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Bromodomain Containing Protein 2 - Drugs In Development, 2021

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    Drug Pipelines

  • 82 Pages
  • June 2021
  • Region: Global
  • Global Markets Direct
  • ID: 5359583
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According to the recently published report 'Bromodomain Containing Protein 2 - Drugs In Development, 2021'; Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) pipeline Target constitutes close to 11 molecules. Out of which approximately 10 molecules are developed by companies and remaining by the universities/institutes.

Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) - Bromodomain-containing protein 2 is a protein that is encoded by the BRD2 gene. It plays a role in spermatogenesis. It plays a role in the regulation of transcription, probably by chromatin remodeling and plays a role in nucleosome assembly. It regulates transcription of the CCND1 gene.

The report 'Bromodomain Containing Protein 2 - Drugs In Development, 2021' outlays comprehensive information on the Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type; that are being developed by Companies/Universities.

It also reviews key players involved in Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) targeted therapeutics development with respective active and dormant or discontinued projects. Currently, The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical and Discovery stages are 1, 2, 4, 2 and 1 respectively. Similarly, the universities portfolio in Preclinical stages comprises 1 molecules, respectively. Report covers products from therapy areas Oncology, Dermatology, Immunology and Musculoskeletal Disorders which include indications Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia), Diffuse Large B-Cell Lymphoma, Solid Tumor, Atopic Dermatitis (Atopic Eczema), Colorectal Cancer, Melanoma, Metastatic Hormone Refractory (Castration Resistant, Androgen-Independent) Prostate Cancer, Myelodysplastic Syndrome, Myelofibrosis, Non-Hodgkin Lymphoma, Ovarian Cancer, Post-Essential Thrombocythemia Myelofibrosis (Post-ET MF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), Small-Cell Lung Cancer, Triple-Negative Breast Cancer (TNBC), B-Cell Non-Hodgkin Lymphoma, Basal Cell Carcinoma (Basal Cell Epithelioma), Colon Cancer, Epithelial Ovarian Cancer, Fibrosis, Follicular Lymphoma, Inflammation, Leukemia, Lung Cancer, Lymphoma, Multiple Myeloma (Kahler Disease), Myeloproliferative Disorders, Non-Small Cell Lung Cancer, NUT Midline Carcinoma (NMC or Nuclear Protein in Testis Midline Carcinoma), Pancreatic Cancer, Plaque Psoriasis (Psoriasis Vulgaris), Primary Mediastinal B-Cell Lymphoma, Psoriasis, Refractory Acute Myeloid Leukemia, Relapsed Acute Myeloid Leukemia, Rheumatoid Arthritis, Systemic Sclerosis (Scleroderma), Unspecified B-Cell Lymphomas and Vitiligo.

Note: Certain content/sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope


  • The report provides a snapshot of the global therapeutic landscape for Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2)
  • The report reviews Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
  • The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
  • The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
  • The report reviews key players involved in Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) targeted therapeutics and enlists all their major and minor projects
  • The report assesses Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
  • The report summarizes all the dormant and discontinued pipeline projects
  • The report reviews latest news and deals related to Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) targeted therapeutics

Reasons to Buy


  • Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
  • Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
  • Identify and understand the targeted therapy areas and indications for Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2)Identify the use of drugs for target identification and drug repurposing
  • Identify potential new clients or partners in the target demographic
  • Develop strategic initiatives by understanding the focus areas of leading companies
  • Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
  • Devise corrective measures for pipeline projects by understanding Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) development landscape
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Table of Contents

Introduction
  • Report Coverage

Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) - Overview
Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) - Therapeutics Development
  • Products under Development by Stage of Development
  • Products under Development by Therapy Area
  • Products under Development by Indication
  • Products under Development by Companies
  • Products under Development by Universities/Institutes

Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) - Therapeutics Assessment
  • Assessment by Mechanism of Action
  • Assessment by Route of Administration
  • Assessment by Molecule Type

Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) - Companies Involved in Therapeutics Development
  • AbbVie Inc
  • Amgen Inc
  • Boehringer Ingelheim International GmbH
  • Boston Pharmaceuticals Inc
  • Bristol-Myers Squibb Co
  • Constellation Pharmaceuticals Inc
  • In4Derm Ltd
  • Ningbo Wenda Pharmaceutical Technology Co Ltd
  • Zenith Epigenetics Ltd

Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) - Drug Profiles
ABBV-744 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

BI-894999 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

BOS-475 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

CC-95775 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

NHWD-870 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

NUE-19796 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

NUE-20798 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

pelabresib - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

QCA-570 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Small Molecules to Inhibit BRD2 for Inflammation - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

ZEN-3694 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Bromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) - Dormant ProductsBromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) - Discontinued ProductsBromodomain Containing Protein 2 (Really Interesting New Gene 3 Protein or O27.1.1 or BRD2) - Product Development Milestones
Featured News & Press Releases
  • Jun 11, 2021: Constellation Pharmaceuticals provides an update from the ongoing MANIFEST study of Pelabresib
  • Jun 11, 2021: Constellation Pharmaceuticals provides an update from the Ongoing MANIFEST study of Pelabresib
  • Mar 15, 2021: Zenith Epigenetics announces dosing of first mCRPC patient with a combination of ZEN-3694 + Merck’s immune check point inhibitor KEYTRUDA
  • Jan 07, 2021: Constellation Pharmaceuticals appoints Brendan Delaney as Chief Commercial Officer
  • Dec 06, 2020: Constellation Pharmaceuticals provides update of MANIFEST study for CPI-0610 at ASH Meeting
  • Nov 23, 2020: Constellation Pharmaceuticals to host analyst / investor event to discuss update of MANIFEST clinical trial for CPI-0610 presented at ASH Meeting
  • Jul 29, 2020: Zenith Epigenetics advances ZEN-3694 in multiple cancer programs
  • Jul 29, 2020: Researchers optimistic after dose-determining trial of compound against metastatic castration-resistant prostate cancer
  • Jun 12, 2020: Constellation Pharmaceuticals provides updates of MANIFEST study for CPI-0610 and EZH2 Franchise
  • May 28, 2020: Constellation Pharmaceuticals to host analyst/investor event to discuss update of MANIFEST clinical trial for CPI-0610
  • May 28, 2020: Constellation Pharmaceuticals to host analyst / investor event to discuss update of MANIFEST clinical trial for CPI-0610
  • May 14, 2020: Constellation Pharmaceuticals provides update of preliminary data for CPI-0610 in three EHA Abstracts
  • Apr 15, 2020: New cancer drug shrinks tumors, reduces side effects, in animal studies
  • Jan 07, 2020: Zenith Epigenetics receives US$5 million milestone payment from Newsoara
  • Dec 19, 2019: Zenith Epigenetics announces clinical advancement of ZEN-3694

Appendix
  • Methodology
  • Coverage
  • Secondary Research
  • Primary Research
  • Expert Panel Validation
  • Contact the Publisher
  • Disclaimer

List of Tables
  • Number of Products under Development by Stage of Development, 2021
  • Number of Products under Development by Therapy Areas, 2021
  • Number of Products under Development by Indications, 2021
  • Number of Products under Development by Companies, 2021
  • Products under Development by Companies, 2021
  • Number of Products under Investigation by Universities/Institutes, 2021
  • Products under Investigation by Universities/Institutes, 2021
  • Number of Products by Stage and Mechanism of Actions, 2021
  • Number of Products by Stage and Route of Administration, 2021
  • Number of Products by Stage and Molecule Type, 2021
  • Pipeline by AbbVie Inc, 2021
  • Pipeline by Amgen Inc, 2021
  • Pipeline by Boehringer Ingelheim International GmbH, 2021
  • Pipeline by Boston Pharmaceuticals Inc, 2021
  • Pipeline by Bristol-Myers Squibb Co, 2021
  • Pipeline by Constellation Pharmaceuticals Inc, 2021
  • Pipeline by In4Derm Ltd, 2021
  • Pipeline by Ningbo Wenda Pharmaceutical Technology Co Ltd, 2021
  • Pipeline by Zenith Epigenetics Ltd, 2021
  • Dormant Products, 2021
  • Discontinued Products, 2021

List of Figures
  • Number of Products under Development by Stage of Development, 2021
  • Number of Products under Development by Therapy Areas, 2021
  • Number of Products under Development by Top 10 Indications, 2021
  • Number of Products by Stage and Mechanism of Actions, 2021
  • Number of Products by Routes of Administration, 2021
  • Number of Products by Stage and Routes of Administration, 2021
  • Number of Products by Stage and Molecule Type, 2021

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • AbbVie Inc
  • Amgen Inc
  • Boehringer Ingelheim International GmbH
  • Boston Pharmaceuticals Inc
  • Bristol-Myers Squibb Co
  • Constellation Pharmaceuticals Inc
  • In4Derm Ltd
  • Ningbo Wenda Pharmaceutical Technology Co Ltd
  • Zenith Epigenetics Ltd