This comprehensive and authoritative book discusses the critical role of the utero-placenta in neurodisability, both at term and preterm. It examines aspects of fetal compromise and possible cerebro-protective interventions, recent evidence on fetal growth and mental illness, as well as cerebro-therapeutics. Throughout the book, information from the basic sciences placed within the clinical context.
- Written by leading obstetricians, neonatologists, paediatricians and pathologists.
- Discusses the role of placenta in the pathophysiology of CNS
- Examines recent evidence of endocrine, haematological and inflammatory origins of utero-placental dysfunction
- Reviews latest advances in antepartum and perinatal imaging
Table of Contents
1. Placental pathology and perinatal brain injury
Raymond Redline
2. Abnormal Placental Phenotypes
Colin Sibley and Michelle Desforges
3. Aberrant placental endocrinology, fetal growth and neurodevelopment
Jayne Charnoc and Melissa Westwood
4. The rheology of utero-placental and feto-placental blood flow
Ian Crocker
5. Inflammation and Placentation
Karen Racicot and Gil Mor
6. Infections and the fetal inflammatory response
Donald Peebles and Catherine James
7. Cerebral ischaemia and white matter injury
Suresh Victor and Michael Weindling
8. In utero imaging of the human placenta
Emma Ingram and Ed Johnstone
9. Cerebral Function and Fetal Growth Restriction
Irene Cetin and Valentina Brusati
10. Placental programming and mental illness: fetal growth and schizophrenia
Kathryn Abel and Martin Allin
11. Cerebro-therapeutics
Philip Steer
12. Summing up and unsolved problems
Karin Nelson
