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Global Manufacturing and Supply Partnering Terms and Agreements in Pharma, Biotech and Diagnostics 2014-2020

  • ID: 1056967
  • Report
  • October 2020
  • Region: Global
  • 1100 Pages
  • CurrentPartnering
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FEATURED COMPANIES

  • 10X Genomics
  • Bened Biomedical
  • Curetis
  • Himed Hospital Management
  • McKesson
  • Penn Pharma
  • MORE
The Global Manufacturing and Supply Partnering Terms and Agreements in Pharma, Biotech and Diagnostics 2014-2020 report.

This report provides details of the latest manufacturing and supply agreements announced in the pharmaceutical, biotechnology, device and diagnostic sectors. Fully revised and updated, the report provides details of manufacturing and supply agreements from 2014 to 2020.

The report provides a detailed understanding and analysis of how and why companies enter manufacturing and supply deals.

A supply or manufacturing agreement is normally between a product manufacturer and product owner in which an owner outsources the manufacture and supply of its product(s) to the service company in a defined territory.

Manufacturing and supply agreements provide a popular method of maximizing the value of a product launched into a market. The deals allow the product marketer to focus on its sales and marketing efforts whilst relying on a third party to manufacture and supply product on demand, enabling rapid response to market demands. It also ensures that the marketer does not need to invest in costly infrastructure and expertise ahead of knowing whether the product will be successful or sustainable.

Understanding the flexibility of a prospective partner’s negotiated deals terms provides critical insight into the negotiation process in terms of what you can expect to achieve during the negotiation of terms. Whilst many smaller companies will be seeking details of the payments clauses, the devil is in the detail in terms of how payments are triggered – contract documents provide this insight where press releases and databases do not.

This report contains a comprehensive listing of over 2,000 manufacturing and supply deals announced since 2014 as recorded in the Current Agreements deals and alliances database, including financial terms where available, plus links to online copies of actual manufacturing and supply contract documents as submitted to the Securities Exchange Commission by companies and their partners.

Contract documents provide the answers to numerous questions about a prospective partner’s flexibility on a wide range of important issues, many of which will have a significant impact on each party’s ability to derive value from the deal.

The initial chapters of this report provide an orientation of manufacturing and supply deal making and business activities. Chapter 1 provides an introduction to the report, whilst chapter 2 provides an analysis of the trends in manufacturing and supply deal making as well as a discussion on the merits of the type of deal.

Chapters 3 and 4 provide an overview of the structure of manufacturing and supply deals. The chapter includes numerous case studies to enable understanding of both pure manufacturing and supply deals and multicomponent deals where manufacturing and supply forms a part.

Chapter 5 provides a review of the leading manufacturing and supply deals since 2014. Deals are listed by headline value. Where the deal has an agreement contract published at the SEC a link provides online access to the contract via the Current Agreements deals and alliances database.

Chapter 6 provides a review of the top 25 most active biopharma companies in manufacturing and supply. Where the deal has an agreement contract published at the SEC a link provides online access to the contract via the Current Agreements deals and alliances database.

Chapter 7 provides a comprehensive and detailed review of manufacturing and supply deals signed and announced since 2014 where a contract document is available. Each deal title links via Weblink to an online version of the actual contract document, providing easy access to each contract document on demand.

The report includes deals announced by hundreds of life science companies including big pharma such as Abbott, Abbvie, Actavis, Amgen, Astellas, AstraZeneca, Baxter, Bayer, Biogen Idec, BMS, Celgene, Eisai, Eli Lilly, Gilead, GSK, J&J, Kyowa Hakko, Merck, Mitsubishi, Mylan, Novartis, Pfizer, Roche, Sanofi, Shire, Takeda, Teva, and Valeant, amongst many others.

The report also includes numerous table and figures that illustrate the trends and activities in manufacturing and supply deal making since 2014.

In addition, a comprehensive appendix is provided organized by manufacturing and supply company A-Z , stage of development, therapeutic target, technology type and deal type definitions. Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

In conclusion, this report provides everything a prospective dealmaker needs to know about manufacturing and supply partnering in the research, development and commercialization of technologies and products.

Key benefits

Global Manufacturing and Supply Partnering Terms and Agreements in Pharma, Biotech and Diagnostics 2014-2020 provides the reader with the following key benefits:
  • In-depth understanding of manufacturing and supply deal trends since 2014
  • Analysis of the structure of manufacturing and supply agreements with numerous real life case studies
  • Comprehensive access to over 2,000 actual manufacturing and supply deals entered into by the world’s biopharma companies
  • Detailed access to actual manufacturing and supply deals entered into by the leading fifty bigpharma companies
  • Comprehensive access to all manufacturing and supply deals entered since 2014
  • Insight into the terms included in a manufacturing and supply agreement, together with real world clause examples
  • Understand the key deal terms companies have agreed in previous deals
  • Undertake due diligence to assess suitability of your proposed deal terms for partner companies
Report scope

Global Manufacturing and Supply Partnering Terms and Agreements in Pharma, Biotech and Diagnostics 2014-2020 is intended to provide the reader with an in-depth understanding of the manufacturing and supply trends and structure of deals entered into by pharma, biotech, device and diagnostics companies worldwide.

Global Manufacturing and Supply Partnering Terms and Agreements in Pharma, Biotech and Diagnostics 2014-2020 includes:
  • Trends in manufacturing and supply dealmaking in the biopharma industry since 2014
  • Analysis of manufacturing and supply deal structure
  • Case studies of real-life manufacturing and supply deals
  • Access to over 2,000 manufacturing and supply deal records covering pharma, biotech, devices and diagnostics since 2014
  • The leading manufacturing and supply deals by value since 2014
  • Most active manufacturing and supply dealmakers since 2014
  • The leading manufacturing and supply partnering resources
In Global Manufacturing and Supply Partnering Terms and Agreements in Pharma, Biotech and Diagnostics 2014-2020, the available deals are listed by:
  • Company A-Z
  • Headline value
  • Stage of development at signing
  • Therapeutic area
  • Technology type
Each deal title links via Weblink to an online version of the actual deal record, providing easy access to each contract document where available.

The Global Manufacturing and Supply Partnering Terms and Agreements in Pharma, Biotech and Diagnostics 2014-2020 report provides comprehensive access to available records for over 2,000 maufacturing and supply deals, including contract documents where available.

Analyzing actual contract agreements allows assessment of the following:
  • What are the precise rights granted or optioned?
  • What is actually granted by the agreement to the partner company?
  • What exclusivity is granted?
  • What is the payment structure for the deal?
  • How are sales and payments audited?
  • What is the deal term?
  • How are the key terms of the agreement defined?
  • How are IPRs handled and owned?
  • Who is responsible for commercialization?
  • Who is responsible for development, supply, and manufacture?
  • How is confidentiality and publication managed?
  • How are disputes to be resolved?
  • Under what conditions can the deal be terminated?
  • What happens when there is a change of ownership?
  • What sublicensing and subcontracting provisions have been agreed?
  • Which boilerplate clauses does the company insist upon?
  • Which boilerplate clauses appear to differ from partner to partner or deal type to deal type?
  • Which jurisdiction does the company insist upon for agreement law?
Note: Product cover images may vary from those shown
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FEATURED COMPANIES

  • 10X Genomics
  • Bened Biomedical
  • Curetis
  • Himed Hospital Management
  • McKesson
  • Penn Pharma
  • MORE
Executive Summary

Chapter 1 - Introduction

Chapter 2 - Trends in manufacturing and supply deal making
2.1. Introduction
2.2. Difference between manufacturing and supply deals
2.3. Trends in manufacturing and supply deals since 2014
2.3.1. Manufacturing and supply deal making by year since 2014
2.3.2. Manufacturing and supply deal making by phase of development since 2014
2.3.3. Manufacturing and supply deal making by industry sector since 2014
2.3.4. Manufacturing and supply deal making by therapy area since 2014
2.3.5. Manufacturing and supply deal making by technology type since 2014
2.3.6. Manufacturing and supply deal making by most active company since 2014
2.3.7. When supply can be useful
2.4. Attributes of pure manufacturing and supply deals
2.5. Attributes of manufacturing and supply in multi-component deals
2.6. Reasons for including manufacturing and supply options in a multi-component deal
2.7. The future of manufacture and supply as part of multicomponent deals

Chapter 3 - Overview of manufacturing and supply deal structure
3.1. Introduction
3.2. Pure versus multi-component manufacturing deals
3.3. Pure manufacturing agreement structure
3.3.1. Example manufacturing agreements
3.3.1.a. Case study 1: Amyris Brazil - Biomin Nutricao Animal Do Brasil
3.3.1.b. Case study 2: Patheon - Orexigen Therapeutics
3.4. Manufacturing rights as part of a wider alliance agreement
3.4.1. Example multicomponent manufacturing clauses
3.4.1.a. Case study 3: Agenus Bio - NewVac
3.4.1.b. Case study 4: Elite Pharmaceuticals - Hi-Tech Pharmacal

Chapter 4 - Overview of supply deal structure
4.1. Introduction
4.2. Supply agreement structure
4.2.1. Example supply agreements
4.2.1.a. Case study 5: Omthera Pharmaceuticals - Catalent Pharma solutions
4.2.1.b. Case study 6: Endo Pharmaceuticals - Noramco
4.3. Supply rights as part of a wider alliance agreement
4.3.1. Example co-marketing right clauses
4.3.1.a. Case study 7: Auxilium Pharmaceuticals - Asahi Kasei
4.3.1.b. Case study 8: Durata Therapeutics - Hospira

Chapter 5 - Leading manufacturing and supply deals
5.1. Introduction
5.2. Top manufacturing and supply deals by value

Chapter 6 - Top 25 most active manufacturing and supply dealmakers
6.1. Introduction
6.2. Top 25 most active manufacturing and supply dealmakers

Chapter 7 - Manufacturing and supply deals contract directory since 2014
7.1. Introduction
7.2. Manufacturing and supply deals with contracts since 2014

Appendices
Appendix 1 - Manufacturing and supply deals by company A-Z
Appendix 2 - Manufacturing and supply deals by stage of development
Appendix 3 - Manufacturing and supply deals by deal type
Appendix 4 - Manufacturing and supply deals by therapy area
Appendix 5 - Manufacturing and supply deals by technology type
Appendix 6 –Deal type definitions

Table of Figures
Figure 1: Definition of manufacturing and supply
Figure 2: Types of manufacturing agreement
Figure 3: Trends in manufacturing and supply deal announcements since 2014
Figure 4: Manufacturing and supply deals signed at each phase of development since 2014
Figure 5: Manufacturing and supply deals by industry sector since 2014
Figure 6: Manufacturing and supply deals by therapy area since 2014
Figure 7: Manufacturing and supply deals by technology type since 2014
Figure 8: Top 25 most active manufacturing and supply dealmakers since 2014
Figure 9: Components of the manufacturing deal structure
Figure 10: Components of the supply deal structure
Figure 11: Top manufacturing and supply deals by value since 2014
Figure 12: Most active manufacturing and supply dealmakers since 2014
Note: Product cover images may vary from those shown
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  • Fujifilm
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  • Johnson & Johnson
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  • K2M
  • Kalon Biotherapeutics
  • Kamada
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  • Kane Biotech
  • Kaneka
  • KangStem Biotech
  • Kapa Biosystems
  • Karolinska Development
  • Karolinska University Hospital
  • KBI BioPharma
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  • Kent Imaging
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  • Khalifa Kush Enterprises
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  • King Faisal Specialist Hospital and Research Center (KFSH&RC)
  • Kings College London
  • Kiniksa Pharmaceuticals
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  • Klaria
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  • Lygos
  • M2i
  • Maastricht University
  • Mabion
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  • Maco Pharma
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  • Macrogen
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  • Magenta Therapeutics
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  • Major Health Partners
  • Mallinckrodt Pharmaceuticals
  • ManRos Therapeutics
  • Maple Leaf Green World
  • Maratek
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  • MarinHealth
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  • Maruho
  • Maryland Proton Therapy Center
  • Maryland State Medical Society
  • Masimo
  • MassBiologics
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  • MaSTherCell
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  • Materialise
  • Max Foundation
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  • McKesson
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  • Medac
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  • Microsoft
  • Midatech
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  • Millar
  • Millipore
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  • MindChild Medical
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  • Ministry of Health (Algeria)
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  • Minomic
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  • MMJ PhytoTech
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  • Modern Dental Group
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  • MYOS
  • myTomorrows
  • N1 Technologies
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  • Nanexa
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  • Princeton University
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  • Retia Medical
  • Reverdia
  • Revive Therapeutics
  • rEVO Biologics
  • ReWalk Robotics
  • Rexgenero
  • RF Surgical Systems
  • Rhode Island Blood Center
  • Richmar
  • Rigel Pharmaceuticals
  • Rite Aid
  • River Vision Development
  • RMX Biopharma
  • Roche
  • Rock-One International
  • Rockwell Medical
  • Rocky Mountain Marijuana
  • Rodan and Fields
  • ROi (Resource Optimization & Innovation)
  • Roivant Sciences
  • Roka Bioscience
  • Romark Laboratories
  • ROTOP Pharmaka
  • Royal Philips Electronics
  • RTI Surgical
  • Rush University Medical Center
  • RVR Diagnostics
  • SACCO
  • SAFC
  • Salix Pharmaceuticals
  • Salus Pharma
  • Salvation Botanicals
  • Sam Chun Dang Pharm
  • Samsung Biologics
  • SanBio
  • Sanbor Medical
  • Sandia National Laboratories
  • Sandoz
  • Saneca Pharmaceuticals
  • Sangamo BioSciences
  • Sanofi
  • Sanomedics
  • Santhera Pharmaceuticals
  • Sarepta Therapeutics
  • Sartorius Stedim Biotech
  • Satellite Healthcare
  • Sato Pharmaceutical
  • Saudi Pharmaceutical Industries & Medical Appliances Corporation (SPIMACO)
  • SAVSU Technologies
  • Sawai Pharmaceuticals
  • SBH Sciences
  • Scandinavian Health
  • Scapa Healthcare
  • Scentryphar
  • Schott
  • Schreiner Group
  • ScieGen Pharmaceuticals
  • Science Exchange
  • Scienion
  • ScinoPharm Taiwan
  • Scripps Health
  • Scripps Research Institute
  • Seattle Children's Hospital
  • Secant Medical
  • Sectra
  • Sedor Pharmaceuticals
  • Seegene
  • Seelos Therapeutics
  • Seibersdorf Laboratories
  • Selecta Biosciences
  • Selectchemie
  • Selexis
  • SELLAS Life Sciences Group
  • Semiotik
  • Seneca
  • Senestech
  • Sensus Healthcare
  • Sepha
  • Seqirus
  • Sequenom
  • Sequential Medicine
  • SeQuent Scientific
  • Serum Institute of India
  • Shandong Luoxin Pharma
  • Shandong Yaohua Medical Instrument
  • Shandong Yaohuo Medical Device Technology Company
  • Shanghai Desano Pharmaceutical
  • Shanghai Institute of Materia Medica
  • Sharp Corporation
  • Shenzhen Yuanxing Bio-Pharm Science & Technology
  • Shibuya Kogyo
  • Shijiazhuang Yuanmai Biotechnology
  • Shine Medical
  • Shionogi
  • Shire Pharmaceuticals
  • Shire US Manufacturing
  • Shoppers Drug Mart
  • Shriners Hospital for Children
  • Shuwen Biotech
  • Si-Bone
  • Siegfried
  • Siemens
  • Siemens Healthineers
  • Sierra Oncology
  • Sigma-Aldrich
  • Silicon Biosystems
  • SillaJen
  • Simbec Research
  • Sinclair Pharmaceuticals
  • Sincopharm
  • Singulex
  • Sino Biopharmaceutical
  • SiO2 Medical Products
Note: Product cover images may vary from those shown
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  • The publisher reports provide insight into the trends and terms of partnering deals in the global life sciences sector.
  • The publisher reports are updated every six months to ensure the user has access to the latest announcements and trends in the topic focus of the report.
  • The publisher analysts review the deal data to provide an overview and analysis of deal trends, including example deals and terms.
  • The publisher reports source deal data from our proprietary deals and alliances database. The database is updated daily by our analysts with new deals as they are announced globally by the company’s party to the deal.
  • The data in the deals and alliances database is obtained from secondary sources such as publicly available industry sources including press releases, company presentations, investor presentations, company SEC filings, other company filings, company websites, conference presentations. Sources are identified to allow for user verification.

The publisher provides comprehensive coverage of the following partnering or deal types:

  • Asset purchase
  • Assignment
  • Co-development
  • Co-market
  • Co-promotion
  • Collaborative R&D
  • Contract service
  • CRADA
  • Cross-licensing
  • Development
  • Distribution
  • Equity purchase
  • Evaluation
  • Grant
  • Joint venture
  • Licensing
  • Loan
  • Manufacturing
  • Marketing
  • Option
  • Promotion
  • Research
  • Royalty financing
  • Settlement
  • Spin out
  • Sub license
  • Supply
  • Termination
  • Warrant

Every deal record is fully categorized and includes the following data, where available:

  • Industry sector
  • Therapy areas
  • Technology type
  • Deal components
  • Financial terms
  • Stage of development
  • Exclusivity
  • Asset type
  • Geographic focus
  • Excluded geography
  • Company press release
  • SEC filing data including contract document

All financial amounts are converted to US$ using the exchange rate available on the date of deal announcement, enabling direct comparison of deal terms across international territories.

 

 

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