Mannitol Market - Forecasts from 2023 to 2028

The mannitol market was valued at US$209.4 million in 2021.

Mannitol is a type of sugar polyol or sugar alcohol with low solubility and hygroscopicity and is used as both a sweetener and a drug. Mannitol is naturally found in tree bark, fresh mushrooms, brown algae, seaweed, and most fruits and vegetables. Artificially mannitol is generally manufactured by hydrogenating fructose, which is derived from starch or sucrose. Since the intestines absorb it poorly, mannitol is a low-calorie sweetener. It is used to treat glaucoma by lowering ocular pressure and increasing intracranial pressure. It is administered medically by injection or inhalation. The effects usually start within 15 minutes and extend to 8 hours.

The consumer's quality of life has greatly improved, owing mostly to increased personal income. As a result of rising health consciousness among consumers, the population's eating habits have shifted substantially. Furthermore, firms are investing a lot of time and resources in developing products composed of natural ingredients and specialized goods that improve health. As a result, rising demand for low-calorie natural sweeteners is propelling the growth of the global market for mannitol throughout the projected period. The growing diabetic population is also driving expansion since mannitol has little to no effect on the consumer's blood sugar level.

However, complex laws, restrictions, possible side effects, and a lack of knowledge are restraining the market growth.

The growing demand for mannitol from the food & beverage and pharmaceutical industries is accelerating the market growth.

Mannitol is used as a sweetener in various confectionary goods, especially sugar-free products. Due to low solubility and high latent heat, mannitol is extensively used to produce mint candies and bubble gums. It has a very low hygroscopicity, meaning that it does not absorb water from the air until the humidity level reaches 98 percent, which makes it an excellent covering for hard candies, dried fruits, chocolate coatings, and chewing gums. Mannitol's excellent flavor and texture make it a preferred excipient for chewable tablets.

Mannitol has a lower glycemic index than sucrose and is a sweetener for diabetic patients. Therefore an increasing number of cases of obesity, diabetes, and metabolic syndrome, along with improved consumer awareness, has resulted in a positive expansion of mannitol. Diabetes has affected 537 million people in 2021, according to the IDF. According to forecasts, this figure is expected to rise to 643 million by 2030 and 783 million by 2045. 541 million people are at risk of developing type 2 diabetes.

Mannitol also has therapeutic applications associated with it. It is used to treat glaucoma by lowering ocular pressure and also reduces increased intracranial pressure in case of head trauma. Mannitol is approved in the European Union for treating cystic fibrosis in adults aged 18 and up. It may also treat renal failure with reduced urine production, lower eye pressure, promote the removal of certain toxins, and treat fluid buildup. Therefore, the rising prevalence of diseases such as glaucoma will even further contribute to the market expansion of mannitol. According to CDC data, Glaucoma affects around 3 million Americans. The most common type of glaucoma is open-angle, which causes increasing ocular pressure.

Asia Pacific is anticipated to hold a significant share of the global mannitol market during the forecast period.

Asia Pacific region is anticipated to hold a significant market share in mannitol. This region will witness high growth during the forecast period due to the rising health copiousness among consumers, increased urbanization, and rising disposable income. Mannitol is in high demand in rising markets such as China and India. This region's market is expanding due to changing eating habits and rising demand for low-calorie products and drinks. Mannitol does not affect blood sugar levels, making them an excellent choice for diabetic individuals. As a result, increased diabetes incidence in countries such as India and China is driving demand in this area. According to the International Diabetes Federation, 8.3 percent of Indian adults, or more than 74 million people, have been affected by diabetes in 2021. By 2045, this figure is predicted to rise to 124.8 million. Diabetes affected 13 percent of Chinese adults, or more than 140 million individuals, in 2021. By 2045, this figure is predicted to rise to 174.4 million. In addition, the prevalence of key market players such as Shijiazhuang Huaxu Pharmaceutical Co., Ltd., Singsino Group Ltd., and Shandong Lianmeng International Trade Co are also spurring the growth of mannitol in this region. Prime markets in the Asia Pacific region are India, China, Japan, South Korea, Thailand, Taiwan, and Indonesia.

Market Developments:

• In November 2022, Roquette, a major pharmaceutical and nutraceutical excipients manufacturer, introduced two next-generation mannitol solutions for direct compression: Pearlitol CR-H and Pearlitol 200 GT. Both excipients were created specifically to address unique drug formulation issues in the pharmaceutical industry, assisting manufacturers in optimizing direct compression techniques and expanding into innovative application areas such as controlled-release tablets and tiny tabs.
• In March 2020, SPI Pharma announced the addition of Mannogem XL Opal, Mannogem XL Ruby, Mannogem Emerald, and Mannogem Onyx to its portfolio of Mannogem Mannitol products for usage in numerous patient-friendly oral dose forms. SPI Pharma's new compendial mannitol grades are suited for the formulation of patient-friendly dosage forms such as orally-disintegrating tablets and chewable, with smaller tablet sizes and faster disintegration times, improving patient compliance. They increase the number of choices for resolving challenges with complex formulations, such as content consistency, low API compressibility, and better organoleptic.

Market Segmentation:

By Form

• Powder
• Granules

By Application

• Food
• Pharmaceuticals
• Industrial
• Others

By Geography

• North America
• United States
• Canada
• Mexico
• South America
• Brazil
• Argentina
• Others
• Europe
• United Kingdom
• Germany
• France
• Spain
• Others
• Middle East and Africa
• Saudi Arabia
• UAE
• Israel
• Others
• Asia Pacific
• Japan
• China
• India
• South Korea
• Indonesia
• Thailand
• Others