Aging: Oxidative Stress and Dietary Antioxidants bridges the trans-disciplinary divide and covers in a single volume the science of oxidative stress in aging and the potentially therapeutic use of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial, and oxidative stress is a single component of this.
Gerontologists, geriatricians, nutritionists, and dieticians are separated by divergent skills and professional disciplines that need to be bridged in order to advance preventative as well as treatment strategies. While gerontologists and geriatricians may study the underlying processes of aging, they are less likely to be conversant in the science of nutrition and dietetics. On the other hand, nutritionists and dietitians are less conversant with the detailed clinical background and science of gerontology. This book addresses this gap and brings each of these disciplines to bear on the processes inherent in the oxidative stress of aging.
- Nutritionists can apply information related to mitochondrial oxidative stress in one disease to diet-related strategies in another unrelated disease
- Dietitians can prescribe new foods or diets containing anti-oxidants for conditions resistant to conventional pharmacological treatments
- Dietitians, after learning about the basic biology of oxidative stress, will be able to suggest new treatments to their multidisciplinary teams
- Nutritionists and dietitians will gain an understanding of cell signaling and be able to suggest new preventative or therapeutic strategies with anti-oxidant rich foods
1. Skin aging and oxidative stress 2. Sarcopenia and oxidative stress 3. Ovarian aging and oxidative stress 4. The brain in aging and oxidative stress 5. Alzheimer's disease and oxidative stress 6. The heart, aging and oxidative stress 7. Age-related changes in the cardiovascular system 8. The immune system in aging and role of oxidative stress 9. The lung in aging and oxidative stress 10. Diseases of aging: Cancer and oxidative stress 11. Skin aging and vitamin C 12. Aging skin and natural estrogenic antioxidants 13. Nutricosmetics and skin aging 14. Antioxidant nutrition and sarcopenia 15. Magnesium, oxidative stress and aging muscl 16. Ascorbic acid in postmenopausal women and artery compliance 17. Effects of tocopherol supplements on menopausal disorders 18. Antioxidant aspects of plum to treat menopausal symptoms and effects on body systems 19. Statins and reduction in oxidative stress in aged brain 20. Saffron and the aged brain: antioxidant aspects 21. Green tea catechins and the aging brain 22. Metals and oxidative stress in Alzheimer's disease 23. Alzheimer's disease and plant derived melatonin 24. Antioxidants in Alzheimer's disease 25. Antioxidant vitamins and cardiovascular disease 26. Oxidative stress, carotenoids and cardiovascular protection 27. Hypertension, menopause and natural antioxidants 28. Selenium and heart disease in aging 29. Vitamin C and heart failure 30. Immune function and coffee consumption in the aged 31. Immune systems and food based strategies in the aged 32. Immune changes in aging and dietary antioxidants 33. Minerals and COPD 34. Vitamin E and lung disease in the elderly 35. Vitamins and breast cancer 36. Vitamin E and colorectal cancer 37. Coffee consumption and cancer mortality 38. Garlic extracts and cancer 39. Red wine and prostate cancer
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a staff member of the Faculty of Life Sciences and Medicine within King's College London. He is also a member of the Division of Diabetes and Nutritional Sciences (research) and the Department of Nutrition and Dietetics (teaching). Professor Preedy is also Director of the Genomics Centre of King's College London.
Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctorate (DSc), for his outstanding contribution to protein metabolism in health and disease. Professor Preedy was elected as a Fellow to the Institute of Biology in 1995 and to the Royal College of Pathologists in 2000. Since then he has been elected as a Fellow to the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. Professor Preedy has carried out research when attached to Imperial College London, The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with research groups in Finland, Japan, Australia, USA and Germany. Prof Preedy is a leading expert on the science of health and has a long standing interest in neurological disease and tissue pathology. He has lectured nationally and internationally. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.