Translational Research in Coronary Artery Disease

  • ID: 3336065
  • Book
  • 244 Pages
  • Elsevier Science and Technology
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Translational Research in Coronary Artery Disease: Pathophysiology to Treatment covers the entire spectrum of basic science, genetics, drug treatment, and interventions for coronary artery disease. With an emphasis on vascular biology, this reference fully explains the fundamental aspects of coronary artery disease pathophysiology.

Included are important topics, including endothelial function, endothelial injury, and endothelial repair in various disease states, vascular smooth muscle function and its interaction with the endothelium, and the interrelationship between inflammatory biology and vascular function.

By providing this synthesis of current research literature, this reference allows the cardiovascular scientist and practitioner to access everything they need from one source.

  • Provides a concise summary of recent developments in coronary and vascular research, including previously unpublished data
  • Summarizes in-depth discussions of the pathobiology and novel treatment strategies for coronary artery disease
  • Provides access to an accompanying website that contains photos and videos of noninvasive diagnostic modalities for evaluation of coronary artery disease

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Chapter 1: Endothelial Biology
the role of endothelial cells and endothelial progenitor cells
Chapter 2: The Role of Vascular Smooth Muscle Phenotype and Cytochrome P450-Derived Eicosanoids in Coronary Artery Disease
Chapter 3: Inflammation and Coronary Artery Disease
Chapter 4: Adiponectin: A mediator of obesity, insulin resistance, diabetes and the metabolic syndrome
Chapter 5: Use of Stem Cells in Ischemic Heart Disease
Chapter 6: Vasculogenesis and Angiogenesis
Chapter 7: Lipids
Chapter 8: Genetics and Coronary Disease
Chapter 9: Nitric Oxide and Heart Failure in the Presence of Coronary Disease
Chapter 10: Revascularization for Silent Myocardial Ischemia
Chapter 11: Noninvasive Diagnostic Modalities for Evaluation of Coronary Artery Disease
Chapter 12: Current Approaches to Treatment of Ventricular Arrhythmias in Patients with Coronary Artery Disease
Chapter 13: Magnetic Resonance Imaging for Clinical Use and Research Investigation in Coronary Artery Disease
Chapter 14: Invasive Diagnostic Assessment of Coronary Artery Disease
Chapter 15: Drug Treatment of Coronary Artery Disease
Chapter 16: Percutaneous Coronary Intervention of Coronary Artery Disease
Chapter 17: Current Topics in Bypass Surgery
Chapter 18: Peripheral Venoarterial Extracorporeal Membrane Oxygenation for Treatment of Ischemic Shock
Chapter 19: Biostatistics Used for Clinical Investigation of Coronary Artery Disease
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Aronow, Wilbert S.
Wilbert S. Aronow, MD, is Professor of Medicine in the Cardiology Division at Westchester Medical Center and New York Medical College in Valhalla, New York, USA. Dr. Aronow received his MD from Harvard Medical School. He has edited 14 books and is author or coauthor of 1,545 papers or book chapters, 374 commentaries, 46 Letters to the Editor, and 1,068 abstracts and is presenter or copresenter of 1,431 talks at meetings. Dr. Aronow is a Fellow of the ACC, the AHA, the ACP, the ASPC, the AGS (Founding Fellow of Western Section), and the GSA. He has been a member of 152 editorial boards of medical journals, editor-in-chief of 4 journals, co-editor of 2 journals, deputy editor of 1 journal, executive editor of 2 journals, associate editor for 9 journals, and guest editor for 7 other medical journals. He has received each year from 2001-2016 an outstanding teacher and researcher award from the medical residents and from 2001-2016 from the cardiology fellows at Westchester Medical Center. He has received awards from the Society of Geriatric Cardiology, the Gerontological Society of America, New York Medical College including the 2014 Chancellor's Research Award, the F1000 Faculty Member of the Year Award for the Faculty of Cardiovascular Disorders in 2011, 2013, 2014, and 2015, the Walter Bleifeld Memorial Award for distinguished contributions to clinical research from the International Academy of Cardiology in 2010, and a Distinguished Fellowship Award from the International Academy of Cardiology in 2012. He has been a member of 4 national guidelines committees including being a coauthor of the 2010 AMDA guidelines for heart failure, co-chair and first author of the 2011 ACC/AHA expert consensus document on hypertension in the elderly, a coauthor of the 2015 AHA/ACC/ASH scientific statement on treatment of hypertension in patients with coronary artery disease, and is currently a member of the 2017 ACC/AHA/ AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the management of patients with hypertension.
McClung, John Arthur
John Arthur McClung has been on the faculty of New York Medical College since 1979. He is board certified in Internal Medicine, Cardiovascular Disease, and Echocardiography and currently serves as the Director of the Cardiovascular Fellowship Training Program as well as the Director of the Noninvasive Cardiology Laboratory at the Westchester Medical Center. He is a member of A?A and is a past Councilor for the New York State Chapter of the American College of Cardiology where he served as the chair of its nominating committee. In 1990, Dr. McClung founded Division of Clinical Ethics of the Department of Medicine at New York Medical College and served as its chief until 1995. He has published articles on ethical issues in the areas of cardiopulmonary resuscitation, bioethics consultation, and end of life care and is a frequent contributor to publications in the field of cardiovascular disease.
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