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Adult-onset growth hormone deficiency - Pipeline Insight, 2024

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    Clinical Trials

  • 40 Pages
  • April 2024
  • Region: Global
  • DelveInsight
  • ID: 5262020
This “Adult Growth Hormone Deficiency (AGHD) - Pipeline Insight, 2024,” report provides comprehensive insights about 3+ companies and 3+ pipeline drugs in Adult Growth Hormone Deficiency (AGHD) pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered

  • Global coverage

Adult Growth Hormone Deficiency (AGHD) Understanding

Adult Growth Hormone Deficiency (AGHD): Overview

Adult Growth Hormone Deficiency (AGHD) is a medical condition that occurs when the pituitary gland in brain does not produce enough growth hormone. Most cases of Adult Growth Hormone Deficiency (AGHD) result from damage to the pituitary gland caused by a pituitary tumor or by treatment for this using surgery and/or radiotherapy. Adult Growth Hormone Deficiency (AGHD) is treated with growth hormone replacement therapy. The growth hormone that is used is an artificial preparation that individuals can administer themselves.

Adult Growth Hormone Deficiency (AGHD) - Pipeline Insight, 2024 report outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Adult Growth Hormone Deficiency (AGHD) pipeline landscape is provided which includes the disease overview and Adult Growth Hormone Deficiency (AGHD) treatment guidelines. The assessment part of the report embraces, in depth Adult Growth Hormone Deficiency (AGHD) commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Adult Growth Hormone Deficiency (AGHD) collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights

The companies and academics are working to assess challenges and seek opportunities that could influence Adult Growth Hormone Deficiency (AGHD) R&D. The therapies under development are focused on novel approaches to treat/improve Adult Growth Hormone Deficiency (AGHD).

Adult Growth Hormone Deficiency (AGHD) Emerging Drugs Chapters

This segment of the Adult Growth Hormone Deficiency (AGHD) report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Adult Growth Hormone Deficiency (AGHD) Emerging Drugs

Sogroya (somapacitan-beco): Novo Nordisk Somapacitan-beco binds to a dimeric GH receptor in the cell membrane of target cells resulting in intracellular signal transduction and a host of pharmacodynamic effects. Some of these pharmacodynamic effects are primarily mediated by insulin-like growth factor I (IGF-I) produced in the liver, while others are primarily a consequence of the direct effects of somapacitan-beco. The drug is registered in USA for the treatment of growth hormone deficiency inadults.

TransCon h GH: Ascendis Pharma TransCon hGH is an investigational prodrug of somatropin (human growth hormone) in phase 3 development as a once-weekly therapy for children and adults with GHD. TransCon hGH has orphan designation for GHD in both the U.S.andEurope.

Adult Growth Hormone Deficiency (AGHD): Therapeutic Assessment

This segment of the report provides insights about the different Adult Growth Hormone Deficiency (AGHD) drugs segregated based on following parameters that define the scope of the report, such as:

Major Players in Adult Growth Hormone Deficiency (AGHD)

There are approx. 3+ key companies which are developing the therapies for Adult Growth Hormone Deficiency (AGHD). The companies which have their Adult Growth Hormone Deficiency (AGHD) drug candidates in the mid to advanced stage, i.e. phase III include, Ascendis Pharma and others.

Phases

This report covers around 3+ products under different phases of clinical development like
  • Late-stage products (Phase III)
  • Mid-stage products (Phase II and Phase I/II)
  • Early-stage products (Phase I/II and Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
Route of Administration
Adult Growth Hormone Deficiency (AGHD) pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Subcutaneous
  • Intravenous
  • Oral
  • Intramuscular

Molecule Type

Products have been categorized under various Molecule types such as

  • Small molecules
  • Natural metabolites
  • Monoclonal antibodies

Product Type

Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Adult Growth Hormone Deficiency (AGHD): Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Adult Growth Hormone Deficiency (AGHD) therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Adult Growth Hormone Deficiency (AGHD) drugs.

Adult Growth Hormone Deficiency (AGHD) Report Insights

  • Adult Growth Hormone Deficiency (AGHD) Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs

Adult Growth Hormone Deficiency (AGHD) Report Assessment

  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs

Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Adult Growth Hormone Deficiency (AGHD) drugs?
  • How many Adult Growth Hormone Deficiency (AGHD) drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Adult Growth Hormone Deficiency (AGHD)?
  • What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Adult Growth Hormone Deficiency (AGHD) therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Adult Growth Hormone Deficiency (AGHD) and their status?
  • What are the key designations that have been granted to the emerging drugs?

Key Players

  • Novo Nordisk
  • Ascendis Pharma

Key Products

  • Sogroya
  • TransCon hGH

Table of Contents

IntroductionExecutive Summary
Adult Growth Hormone Deficiency (AGHD): Overview
  • Causes
  • Mechanism of Action
  • Signs and Symptoms
  • Diagnosis
  • Disease Management
Pipeline Therapeutics
  • Comparative Analysis
Therapeutic Assessment
  • Assessment by Product Type
  • Assessment by Stage and Product Type
  • Assessment by Route of Administration
  • Assessment by Stage and Route of Administration
  • Assessment by Molecule Type
  • Assessment by Stage and Molecule Type
Adult Growth Hormone Deficiency (AGHD) - Analytical Perspective
In-depth Commercial Assessment
  • Adult Growth Hormone Deficiency (AGHD) companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Adult Growth Hormone Deficiency (AGHD) Collaboration Deals
  • Company-Company Collaborations (Licensing / Partnering) Analysis
  • Company-University Collaborations (Licensing / Partnering) Analysis
Late -stage Products (Phase III)
  • Comparative Analysis
TransCon hGH: Ascendis Pharma
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
  • Comparative Analysis
Drug name: Company name
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Pre-clinical and Discovery Stage Products
  • Comparative Analysis
Drug name: Company name
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
  • Comparative Analysis
Adult Growth Hormone Deficiency (AGHD) Key CompaniesAdult Growth Hormone Deficiency (AGHD) Key ProductsAdult Growth Hormone Deficiency (AGHD)- Unmet NeedsAdult Growth Hormone Deficiency (AGHD)- Market Drivers and BarriersAdult Growth Hormone Deficiency (AGHD)- Future Perspectives and ConclusionAdult Growth Hormone Deficiency (AGHD) Analyst ViewsAdult Growth Hormone Deficiency (AGHD) Key CompaniesAppendix
List of Tables
Table 1 Total Products for Adult Growth Hormone Deficiency (AGHD)
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
List of Figures
Figure 1 Total Products for Adult Growth Hormone Deficiency (AGHD)
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Novo Nordisk
  • Ascendis Pharma