Short-read Sequencing Market - Global Forecast 2025-2032

Short-read sequencing is at the forefront of molecular biology innovation, transforming how genomics, transcriptomics, and diagnostics are approached on a global scale. As competitive pressures and technological advancements intensify, senior executives must understand how market forces, operational risks, and emerging opportunities shape this sector’s direction.

Market Snapshot: Growth Trajectory of the Short-Read Sequencing Market

The short-read sequencing market is experiencing robust growth, advancing from USD 6.73 billion in 2024 to USD 7.84 billion in 2025, with an anticipated CAGR of 16.43%. By 2032, market value is projected to reach USD 22.76 billion. This expansion is driven by ongoing advancements in instrument design, automation, and bioinformatics, alongside increased adoption in clinical and research settings. Market momentum reflects broader shifts in healthcare, agriculture, and biotechnology as organizations look for efficient, high-throughput solutions for complex genetic analysis.

Scope & Segmentation of the Short-Read Sequencing Market

This report delivers comprehensive coverage of principal market segments, geographies, and technological foundations. Key segmentation parameters include:

• Product: • Consumables (Flow Cells & Reagents, Library Prep Kits) • Instruments (Benchtop Sequencers, High-Throughput Sequencers) • Software & Services (Bioinformatics Services, Data Analysis Software)
• Technology: • Semiconductor Sequencing (Ion Proton, Ion Torrent PGM) • Sequencing Ligation • Sequencing Synthesis
• End User: • Academic & Research Institutes • Contract Research Organizations • Hospitals & Diagnostic Labs • Pharma & Biotech Companies
• Application: • Epigenomics (Chromatin Accessibility Analysis, DNA Methylation Analysis) • Genomics (Resequencing, Targeted Sequencing, Whole Genome Sequencing) • Metagenomics • Transcriptomics
• Regional Coverage: • Americas (North America: United States, Canada, Mexico; Latin America: Brazil, Argentina, Chile, Colombia, Peru) • Europe, Middle East & Africa (Europe: United Kingdom, Germany, France, Russia, Italy, Spain, Netherlands, Sweden, Poland, Switzerland; Middle East: United Arab Emirates, Saudi Arabia, Qatar, Turkey, Israel; Africa: South Africa, Nigeria, Egypt, Kenya) • Asia-Pacific (China, India, Japan, Australia, South Korea, Indonesia, Thailand, Malaysia, Singapore, Taiwan)

Key Takeaways for Senior Decision-Makers

• The short-read sequencing market benefits from integrated innovations in reagent chemistry, instrumentation, and sample preparation, enabling cost-effective data generation for broad research and clinical use.
• Strategic alliances between reagent manufacturers, instrument makers, and bioinformatics providers streamline lab workflows, enhance compatibility, and improve operational efficiency across research settings.
• Advanced computational models and cloud-based solutions empower rapid, actionable insights from substantial data sets, supporting cohort analysis and personalized medicine applications.
• Market adoption varies regionally, influenced by funding, regulatory landscapes, and infrastructure maturity; regional adaptation and flexible financing models are increasingly pivotal for market penetration.
• Service-oriented business structures, including subscription-based offerings and outcome-driven pricing, are democratizing access to high-throughput sequencing across underrepresented and emerging markets.
• Collaborative partnerships help mitigate operational risks from global events and regulatory shifts, supporting sustained innovation and supply chain resilience.

Tariff Impact and Supply Chain Strategies

In 2025, new United States import tariffs on essential short-read sequencing consumables and components intensified cost-management concerns across the global supply chain. Pricing adaptations, buffer stock strategies, and a pivot to domestic manufacturing are helping stakeholders navigate procurement volatility. Tiered service contracts and collaborative agreements have also emerged, emphasizing the need for robust supplier diversification and inventory control in mitigating ongoing trade risks.

Methodology & Data Sources

The findings in this report are grounded in structured interviews with senior industry stakeholders, laboratory directors, and procurement leaders across academic, clinical, and industry sectors. Insights were triangulated using data from peer-reviewed literature, regulatory filings, patent databases, and technical white papers. Consistency and analytical rigor were maintained through benchmarking and multi-source validation.

Why This Report Matters for Strategic Leadership

• Gain a clear roadmap detailing how evolving technologies, regulatory policies, and operational strategies impact short-read sequencing markets.
• Identify actionable opportunities for growth across product lines, applications, and regional markets, with guidance to future-proof supply chains and partnerships.
• Support evidence-based planning for investment, procurement, and competitive moves in a rapidly changing environment.

Conclusion

This report provides strategic clarity for stakeholders navigating the fast-evolving short-read sequencing sector. Leaders leveraging these insights will be better positioned to manage risks, capitalize on collaboration, and drive innovation in research and diagnostics.

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