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mRNA Vaccines Market - Global Forecast 2025-2032

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    Report

  • 183 Pages
  • October 2025
  • Region: Global
  • 360iResearch™
  • ID: 6055092
UP TO OFF until Jan 01st 2026
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The mRNA vaccines market is undergoing significant transformation as regulatory, scientific, and commercial forces reshape strategies and accelerate adoption across multiple healthcare applications. Senior decision-makers must track these shifts to maintain competitiveness and realize growth opportunities in this evolving landscape.

Market Snapshot: mRNA Vaccines Market Growth and Scale

Following an initial surge, the mRNA vaccines market is advancing with sustained growth. Analysts project steady expansion from USD 9.32 billion in 2024 to USD 10.40 billion in 2025, underpinned by a robust compound annual growth rate (CAGR) of 12.17%. This trajectory is expected to drive the market to USD 23.38 billion by 2032.


Momentum is supported by rapid adoption of advanced nucleic acid technologies, increased research and development investment, and evolving business models. Use cases now extend across both preventive and therapeutic healthcare, enabling broader adaptability in response to dynamic medical and market needs. Regional integration and new revenue streams are fueling the competitive positioning of pharmaceutical leaders within this expanding market.

Scope & Segmentation: mRNA Vaccines Market Technologies and Geographies

  • Technology Type: Lipid Nanoparticle (LNP) platforms, nucleoside-modified mRNA, and self-amplifying systems underpin flexible product development and precise patient targeting.
  • Route of Administration: Inhalable, injectable, and oral forms enhance accessibility and facilitate the deployment of personalized vaccination strategies.
  • Manufacturing Process: Cell-free synthesis and in vitro transcription streamline production, supporting greater supply reliability and manufacturing speed.
  • Vaccine Classification: Preventive and therapeutic vaccine options address an expanded set of clinical indications worldwide.
  • Distribution Channel: Hospital and retail pharmacy networks deliver broad reach and support multi-regional product integration.
  • Age Group: Adult, pediatric, and geriatric formulations deliver targeted interventions and enable tailored public health initiatives.
  • Application: Focus areas include autoimmune disorders, infectious diseases such as COVID-19 and Zika, various cancers (e.g., breast cancer, melanoma, glioblastoma), and rare genetic diseases.
  • Geography: The market includes the Americas (US, Canada, Brazil, Mexico, Chile, Argentina, Colombia, Peru), Europe, Middle East & Africa (notably the UK, Germany, France, Russia, Italy, Spain, GCC, and key African countries), and Asia-Pacific (featuring China, India, Japan, Australia, South Korea, and major Southeast Asian economies). Uptake is influenced by healthcare infrastructure and policy priorities.
  • Companies Analyzed: Pfizer Inc., Moderna Inc., BioNTech SE, Acuitas Therapeutics Inc., Arcturus Therapeutics Holdings Inc., AstraZeneca PLC, Chongqing Zhifei Biological Products Co.,Ltd., CureVac N.V., Daiichi Sankyo Company, Limited, Ethris GmbH, GlaxoSmithKline PLC, Regeneron Pharmaceuticals Inc., Roche Holding AG, Sanofi S.A., Sinovac Biotech Ltd., Takeda Pharmaceutical Company Limited, Thermo Fisher Scientific Inc., Recipharm AB, Sartorius AG, Gennova Biopharmaceuticals Limited, Lonza Group AG, Catalent Inc., Laboratorios Farmacéuticos Rovi S.A.

Key Takeaways: Strategic Insights for Stakeholders

  • Industry players are shifting from research-stage innovation to mainstream healthcare adoption, unlocking access to new patient segments and disease targets.
  • Advancements in delivery technology—such as improved nanoparticles and self-amplifying platforms—help lower production lead times and extend access to underserved communities.
  • Geographic regulatory diversity requires tailored market entry strategies, emphasizing local criteria for approval, distribution, and commercialization success.
  • Changing trade policies and tariffs impact sourcing and distribution, calling for robust supply chain strategies and a focus on regional production alliances.
  • Collaborative models between innovators, contract manufacturers, and logistics partners are strengthening value delivery and building operational flexibility.
  • Emerging manufacturing solutions enable agile, scalable production capabilities that can adapt to shifting market demand across borders and therapy areas.

Tariff Impact: Navigating Policy Change and Supply Chain Realignment

Evolving tariff structures are compelling organizations within the mRNA vaccines market to reconsider supply chain strategies, diversify sourcing relationships, and prioritize regional collaborations. These marketplace adjustments influence procurement, research, and clinical rollout timelines. Anticipating policy shifts and scenario planning are vital to ensure sustained product availability and minimize distribution risks.

Methodology & Data Sources

This research draws on interviews with industry leaders, analysis of clinical trial outcomes, patent landscape reviews, and assessment of peer-reviewed literature. Regulatory feedback from multiple stakeholders enhances the credibility and strategic value of the findings.

Why This Report Matters: Actionable Guidance for Senior Decision-Makers

  • Understand benchmarks for technology integration and manufacturing models aligned to market needs and operational strategies.
  • Reinforce organizational resilience through risk management and agile planning that accommodate changes in regulation and supply chain dynamics.
  • Identify partnership and go-to-market opportunities leveraging intelligence to enhance competitive positioning and support successful market entry.

Conclusion

The ability to anticipate trends and integrate responsive strategies supports sustainable growth and portfolio expansion in the mRNA vaccines sector. Senior leaders equipped with these insights can actively drive improvements in patient outcomes and organizational performance.

Table of Contents

1. Preface
1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders
2. Research Methodology
3. Executive Summary
4. Market Overview
5. Market Insights
5.1. Expansion of mRNA technology into personalized oncology vaccines enabled by novel neoantigen targeting
5.2. Strategic alliances between biotech firms and CMOs to scale mRNA vaccine manufacturing capacity worldwide
5.3. Emergence of thermostable mRNA formulations reducing cold chain dependency for global vaccine distribution
5.4. Regulatory fast track approvals and adaptive licensing frameworks accelerating next generation mRNA vaccines
5.5. Integration of artificial intelligence in mRNA sequence optimization to shorten development timelines and costs
5.6. Expansion of self-amplifying mRNA platforms to drive lower dose requirements and wider therapeutic applications
5.7. Increased investment flows and public private partnerships fueling global mRNA vaccine pipeline diversification
5.8. Commercial pivot of COVID-19 mRNA vaccines to annual seasonal boosters in retail channels reshaping payer mix and pricing power in the United States
5.9. Acceleration of multivalent respiratory mRNA vaccines combining COVID-19 and influenza antigens to streamline adult immunization campaigns
5.10. Breakthroughs in organ-targeted lipid nanoparticles enabling extrahepatic delivery to lungs and lymph nodes for improved mucosal and cellular immunity
6. Cumulative Impact of United States Tariffs 2025
7. Cumulative Impact of Artificial Intelligence 2025
8. mRNA Vaccines Market, by Technology Type
8.1. Lipid Nanoparticle (LNP) Platforms
8.2. Nucleoside-Modified mRNA Technologies
8.3. Self-Amplifying mRNA Platforms
9. mRNA Vaccines Market, by Route of Administration
9.1. Inhalable mRNA Vaccines
9.2. Injectable mRNA Vaccines
9.3. Oral Delivery System
10. mRNA Vaccines Market, by Manufacturing Process
10.1. Cell-Free Synthesis
10.2. In Vitro Transcription
11. mRNA Vaccines Market, by Vaccine Classification
11.1. Preventive Vaccines
11.2. Therapeutic Vaccines
12. mRNA Vaccines Market, by Distribution Channel
12.1. Hospital Pharmacies
12.2. Retail Pharmacies
13. mRNA Vaccines Market, by Age Group
13.1. Adult
13.2. Geriatric
13.3. Pediatric
14. mRNA Vaccines Market, by Application
14.1. Autoimmune Diseases
14.2. Infectious Diseases
14.2.1. COVID-19
14.2.2. Cytomegalovirus (CMV)
14.2.3. Ebola
14.2.4. HIV
14.2.5. Influenza
14.2.6. Rabies
14.2.7. Tuberculosis
14.2.8. Zika Virus
14.3. Oncology
14.3.1. Breast Cancer
14.3.2. Glioblastoma
14.3.3. Melanoma
14.3.4. Non-Small Cell Lung Cancer (NSCLC)
14.3.5. Ovarian Cancer
14.3.6. Pancreatic Cancer
14.3.7. Prostate Cancer
14.4. Rare Genetic Disorders
15. mRNA Vaccines Market, by Region
15.1. Americas
15.1.1. North America
15.1.2. Latin America
15.2. Europe, Middle East & Africa
15.2.1. Europe
15.2.2. Middle East
15.2.3. Africa
15.3. Asia-Pacific
16. mRNA Vaccines Market, by Group
16.1. ASEAN
16.2. GCC
16.3. European Union
16.4. BRICS
16.5. G7
16.6. NATO
17. mRNA Vaccines Market, by Country
17.1. United States
17.2. Canada
17.3. Mexico
17.4. Brazil
17.5. United Kingdom
17.6. Germany
17.7. France
17.8. Russia
17.9. Italy
17.10. Spain
17.11. China
17.12. India
17.13. Japan
17.14. Australia
17.15. South Korea
18. Competitive Landscape
18.1. Market Share Analysis, 2024
18.2. FPNV Positioning Matrix, 2024
18.3. Competitive Analysis
18.3.1. Pfizer Inc.
18.3.2. Moderna Inc.
18.3.3. BioNTech SE
18.3.4. Acuitas Therapeutics Inc.
18.3.5. Arcturus Therapeutics Holdings Inc.
18.3.6. AstraZeneca PLC
18.3.7. Chongqing Zhifei Biological Products Co.,Ltd.
18.3.8. CureVac N.V.
18.3.9. Daiichi Sankyo Company, Limited
18.3.10. Ethris GmbH
18.3.11. GlaxoSmithKline PLC
18.3.12. Regeneron Pharmaceuticals, Inc.
18.3.13. Roche Holding AG
18.3.14. Sanofi S.A.
18.3.15. Sinovac Biotech Ltd.
18.3.16. Takeda Pharmaceutical Company Limited
18.3.17. Thermo Fisher Scientific Inc.
18.3.18. Recipharm AB
18.3.19. Sartorius AG
18.3.20. Gennova Biopharmaceuticals Limited.
18.3.21. Lonza Group AG
18.3.22. Catalent, Inc.
18.3.23. Laboratorios Farmacéuticos Rovi, S.A.

Companies Mentioned

The companies profiled in this mRNA Vaccines market report include:
  • Pfizer Inc.
  • Moderna Inc.
  • BioNTech SE
  • Acuitas Therapeutics Inc.
  • Arcturus Therapeutics Holdings Inc.
  • AstraZeneca PLC
  • Chongqing Zhifei Biological Products Co.,Ltd.
  • CureVac N.V.
  • Daiichi Sankyo Company, Limited
  • Ethris GmbH
  • GlaxoSmithKline PLC
  • Regeneron Pharmaceuticals, Inc.
  • Roche Holding AG
  • Sanofi S.A.
  • Sinovac Biotech Ltd.
  • Takeda Pharmaceutical Company Limited
  • Thermo Fisher Scientific Inc.
  • Recipharm AB
  • Sartorius AG
  • Gennova Biopharmaceuticals Limited.
  • Lonza Group AG
  • Catalent, Inc.
  • Laboratorios Farmacéuticos Rovi, S.A.

Table Information