Computational Biomechanics is an accessible, comprehensive text for teaching and further reading. It focuses on the use of patient-specific finite element models in tissue biomechanics, providing a collection of papers from subject matter experts, all from biomedical engineering perspectives. Each chapter takes a systematic approach to problem-solving within computational biomechanics using open source software tools. Verification and validation process for models are also covered, with methods presented in case studies that give readers examples to replicate in their own work. Content covered includes multi-physics, multi-scale, and multi-domain approaches, molecular dynamics, continuum and FEA models, cell mechanics, and material models.
- Includes a unique focus on tissue biomechanics
- Uses open source software tools FEBio and OpenSim for computational biomechanical modeling
- Includes multi-physics, multi-scale, and multi-domain approaches, molecular dynamics, continuum and FEA models, cell mechanics, and material models
Part I- General topics 1. Computational biomechanics: multi-physics, multi-scale, and multi-domain approaches 2. Multi-scale computational biomechanics 3. Mixture theory 4. Molecular dynamics models of skeletal tissues 5. Inverse problems in computational biomechanics
Part II- Tissue biomechanics 6. Continuum models of bone biomechanics 7. Finite element models of bone at the micro-scale 8. Computational cartilage biomechanics 9. Computational models of diffusion in cartilage 10. Finite element models of skeletal muscle 11. Computational biomechanics of soft skeletal tissues (tendon, ligament, etc) 12. Biomechanics of intervertebral disc 13. Biomechanics of the implant-tissue complex 14. Computational biomechanics of blast injuries
Part III- From cells to tissues 15. Computational cell mechanics 16. Theoretical models of tissue growth, remodeling, and adaptation 17. Computational tissue engineering
Part IV- Multi-domain computational biomechanics 18. Statistical shape and appearance models of tissues 19. Large-scale musculoskeletal models 20. Patient-specific computational biomechanics models
Part V- Open source software for computational biomechanics 21. FEBio: An open source program for finite element modeling in biomechanics 22. OpenSim: An open source program for musculoskeletal modeling
Dr. Amir A. Zadpoor received the Early Career Researcher Award on the 6th International Conference on Mechanics of Biomaterials and Tissues in Dec 2015. His research interests include additive manufacturing, biofabrication, biomaterials, and tissue biomechanics. He is an editor on Elsevier's journal Mechanical Behavior of Biomedical Materials. He has written over 100 articles, and serves on 13 academic editorial boards.
Dr Hongyan Yuan, PhD is currently Assistant Professor of Mechanical Engineering at University of Rhode Island