Approval Year
Figure 7-3: Namenda - Price of 49 Oral Kits (US$), January’2021
Figure 7-4: Namenda - Price of 60 Oral Tablets of Dosage 5mg (US$), January’2021
Figure 7-5: Namenda - Price of 100 Oral Tablets of Dosage 5mg (US$), January’2021
Figure 7-6: Namenda - Price of 60 Oral Tablets of Dosage 10mg (US$), January’2021
Figure 7-7: Namenda - Price of 100 Oral Tablets of Dosage 10mg (US$), January’2021
Figure 7-8: Namenda – Recommended Initial & Incremented Dose (mg/day)
Figure 7-9: US – Namenda Sales (US$ Million), 2016 - 2018
Figure 7-10: Namenda XR – FDA Approval & First Generic Approval Year
Figure 7-11: Namenda XR – Forest Laboratory’s Patent Issue & Expiration Year
Figure 7-12: Namzaric – Adamas Pharmaceutical’s Patent Issue & Expiration Year
Figure 7-13: Namenda XR – Price of 30 Capsules Supply of Various Dose Regimen (US$), January’2021
Figure 7-14: Namenda XR – Price of 90 Capsules Supply of 14mg & 28 mg Dose Regimen (US$), January’2021
Figure 7-15: Namenda XR Kit – Price of 28 Kit Supply & Price per unit Kit (US$), January’2021
Figure 7-16: Namenda XR – Recommended Initial & Incremented Dose (mg/day)
Figure 8-1: Galantamine (Generic Drug) – Cost of 30 capsules of Dosage 8 mg (US$), January’2021
Figure 8-2: Galantamine (Generic Drug) – Cost of 30 capsules of Dosage 16 mg (US$), January’2021
Figure 8-3: Galantamine (Generic Drug) – Cost of 30 capsules of Dosage 24 mg (US$), January’2021
Figure 8-4: Galantamine (Generic Drug) – Cost of 100 ml of Dosage 4 mg/ml (US$), January’2021
Figure 8-5: Galantamine (Generic Drug) – Cost of 30 Tablets of 4mg Dosage (US$), January’2021
Figure 8-6: Galantamine (Generic Drug) – Cost of 30 Tablets of 4mg Dosage (US$), January’2021
Figure 8-7: Galantamine (Generic Drug) – Cost of 60 Tablets of 4mg Dosage (US$), January’2021
Figure 8-8: Galantamine (Generic Drug) – Cost of 60 Tablets of 4mg Dosage (US$), January’2021
Figure 8-9: Galantamine (Generic Drug) – Cost of 30 Tablets of 8 mg Dosage (US$), January’2021
Figure 8-10: Galantamine (Generic Drug) – Cost of 30 Tablets of 8 mg Dosage (US$), January’2021
Figure 8-11: Galantamine (Generic Drug) – Cost of 60 Tablets of 8 mg Dosage (US$), January’2021
Figure 8-12: Galantamine (Generic Drug) – Cost of 60 Tablets of 8 mg Dosage (US$), January’2021
Figure 8-13: Galantamine (Generic Drug) – Cost of 60 Tablets of 12 mg Dosage (US$), January’2021
Figure 8-14: Galantamine (Generic Drug) – Cost of 60 Tablets of 12 mg Dosage (US$), January’2021
Figure 8-15: Galantamine Tablet & Solution – Recommended Initial & Incremented Dose (mg/day), January’2021
Figure 8-16: Galantamine ER – Recommended Initial Dose & Incremented Dose (mg/day), January’2021
Figure 8-17: Donepzil – Price of 30 Tablets of 5 mg Drug (US$), January’2021
Figure 8-18: Donepzil – Price of 30 Tablets of 10 mg Drug (US$), January’2021
Figure 8-19: Donepzil – Price of 90 Tablets of 5 mg Drug (US$), January’2021
Figure 8-20: Donepzil – Price of 100 (10X10 each) Tablets of 5 mg Drug (US$), January’2021
Figure 8-21: Donepzil – Price of 90 Tablets of 10 mg Drug (US$), January’2021
Figure 8-22: Donepzil – Price of 100 Tablets of 10 mg Drug (US$), January’2021
Figure 8-23: Donepzil – Price of 30 Tablets of 23 mg Drug (US$), January’2021
Figure 8-24: Donepzil – Price of 90 Tablets of 23 mg Drug (US$), January’2021
Figure 8-25: Donepzil – Price of 28 (4X7 each) Tablets of 5 mg Drug Disintegrating (US$), January’2021
Figure 8-26: Donepzil – Price of 30 Tablets of 5 mg Drug Disintegrating (US$), January’2021
Figure 8-27: Donepzil – Price of 28 (4X7 each) Tablets of 10 mg Drug Disintegrating (US$), January’2021
Figure 8-28: Donepzil – Price of 30 Tablets of 10 mg Drug Disintegrating (US$), January’2021
Figure 8-29: Donepzil – Recommended & Incremented Dose for Alzheimer’s Disease (mg/day)
Figure 8-30: Donepzil – Time Interval for 1st & 2nd Dose Increment (Weeks)
Figure 8-31: Rivastigmine – Price of 60 Oral Capsules of Dosage 1.5 mg (US$), January’2021
Figure 8-32: Rivastigmine – Price of 100 (10X10) Oral Capsules of Dosage 1.5 mg (US$), January’2021
Figure 8-33: Rivastigmine – Price of 500 Oral Capsules of Dosage 1.5 mg (US$), January’2021
Figure 8-34: Rivastigmine – Price of 60 Oral Capsules of Dosage 3 mg (US$), January’2021
Figure 8-35: Rivastigmine – Price of 100 (10x10) Oral Capsules of Dosage 3 mg (US$), January’2021
Figure 8-36: Rivastigmine – Price of 500 Oral Capsules of Dosage 3 mg (US$), January’2021
Figure 8-37: Rivastigmine – Price of 60 Oral Capsules of Dosage 4.5 mg (US$), January’2021
Figure 8-38: Rivastigmine – Price of 100 Oral Capsules of Dosage 4.5 mg (US$), Janaury’2021
Figure 8-39: Rivastigmine – Price of 500 Oral Capsules of Dosage 4.5 mg (US$), January’2021
Figure 8-40: Rivastigmine – Price of 60 Oral Capsules of Dosage 6 mg (US$), January’2021
Figure 8-41: Rivastigmine – Price of 60 Oral Capsules of Dosage 6 mg (US$), January’2021
Figure 8-42: Rivastigmine – Price of 100 (10X10 each) Oral Capsules of Dosage 6 mg (US$), January’2021
Figure 8-43: Rivastigmine – Price of 500 Oral Capsules of Dosage 6 mg (US$), January’2021
Figure 8-44: Rivastigmine Oral – Recommended Initial & Incremented Dose (mg/day)
Figure 8-45: Rivastigmine Patch– Recommended Initial & Incremented Dose (mg/24 Hours)
Figure 8-46: Memantine – Price of 30 Capsules of Dosage 7 mg (US$), January’2021
Figure 8-47: Memantine – Price of 100 Capsules of Dosage 7 mg (US$), January’2021
Figure 8-48: Memantine – Price of 30 Capsules of Dosage 14 mg (US$), January’2021
Figure 8-49: Memantine – Price of 90 Capsules of Dosage 14 mg (US$), January’2021
Figure 8-50: Memantine – Price of 100 Capsules of Dosage 14 mg (US$), January’2021
Figure 8-51: Memantine – Price of 30 Capsules of Dosage 21 mg (US$), January’2021
Figure 8-52: Memantine – Price of 100 Capsules of Dosage 21 mg (US$), January’2021
Figure 8-53: Memantine – Price of 30 Capsules of Dosage 28 mg (US$), January’2021
Figure 8-54: Memantine – Price of Oral Kit for 49 (US$), January’2021
Figure 8-55: Memantine - Price of 200 ml (40 X 5 ml) of Oral Solution of Dosage 2 mg/ml (US$), January’2021
Figure 8-56: Memantine - Price of 240 ml of Oral Solution of Dosage 2 mg/ml (US$), January’2021
Figure 8-57: Memantine - Price of 360 ml of Oral Solution of Dosage 2 mg/ml (US$), January’2021
Figure 8-58: Memantine - Price of 50 Oral Tablets of Dosage 5 mg (US$), January’2021
Figure 8-59: Memantine - Price of 30 Oral Tablets of Dosage 10 mg (US$), January’2021
Figure 8-60: Memantine Tablet – Recommended Initial & Incremented Dose (mg/day)
Figure 8-61: Memantine XR – Recommended Initial & Incremented Dose (mg/day)
Figure 8-62: Ergoloid Mesylates – Average Price of 100 Tablets & Price per unit Tablet (US$), January’2021
Figure 8-63: Ergoloid Mesylates – Average Price of 10 Tablets & Price per unit Tablet (US$), January’2021
Figure 8-64: Ergoloid Mesylates – Daily, Monthly & Annual Treatment Cost (US$), January’2021
Figure 9-1: US - Number of Alzheimer's Drugs in Clinical Trials by Biomarker, 2021 till 2026
Figure 9-2: US - Number of Alzheimer's Drugs in Clinical Trials by Formulation, 2021 till 2026
Figure 9-3: US - Number of Alzheimer's Drugs in Clinical Trials by Organization, 2021 till 2026
Figure 9-4: US - Number of Alzheimer's Drugs in Clinical Trials by Phase, 2021 till 2026
Figure 9-5: US - Number of Alzheimer's Drugs in Clinical Trials by Patient Segment, 2021 till 2026
Figure 12-1: US Alzheimer's Drug Market Favourable Parameters
Figure 12-2: US - Alzheimer's DrugMarket Challenges
Figure 13-1: US – Alzheimer Disease Affected Individuals (Million), 2020, 2025 & 2050
Figure 13-2: US – Alzheimer Disease Patients (Million) by gender, 2020
