Geography Covered
- Global coverage
HYPEROXALURIA Understanding
HYPEROXALURIA: Overview
Hyperoxaluria is a condition that occurs when there is too much oxalate in the urine. Oxalate is a natural chemical in body and also contained in some foods, is normally eliminated from the body through the kidneys in the urine. Symptoms of hyperoxaluria can develop anytime from infancy to later adulthood (over 70 years of age). The most common initial symptom is usually kidney stones. Urine tests, Blood tests and scans may contribute to the diagnosis of Hyperoxaluria. The goal of treatment is to lower the level of oxalate in the body and prevent calcium oxalate crystals from forming in the kidneys and other body tissues.HYPEROXALURIA - Pipeline Insight, 2024 report outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the HYPEROXALURIA pipeline landscape is provided which includes the disease overview and HYPEROXALURIA treatment guidelines. The assessment part of the report embraces, in depth HYPEROXALURIA commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, HYPEROXALURIA collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
The companies and academics are working to assess challenges and seek opportunities that could influence HYPEROXALURIA R&D. The therapies under development are focused on novel approaches to treat/improve HYPEROXALURIA.HYPEROXALURIA Emerging Drugs Chapters
This segment of the HYPEROXALURIA report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.HYPEROXALURIA Emerging Drugs
Oxabact: Oxa TheraOxalobacter formigenes is an anaerobe, non-pathogenic bacterium which exclusively uses oxalate as the energy source. OxThera has taken this bacterial strain isolated from the human gut and developed a live biotherapeutic product candidate. Oxabact is being studied in phase III stage of development for the treatment of primaryhyperoxaluria.Reloxiliase: Allen Pharmaceuticals Reloxaliase (formerly ALLN-177), is a first-in-class, non-absorbed, orally-administered enzyme for the treatment of hyperoxaluria. Reloxaliase, a crystalline formulation of the enzyme oxalate decarboxylase, has been designed to specifically degrade oxalate within the GI tract, thus limiting systemic absorption of oxalate into the bloodstream. Reloxiliase is being evaluated for the treatment of Hyperoxaluria in phase III stage of development.
Stiripentol: Biocodex Stiripentol is an orally active compound originated by Biocodex that inhibits several P450 cytochromes. Stiripentol developed by Biocodex is being studied in phase II stage of development for the treatment of primaryHyperoxluria.
HYPEROXALURIA: Therapeutic Assessment
This segment of the report provides insights about the different HYPEROXALURIA drugs segregated based on following parameters that define the scope of the report, such as:Major Players in HYPEROXALURIA
There are approx. 10+ key companies which are developing the therapies for HYPEROXALURIA. The companies which have their HYPEROXALURIA drug candidates in the most advanced stage, i.e. phase III include, OxaThera.Phases
This report covers around 10+ products under different phases of clinical development like- Late stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
Route of Administration
HYPEROXALURIA pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as- Oral
- Subcutaneous
- Intravenous
- Intramuscular
- Molecule Type
Products have been categorized under various Molecule types such as
- Bispecific Antibody
- Peptides
- Small molecule
- Gene therapy
- Product Type
HYPEROXALURIA: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses HYPEROXALURIA therapeutic drugs key players involved in developing key drugs.Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging HYPEROXALURIA drugs.HYPEROXALURIA Report Insights
- HYPEROXALURIA Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
HYPEROXALURIA Report Assessment
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Key Questions
Current Treatment Scenario and Emerging Therapies:- How many companies are developing HYPEROXALURIA drugs?
- How many Hyperoxaluria drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of HYPEROXALURIA?
- What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the HYPEROXALURIA therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for HYPEROXALURIA and their status?
- What are the key designations that have been granted to the emerging drugs?
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Table of Contents
Companies Mentioned (Partial List)
A selection of companies mentioned in this report includes, but is not limited to:
- OxThera
- Allen Pharmaceuticals
- Biocodex
- Alnylam Pharmaceuticals
- Chinook therapeutics
- Dicerna Pharmaceuticals, Inc.
- Synlogic
- Federation Bio