The application of cannabis sativa for the treatment of neurologic and mental disease is expanding. Cannabinoids in Neurologic and Mental Disease collects and presents for the first time recent research involving the use of pharmacological cannabinoids for the treatment of neurodegenerative and neuroinflammatory disease. The neurologic application of cannabinoid therapy builds upon psychiatric and psychological use for the treatment of a variety of core mental disorders. This comprehensive reference on the known uses of cannabinoids will be useful for clinical neurologists, neuroscience and clinical neuroscience researchers, clinical psychologists and psychiatrists and the general medical community.
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Table of Contents
The ever expanding world of the endocannabinoids: a concise introduction Fabiana Piscitelli and Vincenzo Di Marzo
PART I: ROLE OF THE ENDOCANNABINOIDS IN NEUROINFLAMMATORY AND NEURODEGENERATIVE DISORDERS 1. Cannabinoids for the treatment of Neuroinflammation Maria L. de Ceballos 2. Endocannabinoids and Alzheimer's Disease Steven George Fagan and Veronica A. Campbell 3. Cannabinoids in Parkinson's Disease Eilís Dowd 4. Cannabinoids and Huntington's Disease Cindy Casteels, Rawaha Ahmad, Matheiu Vandenbulcke, Wim Vandenberghe and Koen Van Laere 5. Endocannabinoids and Amyotrophic Lateral Sclerosis Eva de Lago, Miguel Moreno-Martet, Francisco Espejo-Porras and Javier Fernández-Ruiz 6. Endocannabinoids and Epilepsy Robert E. Blair, Laxmikant Deshpande and Robert J. DeLorenzo 7. Endocannabinoids and Migraine Cristina Tassorelli
PART II: ROLE OF THE ENDOCANNABINOIDS IN PSYCHOLOGICAL AND PSYCHIATRIC DISORDERS 8. Cannabinoids and Schizophrenia Cathrin Rohleder and F. Markus Leweke 9. Cannabinoids and Bipolar Disorder Raphael J. Braga, Sherif Abdelmessih, Juliana Tseng and Anil Kumar Malhotra 10. Cannabinoids and Tourette syndrome Kirsten R. Müller-Vahl 11. The Role of Endocannabinoid Function in Posttraumatic Stress Disorder: Modulating the Risk Phenotype and Rendering Effects of Trauma Frances H. Gabbay, Kwang H. Choi, Gary Wynn and Robert J. Ursano 12. Cannabinoids and Drug Addiction Maria Antonietta De Luca and Liana Fattore 13. Cannabinoids and appetite (dys)regulation (Obesity) - Claire M. Williams, Benjamin J. Whalley and Ciara McCabe
PART III: ROLE OF THE ENDOCANNABINOIDS IN IMPULSIVE AND COMPULSIVE DISORDERS 14. The cannabinoid system and impulsive behavior Joost Wiskerke and Tommy Pattij 15. Cannabinoids and compulsive-obsessive disorder Plinio C. Casarotto, Felipe V. Gomes and Francisco Silveira Guimarães 16. The endocannabinoid system: anorexia nervosa and binge eating disorder Maria Scherma, Valentina Satta, Walter Fratta and Paola Fadda 17. The Endocannabinoid System and Trichotillomania: A Promising Target for Treatment? - Jon E. Grant, Brian L. Odlaug and Samuel R. Chamberlain 18. CONCLUSIONS: FUTURE PERSPECTIVES Cannabinoid CB2 receptor ligands and their therapeutic potential in mental diseases Emmanuel S. Onaivi, Hiroki Ishiguro and Qing-Rong Liu
Authors
Liana Fattore Neuroscience Institute - Cagliari, National Research Council (CNR) - Italy.Liana Fattore is Senior Researcher at the Institute of Neuroscience, National Research Council of Italy (IN-CNR). She received a BSc in Biology in 1994, in Life Sciences in 1997 and a PhD in Neuroscience in 2003. From 2001 to 2002, she was Visiting Research Fellow at the Department of Experimental Psychology, University of Cambridge (UK).
She currently leads preclinical research on the neurobiology of drug abuse and behavioral dependences at the Department of Biomedical Sciences, Division of Neuroscience and Clinical Pharmacology, University of Cagliari, Italy. Her main fields of research focus primarily on addictive disorders, pathological dependences and behavioral dyscontrol, with special attention given to sex- and gender-dependent differences. Other research interests include neuropsychopharmacology, behavioral pharmacology, neurobiology of natural and drug reward, psychiatric disorders and comorbidity, new designer and internet drugs.
Dr. Fattore has (co)authored over 80 scientific peer-reviewed publications (research articles, reviews, commentaries, perspective articles, book chapters); she serves as referee for more than 20 International Journals and as external and independent Expert Evaluator of Research Project Proposals for several European Agencies.
She is Council Member of the Mediterranean Neuroscience Society (MNS) since 2012 and of the Italian Society of Neuroscience (SINS) since 2013. She heads the IN-CNR Laboratory of Behavioural Neuropharmacology in Cagliari that is home to young scientists from different backgrounds and academic levels wishing to experience a training period in behavioral neuroscience. She is strongly dedicated to increase awareness among high school students on the consequences of excessive drinking and substance abuse on health and brain functioning.
