Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome, Second Edition, provides an overview of the current diabetes epidemic, outlines the consequences of this crisis, and lays out strategies to forestall and prevent diabetes, obesity and other intricate issues of metabolic syndrome. Contributing experts provide up-to-date global approaches to the critical consequences of metabolic syndrome and make the book an important reference for those working with the treatment, evaluation or public health planning for the effects of metabolic syndrome and diabetes.
Completely revised with 15 new chapters, the book includes coverage of the roles of gut microbiome in obesity and diabetes, macrovascular and microvascular complications, diabetes, metabolic syndrome and kidney disease, aspects of diabetic cardiomyopathy, diabetes, Alzheimer's and neurodegenerative diseases, roles of SGLT2 inhibitors in the treatment of type 2 diabetes, novel biomarkers in diabetes, roles of Trigonella foenum-graecumseed extract in type 2 diabetes, beneficial effects of chromium (III) and vanadium supplements in diabetes, prevention of type 1 diabetes, novel drugs in the therapeutic intervention of type 2 diabetes, eHealth and mobile apps for self-management, artificial pancreatic transplantation, non-invasive glucose monitoring, and the app for glucose regulation.
- Contains a scientific discussion of the epidemiology and pathophysiology of the relationship between diabetes and metabolic syndrome
- Includes coverage of Pre-diabetes conditions, plus both Type I and Type II Diabetes
- Presents both prevention and treatment options
SECTION 1 EPIDEMIOLOGY AND OVERVIEW 1. Type1 Diabetes Mellitus: An Overview 2. An Overview on Type 2 Diabetes 3. Pathogenesis of Type 2 Diabetes- A Comprehensive Analysis 4. Managing the Broad Spectrum of Type 2 Diabetes 5. Prediabetes: Prevalence, Pathophysiology and Recognition of Enhanced Risk 6. Obesity and Type 2 Diabetes in Youths: New Challenges to Overcome 7. Diabetes Pathophysiology- A Nutritional Perspective 8. Diabetes Mellitus- A Nurse's Perspective 9. Roles of Environmental Pollution and Pesticides in the Metabolic Syndrome and Diabetes: The Epidemiological Evidence 10. Preventing Diabetes with Diet and Exercise
SECTION 2 TYPES OF DIABETES AND ITS CORRELATION WITH OTHER DISEASES 11. Macrovascular and Microvascular complications 12. Diabetes, Metabolic Syndrome and Kidney disease? 13. An Overview on Diabetic Nephropathy 14. Intricate Aspects of Diabetic cardiomyopathy 15. An Overview on Diabetes, Ocular Health and Blindness 16. Diabetes, Alzheimer's and Neurodegenerative Diseases: Type 3 Diabetes 17. Role of Peripheral Neuropathy in the Development of Foot Ulceration and Impaired Wound Healing in Diabetes Mellitus 18. An Overview on Gestational Diabetes
SECTION 3 MOLECULAR INSIGHTS OF DIABETES AND METABOLIC SYNDROME 19. Gene-Environment Interaction in the Pathogenesis of Type 2 Diabetes 20. Roles of SGLT2 inhibitors in the Treatment of Type 2 Diabetes 21. Epigenetics in the Pathophysiology of Type 2 Diabetes 22. Targeting the metabolic syndrome and type 2 diabetes by preventing inflammation 23. Novel Biomarkers in Diabetes SECTION 4 PATHOPHYSIOLOGY 24. Sleep, Hypertension and Diabetes 25. Roles of Pancreatic Cell Functions, Liver, Skeletal Muscle and Adipose Tissues in Diabetes and Metabolic Syndrome
SECTION 5 PREVENTION AND TREATMENT 1: DIET, EXERCISE, SUPPLEMENTS AND ALTERNATIVE MEDICINES 26. Antioxidants, Healthy Diet and Diabetes 27. Oxidative stress and nutrition in Diabetes 28. Molecular Mechanisms of Diabetes Prevention by Structurally Diverse Antioxidants 29. Exercise and Physical Activity in the Prevention of Diabetes and Metabolic Syndrome 30. An Overview on Nutraceuticals and Herbal Supplements for Diabetes and Metabolic Syndrome 31. Therapeutic Effect of Fucoxanthin on Metabolic Syndrome and Type 2 Diabetes 32. Roles of Trigonella foenum-graecum seed extract in Type 2 Diabetes 33. Beneficial Effects of Chromium (III) and Vanadium Supplements in Diabetes 34. Effects of Supplemental Fiber in Type 2 Diabetes Mellitus 35. Meal Plans for Diabetics: Caloric Intake, Calorie Counting and Glycemic Index 36. Ayurveda and Metabolic Diseases
Whole is greater than Sum of Parts
SECTION 6 PREVENTION AND TREATMENT 2: DRUGS AND PHARMACEUTICALS 37. Novel Drugs in the Therapeutic Intervention of Type 2 Diabetes 38. The Evolution of Glucose-Lowering Drugs for Type 2 Diabetes
SECTION 7 NOVEL INNOVATIONS 39. Artificial Pancreatic Transplantation (Artificial Pancreatic Device System)(Pancream Genesis) 40. Non-Invasive Glucose Monitoring 41. App for Glucose Regulation
SECTION 8 DIABETES IN ANIMALS AND TREATMENT 42. Diabetes Mellitus in Animals: Diagnosis and Treatment of Diabetes Mellitus in Dogs and Cats
Debasis Bagchi, PhD, MACN, CNS, MAIChE, received his Ph.D. in Medicinal Chemistry in 1982. He is a Professor in the Department of Pharmacological and Pharmaceutical Sciences at the University of Houston College of Pharmacy, Houston, TX, and Chief Scientific Officer at Cepham Research Center, Piscataway, NJ, Adjunct Faculty in Texas Southern University, Houston, TX. He served as the Senior Vice President of Research & Development of InterHealth Nutraceuticals Inc, Benicia, CA, from 1998 until Feb 2011, and then as Director of Innovation and Clinical Affairs, of Iovate Health Sciences, Oakville, ON, until June 2013. Dr. Bagchi received the Master of American College of Nutrition Award in October 2010. He is the Past Chairman of International Society of Nutraceuticals and Functional Foods (ISNFF), Past President of American College of Nutrition, Clearwater, FL, and Past Chair of the Nutraceuticals and Functional Foods Division of Institute of Food Technologists (IFT), Chicago, IL. He is serving as a Distinguished Advisor on the Japanese Institute for Health Food Standards (JIHFS), Tokyo, Japan. Dr. Bagchi is a Member of the Study Section and Peer Review Committee of the National Institutes of Health (NIH), Bethesda, MD. He has published 321 papers in peer reviewed journals, 30 books, and 18 patents. Dr. Bagchi is also a Member of the Society of Toxicology, Member of the New York Academy of Sciences, Fellow of the Nutrition Research Academy, and Member of the TCE stakeholder Committee of the Wright Patterson Air Force Base, OH. He is also Associate Editor for the Journal of Functional Foods, Journal of the American College of Nutrition, and the Archives of Medical and Biomedical Research, and is also serving as Editorial Board Member of numerous peer reviewed journals, including Antioxidants & Redox Signaling, Cancer Letters, Toxicology Mechanisms and Methods, and The Original Internist, among others.
Dr. Sreejayan Nair is a Professor of Pharmacology and the Associate Dean for Research in the School of Pharmacy, College of Health Sciences, University of Wyoming. He also serves as the Director of the interdisciplinary Biomedical Sciences Graduate Program in the University of Wyoming. Dr. Nair earned his bachelors, masters and PhD degree in Pharmaceutical Sciences from the College of Pharmaceutical Sciences, Manipal, India. He received his post-doctoral trainings at the Department of Medicine-II, Ludwig Maximillians University, Klinikum Grosshadern, Munich, Germany, and at the Department of Physiology, University of Tennessee Health Sciences Center, Memphis, TN. His research interests are diabetes and cardiovascular disease. He has published over 75 research papers in peer-reviewed journals and presented at various national and international conferences. His research has been funded by the American Heart Association, American Diabetes Association, and the National Institutes of Health. He has co-edited three books related to diabetes and cardiovascular disease. He is a Fellow of the American College of Nutrition.