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Regulatory T Cells (Tregs) are a type of immune cell that play an important role in controlling the body's immune response. They are used in biotechnology to treat a variety of diseases, including autoimmune diseases, allergies, and cancer. Tregs can be used to suppress the immune system, allowing the body to tolerate foreign substances, such as transplanted organs, or to reduce inflammation. They can also be used to stimulate the immune system to fight cancer or other diseases.
Tregs are typically isolated from a patient's own blood or tissue, or from donor sources. They can then be modified to express specific proteins or receptors, or to produce cytokines, to enhance their therapeutic effects. Tregs can also be engineered to express chimeric antigen receptors (CARs) to target specific cancer cells.
The Treg market is growing rapidly, driven by increasing demand for treatments for autoimmune diseases, allergies, and cancer. Companies in the market include Celgene, Novartis, Kite Pharma, and Juno Therapeutics. Show Less Read more