Next-generation Sequencing: Emerging Clinical Applications and Global Markets

  • ID: 4327497
  • Report
  • Region: Global
  • 321 Pages
  • BCC Research
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until Jun 30th 2018
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The Global Clinical Next-Generation Sequencing (NGS) Market is Expected to Grow at a CAGR of 27%, from Nearly $3.2 Billion in 2017 to $10.5 Billion by 2022

FEATURED COMPANIES

  • 10X Genomics, Inc.
  • Caris Life Sciences
  • Envision Genomics
  • Helix Opco Llc
  • New Oncology Gmbh
  • Qiagen NV
  • MORE

Report Includes

  • An overview of the global market for next-generation sequencing and its emerging clinical applications.
  • Analyses of global market trends, with data from 2016, estimates for 2017, and projections of compound annual growth rates (CAGRs) through 2022.
  • Examination of the sequencing industry structure for key market segments.
  • Discussion covering the strategies employed by the main companies in the market.
  • Comprehensive company profiles of major players in the field.

Report Scope

The scope of the report includes clinical NGS technologies, applications, industries, initiatives, patents and companies. The markets for NGS-based diagnostics are given for the years 2015, 2016, 2017 and 2022.

This report reviews the main sequencing technologies and explains why genetic variation is important in clinical testing. It then discusses some of the significant research initiatives that impact clinical NGS applications. The main market driving forces are also discussed.

The report examines the markets by test complexity, clinical indication and test purpose. Test complexity refers to the plex level (i.e., the number of genetic markers that can be analyzed within a sample) and coverage (e.g., the extent to which the genome is covered) of the test. Examining the market by test complexity provides valuable insight into which products (e.g., sample preparation, NGS instrument, informatics, etc.) will be in demand in the future.

The report provides market data and forecasts for NGS diagnostics by specific applications, including those for cancer, cardiovascular diseases, clinical microbiology and infectious diseases, Mendelian disorders, metabolic and immune disorders, neurological disorders, reproductive health, and transplant medicine.

Specific geographic markets are discussed, including North America, Europe, Asia-Pacific, and the rest of the world.

Industry sectors analyzed include sequencing instruments, target enrichment, informatics, clinical laboratory testing services, reproductive health diagnostics, liquid biopsy, immune sequencing, HLA typing, third generation sequencing, and direct to consumer.

More than 200 companies in the clinical NGS industry are profiled in this report.

A summary of the main industry acquisitions and strategic alliances from 2015 through April 2017 are provided, including key alliance trends.

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FEATURED COMPANIES

  • 10X Genomics, Inc.
  • Caris Life Sciences
  • Envision Genomics
  • Helix Opco Llc
  • New Oncology Gmbh
  • Qiagen NV
  • MORE

1: Introduction

  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Scope of Report
  • Information Sources
  • Methodology
  • Geographic Breakdown

2: Summary and Highlights

  • Table 1 : Summary Table: Global Clinical Next-Generation Sequencing Market, by Disease Class, Through 2022
  • Figure 1 : Summary Figure: Global Clinical Next-Generation Sequencing Market, by Disease Class, 2015-2022

3: Overview

  • Introduction
  • Clinical NGS Markets
  • Clinical NGS Growth Driving Forces
  • Clinical NGS Applications
  • Clinical NGS Industry

4: Technology Background

  • Importance of DNA
  • Genetic Variation and Analysis
  • Genetic Analysis Technologies
  • Sequencing in Clinical Applications
  • Sequencing Technologies
  • Informatics Technologies
  • Clinical Sequencing Technology Challenges

5: Clinical NGS Initiatives

  • Clinical Next-Generation Sequencing Projects
  • Table 28 : Clinical Next-Generation Sequencing Projects

6: Clinical NGS Applications

  • Introduction
  • Cancer Applications
  • Mendelian Disorders Applications
  • Reproductive Health Applications
  • Microbiology and Infectious Disease Applications
  • Complex Disorders Applications

7: Clinical NGS Industry

  • Introduction
  • NGS Instrument Industry
  • Target Enrichment and Amplification Industry
  • NGS Clinical Informatics Industry
  • NGS Testing Services Industry
  • Reproductive Health Diagnostics Industry
  • Liquid Biopsy Industry
  • Immune Sequencing Industry
  • HLA Typing Industry
  • Third-Generation Sequencing Industry
  • Direct-to-Consumer Genetic Testing Industry

8: Acquisitions and Strategic Alliances

  • Acquisitions
  • Strategic Alliances

9: Clinical NGS Markets

  • Growth Driving Forces
  • Clinical Sequencing Market
  • Clinical NGS Cancer Market
  • NGS Cardiology Diagnostics Markets
  • NGS Mendelian Disorders Diagnostics Markets
  • NGS Metabolic/Immune Disorder Diagnostics Markets
  • NGS Neurology Diagnostics Markets
  • Reproductive Health Markets
  • NGS Microbiology and Infectious Disease Diagnostic Market
  • Transplant Market
  • Geographical Market

10: Patent Review

  • Clinical NGS Patents
  • Clinical NGS Patents by Indication
  • Cell-free DNA Patents
  • Sequencing-Related Patent Issues

11: Company Profiles

  • 3Billion Inc.
  • 10X Genomics, Inc.
  • 23Andme Inc.
  • Adaptive Biotechnologies Inc.
  • Admera Health
  • Agilent Technologies Inc.
  • Alcediag
  • Almac Group Ltd.
  • Amarantus Bioscience Holdings Inc.
  • Ambry Genetics
  • Aperiomics Inc.
  • Appistry Inc.
  • Arup Laboratories
  • Asuragen Inc.
  • Athena Diagnostics Inc.
  • Atreca Inc.
  • Base4 Innovation Ltd.
  • Baylor Miraca Genetics Laboratories Inc.
  • Becton, Dickinson And Co.
  • Bellwether Bio Inc.
  • Berry Genomics Co. Ltd.
  • Bgi Shenzhen
  • Bioarray S.L.
  • Biodesix Inc.
  • Biomarx Inc.
  • Bio-Rad Laboratories Inc.
  • Blueprint Genetics
  • Boreal Genomics
  • Cambridge Epigenetix Ltd.
  • Cancer Genetics
  • Caredx Inc.
  • Caris Life Sciences
  • Cegat Gmbh
  • Cellular Research Inc.
  • Celsee Diagnostics
  • Centogene AG
  • Cergentis BV
  • Chronix Biomedical
  • Circulogene Theranostics
  • Cirina
  • Claritas Genomics Inc.
  • Cofactor Genomics Inc.
  • Combimatrix Corporation
  • Color Genomics
  • Cooper Surgical Inc.
  • Coriell Life Sciences Inc.
  • Correlagen Diagnostics Inc.
  • Cosmosid
  • Counsyl Inc.
  • Courtagen Life Sciences Inc.
  • Cynvenio Biosystems Inc.
  • Cypher Genomics Inc.
  • Danaher Corp.
  • Darui Biotechnology Co. Ltd.
  • Depixus
  • Devyser AB
  • Diagnomics
  • Diploid
  • Directed Genomics Llc
  • Dna Electronics Ltd.
  • Dnanexus Inc.
  • Edico Genome
  • Electronic Biosciences
  • Envision Genomics
  • Epic Sciences
  • Esperite NV
  • Eurofins Genomics
  • Exact Sciences Corporation
  • Exosome Diagnostics Inc.
  • Foundation Medicine Inc.
  • Freenome Inc.
  • Full Genomes Corporation
  • Fusion Genomics Corporation
  • Gatc Biotech AG
  • Genapsys Inc.
  • Gendx BV
  • Gene By Gene Ltd.
  • Genedx Inc.
  • Genepeeks Inc.
  • Genomatix Software Gmbh
  • Genome.One Pty Ltd
  • Genomic Expression
  • Genomic Health Inc.
  • Genome Profiling Llc.
  • Genomnia Srl
  • Genomoncology
  • Genospace
  • Gigagen Inc.
  • Good Start Genetics Inc.
  • Golden Helix
  • Grail
  • Grandomics Biosciences Co. Ltd.
  • Guardant Health Inc.
  • Guardiome
  • Helix Opco Llc
  • Histogenetics Llc.
  • Htg Molecular Diagnostics Inc.
  • Human Longevity Inc.
  • Illumina Inc.
  • Inex Innovations Exchange Pte Ltd
  • Interpace Diagnostics Llc.
  • Invitae
  • Invivoscribe Inc.
  • Irepertoire Inc.
  • Kailos Genetics
  • Karius Inc.
  • Kellbenx Inc.
  • Kew Group Inc.
  • Kingmed Diagnostics Center Co. Ltd.
  • Laboratory Corporation Of America Inc.
  • Laboratory For Molecular Medicine
  • Lasergen Inc.
  • Leucine Rich Bio Pvt. Ltd.
  • Lumenogix Inc.
  • Macrogen Inc.
  • Mapmygenome
  • Maverix Biomics Inc.
  • Mayo Medical Laboratories
  • Medgenome Labs Pvt. Ltd.
  • Medomics Llc.
  • Merck KGAA
  • Mirati Therapeutics
  • Mogene LC
  • Molecular Health Gmbh
  • Molecularmd Corp.
  • Mriglobal Research Institute
  • Myriad Genetics Inc.
  • Nanostring Technologies Inc.
  • Natera Inc.
  • Neogenomics Inc.
  • New England Biolabs
  • Newgene Ltd.
  • New Oncology Gmbh
  • Nipd Genetics
  • N-Of-One Inc.
  • Novartis AG
  • Novogene Corporation
  • Nugen Technologies Inc.
  • Omicia Inc.
  • Omixon Biocomputing KFT
  • Omniseq Llc.
  • Oncodna SA
  • Oncospire Genomics
  • Oneome Inc.
  • Oxford Gene Technology
  • Oxford Nanopore Technologies Ltd.
  • Pacific Biosciences Of California Inc.
  • Pairnomix Inc.
  • Parabase Genomics
  • Paradigm Diagnostics Inc
  • Parseq Lab S.R.O.
  • Pathway Genomics Corporation
  • Perkinelmer Inc.
  • Personal Genome Diagnostics Inc.
  • Personalis Inc.
  • Pieriandx
  • Population Genetics Technologies Ltd.
  • Portable Genomics Llc
  • Positive Bioscience
  • Predicine Inc.
  • Premaitha Health Plc
  • Prenetics
  • Pressure Biosciences Inc.
  • Preventiongenetics Inc.
  • Qiagen NV
  • Quantapore Inc.
  • Quantum Biosystems Inc.
  • Quantumdx
  • Quest Diagnostics Inc.
  • Real Time Genomics Inc.
  • Resolution Bioscience Inc.
  • Roche Holding AG
  • Sequencing.Com
  • Seven Bridges Genomics Inc.
  • Sistemas Genómicos Sl
  • Softgenetics Llc
  • Sophia Genetics
  • Spera Medical
  • Station X Inc.
  • Strand Life Sciences Pvt. Ltd.
  • Stratec Biomedical AG
  • Stratos Genomics Inc.
  • Supratech Micropath Laboratory & Research Institute Pvt. Ltd.
  • Sure Genomics Inc.
  • Syapse
  • Symbiodx
  • Thermo Fisher Scientific Inc.
  • Transgenomic Inc.
  • Trovagene Inc.
  • Two Pore Guys Inc.
  • Ubiquity Genomics Inc.
  • Vela Diagnostics
  • Wafergen Bio-Systems Inc.
  • Warp Drive Bio Llc.
  • Xcell Biosciences Inc.
  • Yikon Genomics Co. Ltd.
  • Zhejiang Dian Diagnostics Co. Ltd.
  • Zixin Pharmaceutical Industrial Co, Ltd.
  • ZS Genetics Inc.
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FEATURED COMPANIES

  • 10X Genomics, Inc.
  • Caris Life Sciences
  • Envision Genomics
  • Helix Opco Llc
  • New Oncology Gmbh
  • Qiagen NV
  • MORE

Analyst Credentials:

John Bergin has held business development, sales and marketing positions with a Fortune 500 advanced materials company, as well as executive management positions with a nanotechnology/separations company. Bergin holds a B.S. degree in Chemistry, an M.S. degree in Biotechnology and a Master of Business Administration. John Bergin is a pseudonym of the author.

Note: Product cover images may vary from those shown
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  • 3Billion Inc.
  • 10X Genomics, Inc.
  • 23Andme Inc.
  • Adaptive Biotechnologies Inc.
  • Admera Health
  • Agilent Technologies Inc.
  • Alcediag
  • Almac Group Ltd.
  • Amarantus Bioscience Holdings Inc.
  • Ambry Genetics
  • Aperiomics Inc.
  • Appistry Inc.
  • Arup Laboratories
  • Asuragen Inc.
  • Athena Diagnostics Inc.
  • Atreca Inc.
  • Base4 Innovation Ltd.
  • Baylor Miraca Genetics Laboratories Inc.
  • Becton, Dickinson And Co.
  • Bellwether Bio Inc.
  • Berry Genomics Co. Ltd.
  • Bgi Shenzhen
  • Bioarray S.L.
  • Biodesix Inc.
  • Biomarx Inc.
  • Bio-Rad Laboratories Inc.
  • Blueprint Genetics
  • Boreal Genomics
  • Cambridge Epigenetix Ltd.
  • Cancer Genetics
  • Caredx Inc.
  • Caris Life Sciences
  • Cegat Gmbh
  • Cellular Research Inc.
  • Celsee Diagnostics
  • Centogene AG
  • Cergentis BV
  • Chronix Biomedical
  • Circulogene Theranostics
  • Cirina
  • Claritas Genomics Inc.
  • Cofactor Genomics Inc.
  • Combimatrix Corporation
  • Color Genomics
  • Cooper Surgical Inc.
  • Coriell Life Sciences Inc.
  • Correlagen Diagnostics Inc.
  • Cosmosid
  • Counsyl Inc.
  • Courtagen Life Sciences Inc.
  • Cynvenio Biosystems Inc.
  • Cypher Genomics Inc.
  • Danaher Corp.
  • Darui Biotechnology Co. Ltd.
  • Depixus
  • Devyser AB
  • Diagnomics
  • Diploid
  • Directed Genomics Llc
  • Dna Electronics Ltd.
  • Dnanexus Inc.
  • Edico Genome
  • Electronic Biosciences
  • Envision Genomics
  • Epic Sciences
  • Esperite NV
  • Eurofins Genomics
  • Exact Sciences Corporation
  • Exosome Diagnostics Inc.
  • Foundation Medicine Inc.
  • Freenome Inc.
  • Full Genomes Corporation
  • Fusion Genomics Corporation
  • Gatc Biotech AG
  • Genapsys Inc.
  • Gendx BV
  • Gene By Gene Ltd.
  • Genedx Inc.
  • Genepeeks Inc.
  • Genomatix Software Gmbh
  • Genome.One Pty Ltd
  • Genomic Expression
  • Genomic Health Inc.
  • Genome Profiling Llc.
  • Genomnia Srl
  • Genomoncology
  • Genospace
  • Gigagen Inc.
  • Good Start Genetics Inc.
  • Golden Helix
  • Grail
  • Grandomics Biosciences Co. Ltd.
  • Guardant Health Inc.
  • Guardiome
  • Helix Opco Llc
  • Histogenetics Llc.
  • Htg Molecular Diagnostics Inc.
  • Human Longevity Inc.
  • Illumina Inc.
  • Inex Innovations Exchange Pte Ltd
  • Interpace Diagnostics Llc.
  • Invitae
  • Invivoscribe Inc.
  • Irepertoire Inc.
  • Kailos Genetics
  • Karius Inc.
  • Kellbenx Inc.
  • Kew Group Inc.
  • Kingmed Diagnostics Center Co. Ltd.
  • Laboratory Corporation Of America Inc.
  • Laboratory For Molecular Medicine
  • Lasergen Inc.
  • Leucine Rich Bio Pvt. Ltd.
  • Lumenogix Inc.
  • Macrogen Inc.
  • Mapmygenome
  • Maverix Biomics Inc.
  • Mayo Medical Laboratories
  • Medgenome Labs Pvt. Ltd.
  • Medomics Llc.
  • Merck KGAA
  • Mirati Therapeutics
  • Mogene LC
  • Molecular Health Gmbh
  • Molecularmd Corp.
  • Mriglobal Research Institute
  • Myriad Genetics Inc.
  • Nanostring Technologies Inc.
  • Natera Inc.
  • Neogenomics Inc.
  • New England Biolabs
  • Newgene Ltd.
  • New Oncology Gmbh
  • Nipd Genetics
  • N-Of-One Inc.
  • Novartis AG
  • Novogene Corporation
  • Nugen Technologies Inc.
  • Omicia Inc.
  • Omixon Biocomputing KFT
  • Omniseq Llc.
  • Oncodna SA
  • Oncospire Genomics
  • Oneome Inc.
  • Oxford Gene Technology
  • Oxford Nanopore Technologies Ltd.
  • Pacific Biosciences Of California Inc.
  • Pairnomix Inc.
  • Parabase Genomics
  • Paradigm Diagnostics Inc
  • Parseq Lab S.R.O.
  • Pathway Genomics Corporation
  • Perkinelmer Inc.
  • Personal Genome Diagnostics Inc.
  • Personalis Inc.
  • Pieriandx
  • Population Genetics Technologies Ltd.
  • Portable Genomics Llc
  • Positive Bioscience
  • Predicine Inc.
  • Premaitha Health Plc
  • Prenetics
  • Pressure Biosciences Inc.
  • Preventiongenetics Inc.
  • Qiagen NV
  • Quantapore Inc.
  • Quantum Biosystems Inc.
  • Quantumdx
  • Quest Diagnostics Inc.
  • Real Time Genomics Inc.
  • Resolution Bioscience Inc.
  • Roche Holding AG
  • Sequencing.Com
  • Seven Bridges Genomics Inc.
  • Sistemas Genómicos Sl
  • Softgenetics Llc
  • Sophia Genetics
  • Spera Medical
  • Station X Inc.
  • Strand Life Sciences Pvt. Ltd.
  • Stratec Biomedical AG
  • Stratos Genomics Inc.
  • Supratech Micropath Laboratory & Research Institute Pvt. Ltd.
  • Sure Genomics Inc.
  • Syapse
  • Symbiodx
  • Thermo Fisher Scientific Inc.
  • Transgenomic Inc.
  • Trovagene Inc.
  • Two Pore Guys Inc.
  • Ubiquity Genomics Inc.
  • Vela Diagnostics
  • Wafergen Bio-Systems Inc.
  • Warp Drive Bio Llc.
  • Xcell Biosciences Inc.
  • Yikon Genomics Co. Ltd.
  • Zhejiang Dian Diagnostics Co. Ltd.
  • Zixin Pharmaceutical Industrial Co, Ltd.
  • ZS Genetics Inc.
Note: Product cover images may vary from those shown
6 of 6
Note: Product cover images may vary from those shown
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