Integrated Nano-Biomechanics provides an integrated look into the rapidly evolving field of nanobiomechanics. The book demystifies the processes in living organisms at the micro- and nano-scale through mechanics, using theoretical, computational and experimental means. The book develops the concept of integrating different technologies along the hierarchical structure of biological systems and clarifies biomechanical interactions among different levels for the analysis of multi-scale pathophysiological phenomena. With a focus on nano-scale processes and biomedical applications, it is shown how knowledge obtained can be utilized in a range of areas, including diagnosis and treatment of various human diseases and alternative energy production.
This book is based on collaboration of researchers from a unique combination of fields, including biomechanics, computational mechanics, GPU application, electron microscopy, biology of motile micro-organisms, entomological mechanics and clinical medicine. The book will be of great interest to scientists and researchers involved in disciplines, such as micro- and nano-engineering, bionanotechnology, biomedical engineering, micro- and nano-scale fluid-mechanics (such as in MEMS devices), nanomedicine and microbiology, as well as industries such as optical devices, computer simulation, plant based energy sources and clinical diagnosis of the gastric diseases.
- Provides knowledge of integrated biomechanics, focusing on nano-scale, in this rapidly growing research field
- Explains how the different technologies can be integrated and applied in a variety of biomedical application fields, as well as for alternative energy sources
- Uses a collaborative, multidisciplinary approach to provide a comprehensive coverage of nano-biomechanics
Section 2: Biomechanics of microcirculation
Chapter 2.1 Behavior of capsules in flow
Chapter 2.2 Behavior of red blood cells
Chapter 2.3 Adhesion of cells
Chapter 2.4 Formation and destruction of the primary thrombus
Section 3: Biomechanics of digestive systems
Chapter 3.1 Dynamics of swallowing
Chapter 3.2 Mixing in stomach
Chapter 3.3 Transport phenomena of gut flora
Section 4: Biomechanics for pathology and treatment
Chapter 4.1 Development of cerebral aneurysms
Chapter 4.2 Electroporation for cancer treatment
Chapter 4.3 Microbubbles for blood transfusion
Chapter 4.4 Percutaneous absorption of medicine
Section 5: Ciliary motion
Chapter 5.1 Ciliary structure
Chapter 5.2 Motor proteins of cilia
Chapter 5.3 Computational modeling of ciliary motion
Section 6: Swimming microorganisms
Chapter 6.1 Swimming of a solitary cell
Chapter 6.2 Suspension of swimming cells
Chapter 6.3 Bioconvection generated by microalgae
Section 7: Microfluidic devices based on biomechanics
Chapter 7.1 Measurement techniques of cellular flow
Chapter 7.2 Controlling cell-free layer
Chapter 7.3 Separation of motile bacteria
Section 8: Biomimetics
Design of fish fin
Bloodsucking of mosquito
Takami Yamaguchi is an Emeritus Professor at the Graduate School of Biomedical Engineering, Department of Biomedical Engineering, Tohoku University, Japan.
Takuji Ishikawa is Professor at the Graduate School of Engineering, Department of Finemechanics, Tohoku University, Japan.
Yohsuke Imai is an Associate Professor at the School of Engineering, Tohoku University, Japan.