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Cognitive Enhancement. Pharmacologic, Environmental and Genetic Factors

  • Book

  • January 2015
  • Elsevier Science and Technology
  • ID: 2857102

Cognitive Enhancement: Pharmacologic, Environmental and Genetic Factors addresses the gap that exists in research on the topic, gathering multidisciplinary knowledge and tools that help the reader understand the basics of cognitive enhancement. It also provides assistance in designing procedures and pharmacological approaches to further the use of novel cognitive enhancers, a field that offers potential benefit to a variety of populations, including those with neurologic and psychiatric disorders, mild aging-related cognitive impairment, and those who want to improve intellectual performance.

The text builds on our knowledge of the molecular/cellular basis of cognitive function, offering the technological developments that may soon enhance cognition. Separate sections cover enhancement drugs, environmental conditions, and genetic factors in terms of both human and animal studies, including both healthy/young and aging/diseased individuals.

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Table of Contents

1. What Is Cognitive Enhancement?

2. Signaling Pathways Involved in Cognitive Enhancement

3. Molecular Mechanisms of Drug-Induced Cognitive Enhancement

4. Role of Environment, Epigenetics and Synapses in Cognitive Enhancement

5. Transgenic Mice with Enhanced Cognition

6. The Use of Viral Vectors to Enhance Cognition

7. Advancing Fear Memory Research with Optogenetics

8. Can Stem Cells be used to Enhance Cognition?

9. Alzheimer's Disease and Mechanism-Based Attempts to Enhance Cognition

10. Pharmacological treatment of cognitive dysfunction in neuropsychiatric disorders

11. Cognitive Enhancement in Humans

12. The Use of Transcranial Direct Current Stimulation for Cognitive Enhancement

13. Cognitive Enhancement: Ethical Considerations and a Look into the Future

Authors

Shira Knafo The University of the Basque Country, Biophysics Unit, Leioa, Spain. Shira Knafo is the head of the Molecular Cognition Laboratory and an Ikerbasque research professor at The University of the Basque Country (Biophysics Unit, Leioa). Her particular interests are in studying the molecular and synaptic mechanisms underlying learning and memory processes, cognitive malfunction and cognitive enhancement. Her experience in different scientific disciplines (medicine, animal behaviour, electrophysiology, molecular biology, morphology and imaging) allows her to adopt a multidisciplinary approach that is considered a great asset in modern neuroscience research. In 2012, she was awarded the Sieratzki Prize for Advances in Neuroscience (Tel-Aviv University) for her contributions in the field of cognitive neuroscience. In the same year, the Spanish National Research Council acknowledged her achievements in its annual tribute to its scientists. In 2013, the Spanish Ministry of Science awarded her an I3 certificate of excellence. César Venero Universidad de Educación a Distancia, Madrid, Spain. Associate Professor, Department of Psychopharmacology at the Universidad de Educación a Distancia in Spain and is Director of the Lab for Neurobiology of Stress and Neurodegenerative Diseases. He has authored two books on psychopharmacology and memory work. He co-chaired the "Cognitive Enhancement in Health and Disease” symposium at the 2012 Federation for European Neuroscience annual meeting.