Clinical Reproductive Science

  • ID: 4454551
  • Book
  • 432 Pages
  • John Wiley and Sons Ltd
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The field of clinical reproductive science continues to evolve; this important resource offers the basics of reproductive biology as well as the most recent advances in clinical embryology. The editor a noted expert in the field focuses on the discipline and covers all aspects of this field. The text explores causes of male and female infertility and includes information on patient consultation and assessment, gamete retrieval and preparation, embryo culture, embryo transfer and cryopreservation.

Comprehensive in scope, the text contains an introduction to the field of clinical reproductive science and a review of assisted reproductive technology. The editor includes information on a wide range of topics such as gonadal development, the regulation of meiotic cell cycle, the biology of sperm and spermatogenesis, in vitro culture, embryo transfer techniques, fundamentals of fertilisation, oocyte activation and much more. This important resource:

  • Offers an accessible guide to the most current research and techniques to the science of clinical reproduction
  • Covers the fundamental elements of reproductive science
  • Includes information on the male and female reproductive basics everything from sexual differentiation to foetal development and parturition
  • Explores the long–term health of children conceived through IVF
  • Contains the newest developments in assisted reproductive technology

Clinical Reproductive Science is a valuable reference written for professionals in academia, research and clinical professionals working in the field of reproductive science, clinical embryology and reproductive medicine.

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List of Contributors xi

About the Editor xv

Preface xvii

Acknowledgements xix

About the Companion Website xxi

Section One Reproductive Science: Fundamentals of Human Reproductive Biology 1

1 Sexual Differentiation, Gonadal Development, and Development of the External Genitalia: A Review of The Regulation of Sexual Differentiation 3Rebecca M. Perrett

2 Male and Female Reproductive Anatomy 35Sara Sulaiman and James Coey

3 Fundamentals of Reproductive Endocrinology 45Derrick Ebot, Haider Hilal, Michael Carroll, and James Coey

4 The Ovaries, Oocytes, and Folliculogenesis 57Jacques Gilloteaux and James Coey

5 The Human Spermatozoa 65Allan Pacey and Katrina Williams

6 The Biology of Fertilization 75Michael Carroll

7 Human Embryo Development: From Zygote Stage to Peri ]Implantation Blastocyst 93Stéphane Berneau and Michael Carroll

8 The Female Reproductive Tract and Early Embryo Development: A Question of Supply and Demand 99Henry J. Leese and Daniel R. Brison

Section Two Clinical Reproductive Science: Causes of Male and Female Infertility 109

9 Disorders of Male Reproductive Endocrinology 111Michael Carroll

10 Disorders of Female Reproductive Endocrinology 125Mahshid Nickkho ]Amiry and Cheryl T. Fitzgerald

11 Oocyte Aneuploidy and the Maternal Age Effect 133Mary Herbert

12 Female Reproductive Pathology: Peritoneal, Uterine, and Fallopian Tube Pathologies 147Kenneth Ma Kin Yue, Rosa Trigas, and Edmond Edi ]Osagie

13 Pathologies of the Male Reproductive Tract 159Aarush Sajjad, Muhammad A. Akhtar, and Yasmin Sajjad

14 The Impact of Infections on Reproduction and Fertility 177Val Edwards Jones

15 Nutrition, Fetal Health, and Pregnancy 189Emma Derbyshire

16 The Embryonic Environment and Developmental Origins of Health 195Tom P. Fleming and Congshan Sun

17 Lifestyle and Environmental Impacts on Fertility 205Ana ]Maria Tomova and Michael Carroll

Section Three Clinical Reproductive Science In Practice: IVF and Assisted Reproductive Technologies 215

18 Assessing the Infertile Couple 217Narmada Katakam, Ruth Arnesen, Caroline Watkins, Bert Stewart, and Luciano G. Nardo

19 Ovarian Stimulation Protocols 231Nikolaos Tsampras and Cheryl T. Fitzgerald

20 Oocyte Retrieval Techniques and Culture of Oocytes 241Dawn Yell

21 Sperm Preparation: Strategy and Methodology 251Stephen Harbottle

22 Diagnostic Semen Analysis: Uncertainty, Clinical Value, and Recent Advances 265Mathew Tomlinson

23 Surgical Sperm Retrieval 279Muhammad A. Akhtar, Elizabeth Hester, Solmaz Gul Sajjad, and Yasmin Sajjad

24 In Vitro Fertilization and Intracytoplasmic Sperm Injection 291Bryan Woodward

25 Morphological Assessment of Embryos in Culture 303J. Diane Critchlow

26 In Vitro Culture of Gametes and Embryos The Culture Medium 317Robbie Kerr

27 Incubators in the Assisted Reproductive Technology Laboratory 333Louise Hyslop

28 Embryo Transfer Techniques and Improving Embryo Implantation Rates 341Rachel Cutting

29 Cryopreservation of Gametes and Embryos 351Tope Adeniyi

30 Preimplantation Genetic Diagnosis and Screening 371Colleen Lynch and Brendan Ball

31 Long ]Term Follow ]Up of Children Conceived Through In Vitro Fertilization 385Omar Abdel ]Mannan and Alastair G. Sutcliffe

Index 393

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Michael Carroll
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