Klotho isthe latest edition of a series first published in 1943 on Vitamins and Hormones and the longest-running serial published by Academic Press. It provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic, with volumes focusing on a single molecule or on a disease that is related to vitamins or hormones that are interpreted broadly so that related substances, such as transmitters, cytokines, growth factors, and others can be reviewed.
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Table of Contents
1. Klotho-Related Protein KLrP: Structure and Functions Yasuhiro Hayashi and Makoto Ito 2. The FGF21 Receptor Signaling Complex: KLOTHO?, FGFR1c and Other Regulatory Interactions Dawn M. Kilkenny and Jonathan V. Rocheleau 3. Klotho-Dependent Cellular Transport Regulation Mentor Sopjani and Miribane Dërmaku-Sopjani 4. Klotho and the Growth Hormone/Insulin-like Growth Factor 1 Axis: Novel Insights Into Complex Interactions Tami Rubinek and Dalit Modan-Moses 5. Klotho Prevents Translocation of NF?B Paula Buendía, Rafael Ramírez, Pedro Aljama and Julia Carracedo 6. The FGF23/KLOTHO Regulatory Network and its Roles in Human Disorders Saori Kinoshita and Masanobu Kawai 7. MicroRNA-34a and Impaired FGF19/21 Signaling in Obesity Ting Fu and Jongsook Kim Kemper 8. The Role of Alpha-Klotho as a Universal Tumor Suppressor Tami Rubinek and Ido Wolf 9. Klotho is a Neuroprotective and Cognition-Enhancing Protein Carmela R. Abraham, Patrick C. Mullen, Tracey Tucker Zhou, Cidi Chen and Ella Zeldich 10. Function and Change with Aging of a-Klotho in the Kidney Keiko Akasaka-Manya, Hiroshi Manya and Tamao Endo 11. aKlotho and Chronic Kidney Disease Javier A. Neyra and Ming Chang Hu 12. Deficiency of Soluble a-Klotho as an Independent Cause of Uremic Cardiomyopathy Jian Xie, Yueh-Lin Wu and Chou-Long Huang
