Handbook of Pharmaceutical Additives-Third Ed.

  • ID: 560867
  • Book
  • 1200 Pages
  • Synapse Information Resources, Inc
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The Handbook of Pharmaceutical Additives, Third Edition has been extensively updated from the previous edition, which was published in 2002. It describes more than 5300 trade name products and 4000 generic chemicals and materials, available from worldwide manufacturers, that function as pharmaceutical additives.
Pharmaceutical additives are defined in this reference as secondary ingredients present in both prescription and over-the-counter drug formulations and contributing in one or more of the following ways:

- improving consumption ease of the dosage form by masking unpleasant odor, improving palatibility or appearance of the active ingredient.
- enabling or enhancing the delivery of the drug or medicine that is available in a variety of dosage forms (i.e., oral; topical, ophthalmic, and otic; suppositories; injectables; inhalants) and thus improving its efficacy, control of bioavailability, uniformity, and/or flow characteristics
- increasing the stability of active ingredients
- acting as a filler or diluent so that an adequate amount of material is available to properly fill a dosage form
- acting as an antimicrobial or antioxidant to extend the shelf life of the active ingredient

Thus, the definition of pharmaceutical additives for the purpose of this work encompasses excipients, synergists, or chemicals that substantively contribute to the effectiveness of the active ingredient. Entries for both trade names and chemicals contain extensive information gathered from worldwide manufacturers, distributors, trade journals, government documents, and other reference sources.

Both the Handbook of Pharmaceutical Additives, Third Edition and the software version centralize and integrate information on these chemicals and materials thereby serving as an essential guide to product managers, formulation scientists, quality controllers, ingredient chemists, pharmacists, physicians, and consumers.
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Book and Software:

PART I-Trade Name Reference
Trade Name Reference contains over 5300 alphabetical entries of trade name pharmaceutical additive products with extensive profiles of each product listed.
Software features: Full-text Search with Boolean operator support

Keyword Indexes: Comprehensive Index, Trade Name X-Ref, Generic Chemical X-Ref, Manufacturers X-Ref, CAS X-Ref, EINECS/ELINCS X-Ref, Functional/Applications X-Ref.

Hyperlinking: Trade names manufacturers to Manufacturers Directory and websites; Generic chemicals to Generic Products, Trade Name Cross-Reference

Part II-Chemical Component Cross-Reference
Chemical Component Cross-Reference contains more than 4000 pharmaceutical chemicals/materials that are either contained in the trade name products profiled in Part I or are generic chemicals used as pharmaceutical additive ingredients. Each entry includes, wherever possible, its synonyms, CAS number, EINECS number/ELINCS, FEMA number, UN/DOT number, molecular and empirical formulas, chemical properties, functions and applications, toxicology, precautions, use levels, regulatory information, and manufacturers and distributors of the chemical. All chemical/material synonyms are cross-referenced back to the main entry. The chemical monograph entries also contain a listing of the trade name products that are either equivalent to the chemical entry or contain this chemical as one of its ingredients.

Software features: Full-text Search with Boolean operator support
Keyword Indexes: Comprehensive Index, Trade Name X-Ref, Generic Chemical X-Ref, Manufacturers X-Ref, CAS X-Ref, EINECS/ELINCS X-Ref, Functional/Applications X-Ref., Molecular Formula Dir.

Hyperlinking: Trade names to Trade Name Reference, generic manufacturers to Manufacturers Directory, all cross-references (synonyms) to main entries

Part III-Functional/Application Index
Functional/Application Index is a powerful tool for locating the trade names and chemicals based on their function and application. By searching for key functional words related to pharmaceutical additives such as anticaking agents, binders, colorants, disintegrants, emulsifiers, encapsulants, fillers, flavors, gellants, in specific application areas such as tablets, capsules, inhalants, ointments, suppositories, etc., the user is directed to the trade names and/or chemicals that have that specific functional/application attribute. The generic component names are distinguished from the trade names by italic type in the book and color in the software.

Software features: Full-text Search with Boolean operator support

Hyperlinking: Trade names to Trade name Section, Generics to Generic Chemical section
Part IV-Manufacturers Directory
Detailed contact information for the more than 3000 worldwide manufacturers and their branches of trade name products and chemical components that are referenced in this handbook. Wherever possible, telephone, telefax, toll-free numbers, e-mail and internet addresses (functional in the software), and complete mailing addresses are included for each manufacturer.

Software features: Full-text Search with Boolean operator support
Keyword Indexes: Comprehensive Index, Manufacturers Dir., Manufacturers X-Ref., MFG Web&Email Directory
Hyperlinking: All cross-references (alternate names) to main entries, Manufacturer Web sites, Manufacturer Email
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