Drug Overview: Trelstar

  • ID: 4462181
  • Drug Pipelines
  • 8 pages
  • Datamonitor Healthcare
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Drug Overview

Trelstar (triptorelin; Allergan) is a gonadotropin-releasing hormone (GnRH) receptor agonist which acts on the pituitary gland to stimulate luteinizing hormone (LH) release, resulting in a temporary surge in serum testosterone levels known as "flare." Persistent use of GnRH agonists over time causes downregulation of GnRH receptors in the pituitary gland, generating a significant reduction in LH and follicle-stimulating hormone secretion. This has the effect of complete shutdown of testosterone production in the testes, resulting in chemical castration.
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Product Profiles
Trelstar: Prostate cancer

List of Figures
Figure 1: Trelstar sales for prostate cancer across the US and five major EU markets, by country, 2017-26

List of Tables
Table 1: Trelstar sales for prostate cancer across the US and five major EU markets, by country ($m), 2017-26
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