Circulating Tumor Cell (CTC) Diagnostics: Technologies and Global Markets

  • ID: 4516194
  • Report
  • Region: Global
  • 302 pages
  • BCC Research
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until Jun 30th 2018
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FEATURED COMPANIES

  • Adnagen
  • Biocep Ltd.
  • Celltrafix Inc.
  • Cynvenio Biosystems Inc.
  • Greiner Bio-One Gmbh
  • Miltenyi Biotec
  • MORE
Report Scope:

The scope of this study is clinical testing, prognostic and monitoring markets for CTCs in cancer. The report also includes the clinical research segment, currently approved CTC tests and their markets. The regulatory environment, current technologies, new technologies, cancer incidence, market projections and market share along with the latest trends and new developments in this area are included to support the clinical testing market.

The research segment of the market includes numerous competitors with different capabilities, developing and commercializing products such as CTC isolation devices and protocols, CTC characterization reagents, assay and instrumentation, and various identification technologies based on cell imaging. These market players include specialized or research-based companies that contribute considerably to the technological advancements in the field of CTC technologies.

The data collected for the report is focused on breast, prostate and colorectal cancers for which clinical data and tests are available currently on the market. CTCs in other cancers are being researched and some are in clinical trials; these are not included within the scope of this report.

Report Includes:
  • 118 Tables
  • An overview of the global market for cancer diagnostics, based on circulating tumor cells, which are used to increase understanding of tumor cell biology and metastatic cancer as a disease.
  • Analyses of global market trends, with data from 2016, estimates from 2017, and projections of compound annual growth rates (CAGRs) through 2022.
  • Discussions covering the advantages and disadvantages of CTC enrichment techniques.
  • Estimations of cancer incidence, cancer deaths, new cases by type in the United States, and breast cancer statistics and facts.
  • Examination of growth opportunities and drivers in the CTC market and recent breakthroughs in research, along with a patent analysis.
  • Information about the clinical testing, prognostic, and monitoring markets for CTCs in cancer.
  • Coverage of approved CTC tests and their markets, and the regulatory environment.
  • Company profiles of major players across various product categories, including Cytotrack, Menarini-Silicon Biosystems And A. Menarini Diagnostics (Veridex Llc), Greiner Bio-One Gmbh, Cynvenio Biosystems Inc., Biofluidica Microtechnologies Llc and Advanced Cell Diagnostics
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FEATURED COMPANIES

  • Adnagen
  • Biocep Ltd.
  • Celltrafix Inc.
  • Cynvenio Biosystems Inc.
  • Greiner Bio-One Gmbh
  • Miltenyi Biotec
  • MORE

1 Introduction

  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Intended Audience
  • Scope of the Study
  • Methodology
  • Information Sources
  • Geographic Breakdown
  • Analyst's Credentials
  • Related Research Reports

2 Summary and Highlights

3 Circulating Tumor Cells

  • Cancer
  • Recent Advances in Technology
  • Invasive Power
  • Circulating Tumor Cells
  • Phenotypic Characteristics
  • CTC Clusters
  • CTC Detection
  • Cancer Stem Cells (CSCs)
  • Circulating Tumor Cells- Potential Uses
  • Proliferative Activity
  • Epithelial Marker Genes on Circulating Tumor Cells
  • Circulating Tumor Cells and Stem Cell-Like Phenotype
  • CTCs and Primary Tumor Cells: Comparison
  • Metastasis
  • Future Directions
  • Metastatic Development in Cancer Patients
  • Circulating Tumor Cell Migration
  • Important Markers of Distant Metastasis
  • Circulating Tumor Cell Detection
  • Methods
  • CellSearch Method
  • Epic Sciences Method
  • Maintrac
  • ISET Test
  • Challenges for Detection
  • Clinical Application of Circulating Tumor DNA
  • Circulating Tumor Cells as Predictor of Response to Therapy
  • Measurement of CTCs-Applications
  • Conclusion

4 Incidence of Cancer

  • Worldwide Growth in the Incidence of Cancer
  • Causes of Cancer
  • Risk Factors for Cancers
  • Burden of Cancer
  • Avoiding Risk Factors
  • Early Detection
  • Treatment
  • Palliative Care
  • World Health Organization Response
  • World Cancer Statistics
  • Cancer and the Global Impact
  • Global Patterns
  • Future of Cancer
  • Common Types of Cancers
  • U.S. Cancer Incidence
  • Global Breast Cancer
  • Colorectal Cancer
  • Prostate Cancer
  • Cancer in Europe
  • Prostate Cancer in Asia
  • Other Nations
  • Conclusions

5 Technologies

  • Finding Circulating Tumor Cells
  • Why CTCs?
  • Current CTC Detection and Isolation Methods
  • New Technologies for Detection
  • Cancer Prognosis
  • CTC Detection Techniques - Requirements
  • Nucleic Acid-based Methods
  • Clinical Testing
  • Summary
  • New Emerging Technologies

6 Circulating Tumor Cells and Cancer Diagnostics

  • Use of CTCs for Diagnosis
  • Current Methods and Applications
  • Circulating Tumor Cells in Prostate Cancer: Case Studies
  • CTCs in Companion Diagnostics
  • Newer Technologies in Development
  • Molecular Analyses of CTC
  • Conclusions

7 CTCs in Clinical Trials

  • CTC Diagnostics
  • Circulating Tumor Cell Technology
  • Potential Therapeutic Uses of Circulating Tumor Cells
  • Challenges in the Detection of Circulating Tumor Cells
  • CTCs as Clinical Biomarkers
  • PCR-based Markers
  • Circulating Tumor Cells in Cancer -Current Status
  • Prognostic and Predictive Value of CTCs
  • CTCs in Clinical Cancer Management
  • Existing Technologies in Clinical Trials
  • Clinical Studies Using CellSearch Technology
  • Approvals
  • Recent Studies
  • Possible Use of CTCs and DTCs as New Biomarkers
  • Clinical Applications
  • Application of CTC Technologies to Clinical Testing
  • CTC Technologies for Clinical Development
  • Standard Recommendations
  • CTC Number as a Prognostic Biomarker
  • Prognostic Studies
  • CTCs as a Surrogate Response Biomarker
  • CTCs as a Real-time Biopsy
  • CTC Chip Technology and EGFR Mutation Analysis
  • CTC Characterization after Enrichment Using the CellSearch Platform
  • Final Remarks

8 Circulating Tumor Cell Market

  • Invasive Cancer
  • Cancer Survival
  • Global Annual Oncology Market
  • Cancer Therapy
  • Aging and Cancer
  • Cancer Drug Pipeline
  • Cancer Costs in the U.S.
  • Japan Oncology Drugs Market
  • Breast Cancer
  • Colon and Rectum
  • Prostate
  • Chemotherapy Market
  • Cancer Testing Market
  • Current Cancer Diagnostic Tests
  • A Universal Tumor Test-Is it Possible?
  • Cancer Biomarker Testing Market
  • Molecular Diagnostics
  • Cancer Biomarker Tests
  • Cancer Disease Management
  • Personalized Cancer Testing
  • Circulating Tumor Cell Market-A New Approach
  • Clinical Diagnostics Market
  • Current Status of the Market
  • Future and Next Steps

9 Patents Overview

  • Key Patents
  • Menarini-Silicon Biosystems/Veridex
  • Magsweeper
  • Scripps Research Institute (EPIC Sciences)
  • CellPoint Diagnostics
  • University of Washington
  • Biofluidica
  • Adnagen
  • Filtini
  • Ikonisys
  • Aviva Biosciences
  • Harvard University-Mehmet Toner, PhD
  • Cellective Dx
  • Johns Hopkins University
  • Medical Discovery Partners
  • Cynvenio Biosystems
  • ScreenCell
  • Canopus Bioscience
  • Advanced Cell Diagnostics
  • Biocept
  • TRUECELLS
  • Roche Molecular Systems and the University of North Carolina
  • Cellectar Biosciences
  • The General Hospital Corp.
  • The Trustees of the University of Pennsylvania Patents
  • Epic Sciences
  • Immunomedics

10 Selected Company Profiles

  • Companies
  • Key Players
  • Key Company Profiles
  • Adnagen
  • Advanced Cell Diagnostics
  • Apocell
  • Aviva Biosciences
  • Biocep Ltd.
  • Biocept Inc.
  • Biofluidica Microtechnologies Llc
  • Canopus Biosciences
  • Cellmax Life
  • Celltrafix Inc.
  • Celula
  • Clearbridge Biomedics
  • Creatv Microtech Inc
  • Cynvenio Biosystems Inc.
  • Cytotrack
  • Epic Biosciences
  • Fluxion Biosciences
  • Greiner Bio-One Gmbh
  • Ikonisys Inc.
  • Ivdiagnostics Inc
  • Janssen Diagnostics
  • Menarini-Silicon Biosystems
  • Miltenyi Biotec
  • Nanostring Technologies Inc.
  • Natural Nano Inc.
  • Rarecells
  • Screencell
  • Stemcell Technologies
  • Synergex Corp.
  • Sysmex Corp.
  • Vitatex Inc.
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  • Adnagen
  • Advanced Cell Diagnostics
  • Apocell
  • Aviva Biosciences
  • Biocep Ltd.
  • Biocept Inc.
  • Biofluidica Microtechnologies Llc
  • Canopus Biosciences
  • Cellmax Life
  • Celltrafix Inc.
  • Celula
  • Clearbridge Biomedics
  • Creatv Microtech Inc
  • Cynvenio Biosystems Inc.
  • Cytotrack
  • Epic Biosciences
  • Fluxion Biosciences
  • Greiner Bio-One Gmbh
  • Ikonisys Inc.
  • Ivdiagnostics Inc
  • Janssen Diagnostics
  • Menarini-Silicon Biosystems
  • Miltenyi Biotec
  • Nanostring Technologies Inc.
  • Natural Nano Inc.
  • Rarecells
  • Screencell
  • Stemcell Technologies
  • Synergex Corp.
  • Sysmex Corp.
  • Vitatex Inc.
Note: Product cover images may vary from those shown
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