Biotechnology Reagents - Global Strategic Business Report

I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations I-1
Disclaimers I-2
Data Interpretation & Reporting Level I-3
Quantitative Techniques & Analytics I-3
Product Definitions and Scope of Study I-3
Cell & Tissue Culture Reagents I-4
DNA Synthesis & Sequencing Reagents I-4
Electrophoresis Reagents I-4
Flow Cytometry Reagents I-4
Immunoassay Reagents I-5
Liquid Chromatography Reagents I-5
PCR Reagents I-5
Protein Synthesis & Sequencing Reagents I-5

II. Executive Summary

1. OUTLOOK II-1
Reagents Market Players Witness Paradigm Shift II-1

2. MARKET DYNAMICS II-2
Highly Automated Instrumentation Restricts Use of Reagents II-2
Software-Intensive Nature and High System Complexity Impedes
Use of Automated Instruments II-2
Demand for Diverse Products Spurs Growth II-2
Increasing Use in Industrial Sector II-2
Molecular Biology and Protein Synthesis Reagents - the Fastest
Growing Segments II-3
Obtaining Data from Enzyme Functions II-3
New Economy Sees the Entry of Directed Evolution Enzymes II-3

3. BIOTECHNOLOGY - INDUSTRY OVERVIEW II-4
Growing by Leaps and Bounds II-4
Human Genome Mapping - A Colossal Milestone II-4
High Growth Applications Spur Industry Growth II-5
Biochips- Promising Future II-5
Convergence of Distinct Technologies II-6
Growing Collaboration between Biotech and Pharma Companies II-6

4. PRODUCT OVERVIEW II-7
A. Classification II-7
i. DNA Synthesis & Sequencing Reagents II-7
DNA: The Basis for Modern Biotechnology II-7
ii. PCR Reagents II-7
iii. Protein Synthesis & Sequencing Reagents II-7
iv. Electrophoresis Reagents II-8
v. Bio/Chemiluminescence Reagents II-8
vi. Immunoassay Reagents II-8
Antibodies II-8
Monoclonal and Polyclonal Antibodies II-8
Types of Monoclonal Antibodies II-8
a. Murine Monoclonal Antibodies II-8
b. Human Antibodies II-8
c. Chimeric Antibodies II-9
d. Bispecific Antibodies II-9
Hematology/Coagulation Reagents II-9
vii. Chromatography Reagents II-9
viii. Flow Cytometry Reagents II-9
ix. Cell & Tissue Culture Reagents II-9

5. PRODUCT INNOVATIONS/INTRODUCTIONS II-11
iCyt Introduces Synergy and Eclipse Flow Cytometry Products II-11
Millipore Unveils Luminata™ HRP Detection Reagents II-11
Agilent Technologies Introduces Advanced PCR Reagents II-12
InVitria Unveils Zap-Hybridoma II-12
Dionex Releases Reagent-Free Ion Chromatography system II-12
Aurora Releases PCR Fluorescent Probing Diagnostic Reagent Kits II-13
Applied Biosystems Launches Acoustic Focusing Cytometer II-13
BD Biosciences Unveils BD Kaleidoscope Reagent II-14
Advancell Launches Isocyp-Tox™ Cellular Reagent II-14
Applied Biosystems Introduces Latest Genetic Analyzers Lines II-14
Kollodis BioSciences Launches MAPTrix® ECM Range of Reagents II-15
Thermo Fisher Scientific Unveils FILLit™ Software II-15
Kapa Biosystems Rolls Out KAPA2G™ Fast HotStart DNA Polymerase II-15
DuPont Releases DuPont™ PCR Reagent Kits II-16
Applied Biosystems Unveils Sequencing-Based Tools for Whole
Transcriptomes II-16

6. PRODUCT INNOVATIONS/LAUNCHES - A HISTORIC PERSPECTIVE BUILDER II-18
454 Life Sciences Rolls Out GS FLX Titanium Range of Software
and Agents II-18
Trinity Biotech Introduces New Lyme Products in Europe II-18
Stratagene Launches Quantitative PCR Reagents II-18
Thermo Fisher Introduces Non-Serum Medium for Adherent CHO Cells II-19
Accuri Introduces Advanced Accuri C6 Flow Cytometer™ System II-19
Invitrogen Introduces In-Vivo RNAi Delivery Reagent II-20
Invitrogen Introduces Stem Cell Culture Services II-20
Beckman Coulter Introduces Two IOTest® Reagents II-20
Applied Biosystems Announces New Reagents II-21
Calypte Biomedical Introduces New Calypte Life Sciences Family
of Products II-22
Applied Biosystems Launches TaqMan® Cells-to-CT™ Kit Solutions II-22
Applied Biosystems Launches iTRAQ® Reagents II-22
PerkinElmer Launches Series 275 HRes™ LC System II-23
Sigma-Aldrich Introduces Imprint™ ChIP Kit II-23
Stratagene Introduces Expanded QPCR, QRT-PCR Reagents Line II-23
Asuragen Introduces Signature® LTx in Markets Worldwide II-23
Biomatrica Launches PCRboost™ - A New Reagent II-24
Genetix Group Launches New CytoGenetix FISH Kits and Reagents II-24
Strategic Diagnostics Introduces New Online Catalog of
Antibody Reagents II-25
Bioatlas Expands Bioatlas Product Lineup with Atlas Antifade II-25
ScienceXperts & Invitrogen Develop Flow Cytometry Software II-25
Beckman Coulter Launches Cell Signal Transduction Reagents II-25
Sigma-Aldrich Launches LentiExpress™ Technology II-26
Abbott Unveils New Assays and Reagents II-26
Applied Biosystems Introduces New Master Mix Reagent II-26
Promega Designs Advanced Luciferase Assay II-26
Ortho-Clinical Diagnostics Expands Test-Base for Infectious
Diseases II-27
Genetix Launches Two Novel CloneMedia Semi-Solid Media
Products II-27
Invitrogen Launches Lipofectamine LTX II-27
Beckman Coulter Launches IOTest® Anti-Rat Flow Cytometry Reagents II-28
EMD Biosciences Introduces ProteoPlex® Human Angiogenesis Array II-28
AspenBio Pharma Launches New Single-Chain Gonadotropin II-28
Ortho-Clinical Diagnostics Launches VITROS® Chemistry Products
d%A1c Reagent II-28
Beckman Coulter to Launch Access DHEA-S II-29
Solulink Introduces ChromaLink II-29
Cambrex Launches Versalinx Reagents II-29
Kreatech Unveils a New Range of Isolation and Labeling Kits II-29
Nanogen Launches Enterovirus Analyte Specific Reagent - MGB
Alert™ II-29
Olympus Unveils New Reagent Kit with Single Molecular
Fluorescence Spectroscopy II-29
SAFC Releases Proligo Reagents II-30
LI-COR Biosciences Releases New IRDye® Western Kits for
Odyssey® System II-30
Altor Launches STAR™ Multimer Reagents II-30
Guava Technologies Launches a New Range of Antibody Reagents II-30
Solexa Launches Genome Analysis System II-30
Daiichi Unveils New Reagent Kit II-30
Beckman Coulter Introduces Cellular Research Reagents II-31
ReaMetrix Introduces Accuford II-31
TriPath Imaging Unveils ProEx C II-31
Roche and 454 Life Sciences Launches Genome Sequencer 20
System and Reagents II-31
Chinese Academy of Military Medical Sciences Introduces
Reagent to Test Drug Resistance of HBV II-31
SIAL Unveils SYBR Green Extract-N-Amp Tissue PCR Kit II-31
Aldrich Introduces LAB Reagents II-32
Kreatech Rolls Out RNA ampULSe Amplification and Labeling Kits II-32
bioMérieux Launches NucliSens miniMAG and NucliSens Magnetic
Extraction Reagents II-32

7. RECENT INDUSTRY ACTIVITY II-33
Danaher Acquires Beckman Coulter II-33
Merck Acquires Millipore II-33
Accuri Cytometers and eBioscience Sign Global Partnership
Agreement II-34
Thermo Fisher Scientific to Acquire Fermentas II-34
Leica Microsystems Completes Genetix Acquisition II-35
Blue Sky Biotech Collaborates with Protein Attachment
Technologies II-35
AnaSpec Announces Distributor Agreement with Yope Biotechnology II-35
Commonwealth Biotechnologies Inks Agreement with Wise Century
Group II-36
Millipore Acquires Guava II-36
Idaho Technology and Kapa Biosystems Ink Licensing Agreement II-36
ChanTest Takes Over ACS II-37
CBI Divests Genetic and Bio-Analytical Testing Business to
Bostwick II-37
Eurogentec to Acquire AnaSpec Inc II-37
Merck Acquires BGIP II-38
Akron Biotech Merges with AppliChem II-38
Fisher HealthCare Inks Distribution Agreement with Dako II-38
PerkinElmer Enters into Agreement with BioLegend II-39
Premier Purchasing Partners and Helena Laboratories Sign
Agreement II-39

8. STRATEGIC CORPORATE DEVELOPMENTS - A HISTORIC PERSPECTIVE BUILDER II-40
Invitrogen and Applied Biosystems Merge to Form Life Technologies II-40
Affymetrix Takes Over Panomics II-40
Thermo Fisher Takes Over Affinity BioReagents II-40
Carna Biosciences Enters into Supply Agreement with Caliper
Life Sciences II-40
Affymetrix Acquires USB Corporation II-41
FASgen and Tetracore Ink Collaboration Agreement II-41
Prodesse and Quidel Ink a Co-Commercialization Agreement II-41
Bexion and MTTI to Collaborate for New Nanovesicle II-42
BD Acquires Cytopeia II-42
Affymetrix Acquires USB II-42
Millipore and Guava Technologies Enter into Collaboration II-42
Hologic Agrees to Acquire Third Wave II-43
Spartan Bioscience and TrimGen Enter into Partnership II-43
Multispan & Promega to Co-Develop Assay Tools II-44
STEMCELL Joins Forces with Geron II-44
HistoRx Signs Agreement with Eli Lilly II-44
GE Healthcare to Take Over Whatman II-45
Inverness Takes Over BBI II-45
Medical Solutions to Take Over Autogen II-45
Sysmex and bioMerieux Agree to Establish a Joint Venture II-45
Miltenyi Acquires Medic II-46
China Medical Acquires Beijing Bio-Ekon II-46
Gene Bridges Partners with Mbiotech II-46
Roche Acquires Ventana Medical II-46
BioMérieux to Shutdown Boxtel Facility II-47
Abbott Inks Agreement with Premier II-47
Beckman Coulter Acquires Dako's Flow Cytometry Instrumentation
Business II-47
Cliniqa Acquires the Assets of Reagents Applications II-47
Frontier Scientific Acquires Echelon Biosciences II-48
Immucor Signs Supply Agreement with American Red Cross II-48
Ventana Medical Takes Over Spring BioScience II-48
TriLink Biotechnologies Inks Agreement with Applied Biosystems II-49
Bio-Rad Takes Over DiaMed Holdings II-49
PerkinElmer Takes Over ViaCell II-49
Sigma-Aldrich in Alliance with Sangamo BioSciences II-49
Fitzgerald Industries Takes Over Cortex Biochem's
Immunoreagent Business II-50
Agilent Technologies Acquires Stratagene II-50
Dendritic Signs Supply Agreement with EMD Biosciences II-50
Spectral Diagnostics Inks Agreement with Bio-Rad II-51
Japanese Atol Plans to Acquire a Major Stake in Naha Yakuhin II-51
Roche Takes Over NimbleGen II-51
Roche Takes Over BioVeris II-51
Roche Acquires 454 Life Sciences II-52
Sysmex & Roche Diagnostics Extend Distribution Agreement II-52
Invitrogen and Biocon Inks Exclusive Marketing Agreement II-52
PerkinElmer Acquires Remaining Stake in PerkinElmer India II-52
Promega Enters Into Alliance with Guangzhou Institute II-53
Adaltis Acquires Shanghai Hua Tai Biotechnology II-53
ABR-Affinity Inks Distribution Agreements with Genesis & Good
Biotech II-53
The PLSG Makes Financial Investment in AIT II-54
Numira Merges with Visual Influence II-54
Abbott Receives FDA Clearance for CELL-DYN Ruby™ II-54
Tm Bioscience Bags Supply Contract JMC II-55
ReaMetrix Receives Clearance for Accuford Tri-T Stat II-55
Panomics Establishes New Subsidiary in Europe II-55
Promega Completes Benitec Acquisition II-55
NCGC Joins Forces with PerkinElmer II-55
MBL Acquires Antibody Business of LifeSpan BioSciences II-56
Sigma-Aldrich and Genospectra Sign a Series of Agreements II-56
Nitragin Completes the Acquisition of Agribiotics II-56
Fujirebio Diagnostics Acquires CanAg Diagnostics II-57
Chemicon Inks an Agreement with ASCC II-57
Takara Bio. Pharma Acquires Stakes in Takara Biotechnology II-57
Millipore Takes Over Serologicals II-57
Serologicals Takes Over LINCO II-57
Genospectra Merges with Panomics II-58
Roche Enters into Three-Year Contract with Premier II-58
KREATECH and GenTel Enter into Distribution Agreement II-58
Kreatech Enters into Supply Agreement with QIAGEN II-58
Invitrogen to Provide Reagents for Genome Sequencing of Solexa II-58
VWR International to Market Biocare Equipment and Reagents in IHC II-59
Biocare Partners with Epitomics for Reagents II-59
GE and CytoGenix Form an Alliance II-59
Fisher Biosciences Joins Forces with Dyomics II-59
PerkinElmer Partners with NCGC II-59
SAFC-Biosciences Formed to Support Sigma-Aldrich II-60
Takara Bio Takes Over Clontech II-60
Technes Subsidiary Pockets BiosPacific and Fortron Bio Science II-60
QIAGEN Obtains Nextal II-60
Invitrogen Takes Over Caltag II-60
Invitrogen Takes Over Biosource International II-60
Serologicals Acquires Specialty Media from Sentigen II-61
Invitrogen Acquires Zymed Laboratories II-61
Biotage Acquires Argonaut Technologies II-61
Invitrogen Acquires Dynal Biotech II-61
Vita and Cortex Biochem Enter into Distribution Agreement II-61
SIAL and OXB Sign an Agreement for Commercializing LentiVector
Technology II-61
Funakoshi and Affibody Sign a Distribution Agreement II-62
KREATECH and GenTel Enter into Marketing Agreement II-62
KREATECH and Ambion Enter into Supply Agreement II-62
SIAL Enters into Distribution Agreement with MedAssets II-62
IBT Signs Distribution Contracts for Enzymes II-62
Epitome Signs a License Agreement with EMD Biosciences II-63
Consorta Inks Multiple Agreements with Dade Behring II-63
SCS and Chemicon Sign an Agreement for ES Cell Media II-63
LSBC and BioCatalytics Enter into Collaborative Agreement for
Producing Enzymes II-63
Chemicon International Enters into an Agreement with QDC II-63
Dharmacon Signs an Agreement with Genentech II-64
Invitrogen Partners with PerkinElmer II-64
Chemicon and Axordia Collaborate for New Antibody Markers II-64
eGene Enters into Strategic Alliance with Transgenomic II-64
Cancer Genetics Selects Genetics Specialities II-65
Clinical Data Bags Distribution Rights for Hematology
Analyzers and Reagents II-65
BD Biosciences to Expand Production in Puerto Rico II-65
Olympus Enlarges R&D Unit in Ireland II-65
Olympus Begins Production of Immunoassay Reagents II-65
Koon-wah Leong, Shery Guo and Suyue Qian Produces Multilayer
Test Strips II-65
CMT Sells off Specialty Media Division II-65
CSL Divests Cell Culture Reagent Business to Sigma-Aldrich II-66
BD Divests Clontech Business II-66

9. FOCUS ON SELECT PLAYERS WORLDWIDE II-67
Abbott Diagnostics (USA) II-67
Beckman Coulter, Inc. (USA) II-67
Becton Dickinson and Company (USA) II-68
BioMérieux SA (France) II-68
EMD Biosciences, Inc. (USA) II-68
EMD Millipore Corporation (USA) II-68
Fitzgerald Industries International (USA) II-69
GE Healthcare (UK) II-69
Life Technologies Corp. (USA) II-70
Ortho-Clinical Diagnostics (USA) II-70
PerkinElmer, Inc. (USA) II-70
Promega Corp. (USA) II-71
Roche Diagnostics Ltd. (Switzerland) II-71
Siemens Healthcare Diagnostics, Inc. (USA) II-71
Sigma - Aldrich (USA) II-72

10. GLOBAL MARKET PERSPECTIVE II-73
Table 1: World Recent Past, Current & Future Market Analysis
for Biotechnology Reagents by Geographic Region - US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan) and Latin
America Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) II-73

Table 2: World Historic Review for Biotechnology Reagents by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan) and Latin America Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2003
through 2008 (includes corresponding Graph/Chart) II-74

Table 3: World 15-Year Perspective for Biotechnology Reagents
by Geographic Region - Percentage Breakdown of Dollar Sales
for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan)
and Latin America Markets for Years 2003, 2011 & 2017
(includes corresponding Graph/Chart) II-75
World Market for Biotechnology Reagents by Product Segment II-76
Table 4: World Recent Past, Current & Future Market Analysis
for Cell / Tissue Culture Reagents by Geographic Region - US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan) and
Latin America Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) II-76

Table 5: World Historic Review for Cell / Tissue Culture
Reagents by Geographic Region - US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan) and Latin America Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2003 through 2008 (includes corresponding Graph/Chart) II-77

Table 6: World 15-Year Perspective for Cell / Tissue Culture
Reagents by Geographic Region - Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia- Pacific (excluding
Japan) and Latin America Markets for Years 2003, 2011 & 2017
(includes corresponding Graph/Chart) II-78

Table 7: World Recent Past, Current & Future Market Analysis
for DNA Sequencing / Synthesis Reagents by Geographic Region -
US, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and
Latin America Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) II-79

Table 8: World Historic Review for DNA Sequencing / Synthesis
Reagents by Geographic Region - US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan) and Latin America Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2003 through 2008 (includes corresponding Graph/Chart) II-80

Table 9: World 15-Year Perspective for DNA Sequencing /
Synthesis Reagents by Geographic Region - Percentage Breakdown
of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan) and Latin America Markets for Years 2003,
2011 & 2017 (includes corresponding Graph/Chart) II-81

Table 10: World Recent Past, Current & Future Market Analysis
for Electrophoresis Reagents by Geographic Region - US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan) and
Latin America Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) II-82

Table 11: World Historic Review for Electrophoresis Reagents
by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan) and Latin America Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2003
through 2008 (includes corresponding Graph/Chart) II-83

Table 12: World 15-Year Perspective for Electrophoresis
Reagents by Geographic Region - Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan) and Latin America Markets for Years 2003, 2011 & 2017
(includes corresponding Graph/Chart) II-84

Table 13: World Recent Past, Current & Future Market Analysis
for Flow Cytometry Reagents by Geographic Region - US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan) and Latin
America Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) II-85

Table 14: World Historic Review for Flow Cytometry Reagents by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan) and Latin America Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2003
through 2008 (includes corresponding Graph/Chart) II-86

Table 15: World 15-Year Perspective for Flow Cytometry
Reagents by Geographic Region - Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan) and Latin America Markets for Years 2003, 2011 & 2017
(includes corresponding Graph/Chart) II-87

Table 16: World Recent Past, Current & Future Market Analysis
for Immunoassay Reagents by Geographic Region - US, Canada,
Japan, Europe, Asia-Pacific (excluding Japan) and Latin
America Independently Analyzed with Annual Sales Figures in
US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) II-88

Table 17: World Historic Review for Immunoassay Reagents by
Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan) and Latin America Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2003
through 2008 (includes corresponding Graph/Chart) II-89

Table 18: World 15-Year Perspective for Immunoassay Reagents
by Geographic Region - Percentage Breakdown of Dollar Sales
for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan)
and Latin America Markets for Years 2003, 2011 & 2017
(includes corresponding Graph/Chart) II-90

Table 19: World Recent Past, Current & Future Market Analysis
for Liquid Chromatography Reagents by Geographic Region - US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan) and
Latin America Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) II-91

Table 20: World Historic Review for Liquid Chromatography
Reagents by Geographic Region - US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan) and Latin America Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2003 through 2008 (includes corresponding Graph/Chart) II-92

Table 21: World 15-Year Perspective for Liquid Chromatography
Reagents by Geographic Region - Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan) and Latin America Markets for Years 2003, 2011 & 2017
(includes corresponding Graph/Chart) II-93

Table 22: World Recent Past, Current & Future Market Analysis
for Polymerase Chain Reaction Reagents by Geographic Region -
US, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and
Latin America Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) II-94

Table 23: World Historic Review for Polymerase Chain Reaction
Reagents by Geographic Region - US, Canada, Japan, Europe,
Asia-Pacific (excluding Japan) and Latin America Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2003 through 2008 (includes corresponding Graph/Chart) II-95

Table 24: World 15-Year Perspective for Polymerase Chain
Reaction Reagents by Geographic Region - Percentage Breakdown
of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan) and Latin America Markets for Years 2003,
2011 & 2017 (includes corresponding Graph/Chart) II-96

Table 25: World Recent Past, Current & Future Market Analysis
for Protein Synthesis Reagents by Geographic Region - US,
Canada, Japan, Europe, Asia-Pacific (excluding Japan) and
Latin America Independently Analyzed with Annual Sales Figures
in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) II-97

Table 26: World Historic Review for Protein Synthesis Reagents
by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific
(excluding Japan) and Latin America Independently Analyzed
with Annual Sales Figures in US$ Million for Years 2003
through 2008 (includes corresponding Graph/Chart) II-98

Table 27: World 15-Year Perspective for Protein Synthesis
Reagents by Geographic Region - Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding
Japan) and Latin America Markets for Years 2003, 2011 & 2017
(includes corresponding Graph/Chart) II-99

III. MARKET

1. THE UNITED STATES III-1
A.Market Analysis III-1
Biotech Industry in the US III-1
Escalating Demand for Biomedical Research Reagents and Kits III-1
Application-Oriented Products Herald a Technological Upheaval III-1
Competition - Highly Prevalent III-1
Review of US Cell/Tissue Culture Supplies Market III-2
Industrial Segment - Largest End-User III-2
Rise in Cell Culture Equipment Demand Leads to Innovation III-3
Factors Influencing the Market for Media III-3
Fetal Bovine Serum - Use on a Decline III-3
Table 28: Leading Producers of Fetal Bovine Serum in the
US (2011): Percentage Breakdown of Value Sales for Life
Technologies, Thermo Scientific (Hyclone), and Others
(includes corresponding Graph/Chart) III-3
Suppliers Searching for New Areas III-3
Serum Free Products Market: Rapidly Growing III-4
Immunoassay Reagents III-4
Table 29: Leading Players in the US Immunoassay Reagents
Market (2011): Percentage Breakdown of Value Sales for
Abbott Diagnostics, Siemens, Roche Diagnostics, Beckman
Coulter, and Others (includes corresponding Graph/Chart) III-4
Issues Affecting the US Immunodiagnostics Market III-4
Technological Innovations Play a Vital Role III-5
Chromatography Reagents Market to Register Steady Growth III-5
Table 30: US Market for Chromatography Reagents (2011):
Percentage Breakdown of Sales of Reagents by Application/
Technique) (includes corresponding Graph/Chart) III-5
Molecular Biological Reagents III-6
Rapidly Growing Market III-6
Table 31: Molecular Biology Reagents Market in the US
(2011): Percentage Breakdown of Value Sales by End use for
Academic User, Biotech industry, Pharmaceuticals, and
Government (includes corresponding Graph/Chart) III-6
DNA Sequencing: Gaining Prominence III-6
B.Market Analytics III-7
Table 32: The US Recent Past, Current & Future Analysis for
Biotechnology Reagents by Product Segment - Cell/Tissue
Culture Reagents, DNA Sequencing/Synthesis Reagents,
Electrophoresis Reagents, Flow Cytometry Reagents,
Immunoassay Reagents, Liquid Chromatography Reagents,
Polymerase Chain Reaction Reagents, and Protein Synthesis
Reagents Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) III-7

Table 33: The US Historic Review for Biotechnology Reagents
by Product Segment - Cell/Tissue Culture Reagents, DNA
Sequencing/ Synthesis Reagents, Electrophoresis Reagents,
Flow Cytometry Reagents, Immunoassay Reagents, Liquid
Chromatography Reagents, Polymerase Chain Reaction Reagents,
and Protein Synthesis Reagents Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2003 through 2008 (includes corresponding Graph/Chart) III-8

Table 34: The US 15-Year Perspective for Biotechnology
Reagents by Product Segment - Percentage Breakdown of Dollar
Sales for Cell/Tissue Culture Reagents, DNA Sequencing/
Synthesis Reagents, Electrophoresis Reagents, Flow Cytometry
Reagents, Immunoassay Reagents, Liquid Chromatography
Reagents, Polymerase Chain Reaction Reagents, and Protein
Synthesis Reagents Markets for 2003, 2011 & 2017 (includes
corresponding Graph/Chart) III-9

2. CANADA III-10
A.Market Analysis III-10
Biotech Sector in Canada III-10
Outlook III-10
B.Market Analytics III-11
Table 35: Canadian Recent Past, Current & Future Analysis
for Biotechnology Reagents by Product Segment - Cell/Tissue
Culture Reagents, DNA Sequencing/Synthesis Reagents,
Electrophoresis Reagents, Flow Cytometry Reagents,
Immunoassay Reagents, Liquid Chromatography Reagents,
Polymerase Chain Reaction Reagents, and Protein Synthesis
Reagents Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) III-11

Table 36: Canadian Historic Review for Biotechnology
Reagents by Product Segment - Cell/Tissue Culture Reagents,
DNA Sequencing/ Synthesis Reagents, Electrophoresis
Reagents, Flow Cytometry Reagents, Immunoassay Reagents,
Liquid Chromatography Reagents, Polymerase Chain Reaction
Reagents, and Protein Synthesis Reagents Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2003 through 2008 (includes corresponding
Graph/Chart) III-12

Table 37: Canadian 15-Year Perspective for Biotechnology
Reagents by Product Segment - Percentage Breakdown of Dollar
Sales for Cell/Tissue Culture Reagents, DNA Sequencing/
Synthesis Reagents, Electrophoresis Reagents, Flow Cytometry
Reagents, Immunoassay Reagents, Liquid Chromatography
Reagents, Polymerase Chain Reaction Reagents, and Protein
Synthesis Reagents Markets for 2003, 2011 & 2017 (includes
corresponding Graph/Chart) III-13

3. JAPAN III-14
A.Market Analysis III-14
Biotech Scenario III-14
Outlook III-15
Table 38: Japanese Market for Biotechnology (2011):
Percentage Breakdown of Revenues by End-Use Application -
Medical Care, Food, Bio Tools & Information, Environment &
Energy, and Others (includes corresponding Graph/Chart) III-15
B.Market Analytics III-16
Table 39: Japanese Recent Past, Current & Future Analysis
for Biotechnology Reagents by Product Segment - Cell/Tissue
Culture Reagents, DNA Sequencing/Synthesis Reagents,
Electrophoresis Reagents, Flow Cytometry Reagents,
Immunoassay Reagents, Liquid Chromatography Reagents,
Polymerase Chain Reaction Reagents, and Protein Synthesis
Reagents Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) III-16

Table 40: Japanese Historic Review for Biotechnology
Reagents by Product Segment - Cell/Tissue Culture Reagents,
DNA Sequencing/ Synthesis Reagents, Electrophoresis
Reagents, Flow Cytometry Reagents, Immunoassay Reagents,
Liquid Chromatography Reagents, Polymerase Chain Reaction
Reagents, and Protein Synthesis Reagents Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2003 through 2008 (includes corresponding
Graph/Chart) III-17

Table 41: Japanese 15-Year Perspective for Biotechnology
Reagents by Product Segment - Percentage Breakdown of Dollar
Sales for Cell/Tissue Culture Reagents, DNA Sequencing/
Synthesis Reagents, Electrophoresis Reagents, Flow Cytometry
Reagents, Immunoassay Reagents, Liquid Chromatography
Reagents, Polymerase Chain Reaction Reagents, and Protein
Synthesis Reagents Markets for 2003, 2011 & 2017 (includes
corresponding Graph/Chart) III-18

4. EUROPE III-19
A.Market Analysis III-19
Biotechnology in Europe on an Expansion Spree III-19
PCR Technology - An Overview III-19
Technological Advancements Drive PCR Market III-19
B.Market Analytics III-20
Table 42: European Recent Past, Current & Future Analysis
for Biotechnology Reagents by Geographic Region - France,
Germany, Italy, UK, and Rest of Europe Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2009 through 2017 (includes corresponding Graph/Chart) III-20

Table 43: European Historic Review for Biotechnology
Reagents by Geographic Region - France, Germany, Italy, UK,
and Rest of Europe Markets Independently Analyzed with
Annual Sales Figures in US$ Million for Years 2003 through
2008 (includes corresponding Graph/Chart) III-21

Table 44: European 15-Year Perspective for Biotechnology
Reagents by Product Segment - Percentage Breakdown of Dollar
Sales for France, Germany, Italy, UK, and Rest of Europe for
Years 2003, 2011 & 2017 (includes corresponding Graph/Chart) III-22

Table 45: European Recent Past, Current & Future Analysis
for Biotechnology Reagents by Product Segment - Cell/Tissue
Culture Reagents, DNA Sequencing/Synthesis Reagents,
Electrophoresis Reagents, Flow Cytometry Reagents,
Immunoassay Reagents, Liquid Chromatography Reagents,
Polymerase Chain Reaction Reagents, and Protein Synthesis
Reagents Markets for Years 2009 through 2017 (includes
corresponding Graph/Chart) III-23

Table 46: European Historic Review for Biotechnology
Reagents by Product Segment - Cell/Tissue Culture Reagents,
DNA Sequencing/ Synthesis Reagents, Electrophoresis
Reagents, Flow Cytometry Reagents, Immunoassay Reagents,
Liquid Chromatography Reagents, Polymerase Chain Reaction
Reagents, and Protein Synthesis Reagents Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2003 through 2008 (includes corresponding
Graph/Chart) III-24

Table 47: European 15-Year Perspective for Biotechnology
Reagents by Product Segment - Percentage Breakdown of Dollar
Sales for Cell/ Tissue Culture Reagents, DNA Sequencing/
Synthesis Reagents, Electrophoresis Reagents, Flow Cytometry
Reagents, Immunoassay Reagents, Liquid Chromatography
Reagents, Polymerase Chain Reaction Reagents, and Protein
Synthesis Reagents Markets for Years 2003, 2011 & 2017
(includes corresponding Graph/Chart) III-25

4a. FRANCE III-26
Market Analytics III-26
Table 48: French Recent Past, Current & Future Analysis for
Biotechnology Reagents by Product Segment - Cell/ Tissue
Culture Reagents, DNA Sequencing/Synthesis Reagents,
Electrophoresis Reagents, Flow Cytometry Reagents,
Immunoassay Reagents, Liquid Chromatography Reagents,
Polymerase Chain Reaction Reagents, and Protein Synthesis
Reagents Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) III-26

Table 49: French Historic Review for Biotechnology Reagents
by Product Segment - Cell/Tissue Culture Reagents, DNA
Sequencing/ Synthesis Reagents, Electrophoresis Reagents,
Flow Cytometry Reagents, Immunoassay Reagents, Liquid
Chromatography Reagents, Polymerase Chain Reaction Reagents,
and Protein Synthesis Reagents Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2003 through 2008 (includes corresponding Graph/Chart) III-27

Table 50: French 15-Year Perspective for Biotechnology
Reagents by Product Segment - Percentage Breakdown of Dollar
Sales for Cell/Tissue Culture Reagents, DNA Sequencing/
Synthesis Reagents, Electrophoresis Reagents, Flow Cytometry
Reagents, Immunoassay Reagents, Liquid Chromatography
Reagents, Polymerase Chain Reaction Reagents, and Protein
Synthesis Reagents Markets for Years 2003, 2011 & 2017
(includes corresponding Graph/Chart) III-28

4b. GERMANY III-29
A.Market Analysis III-29
German Biotech Industry in Retrospective III-29
Outlook III-29
B.Market Analytics III-30
Table 51: German Recent Past, Current & Future Analysis for
Biotechnology Reagents by Product Segment - Cell/ Tissue
Culture Reagents, DNA Sequencing/Synthesis Reagents,
Electrophoresis Reagents, Flow Cytometry Reagents,
Immunoassay Reagents, Liquid Chromatography Reagents,
Polymerase Chain Reaction Reagents, and Protein Synthesis
Reagents Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) III-30

Table 52: German Historic Review for Biotechnology Reagents
by Product Segment - Cell/Tissue Culture Reagents, DNA
Sequencing/ Synthesis Reagents, Electrophoresis Reagents,
Flow Cytometry Reagents, Immunoassay Reagents, Liquid
Chromatography Reagents, Polymerase Chain Reaction Reagents,
and Protein Synthesis Reagents Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2003 through 2008 (includes corresponding Graph/Chart) III-31

Table 53: German 15-Year Perspective for Biotechnology
Reagents by Product Segment - Percentage Breakdown of Dollar
Sales for Cell/ Tissue Culture Reagents, DNA Sequencing/
Synthesis Reagents, Electrophoresis Reagents, Flow Cytometry
Reagents, Immunoassay Reagents, Liquid Chromatography
Reagents, Polymerase Chain Reaction Reagents, and Protein
Synthesis Reagents Markets for Years 2003, 2011 & 2017
(includes corresponding Graph/Chart) III-32

4c. ITALY III-33
Market Analytics III-33
Table 54: Italian Recent Past, Current & Future Analysis for
Biotechnology Reagents by Product Segment - Cell/Tissue
Culture Reagents, DNA Sequencing/ Synthesis Reagents,
Electrophoresis Reagents, Flow Cytometry Reagents,
Immunoassay Reagents, Liquid Chromatography Reagents,
Polymerase Chain Reaction Reagents, and Protein Synthesis
Reagents Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) III-33

Table 55: Italian Historic Review for Biotechnology Reagents
by Product Segment - Cell/Tissue Culture Reagents, DNA
Sequencing/ Synthesis Reagents, Electrophoresis Reagents,
Flow Cytometry Reagents, Immunoassay Reagents, Liquid
Chromatography Reagents, Polymerase Chain Reaction Reagents,
and Protein Synthesis Reagents Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2003 through 2008 (includes corresponding Graph/Chart) III-34

Table 56: Italian 15-Year Perspective for Biotechnology
Reagents by Product Segment - Percentage Breakdown of Dollar
Sales for Cell/Tissue Culture Reagents, DNA Sequencing/
Synthesis Reagents, Electrophoresis Reagents, Flow Cytometry
Reagents, Immunoassay Reagents, Liquid Chromatography
Reagents, Polymerase Chain Reaction Reagents, and Protein
Synthesis Reagents Markets for Years 2003, 2011 & 2017
(includes corresponding Graph/Chart) III-35

4d. THE UNITED KINGDOM III-36
A.Market Analysis III-36
Research Entities III-36
Commercial Activities III-36
B.Market Analytics III-37
Table 57: The UK Recent Past, Current & Future Analysis for
Biotechnology Reagents by Product Segment - Cell/Tissue
Culture Reagents, DNA Sequencing/ Synthesis Reagents,
Electrophoresis Reagents, Flow Cytometry Reagents,
Immunoassay Reagents, Liquid Chromatography Reagents,
Polymerase Chain Reaction Reagents, and Protein Synthesis
Reagents Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) III-37

Table 58: The UK Historic Review for Biotechnology Reagents
by Product Segment - Cell/Tissue Culture Reagents, DNA
Sequencing/ Synthesis Reagents, Electrophoresis Reagents,
Flow Cytometry Reagents, Immunoassay Reagents, Liquid
Chromatography Reagents, Polymerase Chain Reaction Reagents,
and Protein Synthesis Reagents Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2003 through 2008 (includes corresponding Graph/Chart) III-38

Table 59: The UK 15-Year Perspective for Biotechnology
Reagents by Product Segment - Percentage Breakdown of Dollar
Sales for Cell/Tissue Culture Reagents, DNA Sequencing/
Synthesis Reagents, Electrophoresis Reagents, Flow Cytometry
Reagents, Immunoassay Reagents, Liquid Chromatography
Reagents, Polymerase Chain Reaction Reagents, and Protein
Synthesis Reagents Markets for Years 2003, 2011 & 2017
(includes corresponding Graph/Chart) III-39

4e. REST OF EUROPE III-40
A.Market Analysis III-40
Medical Device Market in Spain III-40
Russian Clinical Diagnostic Equipment and Supplies Market III-40
B.Market Analytics III-41
Table 60: Rest of Europe Market for Biotechnology Reagents -
Recent Past, Current & Future Analysis by Product Segment
for Cell/Tissue Culture Reagents, DNA Sequencing/Synthesis
Reagents, Electrophoresis Reagents, Flow Cytometry Reagents,
Immunoassay Reagents, Liquid Chromatography Reagents,
Polymerase Chain Reaction Reagents, and Protein Synthesis
Reagents Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) III-41

Table 61: Rest of Europe Historic Review for Biotechnology
Reagents by Product Segment - Cell/Tissue Culture Reagents,
DNA Sequencing/ Synthesis Reagents, Electrophoresis
Reagents, Flow Cytometry Reagents, Immunoassay Reagents,
Liquid Chromatography Reagents, Polymerase Chain Reaction
Reagents, and Protein Synthesis Reagents Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2003 through 2008 (includes corresponding
Graph/Chart) III-42

Table 62: Rest of Europe 15-Year Perspective for
Biotechnology Reagents by Product Segment - Percentage
Breakdown of Dollar Sales for Cell/Tissue Culture Reagents,
DNA Sequencing/ Synthesis Reagents, Electrophoresis
Reagents, Flow Cytometry Reagents, Immunoassay Reagents,
Liquid Chromatography Reagents, Polymerase Chain Reaction
Reagents, and Protein Synthesis Reagents Markets for Years
2003, 2011 & 2017 (includes corresponding Graph/Chart) III-43

5. ASIA-PACIFIC III-44
A.Market Analysis III-44
Biotechnology - A Burgeoning Market III-44
Impact of IPR on Biotechnology Market III-44
Asia-Pacific - A Lucrative R&D Base III-44
Focus on Key Biotechnology Markets III-45
India III-45
China III-45
Korea III-46
Clinical Lab Products Market in Korea III-46
B.Market Analytics III-47
Table 63: Asia-Pacific Market for Biotechnology Reagents -
Recent Past, Current & Future Analysis by Product Segment
for Cell/Tissue Culture Reagents, DNA Sequencing/Synthesis
Reagents, Electrophoresis Reagents, Flow Cytometry Reagents,
Immunoassay Reagents, Liquid Chromatography Reagents,
Polymerase Chain Reaction Reagents, and Protein Synthesis
Reagents Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) III-47

Table 64: Asia-Pacific Historic Review for Biotechnology
Reagents by Product Segment - Cell/Tissue Culture Reagents,
DNA Sequencing/ Synthesis Reagents, Electrophoresis
Reagents, Flow Cytometry Reagents, Immunoassay Reagents,
Liquid Chromatography Reagents, Polymerase Chain Reaction
Reagents, and Protein Synthesis Reagents Markets
Independently Analyzed with Annual Sales Figures in US$
Million for Years 2003 through 2008 (includes corresponding
Graph/Chart) III-48

Table 65: Asia-Pacific 15-Year Perspective for Biotechnology
Reagents by Product Segment - Percentage Breakdown of Dollar
Sales for Cell/Tissue Culture Reagents, DNA Sequencing/
Synthesis Reagents, Electrophoresis Reagents, Flow Cytometry
Reagents, Immunoassay Reagents, Liquid Chromatography
Reagents, Polymerase Chain Reaction Reagents, and Protein
Synthesis Reagents Markets for Years 2003, 2011 & 2017
(includes corresponding Graph/Chart) III-49

6. LATIN AMERICA III-50
A.Market Analysis III-50
The Brazilian Biotech Industry: An Overview III-50
Table 66: Biotechnology Industry in Brazil (2011):
Percentage Breakdown of Revenues Generated by State
(includes corresponding Graph/Chart) III-50

Table 67: Biotechnology Industry in Brazil (2011):
Percentage Breakdown by End-Use Sector - Human Health,
Government & International Biotechnology Companies,
Consumables Suppliers, Equipment, Agribusiness, Animal
Health, and Environment (includes corresponding
Graph/Chart) III-51
B.Market Analytics III-52
Table 68: Latin American Market for Biotechnology Reagents -
Recent Past, Current & Future Analysis by Product Segment
for Cell/Tissue Culture Reagents, DNA Sequencing/Synthesis
Reagents, Electrophoresis Reagents, Flow Cytometry Reagents,
Immunoassay Reagents, Liquid Chromatography Reagents,
Polymerase Chain Reaction Reagents, and Protein Synthesis
Reagents Markets Independently Analyzed with Annual Sales
Figures in US$ Million for Years 2009 through 2017 (includes
corresponding Graph/Chart) III-52

Table 69: Latin American Historic Review for Biotechnology
Reagents by Product Segment - Cell/Tissue Culture Reagents,
DNA Sequencing/Synthesis Reagents, Electrophoresis Reagents,
Flow Cytometry Reagents, Immunoassay Reagents, Liquid
Chromatography Reagents, Polymerase Chain Reaction Reagents,
and Protein Synthesis Reagents Markets Independently
Analyzed with Annual Sales Figures in US$ Million for Years
2003 through 2008 (includes corresponding Graph/Chart) III-53

Table 70: Latin American 15-Year Perspective for
Biotechnology Reagents by Product Segment - Percentage
Breakdown of Dollar Sales for Cell/Tissue Culture Reagents,
DNA Sequencing/ Synthesis Reagents, Electrophoresis
Reagents, Flow Cytometry Reagents, Immunoassay Reagents,
Liquid Chromatography Reagents, Polymerase Chain Reaction
Reagents, and Protein Synthesis Reagents Markets for Years
2003, 2011 & 2017 (includes corresponding Graph/Chart) III-54

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 267 (including Divisions/Subsidiaries - 324)

• -----------------------------------------

Region/Country Players

• -----------------------------------------

The United States 195
Canada 10
Japan 6
Europe 93
France 6
Germany 22
The United Kingdom 26
Italy 11
Spain 2
Rest of Europe 26
Asia-Pacific (Excluding Japan) 18
Latin America 2

• -----------------------------------------