T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) - Pipeline Review, H1 2017

  • ID: 4311865
  • Report
  • 49 pages
  • Global Markets Direct
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FEATURED COMPANIES

  • Atox Bio Ltd
  • OSE Immunotherapeutics
  • TheraMAB LLC
  • MORE
T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) - Pipeline Review, H1 2017

Summary:

T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) - CD28 is a proteins expressed on T cells. It co-stimulates signals required for T cell activation and survival. It enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L co-stimulation.

T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) pipeline Target constitutes close to 8 molecules. Out of which approximately 8 molecules are developed by Companies. The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical and Discovery stages are 1, 2, 1, 2 and 2 respectively. Report covers products from therapy areas Immunology, Oncology, Central Nervous System, Dermatology, Gastrointestinal, Genito Urinary System And Sex Hormones, Metabolic Disorders, Musculoskeletal Disorders, Ophthalmology and Toxicology which include indications Graft Versus Host Disease (GVHD), Rheumatoid Arthritis, Systemic Lupus Erythematosus, Acute Renal Failure (ARF) (Acute Kidney Injury), Arthritis, B-Cell Chronic Lymphocytic Leukemia, Gastrointestinal Radiation Toxicity, Hypersensitivity, Kidney Transplant Rejection, Multiple Sclerosis, Pancreatitis, Plaque Psoriasis (Psoriasis Vulgaris), Psoriasis, Sicca Syndrome (Sjogren), Skin And Soft Tissue Infections, Solid Tumor, Type 1 Diabetes (Juvenile Diabetes) and Uveitis.

The latest report T Cell Specific Surface Glycoprotein CD28 - Pipeline Review, H1 2017, outlays comprehensive information on the T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviewsalso reviews key players involved in T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) targeted therapeutics development with respective active and dormant or discontinued projects.

The report is built using data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope:
  • The report provides a snapshot of the global therapeutic landscape for T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28)
  • The report reviews T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
  • The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
  • The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
  • The report reviews key players involved in T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) targeted therapeutics and enlists all their major and minor projects
  • The report assesses T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
  • The report summarizes all the dormant and discontinued pipeline projects
  • The report reviews latest news and deals related to T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) targeted therapeutics
Reasons to Buy:
  • Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
  • Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
  • Identify and understand the targeted therapy areas and indications for T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28)
  • Identify the use of drugs for target identification and drug repurposing
  • Identify potential new clients or partners in the target demographic
  • Develop strategic initiatives by understanding the focus areas of leading companies
  • Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
  • Devise corrective measures for pipeline projects by understanding T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) development landscape
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
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Note: Product cover images may vary from those shown
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FEATURED COMPANIES

  • Atox Bio Ltd
  • OSE Immunotherapeutics
  • TheraMAB LLC
  • MORE
  1. Introduction
  2. T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) - Overview
  3. T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) - Therapeutics Development
  4. Products under Development by Stage of Development
  5. Products under Development by Therapy Area
  6. Products under Development by Indication
  7. Products under Development by Companies
  8. T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) - Therapeutics Assessment
  9. Assessment by Mechanism of Action
  10. Assessment by Route of Administration
  11. Assessment by Molecule Type
  12. T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) - Companies Involved in Therapeutics Development
  13. Atox Bio Ltd
  14. Bristol-Myers Squibb Company
  15. Five Prime Therapeutics Inc
  16. OSE Immunotherapeutics
  17. TheraMAB LLC
  18. T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) - Drug Profiles
  19. ALPN-101 - Drug Profile
  20. Product Description
  21. Mechanism Of Action
  22. R&D Progress
  23. FPT-155 - Drug Profile
  24. Product Description
  25. Mechanism Of Action
  26. R&D Progress
  27. FR-104 - Drug Profile
  28. Product Description
  29. Mechanism Of Action
  30. R&D Progress
  31. lulizumab pegol - Drug Profile
  32. Product Description
  33. Mechanism Of Action
  34. R&D Progress
  35. Monoclonal Antibody to Agonize CD278 and CD28 for Oncology - Drug Profile
  36. Product Description
  37. Mechanism Of Action
  38. R&D Progress
  39. Recombinant Protein to Agonize CD278 and CD28 for Oncology - Drug Profile
  40. Product Description
  41. Mechanism Of Action
  42. R&D Progress
  43. reltecimod sodium - Drug Profile
  44. Product Description
  45. Mechanism Of Action
  46. R&D Progress
  47. TAB-08 - Drug Profile
  48. Product Description
  49. Mechanism Of Action
  50. R&D Progress
  51. T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) - Dormant Products
  52. T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) - Discontinued Products
  53. T Cell Specific Surface Glycoprotein CD28 (TP44 or CD28) - Product Development Milestones
  54. Featured News & Press Releases
  55. May 23, 2017: Atox Bios Reltecimod Passes Futility Analysis in Phase 3 ACCUTE Study; Trial Continues as Planned
  56. Nov 17, 2016: OSE Immunotherapeutics announces the online publication of positive Phase 1 clinical results with FR104 in the Journal of Immunology
  57. Nov 03, 2016: Atox Bio Announces Independent Safety Monitoring Committee Recommendation to Continue Phase 3 Study Of AB103 In Necrotizing Soft Tissue Infections
  58. Jun 15, 2016: Atox Bio Awarded Next Milestone-based Option by BARDA to Support Development of AB103 for Necrotizing Soft Tissue Infections
  59. Dec 07, 2015: Atox Bio Enrolls First Patient in Phase 3 Study of Potential Treatment for Necrotizing Soft Tissue Infection (Flesh Eating Bacteria)
  60. Jul 09, 2015: Effimune launches Phase I clinical trial on immune system regulation control
  61. Apr 15, 2015: Effimune obtains regulatory approval for Phase I clinical trial in humans of its new immunomodulator FR104
  62. Feb 12, 2015: Two major scientific articles validate Effimune’s drug candidate and reinforce the proof of concept of the technology aimed at regulating the immune system
  63. Dec 25, 2014: TheraMAB presents new clinical data on theralizumab (TAB08) at Nature Biotechnology
  64. Sep 29, 2014: Atox Bio Awarded Contract Worth up to $24 Million for the Development of AB103 by the Biomedical Advanced Research and Development Authority
  65. Aug 05, 2014: AB103 Granted Orphan Medicinal Product Designation in the European Union for the Treatment of Necrotizing Soft Tissue Infections
  66. Jan 14, 2014: TheraMAB announces initiation of Phase II clinical trial of mAb TABO8 for the treatment of Rheumatoid Arthritis
  67. Apr 09, 2013: Atox Bio Publishes Data Demonstrating Broad Therapeutic Effect Of Flagship Product In Treating Flesh Eating Bacteria
  68. Nov 20, 2012: Atox Bio Announces Positive Top-line Results In AB103 Necrotizing Soft Tissue Infections Phase IIa Trial
  69. Sep 10, 2012: Atox Bio’s AB103 Receives FDA Fast Track Designation For Treatment Of Necrotizing Soft Tissue Infections
  70. Appendix
  71. Methodology
  72. Coverage
  73. Secondary Research
  74. Primary Research
  75. Expert Panel Validation
  76. Contact Us
  77. Disclaimer
List of Tables:
  1. Number of Products under Development by Stage of Development, H1
  2. Number of Products under Development by Therapy Areas, H1
  3. Number of Products under Development by Indication, H1
  4. Number of Products under Development by Companies, H1
  5. Products under Development by Companies, H1
  6. Products under Development by Companies, H1 2017 (Contd..1), H1
  7. Number of Products by Stage and Mechanism of Actions, H1
  8. Number of Products by Stage and Route of Administration, H1
  9. Number of Products by Stage and Molecule Type, H1
  10. Pipeline by Atox Bio Ltd, H1
  11. Pipeline by Bristol-Myers Squibb Company, H1
  12. Pipeline by Five Prime Therapeutics Inc, H1
  13. Pipeline by OSE Immunotherapeutics, H1
  14. Pipeline by TheraMAB LLC, H1
  15. Dormant Projects, H1
  16. Discontinued Products, H1
List of Figures:
  1. Number of Products under Development by Stage of Development, H1
  2. Number of Products under Development by Therapy Areas, H1
  3. Number of Products under Development by Top 10 Indications, H1
  4. Number of Products by Mechanism of Actions, H1
  5. Number of Products by Stage and Mechanism of Actions, H1
  6. Number of Products by Routes of Administration, H1
  7. Number of Products by Stage and Routes of Administration, H1
  8. Number of Products by Molecule Types, H1
  9. Number of Products by Stage and Molecule Types, H1
Note: Product cover images may vary from those shown
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  • Atox Bio Ltd
  • Bristol-Myers Squibb Company
  • Five Prime Therapeutics Inc
  • OSE Immunotherapeutics
  • TheraMAB LLC
Note: Product cover images may vary from those shown
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Note: Product cover images may vary from those shown
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