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CAR-T Therapy Market Global Report 2020-30

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    Report

  • April 2020
  • Region: Global
  • The Business Research Company
  • ID: 5014057
CAR-T therapy Market Global Report 2020-30 from the author provides the strategists, marketers and senior management with the critical information they need to assess the global car-t therapy market.

Reasons to Purchase
  • Gain a truly global perspective with the most comprehensive report available on this market covering 12+ geographies.
  • Create regional and country strategies on the basis of local data and analysis.
  • Identify growth segments for investment.
  • Outperform competitors using forecast data and the drivers and trends shaping the market.
  • Understand customers based on the latest market research findings.
  • Benchmark performance against key competitors.
  • Utilize the relationships between key data sets for superior strategizing.
  • Suitable for supporting your internal and external presentations with reliable high quality data and analysis
  • Report will be updated with the latest data and delivered to you within 3 working days of order.

Description:

Where is the largest and fastest growing market for the car-t therapy? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The CAR-T therapy market global report from the author answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography. It places the market within the context of the wider car-t therapy market, and compares it with other markets.
  • The market characteristics section of the report defines and explains the market.
  • The market size section gives the market size ($b) covering both the historic growth of the market and forecasting the future. Drivers and restraints looks at the external factors supporting and controlling the growth of the market.
  • Market segmentations break down market into sub markets.
  • The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth. It covers all the regions, key developed countries and major emerging markets. It draws comparisons with country populations and economies to understand the importance of the market by country and how this is changing.
  • Competitive landscape gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
  • The trends and strategies section highlights the likely future developments in the market and suggests approaches companies can take to exploit this.
  • The car-t therapy market section of the report gives context. It compares the car-t therapy market with other segments of the car-t therapy market by size and growth, historic and forecast. It analyses GDP proportion, expenditure per capita, car-t therapy indicators comparison.

Scope

Markets Covered: 1) By Target Antigen: CD19; CD22; Others; 2) By Application: Acute Lymphoblastic Leukemia; Diffuse Large B-Cell Lymphoma; Follicular Lymphoma; Chronic Lymphocytic Leukemia; Multiple Myeloma; Others

Companies Mentioned: Novartis AG; Kite Pharma; Pfizer Inc; Juno Therapeutics; Celgene Corporation

Countries: Brazil, China, France, Germany, India, Indonesia, Japan, South Korea, Russia, UK, USA and Australia

Regions: Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

Time series: Five years historic and ten years forecast.

Data: Ratios of market size and growth to related markets, GDP proportions, per capita expenditure.

Data segmentations: country and regional historic and forecast data, market share of competitors, market segments.

Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.

Table of Contents

1. Executive Summary2. CAR-T therapy Market Characteristics
3. CAR-T therapy Market Size And Growth
3.1. Global CAR-T therapy Historic Market, 2015 - 2019, $ Billion
3.1.1. Drivers Of The Market
3.1.2. Restraints On The Market
3.2. Global CAR-T therapy Forecast Market, 2019 - 2023F, 2025F, 2030F, $ Billion
3.2.1. Drivers Of The Market
3.2.2. Restraints On the Market
4. CAR-T therapy Market Segmentation
4.1. Global CAR-T therapy Market, Segmentation By Target Antigen, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
CD19
CD22
Others
4.2. Global CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
  • Acute Lymphoblastic Leukemia
  • Diffuse Large B-Cell Lymphoma
  • Follicular Lymphoma
  • Chronic Lymphocytic Leukemia
  • Multiple Myeloma
  • Others

5. CAR-T therapy Market Regional And Country Analysis
5.1. Global CAR-T therapy Market, Split By Region, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
5.2. Global CAR-T therapy Market, Split By Country, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
6. Asia-Pacific CAR-T therapy Market
6.1. Asia-Pacific CAR-T therapy Market Overview
6.2. Asia-Pacific CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
7. China CAR-T therapy Market
7.1. China CAR-T therapy Market Overview
7.2. China CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F,$ Billion
8. India CAR-T therapy Market
8.1. India CAR-T therapy Market Overview
8.2. India CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
9. Japan CAR-T therapy Market
9.1. Japan CAR-T therapy Market Overview
9.2. Japan CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
10. Australia CAR-T therapy Market
10.1. Australia CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
11. Indonesia CAR-T therapy Market
11.1. Indonesia CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
12. South Korea CAR-T therapy Market
12.1. South Korea CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
13. Western Europe CAR-T therapy Market
13.1. Western Europe CAR-T therapy Market Overview
13.2. Western Europe CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
14. UK CAR-T therapy Market
14.1. UK CAR-T therapy Market Overview
14.2. UK CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
15. Germany CAR-T therapy Market
15.1. Germany CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
16. France CAR-T therapy Market
16.3. France CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
17. Eastern Europe CAR-T therapy Market
17.1. Eastern Europe CAR-T therapy Market Overview
17.2. Eastern Europe CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
18. Russia CAR-T therapy Market
18.1. Russia CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
19. North America CAR-T therapy Market
19.1. North America CAR-T therapy Market Overview
19.2. North America CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
20. USA CAR-T therapy Market
20.1. USA CAR-T therapy Market Overview
20.2. USA CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
21. South America CAR-T therapy Market
21.1. South America CAR-T therapy Market Overview
21.2. South America CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
22. Brazil CAR-T therapy Market
22.1. Brazil CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
23. Middle East CAR-T therapy Market
23.1. Middle East CAR-T therapy Market Overview
23.2. Middle East CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
24. Africa CAR-T therapy Market
24.1. Africa CAR-T therapy Market Overview
24.2. Africa CAR-T therapy Market, Segmentation By Application, Historic and Forecast, 2015-2019, 2023F, 2025F, 2030F, $ Billion
25. CAR-T therapy Market Competitive Landscape And Company Profiles
25.1. CAR-T therapy Market Competitive Landscape
25.2. CAR-T therapy Market Company Profiles
25.2.1. Novartis AG
25.2.1.1. Overview
25.2.1.2. Products and Services
25.2.1.3. Strategy
25.2.1.4. Financial Performance
25.2.2. Kite Pharma
25.2.2.1. Overview
25.2.2.2. Products and Services
25.2.2.3. Strategy
25.2.2.4. Financial Performance
25.2.3. Pfizer Inc
25.2.3.1. Overview
25.2.3.2. Products and Services
25.2.3.3. Strategy
25.2.3.4. Financial Performance
25.2.4. Juno Therapeutics
25.2.4.1. Overview
25.2.4.2. Products and Services
25.2.4.3. Strategy
25.2.4.4. Financial Performance
25.2.5. Celgene Corporation
25.2.5.1. Overview
25.2.5.2. Products and Services
25.2.5.3. Strategy
25.2.5.4. Financial Performance
26. Key Mergers And Acquisitions In The CAR-T therapy Market27. CAR-T therapy Market Trends And Strategies28. CAR-T therapy Market Future Outlook and Potential Analysis
29. Appendix
29.1. Abbreviations
29.2. Currencies
29.3. Research Inquiries
29.4. About the Publisher
29.5. Copyright And Disclaimer

Samples

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Executive Summary

The CAR-T therapy market consists of sales of CAR-T therapy products and related services involved in providing CAR-T therapy to the cancer patients. The CAR-T therapy is an immunotherapy used to treat cancer by using patient’s own cells. In this therapy, the white blood cells are infused with chimeric antigen receptor that modifies the T-type of white blood cells to fight against cancer cells.

The global CAR-T therapy market was worth $611.31 million in 2019. It is expected to grow at a compound annual growth rate (CAGR) of 51.10% and reach $3,186.23 million by 2023.

The CAR-T therapy market has been geographically segmented into North America, Western Europe, Asia-Pacific, Eastern Europe, South America and Middle East & Africa. North America is expected to be the largest region in the forecast period.

The CAR-T therapy market covered in this report is segmented by target antigen into CD19, CD22, others. It is also segmented by application into acute lymphoblastic leukaemia, diffuse large b-cell lymphoma, follicular lymphoma, chronic lymphocytic leukaemia, multiple myeloma, others.

The CAR-T therapy market is driven by the increasing financial support provided by different organizations to promote the development and consumption of CAR-T therapy. The government and non-government organizations provide financial support to the companies in CAR-T therapy market for research and development and to the patients for their treatment of acute lymphoblastic leukaemia (ALL). For instance, in 2019, the Ministry of Business, Innovation and Employment of New Zealand announced its contribution of $4.9 million over 5 years to its partnership scheme with Malaghan Institute (MI), in order to support the development of CAR T-cell manufacturing in New Zealand. Further, governments in some countries provide subsidy to patients undergoing CAR-T therapy owing to the high cost of the treatment. For example, in 2019, the government of Australia included the CAR-T therapy on the Medicare Benefits Schedule (MBS). The inclusion of (Kymriah®) CAR-T therapy in MBS reduces the cost of the treatment for almost 30 paediatric and young adult (ALL) patients per year in Australia. The financial support provided by different organizations towards CAR-T therapy positively drives the growth of CAR-T therapy market.

The limitations on the application of CAR-T therapy limits the growth of the market. The limitations on CAR-T therapy includes its failure to treat other types of cancer, side effects and the high cost of treatment. CAR-T therapy is widely used as a treatment for a particular type of blood cancer and fails to treat other types of cancers such as lung cancer or breast cancer. Further, in many cases the application of CAR-T therapy results in cytokine release syndrome (CRS). CRS is severe flu like condition causing high fever, nausea, chills, headache, rash, and troubled breathing. Further, the high cost limits the growth of the market. According to an article in HealthLeaders in 2019, the cost of one CAR-T therapy session can be up to $375,000 excluding the overhead charges such as hospital bills. Thus, the growth of the CAR-T therapy is restricted by the various limitations on the application of CAR-T therapy.

The companies in the CAR-T therapy market are conducting clinical trials to assess the ability of CAR-T therapy to treat multiple myeloma. Multiple myeloma is a type of white blood cell cancer where the cancer cells accumulate in the bone marrow and surrounds the healthy blood cells. CAR-T therapy is being tested as a treatment for multiple myeloma. CAR-T cells are modified to target the multiple myeloma causing cells to treat the relapsed or refractory multiple myeloma (RRMM). For instance, Sorrento Therapeutics, a USA based developer of therapeutic approaches to treat different types of cancer, developed CAR2 anti-CD38 CAR-T cell therapy to treat RRMM. The CAR2 anti-CD38 CAR-T cell therapy is in phase 1 of its clinical trial with 72 participant recruitments made by the end of 2019.The aim of the clinical trial is to evaluate the efficiency and safety of CAR2 anti-CD38 CAR-T cell therapy. The trial is expected to be completed in 2020.

In 2019, Novartis, a Switzerland based global medicines company, acquired CellforCure for an undisclosed amount. The acquisition is aimed to increase Novartis' internal production capacity for cell and gene therapies. CellforCure is a French based contract development and manufacturing organization (CDMO) that provides manufacturing facility for cell and gene therapy. CellforCure assisted Novartis in 2017 to manufacture CAR-T treatment named Kymriah.

Major players in the market are Novartis AG, Kite Pharma, Pfizer Inc, Juno Therapeutics, Celgene Corporation, CARsgen Therapeutics, Sorrento Therapeutics and Legend Biotech.

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Novartis AG
  • Kite Pharma
  • Pfizer Inc;
  • Juno Therapeutics
  • Celgene Corporation;
  • CARsgen Therapeutics
  • Sorrento Therapeutics
  • Legend Biotech
  • Mustang Bio
  • Immune Therapeutics
  • Atara Biotherapeutics
  • Aurora Biopharma Inc.
  • Eureka Therapeutics
  • Autolus
  • TILT Biotherapeutics
  • Fortress Biotech.
  • Autolus Therapeutics PLC
  • bluebird bio
  • Carina Biotech;
  • CARTherics
  • Endocyte, Inc.
  • F1 Oncology, Inc.
  • Fate Therapeutics Inc.
  • Gilead
  • Oxford BioMedica PLC.
  • PeproMene Bio Inc.
  • Tessa Therapeutics Pte Ltd.
  • TILT Biotherapeutics Ltd.

Methodology

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