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Glucose Homeostatis and the Pathogenesis of Diabetes Mellitus. Progress in Molecular Biology and Translational Science Volume 121

  • Book

  • February 2014
  • Elsevier Science and Technology
  • ID: 2711571

Diabetes mellitus is a disease with tremendous health and economic burden. A better understanding of how normal glucose homeostasis is maintained and the pathogenesis is important to identify new ways for diabetes treatment. This book addresses multiple aspects of this area of research.

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Table of Contents

  1. G Protein-Coupled Receptors as Regulators of Glucose Homeostasis and Therapeutic Targets for Diabetes Mellitus
    Ya-Xiong Tao and Xu-Fang Liang
  2. Regulation of Glucose Homeostasis by GLP-1
    Prashant Nadkarni, Oleg G. Chepurny and George G. Holz
  3. Physiology and Therapeutics of the Free Fatty Acid Receptor GPR40
    Hui Huang, Meng-Hong Dai and Ya-Xiong Tao
  4. Targeting GPR119 for the Potential Treatment of Type 2 Diabetes Mellitus
    Xiu-Lei Mo, Zhao Yang and Ya-Xiong Tao
  5. Enhanced Skeletal Muscle for Effective Glucose Homeostasis
    Jinzeng Yang
  6. Factors Affecting Insulin-regulated Hepatic Gene Expression
    Hong-Ping Guan and Guoxun Chen
  7. Roles of Peroxisome Proliferator-Activated Receptors (PPARs) in the Metabolic Syndrome
    Mahmoud Mansour
  8. Free Fatty Acids and Skeletal Muscle Insulin Resistance
    Lyudmila I. Rachek
  9. Adiponectin Signaling and Metabolic Syndrome
    Yuchang Fu
  10. Regulation of Pancreatic Islet Beta-Cell Mass by Growth Factor and Hormone Signaling
    Yao Joyce Huang and Yongchang Chang
  11. The Impact of Dietary Methionine Restriction on Biomarkers of Metabolic Health
    Manda L. Orgeron, Kirsten P. Stone, Desiree Wanders, Cory C. Cortez, Nancy T. Van and Thomas W. Gettys
  12. Carbohydrate Metabolism and Pathogenesis of Diabetes Mellitus in Dogs and Cats
    Margarethe Hoenig
  13. Impaired Insulin Signaling and Mechanisms of Memory Loss
    Jenna Bloemer, Subhrajit Bhattacharya, Rajesh Amin and Vishnu Suppiramaniam
  14. The Role of PPARd Signaling in the Cardiovascular System
    Yishu Ding, Kevin D. Yang and Qinglin Yang