Nanosystems with different compositions and biological properties have been extensively investigated for drug delivery and therapeutic applications. This book explores both the classes of nanomaterial, their characterization and biological interactions, and the applications of nanomaterials in drug delivery. By providing a broad range of knowledge regarding synthesis and characterization, readers are enabled to develop a fuller understanding of drug delivery technology.
The chapters of this volume describe the techniques successfully employed for the application of nanocarriers loaded with the antioxidant enzyme, catalase, and targeted to endothelial cells. Methods of nanocarrier synthesis, loading within various systems, and the characterization of nanocarrier for targeting activities are covered in this volume. The advantages and disadvantages and applications of specific designs are explored by the authors. Due to the modular nature of the targeting methodology employed, it is believed that these protocols will provide a solid foundation for the formulation of a wide variety of nanodrug targeting strategies.
Reflecting the interdisciplinary nature of the subject matter, this book includes contributions by experts from different fields, with various backgrounds and expertise. This book will appeal to researchers as well as students from different disciplines such as materials science and technology and various biomedical fields. Coverage includes industrial applications, and bridge the gap between lab-based research and practical industrial applications.
The resulting work is a reference, and practical source of guidance for researchers, students and scientists working in the fields of nanotechnology, materials science and technology and biomedical science.
- The interdisciplinary approach and authorship enables readers from different fields to access recent research and protocols across traditional boundaries
- The focus on protocols and techniques, as well as the knowledge base of the field, will enable those in industry (R&D) to learn about and successfully deploy cutting-edge techniques
- Current and emerging classes of nanomaterials are explored, with their fundamentals and applications made accessible to an inter-disciplinary readership from academic and industrial spheres
2. Application of Peptide in Nano-drug delivery systems
3. Lipid based nanoparticles for drug delivery systems
4. Graphene based Nano-vehicles for drug delivery
5. Applications of Carbon Nanotubes in drug delivery system: A comprehensive review
6. Nano-Lipid Materials for drug delivery systems: A Comprehensive Review
7. Nanostructure Drug Delivery System is an Option to Solve Antimicrobial Drug Resistance: Perspective Review
8. Protein nanocarriers for targeted drug delivery
9. Mechanism for the development of nano-based drug delivery system
10. Microscopy of nanomaterial for drug delivery
11. Nanomaterial for drug delivery: Recent developments on Spectroscopic characterization
12. Design and Characterization of Nano-Particulate Drug Delivery
13. Thermoresponsive drug delivery systems, Characterization, and Application
14. Stimuli-responsive nanomaterial for drug delivery
15. Stability studies on nanomaterials used in the drug
16. Nano-Drugs: Are they safe? Their toxicity and regulatory aspects
17. Nano-Drugs in Market: A global perspective on regulatory issues
18. Nano-Drugs: A critical review on its market and patents
19. Smart polymeric biocatalyst
20. Nano-based carriers for brain drug delivery
21. Administration routes for Nano-Drugs and Characterization of nanodrug loading
Shyam Mohapatra is Distinguished USF Health Professor, Director of the Division of Translational Medicine at the University of South Florida. He also directs the USF Center for Research and Education in Nanobioengineering and is a Research Career Scientist at the James A. Haley VA Hospital in Tampa. He also serves as Associate Dean of Graduate Programs at the USF College of Pharmacy, and established a highly innovative Master of Science program in Pharmaceutical Nanotechnology. He has published over 170 papers and holds over 30 U.S. and international patents. He is a Fellow of the AAAAI, NAI, and AIMBE, and a 2014 inductee of the Florida Inventors Hall of Fame.
Dr. Shivendu Ranjan has extensive expertise in Micro/Nanotechnology and is currently working as Head R&D and Technology Development at E-Spin Nanotech Pvt. Ltd. He has founded and drafted the concept for the first edition of the "VIT Bio Summit in 2012, and the same has been continued till date by the university. He has worked in CSIR-CFTRI, Mysuru, India as well as UP Drugs and Pharmaceutical Co. Ltd., India and IIFPT, Thanjavur, MoFPI, Govt of India. At IIFPT, Thanjavur, he was involved in a project funded by a leading pharmaceutical company, Dr. Reddy's Laboratories and have successfully engineered micro-vehicles for model drug molecules.
His research interests are multidisciplinary and include: Micro/Nanobiotechnology, Nano-toxicology, Environmental Nanotechnology, Nanomedicine, and Nanoemulsions. . He is the associate editor of Environmental Chemistry Letters - a Springer journal of 3.59 impact factor - and an editorial board member in Biotechnology and Biotechnological Equipment(Taylor and Francis). He is serving as executive editor of a journal in iMed Press, USA, and also serving as editorial board member and referee for reputed international peer-reviewed journals. He is the author of many books and edited six books.
Dr. Nandita Dasgupta has vast working experience in Micro/Nanoscience and is currently working at LV Prasad Eye Institute, Bhubaneswar, India. She has exposure of working at university, research institutes and industries including VIT University, Vellore, Tamil Nadu, India; CSIR-Central Food Technological Research Institute, Mysore, India; and Uttar Pradesh Drugs and Pharmaceutical Co. Ltd., Lucknow, India and Indian Institute of Food Processing Technology (IIFPT), Thanjavur, Ministry of Food Processing Industries, Government of India. At IIFPT, Thanjavur, she was involved in a project funded by a leading pharmaceutical company, Dr. Reddy's Laboratories and have successfully engineered micro-vehicles for model drug molecules. Her areas of interest include Micro/Nanomaterial fabrication and its applications in various fields - medicine, food, environment, agriculture biomedical.
She is the author os many books and edited more than 6 books. She has authored many chapters and also published many scientific articles in international peer-reviewed journals. She has received the Certificate for "Outstanding Contribution in Reviewing from Elsevier, Netherlands. She has also been nominated for advisory panel for Elsevier Inc., Netherlands. She is the associate editor of Environmental Chemistry Letters - a Springer journal of 3.59 impact factor - and also serving as editorial board member and referee for reputed international peer-reviewed journals. She has received several awards and recognitions from different national and international organizations.
Mishra, Raghvendra Kumar
Raghvendra Kumar Mishra is currently working as Senior Research Fellow at the International and Interuniversity Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, India. He has received India's most prestigious Visvesvaraya Research Fellowship, and he is currently serving as Visvesvaraya Fellow. He has widely studied the processing of blends, in-situ generation micro and nano fibrillar composites, electromagnetic shielding effect of nanocomposites, decorating and alignment of carbon nanotubes and thermal, dynamic mechanical and structural relationship in polymer blends and nanocomposites .He has bagged several awards from different organizations and technology events. He is serving as reviewer in many international journals e.g. Environmental Chemistry Letters (Springer) etc. He has work as well research experience in Mechanical engineering, Materials science and Technology, and Nanoscience and Nanotechnology. His area of research is multidisciplinary which include Thermodynamics, Heat transfer, Refrigeration and Air-conditioning, Fluid mechanics, Machine design, Solid of Mechanics, Theory of Machine, Power plant engineering, Metal and Ceramic processing, polymers which include Polymer Recycling, Polymer blends, Fibre filled polymer composites, Particulate filled polymer composites and their morphological characterization, Ageing and degradation, Nanomaterials e.g. metallic , metallic oxide, Carbon nanotubes, Graphene, Conducting polymer blends, composites and nanocomposites, Biodegradable polymer blends and composites, Expertise in sophisticated characterization techniques such as Dynamic mechanical analyzer, Differential scanning calorimetry, Thermogravimetric analysis, Spectroscopy, Vector network analyzer, scanning electron Microcopy, Atomic Force Microscopy (AFM), etc.
Professor Thomas is currently Pro-Vice Chancellor of Mahatma Gandhi University and the Founder Director and Professor of the International and Interuniversity Centre for Nanoscience and Nanotechnology. He is also a full professor of Polymer Science and Engineering at the School of Chemical Sciences of Mahatma Gandhi University, Kottayam, Kerala, India.
Prof. Thomas is an outstanding leader with sustained international acclaims for his work in Nanoscience, Polymer Science and Engineering, Polymer Nanocomposites, Elastomers, Polymer Blends, Interpenetrating Polymer Networks, Polymer Membranes, Green Composites and Nanocomposites, Nanomedicine and Green Nanotechnology. Dr. Thomas's ground-breaking inventions in polymer nanocomposites, polymer blends, green bionanotechnological and nano-biomedical sciences, have made transformative differences in the development of new materials for automotive, space, housing and biomedical fields. In collaboration with India's premier tyre company, Apollo Tyres, Professor Thomas's group invented new high performance barrier rubber nanocomposite membranes for inner tubes and inner liners for tyres. Professor Thomas has received a number of national and international awards which include: Fellowship of the Royal Society of Chemistry, London FRSC, Distinguished Professorship from Josef Stefan Institute, Slovenia, MRSI medal, Nano Tech Medal, CRSI medal, Distinguished Faculty Award, Dr. APJ Abdul Kalam Award for Scientific Excellence - 2016, Mahatma Gandhi University- Award for Outstanding Contribution -Nov. 2016, Lifetime Achievement Award of the Malaysian Polymer Group, Indian Nano Biologists award 2017and Sukumar Maithy Award for the best polymer researcher in the country. He is in the list of most productive researchers in India and holds a position of No.5. Recently, because of the outstanding contributions to the field of Nanoscience and Polymer Science and Engineering, Prof. Thomas has been conferred Honoris Causa (DSc) Doctorate by the University of South Brittany, Lorient, France and University of Lorraine, Nancy, France. Very recently, Prof. Thomas has been awarded Senior Fulbright Fellowship to visit 20 Universities in the US and most productive faculty award in the domain Materials Sciences.
Professor Thomas has published over 800 peer reviewed research papers, reviews and book chapters. He has co-edited 80 books published by different publishers. He is the inventor of 6 patents and has delivered over 300 Plenary/Inaugural and Invited lectures in national/international meetings over 30 countries. He has established a state of the art laboratory at Mahatma Gandhi University in the area of Polymer Science and Engineering and Nanoscience and Nanotechnology through external funding from DST, CSIR, TWAS, UGC, DBT, DRDO, AICTE, ISRO, DIT, TWAS, KSCSTE, BRNS, UGC-DAE, Du Pont, USA, General Cables, USA, Surface Treat Czech Republic, MRF Tyres and Apollo Tyres.