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Results for tag: "Lactulose"

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Constipation - Pipeline Review, H2 2019

  • Drug Pipelines
  • September 2019
  • 111 Pages
  • Global
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Lactulose is a type of gastrointestinal drug used to treat constipation and hepatic encephalopathy. It is a synthetic disaccharide composed of galactose and fructose molecules. It is a non-absorbable sugar that is metabolized by bacteria in the colon, resulting in the production of lactic acid and other short-chain fatty acids. This increases the osmotic pressure in the colon, which helps to soften the stool and increase its frequency. It is also used to reduce the levels of ammonia in the blood, which can be a symptom of hepatic encephalopathy. Lactulose is available in both liquid and tablet form, and is often prescribed in combination with other medications. It is generally well-tolerated, but can cause side effects such as flatulence, abdominal cramps, and diarrhea. Some companies in the lactulose market include AbbVie, Allergan, AstraZeneca, Bayer, GlaxoSmithKline, Merck, Novartis, Pfizer, and Sanofi. Show Less Read more