United States Cancer Immunotherapy Market is expected to grow strongly, from US$ 31.82 Billion in 2024 to US$ 71.65 Billion by 2033. This remarkable growth translates to a Compound Annual Growth Rate (CAGR) of 9.44% during the period between 2025 and 2033. The growth in market size is owing to a number of factors such as improvements in biotechnology, research and development spending, and better knowledge of how the immune system can be used to fight cancer.
It is used by itself, or in combination with other therapies, based on the nature and extent of cancer. Clinical trials are underway to add to the number of cancers that can be treated with immunotherapy, in demonstration of its potential to enhance patient survival and quality of life. As science progresses, immunotherapy is promising new and more successful cancer therapies.
2. AstraZeneca
3. Bayer AG
4. Bristol-Myers Squibb Company
5. Pfizer Inc.
6. Novarts AG
7. Johnson & Johnson
8. Eli Lily Company
9. Seattle Genetics Inc.
United States Cancer Immunotherapy Market Outlook
Immunotherapy for cancer is a new way of treatment that uses the body's immune system to recognize and fight cancer cells. Unlike other therapies, including chemotherapy and radiation, that target cancer cells directly, immunotherapy increases the immune response, making the body able to fight cancer more successfully. There are different forms of immunotherapy, such as monoclonal antibodies, checkpoint inhibitors, and cancer vaccines, all aimed at strengthening or restoring the immune system's function to identify and destroy cancer cells. In the USA, cancer immunotherapy is now a key aspect of cancer therapy, especially for cancer types such as melanoma, lung cancer, and bladder cancer.It is used by itself, or in combination with other therapies, based on the nature and extent of cancer. Clinical trials are underway to add to the number of cancers that can be treated with immunotherapy, in demonstration of its potential to enhance patient survival and quality of life. As science progresses, immunotherapy is promising new and more successful cancer therapies.
Growth Drivers in United States Cancer Immunotherapy Market
Escalating Cancer Prevalence and Need for Novel Therapies
2,041,910 new cancer cases and 618,120 cancer deaths are estimated to occur in the United States during 2025. Through 2022, the cancer death rate continued to fall, preventing an estimated 4.5 million deaths since. The rising incidence of cancer in the United States is a key driver of the use of immunotherapy. With millions of Americans suffering from cancers like lung, breast, prostate, and melanoma, there is growing need for treatments with better survival rates and less toxicity than standard chemotherapy. Immunotherapy utilizes the immune system of the body to focus on tumor targeting more specifically, conforming to patient demand for customized treatment. The growing cancer burden, as well as increased knowledge among patients and doctors, continues to propel market expansion as immunotherapy takes its place as a central part of contemporary oncology treatment in the U.S.Strong R&D Pipeline and Biopharmaceutical Innovation
The U.S. market for cancer immunotherapy is supported by solid research and development activities spearheaded by dominant pharmaceutical and biotech companies. Advances in immune checkpoint inhibitors, CAR-T cell therapies, and monoclonal antibodies are broadening therapeutic choices in a range of cancer indications. The FDA's expedited approvals and enabling regulatory models promote quicker commercialization of innovative medicines. Collaboration between academic institutions, research institutions, and industry participants further enhances the development pipeline. With billions spent each year on oncology R&D, the U.S. is still a world leader in developing immunotherapy, giving patients access to innovative treatments and driving ongoing market growth. In 2024, The U.S. Food and Drug Administration (FDA) approved oncology medicines to treat over 50 indications, including 11 first-in-class medicines.Building Healthcare Infrastructure and Reimbursement Support
The sophisticated health care infrastructure in the United States, such as cancer treatment centers and full-fledged oncology networks, facilitates the use of immunotherapy. Expanding reimbursement coverage by Medicare, Medicaid, and private payers for immunotherapy medicines has enhanced patient access to these expensive therapies. Hospitals and cancer centers are increasing immunotherapy services, aided by training programs and clinical trials that are increasing physician experience. Increasing patient interest in new therapies and supportive payer policy guarantee robust utilization. As payers shift reimbursement models to accommodate value-based care, the adoption of immunotherapy will keep increasing, making it a mainstay of cancer therapy in the U.S.Adversities in United States Cancer Immunotherapy Market
High Treatment Costs and Affordability Issues
One of the biggest issues facing the U.S. cancer immunotherapy market is that treatments are very expensive. Therapies such as CAR-T and checkpoint inhibitors are several hundred thousand dollars a year, placing huge burdens on patients and healthcare systems. Despite insurance coverage, co-payments and out-of-pocket costs are still considerable. High costs restrict access, especially for the uninsured or underinsured. These cost issues create concerns over healthcare equity and sustainability. Unless pricing approaches, reimbursement models, and patient support programs change, financial obstacles can slow adoption even with the established clinical value of immunotherapy for the treatment of cancer.Variable Patient Response and Safety Concerns
Even with the exceptional success observed for immunotherapy, not every patient reacts positively to therapy. Response rates are highly variable based on cancer type, genetic makeup, and immune system function. Also, immunotherapy is known to induce major immune-related adverse events, such as lung, liver, and other organ inflammation. These volatile results pose clinical challenges to oncologists and uncertainty to patients. Current research concentrates on biomarkers to select patients most likely to gain benefit, but sparse predictive tools restrict extended precision utilization. Meeting variability in patient response and safety risks management are the major challenges persisting in the U.S. cancer immunotherapy market.United States Immunomodulators Market
The U.S. immunomodulators market is witnessing steady growth, driven by increasing demand for treatments that modulate or augment the immune system's response to cancer. Immunomodulators such as checkpoint inhibitors and cytokine therapies are critical in enhancing immune action against tumor cells. Their use cuts across various cancer types, with growing FDA approvals broadening the treatment universe. The increased emphasis on combination therapies, in which immunomodulators are combined with chemotherapy or targeted therapies, improves clinical efficacy and uptake rates. With deep R&D investment and growing access to new drugs, the immunomodulators market is presented as a vital category in U.S. oncology treatment.United States Cancer Vaccines Market
United States' cancer vaccines market is picking up pace as researchers and biotech companies try to develop preventive and therapeutic vaccines. Preventive vaccines such as HPV have already been successful in preventing cervical and other cancers, and therapeutic vaccines seek to activate the immune system to assault established tumors. Clinical trials are under way for vaccines against lung, prostate, and breast cancer. Government backing for cancer prevention efforts and investment in biotechnology innovation fuel advances in this area. While efficacy issues and mass adoption persist, cancer vaccines are an exciting frontier in the U.S. cancer immunotherapy market.United States Lung Cancer Immunotherapy Market
Lung cancer, the leading type of cancer in the U.S., is a key driver for the adoption of immunotherapy. Immune checkpoint inhibitors like PD-1 and PD-L1 inhibitors are now standard-of-care options for late-stage lung cancer, boosting survival rates significantly. Patients with previously limited treatment opportunities now have more focused and long-lasting responses. On-going clinical studies investigating CAR-T therapy and combination regimens are continuing to evolve the treatment paradigm. With high disease rates of lung cancer, widespread physician acceptance, and extensive FDA approvals, immunotherapy has emerged as a vital tool in enhancing outcomes for U.S. patients with lung cancer.United States Prostate Cancer Immunotherapy Market
Prostate cancer is among the most frequently diagnosed cancers in men in the United States, and the role of immunotherapy is increasingly becoming a viable treatment strategy. Sipuleucel-T, the initial FDA-approved therapeutic cancer vaccine, set the stage for developments in prostate cancer immunotherapy. Checkpoint inhibitors and combination treatments are currently being developed to enhance patient outcomes, especially with advanced or refractory disease. Increased awareness and call for less harmful substitutes of conventional therapies propel adoption. While issues still exist with efficacy in cases in early stages, immunotherapy will increasingly dominate the U.S. prostate cancer treatment market.California Cancer Immunotherapy Market
California is among the leading state markets for cancer immunotherapy based on its robust healthcare infrastructure and innovation ecosystem. With leading cancer research institutions and biotech companies, California is a hotbed for clinical trials and pharmaceutical research. Los Angeles, San Francisco, and San Diego hospitals are at the forefront of adopting immunotherapy, courtesy of highly qualified oncologists. The high population and increasing incidence of cancer in the state drive high demand for new treatments. Proximity to Silicon Valley's biotech innovators also boosts access to latest therapies. California's perfect blend of innovation and demand guarantees its dominance in the U.S. cancer immunotherapy market.New York Cancer Immunotherapy Market
New York's cancer immunotherapy market is growing, driven by its top-tier healthcare facilities and research-oriented culture. Academic medical centers like Memorial Sloan Kettering Cancer Center take the lead in clinical trials, advancing new immunotherapies for different cancers. The state's high population density and elevated incidence of cancer favor strong demand for sophisticated treatment. Immune checkpoint inhibitors, CAR-T therapies, and cancer vaccines are in the forefront of being adopted by New York City hospitals. Excellent collaboration between pharmaceuticals and academia also fuels market expansion further. With its leadership status in cancer research and patient treatment, New York is an important hub for immunotherapy uptake.New Jersey Cancer Immunotherapy Market
New Jersey's immunotherapy market for cancer is fueled by its robust pharmaceutical and biotech sector. Commonly known as the "medicine chest" of America, the state is home to top pharma firms aggressively pursuing immunotherapy R&D and commercialization. Cancer treatment facilities in New Jersey are embracing cutting-edge immunotherapies, with increasing cancer incidence and the need for innovative treatments by patients fueling the growth. Proximity to New York and Philadelphia's major medical centers increases access to specialist services and clinical trials. New Jersey, with its robust industry presence and expanding healthcare infrastructure, is becoming a key player in the U.S. landscape for cancer immunotherapy.Market Segmentation
Products
- Monoclonal Antibodies
- Immunomodulators
- Cancer Vaccines
Application
- Lung Cancer
- Breast Cancer
- Colorectal Cancer
- Melanoma
- Prostate Cancer
- Head & Neck Cancer
- Others
End Users
- Hospital
- Cancer Research Center
- Clinics
Top States
- California
- Texas
- New York
- Florida
- Illinois
- Pennsylvania
- Ohio
- Georgia
- New Jersey
- Washington
- North Carolina
- Massachusetts
- Virginia
- Michigan
- Maryland
- Colorado
- Tennessee
- Indiana
- Arizona
- Minnesota
- Wisconsin
- Missouri
- Connecticut
- South Carolina
- Oregon
- Louisiana
- Alabama
- Kentucky
- Rest of United States
All companies have been covered with 5 Viewpoints
- Overviews
- Key Person
- Recent Developments
- SWOT Analysis
- Revenue Analysis
Key Players Analysis
1. Amgen Inc.2. AstraZeneca
3. Bayer AG
4. Bristol-Myers Squibb Company
5. Pfizer Inc.
6. Novarts AG
7. Johnson & Johnson
8. Eli Lily Company
9. Seattle Genetics Inc.
Table of Contents
1. Introduction3. Executive Summary11. Value Chain Analysis
2. Research & Methodology
4. Market Dynamics
5. United States Cancer Immunotherapy Market
6. Market Share Analysis
7. Products
8. Application
9. End Users
10. Top States
12. Porter's Five Forces Analysis
13. SWOT Analysis
14. Pricing Benchmark Analysis
15. Key Players Analysis
Companies Mentioned
- Amgen Inc.
- AstraZeneca
- Bayer AG
- Bristol-Myers Squibb Company
- Pfizer Inc.
- Novarts AG
- Johnson & Johnson
- Eli Lily Company
- Seattle Genetics Inc.
Methodology
In this report, for analyzing the future trends for the studied market during the forecast period, the publisher has incorporated rigorous statistical and econometric methods, further scrutinized by secondary, primary sources and by in-house experts, supported through their extensive data intelligence repository. The market is studied holistically from both demand and supply-side perspectives. This is carried out to analyze both end-user and producer behavior patterns, in the review period, which affects price, demand and consumption trends. As the study demands to analyze the long-term nature of the market, the identification of factors influencing the market is based on the fundamentality of the study market.
Through secondary and primary researches, which largely include interviews with industry participants, reliable statistics, and regional intelligence, are identified and are transformed to quantitative data through data extraction, and further applied for inferential purposes. The publisher's in-house industry experts play an instrumental role in designing analytic tools and models, tailored to the requirements of a particular industry segment. These analytical tools and models sanitize the data & statistics and enhance the accuracy of their recommendations and advice.
Primary Research
The primary purpose of this phase is to extract qualitative information regarding the market from the key industry leaders. The primary research efforts include reaching out to participants through mail, tele-conversations, referrals, professional networks, and face-to-face interactions. The publisher also established professional corporate relations with various companies that allow us greater flexibility for reaching out to industry participants and commentators for interviews and discussions, fulfilling the following functions:
- Validates and improves the data quality and strengthens research proceeds
- Further develop the analyst team’s market understanding and expertise
- Supplies authentic information about market size, share, growth, and forecast
The researcher's primary research interview and discussion panels are typically composed of the most experienced industry members. These participants include, however, are not limited to:
- Chief executives and VPs of leading corporations specific to the industry
- Product and sales managers or country heads; channel partners and top level distributors; banking, investment, and valuation experts
- Key opinion leaders (KOLs)
Secondary Research
The publisher refers to a broad array of industry sources for their secondary research, which typically includes, however, is not limited to:
- Company SEC filings, annual reports, company websites, broker & financial reports, and investor presentations for competitive scenario and shape of the industry
- Patent and regulatory databases for understanding of technical & legal developments
- Scientific and technical writings for product information and related preemptions
- Regional government and statistical databases for macro analysis
- Authentic new articles, webcasts, and other related releases for market evaluation
- Internal and external proprietary databases, key market indicators, and relevant press releases for market estimates and forecasts
LOADING...
Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 200 |
| Published | August 2025 |
| Forecast Period | 2024 - 2033 |
| Estimated Market Value ( USD | $ 31.82 Billion |
| Forecasted Market Value ( USD | $ 71.65 Billion |
| Compound Annual Growth Rate | 9.4% |
| Regions Covered | United States |
| No. of Companies Mentioned | 9 |
