Wound Healing. Stem Cells Repair and Restorations, Basic and Clinical Aspects

  • ID: 4399384
  • Book
  • 296 Pages
  • John Wiley and Sons Ltd
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A comprehensive resource on the recent developments of stem cell use in wound healing

With contributions from experts in the field, Wound Healing offers a thorough review of the most recent findings on the use of stem cells to heal wounds. This important resource covers both the basic and translational aspects of the field. The contributors reveal the great progress that has been made in recent years and explore a wide range of topics from an overview of the stem cell process in wound repair to inflammation and cancer. They offer a better understanding of the identities of skin stem cells as well as the signals that govern their behavior that contributes to the development of improved therapies for scarring and poorly healing wounds.

Comprehensive in scope, this authoritative resource covers a wealth of topics such as: an overview of stem cell regeneration and repair, wound healing and cutaneous wound healing, the role of bone marrow derived stem cells, inflammation in wound repair, role and function of inflammation in wound repair, and much more. This vital resource:

  • Provides a comprehensive overview of stem cell use in wound healing, including both the basic and translational aspects of the field
  • Covers recent developments and emerging subtopics within the field
  • Offers an invaluable resource to clinical and basic researchers who are interested in wound healing, stem cells, and regenerative medicine
  • Contains contributions from leading experts in the field of wound healing and care

Wound Healing offers clinical researchers and academics a much–needed resource written by noted experts in the field that explores the role of stem cells in the repair and restoration of healing wounds.

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List of Contributors

1 Stem Cell Regeneration and Repair Overview viiClement D. Marshall, Alessandra A. Moore, Michael T. Longaker, and H. Peter Lorenz

2 Cadherins as Central Modulators of Wound Repair 15Melissa Crawford and Lina  Dagnino

3 Tight Junctions and Cutaneous Wound Healing 31Thomas Volksdorf and Johanna M. Brandner

4 The Role of Microvesicles in Cutaneous Wound Healing 43Alexandra Laberge and Ve´ronique J. Moulin

5 Wound Healing and MicroenvironmentElgin Tu¨rko¨z Uluer, Hafize Seda Vatansever, and Feyzan O¢©  zdal Kurt 67

6 Wound Healing and the Non–cellular Microenvironment 79Hayley S. Ramshaw, Jasreen Kular, and Michael S. Samuel

7 Contribution of Adipose–Derived Cells to Skin Wound Healing 89Barbara Gawronska–Kozak, Joanna Bukowska, Xiying Wu, Amy Lin Strong,  Trivia Frazier, Bruce A. Bunnell, and Jeffrey M.   Gimble

8 Role of Bone Marrow–Derived Stem Cells in Wound HealingFeyzan Ozdal Kurt, Hafize Seda Vatansever, and Elgin Turkoz Uluer 103

9 Role of Vitamin D and Calcium in Epidermal Wound Repair 113Daniel D. Bikle, Chia–ling Tu, and Yuko   Oda

10 Oral Mucosal Healing 125Luisa A. DiPietro and Megan Schrementi

11 Role of Adipose–Derived Stem Cells in Wound Healing: An Update from Isolation to Transplantation 133Selami Demirci, Ays¸egu¨l Dog¢¨an, and Fikrettin S¸ ahin

12 The Hair Follicle as a Wound Healing Promoter and Its Application in Clinical Practice 149Francisco Jimenez, Mar´©¥a Luisa Mart´©¥nez, Eduardo Escario, and Ander Izeta

13 Impaired Wound Healing in Diabetic Ulcers: Accelerated Healing Through Depletion of Ganglioside 167Duncan Hieu M. Dam, Sophia A. Jelsma, and Amy S. Paller

14 Inflammation in Wound Repair: Role and Function of Inflammation in Wound Repair 177Amanda S. MacLeod and Jeffery T. Kwock

15 Inflammation, Wound Healing, and Fibrosis 195Shibnath Ghatak, Vincent C. Hascall, Ricardo Moreno Rodriguez, Roger R. Markwald, and Suniti Misra

16 The Potential Role of Photobiomodulation and Polysaccharide–Based Biomaterials in Wound Healing Applications 211Heidi Abrahamse, Sathish Sundar Dhilip Kumar, and Nicolette Nadene Houreld

17 Is Understanding Fetal Wound Repair the Holy Grail to Preventing Scarring? 225Olivier A. Branford and Kerstin J. Rolfe

18 Inflammation and Cancer 239Suniti Misra, Vincent C. Hascall, Roger R. Markwald, Paul E. O Brien, and Shibnath Ghatak

Index 275
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Kürsad Türksen is a Senior Scientist in Chronic Disease at the Ottawa Health Research Institute and an Asisstant Professor of Biochemistry at the University of Ottawa in Ottawa, ON, Canada.

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