Human Liver Models Market by Drug Discovery Platform (Non-alcoholic Fatty Liver Organoids, Liver-on-a-chip, 2D Models, Animal Models, 3D Bioprinting), and Region (North America, Europe, Asia Pacific, Rest of the World) - Global Forecast to 2022

  • ID: 4529873
  • Report
  • Region: Global, America, Asia, Asia Pacific, Europe, North America, United States
  • 39 Pages
  • Markets and Markets
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FEATURED COMPANIES

  • Ascendance Bio
  • CN Bio
  • Cyfuse Biomedical
  • Emulate
  • HµREL
  • Organovo
  • MORE

“The human liver models market is projected to grow at a CAGR of 13.6% during the forecast period”

The global human liver models market is expected to reach USD 2.56 billion by 2022 from USD 1.35 billion in 2017, at a CAGR of 13.6%. Growing focus on developing alternatives for animal testing models, significant increase in research funding and venture capital investments for the development of liver models, growing initiatives to increase awareness about liver organoids, increasing research activities on liver organoids, increasing prevalence of non-alcoholic fatty liver disease, and growing need for the early detection of drug toxicity to minimize financial losses due to late-stage drug failure are expected to drive the growth of the human liver models market. However, issues related to the incorporation of organoids into existing workflows are expected to restrain the growth of this market to a certain extent.

“By type, the liver-on-a-chip segment is expected to grow at the highest rate during the forecast period”

Based on type, the market is segmented into liver organoids, liver-on-a-chip, 2D models, animal models, and 3D bioprinting. The liver-on-a-chip segment is expected to grow at the highest CAGR during the forecast period. This can be attributed to the simplicity of this model and the ability of on-chip hepatic tissues to maintain metabolic activity and phenotype similar to that of the in vivo environment. Moreover, the majority of the key players, research institutes, and government and non-government organizations are raising funds for the development of innovative liver-based models. In addition, key players operating in this market are entering into partnerships and collaborations with pharmaceutical companies to strengthen their market position. This strategy is enabling market players to evaluate the performance of their livers-on-a-chip offerings in drug development and other pharmaceutical research processes. Such funding initiatives from the government and private investors are expected to provide an impetus to market growth.

“The North American human liver models market is expected to grow at the highest CAGR during the forecast period”

North America is expected to witness the highest growth during 2017 to 2022, owing to well-established pharmaceutical and biotechnology industry and increasing government spending. Furthermore, growing initiatives to increase awareness about organoids and growing incidence of NAFLD is expected to boost the market.

Break of primary participants was as mentioned below:

  • By Company Type – Tier 1–50%, Tier 2–30% and Tier 3–20%
  • By Designation – C-level–30%, Director Level–48%, Others–22%
  • By Region – North America–48%, Europe–20%, Asia Pacific–25%, Row–7%

The key players in the global human liver models market are Emulate (US), Ascendance Bio (US), HµREL (US), CN Bio (UK), Organovo (US), and Cyfuse Biomedical (Japan).

Research Coverage:

  • The report analyzes the human liver models market and aims at estimating the market size and future growth potential of this market based on various segments such as type and region. It provides detailed information regarding the major factors influencing the growth of this market and the regulatory analysis impacting market dynamics.
  • Reasons to Buy the Report
  • The report can help established firms as well as new entrants/smaller firms to gauge the pulse of the market, which in turn would help them garner a greater share. Firms purchasing the report could use one or any combination of the below mentioned three strategies.

This report provides insights into the following pointers:

  • Product Development/Innovation: Detailed insights on upcoming technologies, research and development activities, and product launches in the human liver models market
  • Market Development: Comprehensive information about lucrative emerging markets. The report analyzes the markets for various human liver models across regions
  • Market Diversification: Exhaustive information about products, untapped regions, recent developments, and investments in the human liver models market
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FEATURED COMPANIES

  • Ascendance Bio
  • CN Bio
  • Cyfuse Biomedical
  • Emulate
  • HµREL
  • Organovo
  • MORE

1 Market Overview for Human Liver Models
1.1 Introduction
1.2 Market Dynamics
1.2.1 Drivers
1.2.1.1 Growing Focus on Developing Alternatives for Animal Testing Models
1.2.1.2 Significant Increase in Research Funding and Venture Capital Investments for the Development of Liver Organoids
1.2.1.3 Growing Initiatives to Increase Awareness About Liver Organoids
1.2.1.4 Increasing Research Activities on Liver Organoids
1.2.1.5 Increasing Prevalence of Non-Alcoholic Fatty Liver Disease
1.2.1.6 Growing Need for the Early Detection of Drug Toxicity to Minimize Financial Losses Due to Late-Stage Drug Failure
1.2.2 Restraints
1.2.2.1 Issues Related to the Incorporation of Organoids Into Existing Workflows
1.2.3 Opportunities
1.2.3.1 Increasing Focus on Drug Discovery Activities
1.2.3.2 Rising Demand for Liver Transplantation
1.2.3.3 Growing Healthcare Market in the Asia Pacific and Latin America
1.2.4 Challenges
1.2.4.1 Dearth of Skilled Professionals

2 Industry Speaks – In Vitro Liver Models

3 Human Liver Model Market, By Drug Discovery Platform
3.1 Introduction
3.1.1 Liver Organoids
3.1.2 Liver-On-A-Chip
3.1.3 2D Models
3.1.4 Animal Models
3.1.5 3D Bioprinting

4 Geographic Assessment
4.1 Introduction
4.2 North America
4.2.1 US
4.2.2 Canada
4.3 Europe
4.4 Asia Pacific
4.4.1 China
4.4.2 Japan
4.4.3 India
4.4.4 Rest of Asia Pacific
4.5 Rest of the World
4.6 Author Details

List of Tables:
Table 1 Research Projects and Activities
Table 2 Limitations of Existing Cell Model Systems
Table 3 Scientific and Ethical Comparison of Animal Models, Human Embryo Tissues, and Organoid Models
Table 4 Global Human Liver Model Market, By Type, 2015-2022 (USD Million)
Table 5 Liver-On-A-Chip Market, By Region, 2015-2022 (USD Thousand)
Table 6 Animal Models Market, By Region, 2015-2022 (USD Million)
Table 7 3D Bioprinting Market, By Region, 2015-2022 (USD Million)

List of Figures:
Figure 1 Human Liver Models Market: Drivers, Restraints, Opportunities, & Challenges
Figure 2 Number of Registered Clinical Trial Studies (2005–2017)

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FEATURED COMPANIES

  • Ascendance Bio
  • CN Bio
  • Cyfuse Biomedical
  • Emulate
  • HµREL
  • Organovo
  • MORE

The global human liver models market is projected to reach USD 2.56 Billion by 2022 from USD 1.35 Billion in 2017, at a CAGR of 13.6%. The growth of this market is primarily driven by factors such as the growing focus on developing alternatives for animal testing models, significant increase in research funding and venture capital investments for the development of liver models, growing initiatives to increase awareness about liver organoids, increasing research activities on liver organoids, increasing prevalence of non-alcoholic fatty liver disease, and growing need for the early detection of drug toxicity to minimize financial losses due to late-stage drug failure.

The human liver model market is segmented on the basis of type and region. Based on type, the market is segmented into liver organoids, liver-on-a-chip, 2D models, animal models, and 3D bioprinting.

In 2017, the animal models segment accounted for the largest share of the global market. The growth in the biosimilars market is expected to boost the preclinical market as the development of biosimilars and biopharmaceuticals requires an understanding of the mechanism of action, quantification of pharmacological effects, and interpretation of toxicological data. As animal models are indispensable for learning the disease pathogenesis and progression in humans, the rising demand for preclinical services is expected to drive the demand for animal models. However, the liver-on-a-chip segment is expected to grow at the highest CAGR during the forecast period. This can be attributed to the simplicity of this model and the ability of on-chip hepatic tissues to maintain metabolic activity and phenotype similar to that of the in vivo environment.

Geographic segments in this report include North America, Europe, Asia Pacific, and the RoW. Of these, the North American segment accounted for the largest share of the market in 2017. The human liver market for North America is driven by the presence of a well-established life sciences industry, growing awareness about the organoids technology, increasing government funding, growing incidence of NAFLD, and unavailability of livers for transplantation, increasing investments on research, rising focus on tissue culture-based clinical diagnostics, and the availability of skilled professionals.

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  • Emulate
  • Ascendance Bio
  • HµREL
  • CN Bio
  • Organovo
  • Cyfuse Biomedical
Note: Product cover images may vary from those shown
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