Thomas' Hematopoietic Cell Transplantation. 2 Volume Set. 5th Edition

  • ID: 3110184
  • Book
  • 1416 Pages
  • John Wiley and Sons Ltd
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Fully revised, this outstanding reference on bone marrow transplantation is an essential, field–leading resource. In the past four decades, scientific progress in the area has led to an exponential increase in the number of transplant recipients worldwide, and this increase has been paralleled by impressive basic and applied research into the uses of haematopoietic stem cell transplantation. The content systemically covers the scientific basis for stem cell transplantation, patient–related issues, stem cell sources, complications of stem cell transplantation, and allogeneic and autologous transplantation for inherited diseases.

Divided into seven sections containing 106 chapters written by international experts, the fifth edition discusses the rapid expansion of the knowledge underlying transplantation biology, increased understanding of the complications of treatment, and new information related to the pathogenesis and treatment of diseases for which transplant is utilized. The edition also covers the expansion of donor options to provide stem cells and the genetic manipulation of both hematopoietic cells of the immune system. The fifth edition:

  • Features over 500 illustrations
  • Has been revised and updated throughout to take account of new and recent developments, from both a scientific and clinical perspective
  • Includes new chapters addressing basic science experiments in stem cell biology, immunology and tolerance
  • Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision–making.

Founding editor, E. Donnall Thomas MD, was a pioneer in stem cell research and won the 1990 Nobel Prize for his discoveries concerning organ and cell transplantation in the treatment of human diseases. In continuing this title, the Editors have produced a world–class resource for clinicians and researchers in the field of blood and bone marrow transplantation; hematologists and oncologists; transfusion medicine specialists; and medical staff working within transplant units and teams.

Now published in two volumes, the printed book includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more!

Praise for earlier editions:

"A must for the bookshelf of any person who has even the vaguest interest in the biology or practice of marrow, blood, or umbilical–cord hematopoietic stem–cell transplantation." New England Journal of Medicine

"Essential addition to the library of any unit performing bone marrow transplants."Journal of Hematotherapy

"Uniformly informative, helpful, well–organised and presented, comprehensive, up–to–date and well–referenced."British Journal of Haematology

"Overwhelmingly complete, extremely up–to–date and each chapter is written by a world leader in the field."Clinical and Laboratory Haematology

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Contributors, xi

Preface to the First Edition, xvii

Preface to the Fifth Edition, xviii

Tribute, xix

List of Abbreviations, xxii

Section 1: History and Use of Hematopoietic Cell Transplantation

1 A History of Allogeneic and Autologous Hematopoietic Cell Transplantation, 1Karl G. Blume and E. Donnall Thomas

2 Uses and Growth of Hematopoietic Cell Transplantation, 8Mary M. Horowitz

Section 2: Scientific Basis or Hematopoietic Cell Transplantation

Section 2a: Hematopoiesis and Stem Biology Transplantation

3 Generation of Definitive Engraftable Hematopoietic Stem Cells from Human Pluripotent Stem Cells, 16Laurence Dahéron and David T. Scadden

4 Hematopoietic Stem Cells, Regenerative Medicine, and Leukemogenesis, 25Irving Weissman

5 Marrow Microenvironment and Biology of Mobilization of Stem Cells, 50Michael P. Rettig, Mark A. Schroeder and John F. DiPersio

6 Expansion of Human Hematopoietic Stem Cells, 62Colleen Delaney

7 Mesenchymal Stromal Cells and Hematopoietic Cell Transplantation, 69Edwin M. Horwitz

8 Genetic Manipulation of Hematopoietic Stem Cells, 78Jennifer E. Adair, Grant D. Trobridge and Hans–Peter Kiem

Section 2b: Immunology

9 Overview of Hematopoietic Cell Transplantation Immunology, 96Paul J. Martin and Warren D. Shlomchik

10 Histocompatibility, 112Effie W. Petersdorf

11 Natural Killer Cells and Allogeneic Hematopoietic Cell Transplantation, 126Michael R. Verneris and Jeffrey S. Miller

12 Mechanisms of Tolerance, 136Defu Zeng and Samuel Strober

13 The Pathophysiology of Graft–versus–Host Disease, 146James L.M. Ferrara and Joseph H. Antin

14 Immune Regulation in Hematopoietic Cell Transplantation, 153Robert S. Negrin and Jerome Ritz

15 Immune Reconstitution Following Hematopoietic Cell Transplantation, 160Jarrod A. Dudakov, Miguel–Angel Perales and Marcel R.M. van den Brink

16 Biology of the Human Graft–versus–Tumor Response and How to Exploit It, 166Edus H. Warren

17 Dendritic Cells in Hematopoietic Cell Transplantation, 178Miriam Merad and Edgar G. Engleman

18 The Experimental Basis for Hematopoietic Cell Transplantation for Autoimmune Diseases, 191Judith A. Shizuru

Section 2c: Technical Aspects

19 Pharmacologic Basis for High–dose Chemotherapy, 211Borje S. Andersson, Benigno C. Valdez and Roy B. Jones

20 High–dose Preparatory Regimens, 223William I. Bensinger

21 Reduced–intensity Allogeneic Transplantation Regimens, 232Brenda M. Sandmaier and Rainer Storb

22 Radiotherapeutic Principles of Hematopoietic Cell Transplantation, 244Jeffrey Y.C. Wong and Timothy Schultheiss

23 Radioimmunotherapy and Hematopoietic Cell Transplantation, 258John M. Pagel and Ajay K. Gopal

24 Documentation of Engraftment and Characterization of Chimerism After Hematopoietic Cell Transplantation, 272Paul J. Martin

25 The Detection and Significance of Minimal Residual Disease, 281Merav Bar and Jerald P. Radich

26 Pathology of Hematopoietic Cell Transplantation, 292Keith R. Loeb, Cecilia C. Yeung and Howard M. Shulman

27 Biostatistical Methods in Hematopoietic Cell Transplantation, 329Joycelynne M. Palmer and Ted A. Gooley

28 Outcomes Research in Hematopoietic Cell Transplantation, 341Stephanie J. Lee

Section 3: Patient–oriented Issues in Hematopoietic Cell Transplantation

29 The Evaluation and Counseling of Candidates for Hematopoietic Cell Transplantation, 349Bart L. Scott and Brenda M. Sandmaier

30 Nursing Role in Hematopoietic Cell Transplantation, 362Rosemary C. Ford, Mihkaila M. Wickline and Diane Heye

31 Ethical Issues in Hematopoietic Cell Transplantation, 374David S. Snyder

32 Psychosocial Issues in Hematopoietic Cell Transplantation, 384Richard P. McQuellon and Katharine E. Duckworth

33 Assessment of Quality of Life in Hematopoietic Cell Transplantation Recipients, 392Karen L. Syrjala and Samantha Burns Artherholt

34 Sexuality Following Hematopoietic Cell Transplantation, 399D. Kathryn Tierney

35 Hematopoietic Cell Transplantation: The Patient′s Perspective, 407Susan K. Stewart

Section 4: Sources of Hematopoietic Cell for Hematopoietic Cell Transplantation

36 Hematopoietic Cell Procurement, Processing, and Transplantation: Standards, Accreditation, and Regulation, 414Phyllis I. Warkentin and Elizabeth J. Shpall

37 Bone Marrow and Peripheral Blood Cell Donors and Donor Registries, 423Dennis L. Confer, John P. Miller and Jeffrey W. Chell

38 The Role of the Transplant Program in a Nuclear Accident or Terrorism, 431Nelson J. Chao and Dennis L. Confer

39 Cord Blood Hematopoietic Cell Transplantation, 437Hal E. Broxmeyer, Sherif S. Farag and Vanderson Rocha

40 Mobilization of Peripheral Blood Hematopoietic Cells for Autologous HCT, 452Thomas C. Shea and John F. DiPersio

41 Peripheral Blood Hematopoietic Cells for Allogeneic Transplantation, 460Norbert Schmitz and Peter Dreger

42 Cryopreservation of Hematopoietic Cells, 469Scott D. Rowley

43 Use of Recombinant Growth Factors after Hematopoietic Cell Transplantation, 480Jürgen Finke and Roland Mertelsmann

44 Hematopoietic Cell Transplantation from Human Leukocyte Antigen Partially Matched Related Donors, 489Claudio Anasetti, Franco Aversa and Andrea Velardi

45 Hematopoietic Cell Transplantation from Unrelated Donors, 505Effie W. Petersdorf

Section 5: Hematopoietic Cell Transplantation for Acquired Disease

46 Hematopoietic Cell Transplantation for Aplastic Anemia, 517George E. Georges and Rainer Storb

47 Hematopoietic Cell Transplantation for Paroxysmal Nocturnal Hemoglobinuria, 537Ryotaro Nakamura

48 Hematopoietic Stem Cell Transplantation for Chronic Myeloid Leukemia, 545Jerald P. Radich and Ravi Bhatia

49 Hematopoietic Cell Transplantation for Juvenile Myelomonocytic Leukemia, 554Charlotte M. Niemeyer and Franco Locatelli

50 Hematopoietic Cell Transplantation for Adult Acute Myeloid Leukemia, 563Frederick R. Appelbaum

51 Hematopoietic Cell Transplantation for Childhood Acute Myeloid Leukemia, 576Michael A. Pulsipher, Meghann McManus and Soheil Meshinchi

52 Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia in Adults, 588Stephen J. Forman

53 Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia in Children, 600Parinda A. Mehta and Stella M. Davies

54 Hematopoietic Cell Transplantation for Myelodysplastic Syndromes and Myeloproliferative Neoplasms, 613H. Joachim Deeg

55 Hematopoietic Cell Transplantation for Multiple Myeloma, 625Amrita Krishnan and Sergio A. Giralt

56 Hematopoietic Cell Transplantation for Hodgkin Disease, 636Philip J. Bierman and Auayporn Nademanee

57 Hematopoietic Cell Transplantation for Non–Hodgkin Lymphoma (B Cell), 653Leslie L. Popplewell and Ginna G. Laport

58 Hematopoietic Cell Transplantation for Non–Hodgkin Lymphoma (T Cell), 664Jasmine Zain and Sandra H. Thomas

59 Hematopoietic Cell Transplantation for Chronic Lymphocytic Leukemia, 675Aaron C. Logan and David B. Miklos

60 Autologous Hematopoietic Cell Transplantation for Systemic Light Chain (AL–) Amyloidosis, 685Heather J. Landau, Morie A. Gertz and Raymond L. Comenzo

61 Autologous Hematopoietic Cell Transplantation for Breast Cancer and Germ–cell Tumors, 700Yago Nieto and Elizabeth J. Shpall

62 Hematopoietic Cell Transplantation for Renal Cell Carcinoma and Other Solid Tumors, 709Richard W. Childs and Ramaprasad Srinivasan

63 Hematopoietic Cell Transplantation for Neuroblastoma, 721Justin T. Wahlstrom and Katherine K. Matthay

64 Hematopoietic Cell Transplantation for Other Pediatric Solid Tumors, 729Masanori Hayashi, David M. Loeb and Allen R. Chen

65 Hematopoietic Cell Therapy for Human Immunodeficiency Virus Infection, 742Amrita Krishnan, Joseph Alvarnas, John J. Rossi and John A. Zaia

66 Hematopoietic Cell Transplantation for Autoimmune Diseases, 753Richard A. Nash

67 Hematopoietic Cell Transplantation for Rare Hematologic Malignancies, 765Vinod Pullarkat and Stephen J. Forman

68 Adoptive T–cell Therapy for Viral Disease in the Setting of Hematopoietic Cell Transplantation, 777Catherine M. Bollard and Helen E. Heslop

69 Adoptive T–cell Therapy for Malignancy in the Setting of Hematopoietic Cell Transplantation, 787Stephen J. Forman, Michael Kalos and Carl H. June

70 Relapse of Hematologic Malignancy After Allogeneic Hematopoietic Transplantation, 797Richard Champlin

Section 6: Hematopoietic Cell Transplantation for Inherited Disease

71 Hematopoietic Cell Transplantation for Thalassemia, 803Guido Lucarelli and Javid Gaziev

72 Hematopoietic Cell Transplantation for Sickle Cell Disease, 814Mark C. Walters

73 Hematopoietic Cell Transplantation for Immunodeficiency Diseases, 827Richard J. O′Reilly and Wilhelm Friedrich

74 Hematopoietic Cell Transplantation for Storage Diseases, 846Joseph Rosenthal

75 Hematopoietic Cell Transplantation for Macrophage, Granulocyte and Osteoclast, Disorders, 871Rajni Agarwal

76 Hematopoietic Cell Transplantation for Fanconi Anemia, 884John E. Wagner, Jakub Tolar, Arleen D. Auerbach and Margaret L. MacMillan

Section 7: Complications of Hematopoietic Cell Transplantation

77 Mechanisms and Treatment of Graft Failure, 905Robert Lowsky and Hans Messner

78 Blood Group Incompatibilities and Hemolytic Complications of Hematopoietic Cell Transplantation, 916Margaret R. O′Donnell

79 Principles of Transfusion Support Before and After Hematopoietic Cell Transplantation, 922Jeffrey McCullough

80 Vascular Access and Complications, 937I. Benjamin Paz

81 Pharmacologic Prevention of Acute Graft–versus–Host Disease, 951Nelson J. Chao

82 T–cell Depletion to Prevent Graft–versus–Host Disease, 965Robert J. Soiffer

83 Manifestations and Treatment of Acute Graft–versus–Host Disease, 973Corey Cutler and Joseph H. Antin

84 Chronic Graft–versus–Host Disease Clinical Manifestations and Therapy, 981Paul A. Carpenter, Mary E.D. Flowers and Steven Z. Pavletic

85 Bacterial Infections, 999Helen L. Leather and John R. Wingard

86 Fungal Infections After Hematopoietic Cell Transplantation, 1018Kieren A. Marr

87 Cytomegalovirus Infection, 1030John A. Zaia

88 Herpes Simplex Virus Infections, 1039Sanjeet S. Dadwal and James I. Ito

89 Varicella Zoster Virus Infections, 1046Dora Y. Ho and Ann M. Arvin

90 Epstein Barr Virus Infection, 1066Jennifer A. Kanakry and Richard F. Ambinder

91 Respiratory Viruses After Hematopoietic Cell Transplantation, 1073Sachiko Seo and Michael Boeckh

92 HHV–6A, HHV–6B, HHV–7, and HHV–8 After Hematopoietic Cell Transplantation, 1083Per Ljungman, Tetsushi Yoshikawa and Katherine N. Ward

93 Human Adenovirus, Polyomavirus, and Parvovirus Infections in Patients Undergoing Hematopoietic Stem Cell Transplantation, 1090Hans H. Hirsch and Steven A. Pergam

94 Gastrointestinal and Hepatic Complications, 1101David M. Hockenbery, Simone I. Strasser and George B. McDonald

95 Lung Injury Following Hematopoietic Cell Transplantation, 1117Kenneth R. Cooke and Gregory A. Yanik

96 Kidney and Bladder Complications of Hematopoietic Cell Transplantation, 1131Sangeeta Hingorani

97 Endocrine Complications Following Hematopoietic Cell Transplantation, 1142Fouad R. Kandeel and Behrouz Salehian

98 Common Potential Drug Interactions Following Hematopoietic Cell Transplantation, 1167Anne Poon and Lowan K. Ly

99 Nutrition Support of the Hematopoietic Cell Transplant Recipient, 1177Paula Charuhas Macris and Kerry K. McMillen

100 Pain Management, 1186Noelle V. Frey and Jonathan R. Gavrin

101 Oral Complications of Hematopoietic Cell Transplantation, 1203Mark M. Schubert, Maria Elvira Pizzigatti Correa and Douglas E. Peterson

102 Growth and Development After Hematopoietic Cell Transplantation, 1218K. Scott Baker and Anna Petryk

103 Delayed Non–malignant Complications After Hematopoietic Cell Transplantation, 1227Smita Bhatia

104 Subsequent Malignant Neoplasms After Hematopoietic Cell Transplantation, 1236Smita Bhatia and Ravi Bhatia

105 Neurologic Complications of Hematopoietic Cell Transplantation, 1248Harry Openshaw and Bihong T. Chen

106 Vaccination of Allogeneic and Autologous Hematopoietic Cell Recipients, 1258Trudy N. Small

Index, 1266

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Stephen J. Forman, MD Chair, Department of Hematology and Hematopoietic Cell Transplantation City of Hope Comprehensive Cancer Center Duarte, CA, USA

Robert S. Negrin, MD Professor of Medicine Chief, Division of Blood and Marrow Transplantation Stanford University Stanford, CA, USA

Joseph H. Antin, MD Professor of Medicine, Harvard Medical School Chief, Stem Cell Transplantation Dana–Farber/Brigham and Women′s Cancer Center Boston, MA, USA

Frederick R. Appelbaum, MD Member and Director, Clinical Research Division Fred Hutchinson Cancer Research Center Professor and Head, Division of Medical Oncology University of Washington School of Medicine Seattle, WA, USA

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