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3D Protein Structure Analysis Market - A Global and Country Analysis: Focus on Product, End User, and Region - Analysis and Forecast, 2022-2032

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    Report

  • 157 Pages
  • September 2022
  • Region: Global
  • BIS Research
  • ID: 5659601
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Increase in R&D Expenditure in Drug Discovery and Development

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In 2021, the global 3D protein structure analysis market was valued at $1,017.2 million, and it is expected to reach $2,676.6 million by 2032, growing at a CAGR of 9.32% during the forecast period 2022-2032. The growth in the global 3D protein structure analysis market is expected to be driven by technological advancements in equipment for protein structure analysis and by an increase in R&D expenditure to accelerate protein structure analysis.

Market Lifecycle Stage

One of the main goals of molecular biology research is to understand protein structure. Protein complex analysis involves a complete evaluation of the structure and function of proteins because proteins are found in intricate biological samples. The structure of protein complexes can be discovered using contemporary protein complex analysis methods. At present cryo-electron microscopy (EM), small angle X-Ray scattering (SAXS), nuclear magnetic resonance (NMR) spectroscopy, and X-Ray crystallography are used extensively in efforts to describe and understand molecular structures and molecular recognition mechanisms. Leading manufacturers like Bruker Corporation, JEOL Ltd., and Spectris plc provide equipment for 3D protein structure analysis according to one’s needs. These equipment can address the laboratory’s throughput needs.

Impact

  • The presence of major equipment providers of 3D protein structure analysis has a major impact on the market. For instance, in April 2022, NJ Biopharmaceuticals LLC and JEOL Ltd. announced their collaboration to bring innovative drug discovery platform solutions using JEOL's 800 MHz NMR. With the help of this partnership, JEOL Ltd. aspires to grow its 3D protein structure analysis base and increase its existing product line.
  • In August 2020, Thermo Fisher Scientific Inc., a global leader in providing scientific services, announced that it would facilitate access to cryo-electron microscopy (cryo-EM) by connecting pharmaceutical and biotechnology companies with contract research organizations (CROs) that provide start-up packages for this game-changing technology as a service.

Market Segmentation

Segmentation 1: by Product

  • Consumable
  • Equipment
  • Computational Software

Based on product, the global 3D protein structure analysis market is expected to be dominated by the consumable segment. This is due to the availability of several reagents, kits, screens, solvents, detergents, and others to be used in different technologies for 3D protein structure analysis.

Segmentation 2: by End User

  • Biopharmaceutical Company
  • Academic and Research Institute
  • Other End User

Based on end users, the biopharmaceutical company segment is the dominating end user in the market. The expanding application of protein structure analysis in a variety of industries, primarily in pharmaceutical companies for drug development, is further expected to contribute to its growing trend.

Segmentation 3: by Region

  • North America
  • Europe
  • Asia-Pacific
  • Rest-of-the-World

North America dominated the global market with a revenue of $395.5 million in 2021. However, the Asia-Pacific (APAC) region, constituting several emerging economies, is expected to register the highest CAGR of 10.33% during the forecast period 2022-2032.

Recent Developments in Global 3D Protein Structure Analysis Market

  • In February 2022, JEOL Ltd. announced the development of a new cold field emission cryo-electron microscope (cryo-EM), the CRYO ARM 200 II (JEM-Z200CA), dedicated to single particle analysis of proteins.
  • In November 2021, JEOL Ltd. announced the availability of ""ECZ Luminous"" nuclear magnetic resonance console (JNM-ECZL series). This product is the next step in spectrometer miniaturization and extended performance through state-of-the-art digital and high-frequency technologies.
  • In October 2020, Thermo Fisher Scientific Inc. introduced two ground-breaking imaging filters, i.e., the Thermo Scientific Selectris Imaging Filter and the Thermo Scientific Selectris X Imaging Filter, which elevated cryo-electron microscopy (cryo-EM) to a new level by allowing users to view proteins at true atomic resolution.
  • In April 2021, Thermo Fisher Scientific Inc. unveiled the Thermo Scientific E-CFEG, a significant accessory for the Thermo Scientific Krios Cryo-TEM and the company's new cold field emission gun. In comparison to other commercially available technologies, the E-four CFEG's key components work together to achieve single particle analysis (SPA) resolution levels that are unprecedented.

Demand - Drivers and Limitations

Following are the demand drivers for the global 3D protein structure analysis market:

  • Technological Advancements in Equipment for Protein Structure Analysis
  • Increase in R&D Expenditure in Drug Discovery and Development
  • Rising Focus on Automation and Miniaturization in X-Ray Crystallography Workflow

The market is expected to face some limitations too due to the following challenges:

  • Certain Instrument Limitations Pertaining to 3D Protein Structure Analysis
  • Lack of Qualified Personnel
  • High Cost and Time-Consuming Method

How can this report add value to an organization?

Product/Innovation Strategy: The report considers consumable, equipment, and computational software-based companies. Most companies provide consumables that are compatible with equipment for 3D protein structure analysis.

Growth/Marketing Strategy: The key components in 3D protein structure analysis are the equipment, consumable, and computational software. The main market revenue is generated from the consumable segment. The entire workflow has been well explained in the report, along with pricing analysis considering the key companies involved in the production.

Competitive Strategy: The key players in the global 3D protein structure analysis market have been analyzed and profiled in the study, consisting of consumable, equipment, and computational software-based companies. Moreover, a detailed competitive benchmarking of the players operating in the global 3D protein structure analysis market has been done to help the reader understand how players stack against each other, presenting a clear market landscape. Additionally, comprehensive competitive strategies such as partnerships, agreements, and collaborations will aid the reader in understanding the untapped revenue pockets in the market.

Key Market Players and Competition Synopsis

The companies that are profiled have been selected based on inputs gathered from primary experts, analyzing company coverage, product portfolio, and market penetration.

Some of the prominent names established in this market are:

  • Bruker Corporation
  • JEOL Ltd.
  • Spectris plc
  • Thermo Fisher Scientific Inc.
  • Merck KGaA
  • Schrodinger, Inc.
  • Molecular Dimensions
  • Arinax Scientific Instrumentation.
  • Cambridge Isotope Laboratories, Inc.
  • HAMPTON RESEARCH CORP.
  • DNASTAR
  • RosettaCommons.org
  • Rigaku Corporation
  • Dassault Systemes
  • Jena Bioscience GmbH

Table of Contents

1 Market
1.1 Product Definition
1.2 Inclusion and Exclusion
1.3 Scope of Work
1.4 Key Questions Answered in the Report

2 Research Methodology
2.1 Global 3D Protein Structure Analysis Market: Research Methodology
2.2 Primary Data Sources
2.3 Secondary Data Sources
2.4 Market Estimation Model
2.5 Criteria for Company Profiling

3 Market Overview
3.1 Market Introduction
3.2 Top Technologies in the Global Protein 3D Structure Analysis Market
3.3 Current Market Size and Future Growth Potential, $Million, 2021-2032

4 Market Dynamics
4.1 Overview
4.1.1 Market Drivers
4.1.1.1 Technological Advancements in Equipment for Protein Structure Analysis
4.1.1.2 Increase in R&D Expenditure in Drug Discovery and Development
4.1.1.3 Rising Focus on Automation and Miniaturization in X-Ray Crystallography Workflow
4.1.2 Market Restraints
4.1.2.1 Certain Instrument Limitations Pertaining to 3D Protein Structure Analysis
4.1.2.2 Lack of Qualified Personnel
4.1.2.3 High Cost and Time-Consuming Method
4.1.3 Market Opportunities
4.1.3.1 Increasing Use of Small Angle X-Ray Scattering (SAXS) Technique for 3D Protein Structure Analysis
4.1.3.2 Surging Collaborations Between Major Key Players to Enhance their Market Presence

5 Competitive Landscape
5.1 Overview
5.2 Partnership and Collaboration Activities
5.3 Product Launches and Expansions
5.4 Other Developments
5.5 Market Share Analysis, 2020-2021
5.6 Growth-Share Analysis
5.6.1 Growth-Share Analysis (by Company)
5.6.2 Growth-Share Analysis (by Product)
5.6.3 Growth-Share Analysis (by End User)

6 Global 3D Protein Structure Analysis Market (by Product)
6.1 Overview
6.2 Consumable
6.2.1 X-Ray Crystallography
6.2.2 Nuclear Magnetic Resonance (NMR) Spectroscopy
6.2.3 Cryo-Electron Microscopy (Cryo-EM)
6.2.4 Small Angle X-Ray Scattering (SAXS)
6.3 Equipment
6.3.1 X-Ray Crystallography
6.3.2 Nuclear Magnetic Resonance (NMR) Spectroscopy
6.3.3 Cryo-Electron Microscopy (Cryo-EM)
6.3.4 Small Angle X-Ray Scattering (SAXS)
6.4 Computational Software

7 Global Protein 3D Structure Analysis Market (by End User)
7.1 Overview
7.1.1 Biopharmaceutical Company
7.1.2 Academic and Research Institute
7.1.3 Other End User

8 Global 3D Protein Structure Analysis Market (by Region)
8.1 Overview
8.2 North America
8.2.1 U.S.
8.2.2 Canada
8.3 Europe
8.3.1 Germany
8.3.2 U.K.
8.3.3 France
8.3.4 Italy
8.3.5 Spain
8.3.6 Rest-of-Europe
8.4 Asia-Pacific
8.4.1 China
8.4.2 Japan
8.4.3 India
8.4.4 South Korea
8.4.5 Australia
8.4.6 Rest-of-Asia-Pacific
8.5 Rest-of-the-World

9 Company Profiles
9.1 Overview
9.2 Bruker Corporation
9.2.1 Company Overview
9.2.2 Role of Bruker Corporation in the Global 3D Protein Structure Analysis Market
9.2.3 Key Customers of the Company
9.2.4 Key Competitors of the Company
9.2.5 Financials
9.2.6 Key Insights about the Financial Health of the Company
9.2.7 Recent Developments
9.2.8 Analyst Perspective
9.3 JEOL Ltd.
9.3.1 Company Overview
9.3.2 Role of JEOL Ltd. in the Global 3D Protein Structure Analysis Market
9.3.3 Key Customers of the Company
9.3.4 Key Competitors of the Company
9.3.5 Financials
9.3.6 Key Insights about the Financial Health of the Company
9.3.7 Recent Developments
9.3.8 Analyst Perspective
9.4 Spectris plc
9.4.1 Company Overview
9.4.2 Role of Spectris plc in the Global 3D Protein Structure Analysis Market
9.4.3 Key Customers of the Company
9.4.4 Key Competitors of the Company
9.4.5 Financials
9.4.6 Key Insights about the Financial Health of the Company
9.4.7 Analyst Perspective
9.5 Thermo Fisher Scientific Inc.
9.5.1 Company Overview
9.5.2 Role of Thermo Fisher Scientific Inc. in the Global 3D Protein Structure Analysis Market
9.5.3 Key Customers of the Company
9.5.4 Key Competitors of the Company
9.5.5 Financials
9.5.6 Key Insights about the Financial Health of the Company
9.5.7 Recent Developments
9.5.8 Analyst Perspective
9.6 Merck KGaA
9.6.1 Company Overview
9.6.2 Role of Merck KGaA in the Global 3D Protein Structure Analysis Market
9.6.3 Key Customers of the Company
9.6.4 Key Competitors of the Company
9.6.5 Financials
9.6.6 Key Insights about the Financial Health of the Company
9.6.7 Analyst Perspective
9.7 Schrodinger, Inc.
9.7.1 Company Overview
9.7.2 Role of Schrodinger, Inc. in the Global 3D Protein Structure Analysis Market
9.7.3 Key Competitors of the Company
9.7.4 Financials
9.7.5 Key Insights about the Financial Health of the Company
9.7.6 Analyst Perspective
9.8 Molecular Dimensions
9.8.1 Company Overview
9.8.2 Role of Molecular Dimensions in the Global 3D Protein Structure Analysis Market
9.8.3 Key Competitors of the Company
9.8.4 Analyst Perspective
9.9 Arinax Scientific Instrumentation.
9.9.1 Company Overview
9.9.2 Role of Arinax Scientific Instrumentation. in the Global 3D Protein Structure Analysis Market
9.9.3 Key Competitors of the Company
9.9.4 Analyst Perspective
9.1 Cambridge Isotope Laboratories, Inc.
9.10.1 Company Overview
9.10.2 Role of Cambridge Isotope Laboratories, Inc. in the Global 3D Protein Structure Analysis Market
9.10.3 Key Customers of the Company
9.10.4 Key Competitors of the Company
9.10.5 Recent Development
9.10.6 Analyst Perspective
9.11 HAMPTON RESEARCH CORP.
9.11.1 Company Overview
9.11.2 Role of HAMPTON RESEARCH CORP. in the Global 3D Protein Structure Analysis Market
9.11.3 Key Competitors of the Company
9.11.4 Analyst Perspective
9.12 DNASTAR
9.12.1 Company Overview
9.12.2 Role of DNASTAR in the Global 3D Protein Structure Analysis Market
9.12.3 Key Customers of the Company
9.12.4 Key Competitors of the Company
9.12.5 Analyst Perspective
9.13 RosettaCommons.org
9.13.1 Company Overview
9.13.2 Role of RosettaCommons.org in the Global 3D Protein Structure Analysis Market
9.13.3 Key Competitors of the Company
9.13.4 Analyst Perspective
9.14 Rigaku Corporation
9.14.1 Company Overview
9.14.2 Role of Rigaku Corporation in the Global 3D Protein Structure Analysis Market
9.14.3 Key Competitors of the Company
9.14.4 Analyst Perspective
9.15 Dassault Systemes
9.15.1 Company Overview
9.15.2 Role of Dassault Systemes in the Global 3D Protein Structure Analysis Market
9.15.3 Key Competitors of the Company
9.15.4 Financials
9.15.5 Analyst Perspective
9.16 Jena Bioscience GmbH
9.16.1 Company Overview
9.16.2 Role of Jena Bioscience GmbH in the Global 3D Protein Structure Analysis Market
9.16.3 Key Competitors of the Company
9.16.4 Analyst Perspective

List of Figures
Figure 1: Impact Analysis of Drivers, Challenges, and Opportunities on the Global 3D Protein Structure Analysis Market
Figure 2: Global 3D Protein Structure Analysis Market (by Product), $Million, 2021 and 2032
Figure 3: Global 3D Protein Structure Analysis Market (by End User), $Million, 2021 and 2032
Figure 4: Global 3D Protein Structure Analysis Market Snapshot (by Region)
Figure 5: Global 3D Protein Structure Analysis Market Segments
Figure 6: Global 3D Protein Structure Analysis Market: Methodology
Figure 7: Primary Research Methodology
Figure 8: Top-Down Approach (Segment-Wise Analysis)
Figure 9: Primary Techniques for 3D Protein Structure Analysis
Figure 10: Global 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 11: Global 3D Protein Structure Analysis Market - Market Dynamics
Figure 12: Major Bruker’s High-Range NMR Spectrometers
Figure 13: Share of Key Developments and Strategies, January 2018-August 2022
Figure 14: Partnership and Collaboration Activities Share (by Company), January 2019-August 2022
Figure 15: Product Launches and Expansions Share (by Company), January 2018-August 2022
Figure 16: Market Share Analysis for Global 3D Protein Structure Analysis Market, 2020 and 2021
Figure 17: Growth-Share Analysis for Global 3D Protein Structure Analysis Market (by Company), 2020-2021
Figure 18: Growth-Share Analysis for Global 3D Protein Structure Analysis Market (by Product), 2021-2032
Figure 19: Growth-Share Analysis for Global 3D Protein Structure Analysis Market (by End User), 2021-2032
Figure 20: Global 3D Protein Structure Analysis Market (by Product)
Figure 21: Global 3D Protein Structure Analysis Market (by Product), $Million, 2021 and 2032
Figure 22: Global 3D Protein Structure Analysis Market (Consumable), $Million, 2021-2032
Figure 23: Global 3D Protein Structure Analysis Market (X-Ray Crystallography Consumable), $Million, 2021-2032
Figure 24: Global 3D Protein Structure Analysis Market (NMR Spectroscopy Consumable), $Million, 2021-2032
Figure 25: Global 3D Protein Structure Analysis Market (Cryo-EM Consumable), $Million, 2021-2032
Figure 26: Global 3D Protein Structure Analysis Market (SAXS), $Million, 2021-2032
Figure 27: Global 3D Protein Structure Analysis Market (Equipment), $Million, 2021-2032
Figure 28: Working of the X-Ray Crystallography Technique
Figure 29: X-Ray Crystallography: Advantages
Figure 30: Global 3D Protein Structure Analysis Market (X-Ray Crystallography Equipment), $Million, 2021-2032
Figure 31: NMR Spectroscopy: Advantages
Figure 32: Global 3D Protein Structure Analysis Market (NMR Spectroscopy Equipment), $Million, 2021-2032
Figure 33: Cryo-EM: Working
Figure 34: Global 3D Protein Structure Analysis Market (Cryo-EM Equipment), $Million, 2021-2032
Figure 35: Small Angle X-Ray Scattering (SAXS): Advantages
Figure 36: Global 3D Protein Structure Analysis Market (SAXS Equipment), $Million, 2021-2032
Figure 37: Global 3D Protein Structure Analysis Market (Computational Software), $Million, 2021-2032
Figure 38: List of Major Software Providers for 3D Protein Structure Analysis
Figure 39: Global 3D Protein Structure Analysis Market (by End User)
Figure 40: Global 3D Protein Structure Analysis Market (by End User), $Million, 2021 and 2032
Figure 41: Global 3D Protein Structure Analysis Market (Biopharmaceutical Company), $Million, 2021-2032
Figure 42: Global 3D Protein Structure Analysis Market (Academic and Research Institute), $Million, 2021-2032
Figure 43: Global 3D Protein Structure Analysis Market (Other End User), $Million, 2021-2032
Figure 44: Global 3D Protein Structure Analysis Market Snapshot (by Region)
Figure 45: Global 3D Protein Structure Analysis Market (by Region), $Million, 2021-2032
Figure 46: North America 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 47: North America: Market Dynamics
Figure 48: North America 3D Protein Structure Analysis Market (by Country), $Million, 2021 2032
Figure 49: U.S. 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 50: Canada 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 51: Europe 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 52: Europe: Market Dynamics
Figure 53: Europe 3D Protein Structure Analysis Market (by Country), $Million, 2021-2032
Figure 54: Germany 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 55: U.K. 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 56: France 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 57: Italy 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 58: Spain 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 59: Rest-of-Europe 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 60: Asia-Pacific 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 61: Asia-Pacific: Market Dynamics
Figure 62: Asia-Pacific 3D Protein Structure Analysis Market (by Country), $Million, 2021-2032
Figure 63: China 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 64: Japan 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 65: India 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 66: South Korea 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 67: Australia 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 68: Rest-of-Asia-Pacific 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 69: Rest-of-the-World 3D Protein Structure Analysis Market, $Million, 2021-2032
Figure 70: Total Number of Companies Profiled
Figure 71: Bruker Corporation: Product Portfolio
Figure 72: Bruker Corporation: Overall Financials, $Million, 2019-2021
Figure 73: Bruker Corporation: Revenue (by Segment), $Million, 2019-2021
Figure 74: Bruker Corporation: Revenue (by Region), $Million, 2019-2021
Figure 75: Bruker Corporation: R&D Expenditure, $Million, 2019-2021
Figure 76: JEOL Ltd.: Product Portfolio
Figure 77: JEOL Ltd.: Overall Financials, $Million, 2019-2021
Figure 78: JEOL Ltd.: Revenue (by Segment), $Million, 2019-2021
Figure 79: JEOL Ltd.: Revenue (by Region), $Million, 2019-2021
Figure 80: JEOL Ltd.: R&D Expenditure, $Million, 2019-2021
Figure 81: Spectris plc: Product Portfolio
Figure 82: Spectris plc: Overall Financials, $Million, 2019-2021
Figure 83: Spectris plc: Revenue (by Segment), $Million, 2019-2021
Figure 84: Spectris plc: Revenue (by Region), $Million, 2019-2021
Figure 85: Spectris plc: R&D Expenditure, $Million, 2019-2021
Figure 86: Thermo Fisher Scientific Inc.: Product Portfolio
Figure 87: Thermo Fisher Scientific Inc.: Overall Financials, $Million, 2019-2021
Figure 88: Thermo Fisher Scientific Inc.: Revenue (by Segment), $Million, 2019-2021
Figure 89: Thermo Fisher Scientific Inc.: Revenue (by Region), $Million, 2019-2021
Figure 90: Thermo Fisher Scientific Inc.: R&D Expenditure, $Million, 2019-2021
Figure 91: Merck KGaA: Product Portfolio
Figure 92: Merck KGaA: Overall Financials, $Million, 2019-2021
Figure 93: Merck KGaA: Revenue (by Segment), $Million, 2019-2021
Figure 94: Merck KGaA: Revenue (by Region), $Million, 2019-2021
Figure 95: Merck KGaA: R&D Expenditure, $Million, 2019-2021
Figure 96: Schrodinger, Inc.: Product Portfolio
Figure 97: Schrodinger, Inc.: Overall Financials, $Million, 2019-2021
Figure 98: Schrodinger, Inc.: Revenue (by Segment), $Million, 2019-2021
Figure 99: Schrodinger, Inc.: Revenue (by Region), $Million, 2019-2021
Figure 100: Schrodinger, Inc.: R&D Expenditure, $Million, 2019-2021
Figure 101: Molecular Dimensions: Product Portfolio
Figure 102: Arinax Scientific Instrumentation.: Product Portfolio
Figure 103: Cambridge Isotope Laboratories, Inc.: Product Portfolio
Figure 104: HAMPTON RESEARCH CORP.: Product Portfolio
Figure 105: DNASTAR: Product Portfolio
Figure 106: RosettaCommons.org: Product Portfolio
Figure 107: Rigaku Corporation: Product Portfolio
Figure 108: Dassault Systemes: Product Portfolio
Figure 109: Dassault Systemes: Overall Financials, $Million, 2019-2021
Figure 110: Dassault Systemes: Revenue (by Segment), $Million, 2019-2021
Figure 111: Dassault Systemes: Revenue (by Region), $Million, 2019-2021
Figure 112: Jena Bioscience GmbH: Product Portfolio

List of Tables
Table 1: Comparison of X-Ray Crystallography, Cryo-EM, and NMR Spectroscopy
Table 2: Global 3D Protein Structure Analysis Market: Consumables for X-Ray Crystallography
Table 3: Global 3D Protein Structure Analysis Market: Consumables for NMR Spectroscopy
Table 4: Global 3D Protein Structure Analysis Market: Consumables for Cryo-EM
Table 5: Key Players and their Products: X-Ray Crystallography Technique
Table 6: Key Players and their Products: NMR Spectroscopy Technique
Table 7: Key Players and their Products: Cryo-EM Technique
Table 8: Key Players and their Products: SAXS

Companies Mentioned

  • Bruker Corporation
  • JEOL Ltd.
  • Spectris plc
  • Thermo Fisher Scientific Inc.
  • Merck KGaA
  • Schrodinger, Inc.
  • Molecular Dimensions
  • Arinax Scientific Instrumentation.
  • Cambridge Isotope Laboratories, Inc.
  • HAMPTON RESEARCH CORP.
  • DNASTAR
  • RosettaCommons.org
  • Rigaku Corporation
  • Dassault Systemes
  • Jena Bioscience GmbH

Table Information