Top 15 Pharmaceutical Squalene Companies Revolutionizing the Market in 2025–2030
Explore the latest competitive analysis, innovation highlights, and strategic market trends shaping the pharmaceutical squalene industry. This article spotlights the 15 leading pharmaceutical squalene companies driving advancements in drug delivery and vaccines, based on insights from the Pharmaceutical Squalene Market by Source (Animal Derived, Plant Derived, Synthetic), Application (Drug Delivery Emulsions, Vaccines), Disease Indication, Distribution Channel, End-User – Global Forecast 2025-2030 report.
Industry Leaders Transforming the Pharmaceutical Squalene Market
Driven by its pivotal role in drug delivery, vaccines, and high-value therapeutics, the pharmaceutical squalene market is entering a dynamic phase of accelerated growth and technological innovation. Between 2025 and 2030, market leaders are embracing sustainable sourcing, cutting-edge purification, and advanced supply chain strategies to meet rising global healthcare demands. Below, we profile the 15 companies setting industry benchmarks through expertise, specialization, and competitive differentiation.
1. Aasha Biochem
Aasha Biochem stands out for its commitment to sustainable plant-derived squalene production, leveraging advanced extraction technologies from olive and amaranth oils. Their emphasis on scalability and adherence to stringent impurity control protocols align them with the evolving needs of biopharmaceutical innovators. Aasha’s consistent product quality and proactive regulatory engagement have secured them as a partner of choice for drug delivery and vaccine applications.
2. Amyris, Inc.
Amyris, Inc. is globally recognized for its synthetic biology platform, enabling large-scale, reliable squalene supply through fermentation-based processes. As a sustainability-driven innovator, Amyris minimizes reliance on animal feedstocks, offering high-purity ingredients that meet rigorous pharmacopoeial standards. Its deep integration across the value chain enhances transparency and traceability, making Amyris a preferred supplier for pharmaceutical and vaccine manufacturers pursuing green chemistry solutions.
3. BioCatSyn (Shanghai) Biotechnology Co., Ltd.
BioCatSyn excels in biotechnological synthesis, deploying cutting-edge microbial fermentation systems to produce pharmaceutical-grade squalene. The company’s R&D focus on process optimization enables the delivery of squalene with superior consistency and reduced environmental impact. BioCatSyn’s adaptive manufacturing capabilities position it at the forefront of supply innovation for Asia-Pacific’s rapidly expanding vaccine and drug formulation markets.
4. Conscientia Industrial Co., Ltd.
Conscientia Industrial Co., Ltd. distinguishes itself through agile supply chain management and a diversified sourcing model encompassing both animal-derived and plant-based squalene. Its extensive distribution channels and responsive quality assurance protocols make it a valuable partner for pharmaceutical companies navigating variable regulatory landscapes, especially in fast-growing emerging markets.
5. Croda International PLC
Croda International PLC is renowned for high-purity, plant-derived squalene tailored for the most demanding drug delivery and dermatological applications. By investing in sustainable extraction infrastructure and next-generation purification, Croda has reinforced its status as a reliable supplier for global vaccine adjuvant projects, underlining its alignment with stringent global healthcare and environmental standards.
6. Empresa Figueirense de Pesca, Lda
Empresa Figueirense de Pesca, Lda holds a strong legacy in animal-sourced squalene, benefiting from integrated fisheries and robust supply security. While adapting its product portfolio toward more sustainable alternatives, the company leverages deep expertise in extraction and quality control, sustaining relevance in legacy pharmaceutical markets that value proven, consistent performance.
7. Evonik Industries AG
Evonik Industries AG is a global powerhouse providing both synthetic and plant-based squalene, backed by state-of-the-art R&D in lipid technologies. Through ongoing partnerships with biotech startups and academic consortia, Evonik is at the vanguard of novel emulsion and vaccine adjuvant development, offering scalable solutions that adapt quickly to regulatory and market shifts.
8. Kishimoto Special Liver Oil Co., Ltd.
Kishimoto Special Liver Oil Co., Ltd. specializes in high-purity, animal-derived squalene leveraging proprietary extraction and refining techniques honed over decades. Its steadfast commitment to compliance ensures pharmaceutical-grade materials that serve both legacy drug formulation markets and new-generation adjuvant systems within the Asia-Pacific region.
9. Merck KGaA
Merck KGaA is distinguished by its integration of squalene into advanced pharmaceutical delivery platforms, including nanoparticle systems for oncology and infectious disease therapy. The company’s robust analytical capabilities and proven regulatory expertise enable the delivery of bespoke squalene products, reinforcing Merck as a trusted partner for complex drug and vaccine development programs.
10. Otto Chemie Private Limited
Otto Chemie Private Limited is recognized for its broad portfolio of pharmaceutical excipients, with a focus on plant-derived squalene that meets international quality certifications. The company leverages efficient, technology-driven extraction and streamlined logistics to serve both large-scale manufacturers and research-driven formulators across global regions.
11. Seppic S.A.
Seppic S.A. is a leading supplier of pharmaceutical-grade squalene, noted for its dedication to clean-label, plant-based solutions and rigorous traceability. Its investment in process innovation and digital quality management systems underpins the rising demand for high-performance emulsions, topical formulations, and vaccine adjuvants.
12. SOPHIM IBERIA S.L.
SOPHIM IBERIA S.L. combines deep extraction expertise with a robust sustainability agenda, producing high-quality, plant-sourced squalene tailored for demanding pharmaceutical applications. Its agile production and global supply networks strengthen SOPHIM’s ability to support strategic partnerships and respond swiftly to shifting market requirements.
13. Spectrum Chemical Mfg. Corp.
Spectrum Chemical Mfg. Corp. offers a comprehensive range of pharmaceutical ingredients, with squalene products backed by rigorous analytical validation and global distribution capacity. The company’s focus on high-grade purity and flexible packaging options makes it an attractive resource for research institutions and leading pharmaceutical enterprises.
14. SynShark
SynShark pioneers plant-based squalene production through proprietary non-animal biosynthesis and sustainable agricultural practices. The company’s innovative platform delivers consistent, high-purity squalene and positions SynShark as an ethical alternative, particularly appealing to formulators seeking to comply with wildlife conservation and green chemistry mandates.
15. Tokyo Chemical Industry Co., Ltd.
Tokyo Chemical Industry Co., Ltd. stands out for its precision synthesis and strong focus on specialty chemicals, including pharmaceutical-grade squalene for R&D and advanced therapeutic projects. Its dedication to technical support and rapid delivery enables customers to accelerate innovation in drug delivery and vaccine research.
Conclusion: Unlock Full Competitive Insights and Market Forecasts
The future of the pharmaceutical squalene market is shaped by pioneers in sustainable sourcing, formulation technology, and strategic supply chain agility. To dive deeper into supplier profiles, segmentation trends, and regulatory forecasts through 2030, access the comprehensive Pharmaceutical Squalene Market by Source, Application, Disease Indication and More – Global Forecast 2025–2030 report and discover actionable intelligence for investment, procurement, and strategic planning.