The definitive benchmark for cancer monoclonal antibody dealmaking
Cancer monoclonal antibody partnering is driven by targeted biologic therapies, with deal structures reflecting the continued evolution of antibody-based approaches across oncology indications.This report provides a comprehensive and structured analysis of 650+ cancer monoclonal antibody collaboration and licensing deals, delivering a clear and evidence-based view of how partnerships are designed, negotiated, and executed across the market.
Establish a clear view of market standards
The report enables a precise understanding of how monoclonal antibody deals are structured in practice, allowing you to:
- Benchmark comparable transactions with confidence
- Detailed analysis of upfronts, milestones, and royalty structures across relevant deals
- Define realistic market parameters
- Clear insight into how deal terms vary by development stage, antibody type, and partner profile
- Support valuation and structuring decisions with evidence
- Ground internal discussions in real transaction data rather than assumptions
- Understand how leading companies approach dealmaking
- Visibility into partner behaviour and recurring deal structures across a highly competitive and innovation-driven oncology landscape
- Full visibility into deal structure and execution
This includes:
- Rights granted and retained
- Development and commercialization responsibilities
- Financial structures and payment triggers
- Key contractual provisions and protections
Designed for real-world BD and strategy use
The report is widely used to:
- Structure and benchmark oncology biologics transactions
- Prepare for negotiations with well-defined market context
- Evaluate licensing and co-development opportunities
- Support internal strategy with robust, defensible data
What’s included?
- 650+ cancer monoclonal antibody collaboration and licensing deals
- Financial terms, including upfronts, milestones, and royalties where disclosed
- Fully searchable deal directory (by company, therapy, and antibody type)
- Direct access to SEC-filed agreements and source documents
- Analysis of deal trends, key transactions, and active dealmakers
- A trusted, evidence-based reference for cancer monoclonal antibody dealmaking
Table of Contents
Executive SummaryChapter 1 - IntroductionChapter 6 - Cancer monoclonal antibody dealmaking by technology type
Chapter 2 - Trends in cancer monoclonal antibody dealmaking
Chapter 3 - Leading cancer monoclonal antibody deals
Chapter 4 - Most active cancer monoclonal antibody dealmakers
Chapter 5 - Cancer monoclonal antibody contracts dealmaking directory
Deal directory
List of Figures
Companies Mentioned (Partial List)
A selection of companies mentioned in this report includes, but is not limited to:
- 1ST Biotherapeutics
- 3D Medicines
- 3SBio
- 4D Pharma
- A*STAR Agency for Science
- Technology and Research
- Abbvie
- AbClon
- Abdul Latif Jameel Health
- ABL Bio
- Abmuno Therapeutics
- Abpro
- AbTherx
- Abveris
- Abzena
- Accord Healthcare
- Acerta Pharma
- Adagene
- Adaptimmune
- Adaptive Biotechnologies
- Adimab
- Adlai Nortye
- Aduro BioTech
- Advaxis
- Aeglea BioTherapeutics
- AffaMed Therapeutics
- Affimed Therapeutics
- Affinita Biotech
- Agenus Bio
- Agilent Technologies
- AIM ImmunoTech
- Ajinomoto
- Akeso Biopharma
- Akston Biosciences
- Alkyon Therapeutics
- Alligator Bioscience
- Alloy Therapeutics
- Almac Group
- Alphamab Biopharmaceuticals
- Alpine Immune Sciences
- Alteogen
- Alvogen
- Alvotech
- ALX Oncology
- Ambrx
- Amgen
- AmMax Bio
- Amneal Pharmaceuticals
- Ankyra Therapeutics
- Antengene
- Antigen Express
- Apeiron Biologics
- Aperion Biologics
- Apexigen
- Aptevo Therapeutics
- Arch Oncology
- Arcus Biosciences
- argenx
- Arovella Therapeutics
- Array Biopharma
- Ascentage Pharma
- Asher Biotherapeutics
- Asieris MediTech
- Aslan Pharma
- Astellas Pharma
- Astex Pharmaceuticals
- AstraZeneca
- Atara Biotherapeutics
- Athenex
- Atlab Pharma
- Atlante Biotech
- Atlas Antibodies
- Atossa Therapeutics
- AVEO Oncology
- Basilea Pharmaceutica
- Bavarian Nordic
- Baxalta
- Bayer
- BeiGene
- Beijing InnoCare Pharma
- BeOne Medicines
- BerGenBio
- Betta Pharmaceuticals
- Binex
- Bio-Manguinhos/Fiocruz
- Bio-Thera Solutions
- BioAtla
- BioCity Biopharma
- Biocon
- Biocytogen
- Biodesix
- Biogen
- BioInvent
- BiolineRX
- BioMarker Strategies
- Biomm
- Biomunex Pharmaceuticals
- Bioncotech Therapeutics
- Biond Biologics
- BioNTech
- Biosidus
- Biosion
- Biothera Pharmaceuticals
- Biotheus
- BioXcel
- BJ Bioscience
- Blackstone
- Boehringer Ingelheim
- Bolt Biotherapeutics
- Boston Immune Technologies and Therapeutics
- Bpifrance
- BridgeBio Pharma
- Bright Peak Therapeutics
- Bristol-Myers Squibb
- C-Bridge Capital
- California Institute for Regenerative Medicine
- Calithera Biosciences
- CanariaBio
- Cancer Focus Fund
- Cancer Prevention and Research Institute of Texas
- Cancer Research UK
- Cancer Science Institute of Singapore
- CanCure
- Candel Therapeutics
- Cantargia
- Caris Life Sciences
- CARsgen
- Cartexell
- Catalent
- CBT Pharmaceuticals
- Celgene
- Cellectis
- Celltrion
- Celularity
- Cend Therapeutics
- Centre for Drug Research and Development (CDRD)
- CG Oncology
- Champions Oncology
- Checkmate Pharmaceuticals
- Checkpoint Therapeutics
- Chi-Med
- Chime Biologics
- Chiome Bioscience
- Cilag AG
- Cipla
- Circio
- City of Hope Comprehensive Cancer Center
- Clinica Universidad Navarra
- Clovis Oncology
- CMAB Biopharma
- Coherus Biosciences
- Cold Genesys
- Columbia University
- Compass Therapeutics
- Compugen
- Convergent Therapeutics
- Corvus Pharmaceuticals
- Covalab
- Creative Biolabs
- Crescendo Biologics
- Crown Bioscience
- CStone Pharmaceuticals
- Cue Biopharma
- Cullinan Oncology
- Curative Biotechnology
- Curis
- Cytodyn
- Cytovation
- Daiichi Sankyo
- Debiopharm
- Department of Defense
- Diaprost
- Distributed Bio
- Dr. Reddy's Laboratories
- Dragonfly Therapeutics
- Earendil Labs
- eFFECTOR Therapeutics
- EirGenix
- Eisai
- Elevar Therapeutics
- Elevation Oncology
- Elicio Therapeutics
- Eli Lilly
- ElsaLys Biotech
- Enlivex
- Enzolytics
- EpiThany
- EQRx
- Erasca
- Erasmus University Medical Center
- Essex Bio-Technology
- Eucure Biopharma
- Eurofarma
- European Union Regional Development Fund
- EUSA Pharma
- Eutilex
- Evaxion Biotech
- Everest Medicines
- Evopoint Biosciences
- Excellmab
- Exelixis
- F-Star Therapeutics
- FatiAbGen
- Five Prime Therapeutics
- Flare Therapeutics
- FLX Bio
- Formosa Pharmaceuticals
- Formycon
- Forty Seven
- Fosun Kite Biotechnology
- Fosun Pharmaceutical
- Fred Hutchinson Cancer Research Center
- Fuhong Hanlin
- Fusion Pharmaceuticals
- Galaxy Biotech
- Galecto
- GBI BioManufacturing
- GC Cell
- Genentech
- Genexine
- GenFleet Therapeutics
- Genmab
- Genome and Company
- Genor Biopharma
- Genprex
- GenScript Biotech
- Georgetown University
- GI Innovation
- Gilead Sciences
- Glenmark Pharmaceuticals
- Glycotope Biotechnology
- Glythera
- Gossamer Bio
- GO Therapeutics
- Gradalis
- Granite Bio
- Gritstone Bio
- GSK
- H-Immune
- H3 Biomedicine
- Halozyme Therapeutics
- Harbour Biomed
- Heidelberg Pharma
- Hengenix Biotech
- Henlius Biotech
- HiberCell
- HIBio
- HiFiBio
- Highlight Therapeutics
- Hikma Pharmaceuticals
- Hisun BioRay
- Hoffmann La Roche
- Hookipa Pharma
- Hualan Genetic
- Humanigen
- Hummingbird Bioscience
- Hutchison MediPharma
- Huyabio International
- Hypospray Pharma
- I-mab
- Iambic Therapeutics
- iBio
- IcanoMAB
- iDD Biotech
- IDEAYA Biosciences
- ImCheck Therapeutics
- ImClone Systems
- Immatics Biotechnologies
- Immix Biopharma
- Immune-Onc Therapeutics
- Immuneering
- ImmuneOncia Therapeutics
- Immune Pharmaceuticals
- Immunicum
- Immunitas Therapeutics
- ImmunityBio
- ImmunoChina Pharmaceuticals
- Immunocore
- ImmunoGen
- Immunome
- Immunomedics
- Immunovaccine
- Immutep
- IMPACT Therapeutics
- Imugene
- IMV
- Incyte
- Indaptus Therapeutics
- Infinity Pharmaceuticals
- InflaRx
- Innate Pharma
- Innovent Biologics
- Inovio
- Inspirna
- Institut Bergonie
- Intas Pharmaceuticals
- Integral Molecular
- Intensity Therapeutics
- InxMed
- IO Biotech
- Ionova
- IONTAS
- Ipsen
- IRBM
- ISA Pharmaceuticals
- Italian Association for the Study of Pancreas
- iTeos Therapeutics
- Jacobio Pharmaceuticals
- Janssen Biotech
- Janssen Research & Development
- Jazz Pharmaceuticals
- JHL Biotech
- Jiangsu Alphamab
- Jiangsu Hansoh Pharmaceutical
- Jiangsu Hengrui Medicine
- Jiangsu Hengrui Pharmaceuticals
- Johns Hopkins University
- Jounce Therapeutics
- Junshi Biosciences
- KAHR Medical
- Kalbe Genexine Biologics
- KaliVir Immunotherapeutics
- Kelun-Biotech Biopharmaceutical
- Kineta
- Kiniksa Pharmaceuticals
- Kintor
- Kite Pharma
- Kolltan Pharmaceuticals
- Kymab
- Laekna
- Lassen Therapeutics
- Lava Therapeutics
- Leap Therapeutics
- Leica Biosystems
- LEO Pharma
- Les Laboratoires Servier
- Leukemia & Lymphoma Society
- Leveragen
- LG Life Sciences
- LifeMax Laboratories
- Ligand Pharmaceuticals
- Link Cell Therapies
- Linnaeus Therapeutics
- Livzon Mabpharm
- Lonza
- LOTTE Biologics
- Lumos Pharma
- Lunit
- Lupagen
- Lyvgen Biopharma
- MAB Discovery
- mAbsolve
- mAbXience
- Macrogenics
- MAIA Biotechnology
- Manhattan BioSolutions
- Massachusetts General Hospital
- Mayo Clinic
- MD Anderson Cancer Center
- Medical Research Council
- Medicenna Therapeutics
- MediLink Therapeutics
- MedImmune
- Medison Pharma
- Memorial Sloan Kettering Cancer Center
- Merck and Co
- Merck KGaA
- Merck Sharpe & Dohme
- Mereo BioPharma
- Merrimack Pharmaceuticals
- Merus
- Microbiotica
- Mirror Biologics
- Mitra Biotech
- Molcure
- Moleculin Biotech
- Monopar Therapeutics
- MorphoSys
- Morphotek
- Mount Sinai Health System
- MSD
- MS Pharma
- Mundipharma
- Mustang Bio
- Mylan Pharmaceuticals
- Myriad Genetics
- Nanjing Leads Biolabs
- Nascent Biotech
- National Cancer Institute
- National Center for Tumor Diseases
- National Comprehensive Cancer Network (NCCN)
- National Institutes of Health
- National University Cancer Institute
- Navrogen
- Nectin Therapeutics
- Nektar Therapeutics
- Nelum Pharma
- NeoImmuneTech
- Neoleukin Therapeutics
- Neon Therapeutics
- NETRIS Pharma
- Neuroblastoma and Medulloblastoma Translational Research
- Nexvet
- NGM Biopharmaceuticals
- NiKang Therapeutics
- NKGen Biotech
- NKMax America
- Nobelpharma
- Noetik
- Nona Biosciences
- Nordic Society of Gynaecological Oncology
- Nouscom
- NovalGen
- Novartis
- Novelogics Biotechnology
- Novocure
- Noxopharm
- Noxxon Pharma
- Numab
- Nykode Therapeutics
- OBI Pharma
- Olatec Therapeutics
- Olivia Newton-John Cancer Research Institute
- OncoC4
- OncoCare Therapeutics
- OncoImmune
- Oncologie
- Oncolytics Biotech
- OncoQuest
- OncoResponse
- OncoSec Medical
- OncoVerity
- Oncternal Therapeutics
- Oncurious
- OncXerna Therapeutics
- Ono Pharmaceutical
- Ordaos Bio
- ORIC Pharmaceuticals
- Orion
- OSE Immunotherapeutics
- Oxford BioTherapeutics
- Panacea Pharmaceuticals
- Partner Therapeutics
- Pascal Biosciences
- PDS Biotechnology
- Percheron Therapeutics
- Peregrine Pharmaceuticals
- Personal Genome Diagnostics
- Personalis
- Pfizer
- Phanes Therapeutics
- PharmAbcine
- Pharmapark
- Pieris Pharmaceuticals
- Pierre Fabre
- Pionyr Immunotherapeutics
- PlantForm
- PlantPraxis Biotecnologia
- PMV Pharma
- Pneuma Respiratory
- POINT Biopharma
- Portage Biotech
- Poseida Therapeutics
- Precision BioSciences
- Prelude Therapeutics
- Prestige BioPharma
- ProBioGen
- Progenetics
- Progenics Pharmaceuticals
- Promega
- ProtoKinetix
- PT Etana Biotechnologies
- PULSALYS
- Purdue University
- PureTech Health
- Pyxis Oncology
- QBiotics
- QIAGEN
- Quantum Leap Health Care Collaborative
- Quest PharmaTech
- Qurient
- Radboud University Nijmegen Medical Centre
- Rakuten Medical
- RefleXion Medical
- Regeneron Pharmaceuticals
- Regnum
- RemeGen
- Replimune
- Rexahn Pharmaceuticals
- Roche
- Roswell Park Cancer Institute
- RubrYc Therapeutics
- Rxilient Biotech
- Rznomics
- Saccharo
- Samsung Bioepis
- Samsung Biologics
- Samyang Biopharmaceuticals
- Sandoz
- Sanofi
- Sanofi-Aventis
- Sarah Cannon Research Institute
- SATT Sud-Est
- Scancell
- Scandion Oncology
- Schrodinger
- SciClone Pharmaceuticals
- Scripps Research Institute
- Seagen
- Seattle Genetics
- Seismic Bio
- Selecxine
- Selexis
- SELLAS Life Sciences Group
- Sensei Biotherapeutics
- Seven and Eight Biopharmaceuticals
- SevenScore Pharmaceuticals
- Sharp HealthCare
- Shenogen Pharma
- Shenzhen Chipscreen Biosciences
- Simcere Pharmaceuticals
- Simcha Therapeutics
- Sirnaomics
- Solstice Oncology
- Sonnet BioTherapeutics
- Sorrento Therapeutics
- Sosei Heptares
- SOTIO
- Spanish National Research Council
- Specialised Therapeutics
- Specialized Medical Services-oncology
- STADA Arzneimittel
- Storm Therapeutics
- Strata Oncology
- Sud Investments
- Surface Oncology
- Symphogen
- Syndax Pharmaceuticals
- Synlogic
- Synthekine
- Syros Pharmaceuticals
- T-Cure Bioscience
- Taiho
- Takeda Pharmaceutical
- Talem Therapeutics
- TARIS Biomedical
- Tavotek Biotherapeutics
- TCR2 Therapeutics
- Telix Pharmaceuticals
- Tempest Therapeutics
- TeneoBio
- Teon Therapeutics
- Tesaro
- Tessa Therapeutics
- Tetragenetics
- Teva Pharmaceutical Industries
- TG Therapeutics
- The Jackson Laboratory
- Theranyx
- Thermo Fisher Scientific
- ThromboGenics
- TILT Biotherapeutics
- Tiziana Life Sciences
- Tizona Therapeutics
- TJ Biopharma
- Tmunity Therapeutics
- Torque Therapeutics
- TRACON Pharmaceuticals
- Transcenta
- Transgene
- TransPerfect Life Sciences
- TransThera
- Trianni
- Trieza Therapeutics
- Trio Pharmaceuticals
- Triumvira Immunologics
- Tubulis
- Turgut Ilaclari
- Twist Bioscience
- UbiVac
- UCB
- Universite Claude Bernard Lyon
- University of Alabama at Birmingham
- University of Bergen
- University of British Columbia
- University of California
- San Diego
- University of California Los Angeles
- University of California San Francisco
- University of Florida
- University of New Mexico
- University of Wisconsin Carbone Cancer Center (UWCCC)
- UroGen Pharma
- Vaccinex
- Vaximm
- Vcell Healthcare
- Vedanta Biosciences
- Verseau Therapeutics
- Viela Bio
- Vyriad
- Wellmarker Bio
- Werewolf Therapeutics
- Wilex
- WindMIL Therapeutics
- WuXi Biologics
- Wuxi Shuangliang Biotechnology
- Xencor
- Xilio Therapeutics
- Xoma
- Xuanzhu Biopharma
- Xyphos Biosciences
- Y-Biologics
- Y-mAbs Therapeutics
- Yale Cancer Center
- Yale University
- ZAI Laboratory
- Zenoaq
- Zhejiang Bossan Pharmaceutical
- Zhejiang Hisun Pharmaceutical
- Zhejiang Huahai Pharmaceutical
- Zumutor Biologics
- Zydus Cadila
- Zydus Lifesciences
Methodology
- The publisher reports provide insight into the trends and terms of partnering deals in the global life sciences sector.
- The publisher reports are updated every six months to ensure the user has access to the latest announcements and trends in the topic focus of the report.
- The publisher analysts review the deal data to provide an overview and analysis of deal trends, including example deals and terms.
- The publisher reports source deal data from our proprietary deals and alliances database. The database is updated daily by our analysts with new deals as they are announced globally by the company’s party to the deal.
- The data in the deals and alliances database is obtained from secondary sources such as publicly available industry sources including press releases, company presentations, investor presentations, company SEC filings, other company filings, company websites, conference presentations. Sources are identified to allow for user verification.
The publisher provides comprehensive coverage of the following partnering or deal types:
- Asset purchase
- Assignment
- Co-development
- Co-market
- Co-promotion
- Collaborative R&D
- Contract service
- CRADA
- Cross-licensing
- Development
- Distribution
- Equity purchase
- Evaluation
- Grant
- Joint venture
- Licensing
- Loan
- Manufacturing
- Marketing
- Option
- Promotion
- Research
- Royalty financing
- Settlement
- Spin out
- Sub license
- Supply
- Termination
- Warrant
Every deal record is fully categorized and includes the following data, where available:
- Industry sector
- Therapy areas
- Technology type
- Deal components
- Financial terms
- Stage of development
- Exclusivity
- Asset type
- Geographic focus
- Excluded geography
- Company press release
- SEC filing data including contract document
All financial amounts are converted to US$ using the exchange rate available on the date of deal announcement, enabling direct comparison of deal terms across international territories.
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