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Venous Leg Ulcers (Crural ulcer) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

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    Report

  • 60 Pages
  • February 2022
  • Region: Global
  • Global Markets Direct
  • ID: 5553768
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This pipeline guide Venous Leg Ulcers (Crural ulcer) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update, provides an overview of the Venous Leg Ulcers (Crural Ulcer) (Dermatology) pipeline landscape.

Venous leg ulcers develop when persistently high blood pressure in the veins of the legs (venous hypertension) causes damage to the skin, which eventually breaks down and forms an ulcer. Symptoms include swollen ankles filled with fluid that temporarily hold the imprint of finger when pressed (known as pitting edema), discoloration and darkening of skin around the ulcer (known as hemosiderosis), hardened skin around the ulcer, which may make leg feel hard and resemble the shape of an upside-down champagne bottle (known as lipodermatosclerosis), small, smooth areas of white skin, which may have tiny red spots (known as atrophie blanche).

Report Highlights


This pipeline guide Venous Leg Ulcers (Crural ulcer) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update, provides comprehensive information on the therapeutics under development for Venous Leg Ulcers (Crural Ulcer) (Dermatology), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Venous Leg Ulcers (Crural Ulcer) (Dermatology) pipeline guide also reviews of key players involved in therapeutic development for Venous Leg Ulcers (Crural Ulcer) and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase III, Phase II, IND/CTA Filed, Preclinical and Unknown stages are 1, 10, 2, 4 and 1 respectively.

Venous Leg Ulcers (Crural Ulcer) (Dermatology) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope


  • The pipeline guide provides a snapshot of the global therapeutic landscape of Venous Leg Ulcers (Crural Ulcer) (Dermatology).
  • The pipeline guide reviews pipeline therapeutics for Venous Leg Ulcers (Crural Ulcer) (Dermatology) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Venous Leg Ulcers (Crural Ulcer) (Dermatology) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Venous Leg Ulcers (Crural Ulcer) (Dermatology) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Venous Leg Ulcers (Crural Ulcer) (Dermatology)

Reasons to Buy


  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Venous Leg Ulcers (Crural Ulcer) (Dermatology).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Venous Leg Ulcers (Crural Ulcer) (Dermatology) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.

Table of Contents

IntroductionReport CoverageOverview
Therapeutics Development
  • Pipeline Overview
  • Pipeline by Companies
  • Products under Development by Companies

Therapeutics Assessment
  • Assessment by Target
  • Assessment by Mechanism of Action
  • Assessment by Route of Administration
  • Assessment by Molecule Type

Companies Involved in Therapeutics Development
  • Aurealis Therapeutics AG
  • CytoTools AG
  • Energenesis Biomedical Co Ltd
  • GangaGen Biotechnologies Pvt Ltd
  • Hypo-Stream Ltd
  • Mallinckrodt Plc
  • MediWound Ltd
  • NovaLead Pharma Pvt Ltd
  • Promore Pharma AB
  • QBiotics Group Ltd
  • Reponex Pharmaceuticals AS
  • RHEACELL GmbH & Co KG
  • Tissue Repair Pty Ltd
  • Venturis Therapeutics Inc
  • Zhittya Genesis Medicine Inc

Drug Profiles
  • Amesanar - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • AUP-16 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • Cell Therapy to Activate VEGF for Venous Leg Ulcers and Diabetic Foot Ulcers - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • CVBT-141 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • CVBT-141B - Drug Profile
  • Product Description
  • Mechanism Of Action
  • diperoxochloric acid - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • EBC-1013 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • ENERGIF-703 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • EscharEx - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • EscharEx Second Generation - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • FGF-1 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • molgramostim - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • NLP-328 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • P-128 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • ropocamptide - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • sodium hypochlorite - Drug Profile
  • Product Description
  • Mechanism Of Action
  • Stem Cell Therapy for Venous Leg Ulcers - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • TR-987 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events

Dormant ProjectsDiscontinued ProductsProduct Development Milestones
Featured News & Press Releases
  • Jan 24, 2022: MediWound announces positive topline results from its U.S. phase 2 trial of EscharEx for debridement of chronic wounds
  • Oct 25, 2021: Promore Pharma announces that scientific article has been published on clinical study results with ropocamptide for venous leg ulcers
  • Oct 19, 2021: From chronic to curable RHEACELL is developing a novel cell-therapy agent for the treatment of chronic venous ulcers
  • Jul 28, 2021: MediWound announces positive outcome of interim assessment for its EscharEx U.S. phase 2 adaptive design study
  • Jul 09, 2021: MediWound announces peer-reviewed paper detailing Escharex phase 2 randomized control trial results published in the online Wound Repair and Regeneration Journal
  • Jun 09, 2021: MediWound completes patient enrollment for interim assessment of its U.S. EscharEx phase 2 adaptive design study
  • Apr 22, 2021: MediWound enrolls first patient in phase 2 pharmacology study of EscharEx
  • Jan 11, 2021: MediWound provides progress update on its EscharEx clinical development program
  • Nov 20, 2020: Clarification of outcome in the clinical trial HEAL LL-37
  • Nov 19, 2020: Promore Pharma announces positive results from Phase IIb study of ropocamptide in the treatment of venous leg ulcers
  • Oct 08, 2020: The IND application of ENERGI-F703 for treating venous leg ulcers (VLU) has been approved by TFDA
  • Jul 14, 2020: Promore Pharma is granted a patent for ropocamptide in the US
  • Mar 24, 2020: Promore Pharma reached the targeted number of patients completing treatment in the HEAL LL-37 Phase IIb clinical trial
  • Dec 10, 2019: Promore Pharma has finalized recruitment of patients in HEAL LL-37 early
  • Dec 03, 2019: MediWound Initiates U.S. Phase 2 Adaptive design study of EscharEx for treatment of Venous Leg Ulcers

Appendix
  • Methodology
  • Coverage
  • Secondary Research
  • Primary Research
  • Expert Panel Validation
  • Contact the Analyst
  • Disclaimer

List of Tables
  • Number of Products under Development for Venous Leg Ulcers (Crural Ulcer), 2022
  • Number of Products under Development by Companies, 2022
  • Products under Development by Companies, 2022
  • Number of Products by Stage and Target, 2022
  • Number of Products by Stage and Mechanism of Action, 2022
  • Number of Products by Stage and Route of Administration, 2022
  • Number of Products by Stage and Molecule Type, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by Aurealis Therapeutics AG, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by CytoTools AG, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by Energenesis Biomedical Co Ltd, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by GangaGen Biotechnologies Pvt Ltd, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by Hypo-Stream Ltd, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by Mallinckrodt Plc, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by MediWound Ltd, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by NovaLead Pharma Pvt Ltd, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by Promore Pharma AB, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by QBiotics Group Ltd, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by Reponex Pharmaceuticals AS, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by RHEACELL GmbH & Co KG, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by Tissue Repair Pty Ltd, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by Venturis Therapeutics Inc, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Pipeline by Zhittya Genesis Medicine Inc, 2022
  • Venous Leg Ulcers (Crural Ulcer) - Dormant Projects, 2022

Venous Leg Ulcers (Crural Ulcer) - Discontinued Products
, 2022
List of Figures
  • Number of Products under Development for Venous Leg Ulcers (Crural Ulcer), 2022
  • Number of Products under Development by Companies, 2022
  • Number of Products by Targets, 2022
  • Number of Products by Stage and Targets, 2022
  • Number of Products by Mechanism of Actions, 2022
  • Number of Products by Stage and Mechanism of Actions, 2022
  • Number of Products by Routes of Administration, 2022
  • Number of Products by Stage and Routes of Administration, 2022
  • Number of Products by Molecule Types, 2022
  • Number of Products by Stage and Molecule Types, 2022

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Aurealis Therapeutics AG
  • CytoTools AG
  • Energenesis Biomedical Co Ltd
  • GangaGen Biotechnologies Pvt Ltd
  • Hypo-Stream Ltd
  • Mallinckrodt Plc
  • MediWound Ltd
  • NovaLead Pharma Pvt Ltd
  • Promore Pharma AB
  • QBiotics Group Ltd
  • Reponex Pharmaceuticals AS
  • RHEACELL GmbH & Co KG
  • Tissue Repair Pty Ltd
  • Venturis Therapeutics Inc
  • Zhittya Genesis Medicine Inc