Exosome Diagnostics and Therapeutics: Global Markets - Product Image

Exosome Diagnostics and Therapeutics: Global Markets

  • ID: 4538516
  • Report
  • Region: Global
  • 195 Pages
  • BCC Research
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This Report Represents a Current and Important Business Tool to Evaluate New Commercial Opportunities in the Exosome Diagnostic, Therapeutic and Research Tools Markets

FEATURED COMPANIES

  • Codiak Biosciences
  • Evox Therapeutics Ltd.
  • Exosome Diagnostics Inc.
  • Nanosomix Inc.
  • System Biosciences (SBI)
  • MORE

Report Scope:

This report represents a current and important business tool to evaluate new commercial opportunities in the exosome diagnostic, therapeutic and research tools markets. The geographic scope of this study covers the U.S. and companies worldwide. This market is complex and consists of a number of different sectors, each affected differently by scientific and technological development. The report identifies the main positive and negative factors in each sector and forecasts further trends and product and assay development in every category of this industry.

Report Includes:

  • 35 data tables and 35 additional tables
  • An overview of the global markets and related technologies for exosome diagnostics and therapeutics
  • Analyses of global market trends, with data from 2016 to 2017, estimates for 2018, and projections of compound annual growth rates (CAGRs) through 2023
  • Breakdowns of new and existing diagnostic methods
  • Evaluations of current therapeutics and those likely to be utilized in the near future
  • Analyses of the market’s dynamics, specifically growth drivers, restraints, and opportunities
  • Company profiles of major players in the market, including Codiak BioSciences, Evox Therapeutics, Exosome Diagnostics, Inc., HansaBioMed, NonosomiX, Inc. and System Biosciences (SBI)

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FEATURED COMPANIES

  • Codiak Biosciences
  • Evox Therapeutics Ltd.
  • Exosome Diagnostics Inc.
  • Nanosomix Inc.
  • System Biosciences (SBI)
  • MORE

1 Introduction

  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Scope of Report
  • Information Sources and Methodology
  • Intended Audience
  • Analyst's Credentials
  • Related Reports

2 Summary and Highlights

3 Market and Technology Background

  • Exosome Definition and Nomenclature
  • Discovery of Exosomes
  • Exosomes Biogenesis and Processing
  • Exosome Components
  • DNA in Exosomes
  • Proteins in Exosomes
  • RNA in Exosomes
  • Isolation and Detection of Exosomes
  • Isolation Techniques
  • Exosome Detection
  • Bioinformatics Databases for Exosome Research and Product Development
  • ExoCarta
  • Vesiclopedia
  • EVpedia
  • Exosome Function and Physiology

4 Exosome Diagnostics Market

  • Exosomal Proteins as Diagnostic Biomarkers
  • Exosomal Nucleic Acids as Diagnostic Biomarkers
  • Cancer Diagnostics as Market Potential for Exosome-based Diagnostics Product Development
  • Prostate Cancer as Potential for Diagnostics Development in Exosomes Sector
  • Breast Cancer as Potential for Diagnostics Development in Exosome Sector
  • Bladder Cancer as Potential for Diagnostics Development in Exosome Sector
  • Ovarian Cancer as Potential for Diagnostics Development in Exosome Sector
  • Lung Cancer as Potential for Diagnostics Development in the Exosome Sector
  • Liquid Biopsy as Potential for Diagnostics in Exosome Sector
  • Exosomal Proteins and Nucleic Acids as Cancer Biomarkers in Assay Development
  • CNS Disorders and Neurodegeneration Diseases as Market Potential for Exosome Diagnostics Product Development
  • Infectious Diseases as Market Potential for Exosome Diagnostics Product Development
  • Cardiovascular Diseases as Market Potential for Exosome Diagnostics Product Development
  • Prenatal Testing as Market Potential for Exosome Diagnostics Product Development
  • Organ Transplantation as Market Potential for Exosome Diagnostics Product Development
  • Market Participants in Exosome-based Diagnostics Sector
  • Amarantus BioScience
  • Caris Life Sciences
  • Exosome Diagnostics
  • Exosome Sciences/Aethlon Medical
  • Exosomics Siena SPA
  • Nanosomix
  • NX Pharmagen
  • NX Prenatal
  • Orion Pharma
  • Sistemic
  • Ymir Genomics
  • Additional Exosome-based Diagnostics Market Participants
  • Evaluation of Current Diagnostics Sector in Exosome Market

5 Exosome Therapeutic Market

  • Intrinsic Therapeutic Activity of Exosomes
  • Immunological Compatibility
  • Cargo Capabilities
  • Generation of Exosome-mediated Therapeutics
  • Exosome Isolation and Purification from Biofluids or Cell Culture
  • Engineering Exosomes as Therapeutic Delivery Vehicles
  • Targeting Exosomes to Specific Recipient Cells
  • Designing Exosomes as a Synthetic Vector
  • Market Potential for Exosome Therapeutics
  • Market Participants in Exosome-based Therapeutics Sector
  • Aegle Therapeutics
  • Aethlon Medical
  • Anjarium Biosciences
  • BioRegenerative Sciences
  • Capricor Therapeutics
  • Cell Factory
  • Codiak BioSciences
  • Creative Medical Technology Holdings (CMTH)
  • DreiRosen Pharma
  • Evox Therapeutics
  • ExoCoBio
  • ExoCyte Therapeutics
  • Exogenus Therapeutics
  • Exopharm
  • Exotech Bio
  • Exovita Biosciences
  • Intrexon Corp
  • Kimera Labs
  • MDimune
  • MolecuVax
  • Panacea Pharmaceuticals, Inc.
  • Paradigm Pharmaceuticals
  • ReCyte
  • Regeneus
  • ReNeuron
  • Therapeutics Solutions International
  • Unicyte AG
  • Additional Pharma and Biotech Companies with Potential Exosome Research Projects
  • Clinical Trials as Indicator for Exosome Market Development
  • Evaluation of Current Therapeutics Sector in Exosome Market

6 Exosome Reagents and Research Tools Market

  • Market Overview
  • Isolation Methodologies and Reagents for Exosome
  • Detection Methodologies and Reagents for Exosome Research
  • Characterization Methods and Reagents for Exosome Research
  • Engineering Methods and Reagents for Exosome Research
  • Additional Products and Reagents for Exosome Research
  • Market Participants for Reagents and Tools for Exosome Research
  • 101Bio
  • AMSBIO
  • Cell Guidance Systems
  • Ciloa
  • Evomic Science
  • Excytex
  • ExoCan
  • HansaBiomed (Lonza)
  • IZON Science
  • NanoSight (Malvern Instruments)
  • Nanoview Biosciences
  • System Biosciences (SBI)
  • Additional Market Participants for Reagents and Tools for Exosome Research
  • Evaluation of Current Tools and Reagents Sector in the Exosome Market

7 Impact of Exosome Research on Specific Biopharmaceuticals Market

  • Exosome Research Impact on Biomarker and Diagnostics Industry
  • Exosome Research Impact on MicroRNA Market
  • Exosome Research Impact on the Liquid Biopsy Market
  • Exosome Research Impact on Stem Cell Technologies Market
  • Exosome Research Impact on Prenatal Diagnostic Market
  • Exosome Research Impact on Agriculture and Food Industry
  • Exosome Research, Microfluidics and Nanotechnology
  • Exosome Research Impact on Skincare Industry

8 Patent Review/ New Developments

9 Market Summary

10 Company Profiles

  • Codiak Biosciences
  • Evox Therapeutics Ltd.
  • Exosome Diagnostics Inc.
  • Hansabiomed Life Sciences Ltd. (Lonza)
  • Nanosomix Inc.
  • System Biosciences (SBI)

List of Tables
Summary Table: Global Market for the Exosome Industry, by Application Sector, Through 2023
Table 1: Nomenclature of Exosome Particles
Table 2: Publication Trend on the Subject of Exosome, 2003-2017
Table 3: Steps in Exosome Biogenesis and Processing
Table 4: Proteins Essential in Exosome Biogenesis and Processing
Table 5: Proteins Found in Exosomes
Table 6: MicroRNA in Different Bodily Fluids
Table 7: Methods for Exosome Isolation
Table 8: Distribution of Exosomes Isolation Procedures in the Studies Cataloged in ExoCarta
Table 9: Statistics of Data Cataloged in ExoCarta, 2012 and 2017
Table 10: Statistics of Data Cataloged in Vesiclepedia, 2012 and 2017
Table 11: Statistics of Data Cataloged in EVpedia, 2014
Table 12: Comparison of Databases for Exosome Studies
Table 13: Examples of Exosomal Proteins for Clinical Diagnostic Applications
Table 14: Examples of Exosomal MicroRNA for Clinical Diagnostic Applications
Table 15: Statistics for Prostate Cancer, 2017
Table 16: Global Market for Prostate Cancer Diagnostics and Related Cost
Table 17: Statistics for Breast Cancer, 2017
Table 18: Global Market for Breast Cancer Diagnostics, Through 2019
Table 19: Statistics for Bladder Cancer, 2017
Table 20: Global Market for Bladder Cancer Diagnostics, 2017
Table 21: Statistics for Ovarian Cancer, 2017
Table 22: Global Market for Ovarian Cancer Diagnostics, 2017
Table 23: Statistics for Lung Cancer, 2017
Table 24: Global Market for Lung Cancer Diagnostics, 2017
Table 25: Liquid vs. Tissue Biopsy
Table 26: Global Market for Liquid Biopsy Including Research Tools, Services and Diagnostics, Through 2022
Table 27: Exosomal Protein Biomarkers from Body Fluids of Patients in Pre-clinical and Clinical Studies
Table 28: Exosomal Nucleic Acid Biomarkers in Pre-clinical and Clinical Studies
Table 29: U.S. Statistics Data for Alzheimer’s, 2017
Table 30: Global Market for Alzheimer’s Disease Therapeutics and Diagnostics, Through 2020
Table 31: Global Statistics Data for Hepatitis C Infection, 2015
Table 32: Global Market Value for Hepatitis C Diagnostics, 2017
Table 33: U.S. Statistics Data for Cardiovascular Diseases, 2017
Table 34: Global Market for Cardiovascular Diagnostics, 2017
Table 35: Global Market for Prenatal Diagnostics, Predictive Tests and Neonatal Monitoring, Through 2019
Table 36: Global Market for Organ and Tissue Transplantation Products and Devices, Through 2020
Table 37: Comparison of Exosome-based Diagnostics Approach to Other Liquid Biopsy Platforms
Table 38: Main Market Participants in Exosome-based Diagnostics Sector
Table 39: Global Market for Exosome Diagnostics, Through 2023
Table 40: Examples of Physiological Effect of Exosome Delivery
Table 41: Top Five Vaccine Providers, 2016
Table 42: U.S. Statistics for Burn Injuries
Table 43: U.S. Statistics for Pressure Ulcer
Table 44: Revenues for Aethlon Medical, 2012-2016
Table 45: Revenue, Cost and Profits for Capricor Therapeutics, 2012-2016
Table 46: Main Market Participants in Exosome-based Therapeutics Sector
Table 47: Examples of Clinical Trials Related to Exosome Research
Table 48: Examples of Financing for Exosome-based Therapeutics Companies
Table 49: Global Market for Exosome Therapeutics, Through 2023
Table 50: Main Steps in Exosome Research Approach
Table 51: Examples of Commercial Kits and Reagents for Exosome Isolation
Table 52: Percentage of Use Each of Isolation Technique for Exosome Purification
Table 53: Examples of Detection Assay
Table 54: Examples of Antibody Providers for Exosome Research
Table 55: Examples of RNA Extraction Commercial Kits
Table 56: Percentage of Use of Characterization Techniques for Exosome Sample
Table 57: Examples of Purified Exosomes Commercial Products
Table 58: Main Market Participants in Exosome Research Tools and Reagents
Table 59: Global Market for Exosome Research Tools and Reagents Market, Through 2023
Table 60: Examples of Protein Markers in Exosomes and Their Related Pathology
Table 61: Examples of MicroRNA Markers in Exosomes and Their Related Pathology
Table 62: Liquid vs. Tissue Biopsy
Table 63: Global Market for Prenatal Diagnostics, Predictive Tests and Neonatal Monitoring, Through 2019
Table 64: Number of Patents on Exosome Research Filed in Specific Years, 2000-2017
Table 65: Examples of Patents Filed on Exosome Research
Table 66: Search Analysis for Patents Using Specific Keywords
Table 67: Number of Patents and Patent Applications by Some Exosome Market Participants
Table 68: Global Market for Exosome Industry, by Application Sector, Through 2023
Table 69: Examples of Main Market Participants in Exosome Market

List of Figures
Summary Figure: Global Market for the Exosome Industry, by Sector, 2016-2023
Figure 1: Publication Trend on the Subject of Exosome, 2003-2017
Figure 2: Differential Centrifugation Process
Figure 3: Ciliated Porous Device Designed to Isolate Exosomes by Filtration
Figure 4: Sieving Models for Exosome Filtration
Figure 5: Global Market for Exosome Diagnostics, 2016-2023
Figure 6: Global Market for Exosome Therapeutics, 2016-2023
Figure 7: Global Market for Exosome Research Tools and Reagents Market, 2016-2023
Figure 8: Number of Patents Filed in Specific Years on Exosome Research, 2000-2017
Figure 9: Search Analysis for Patents Using Specific Keywords
Figure 10: Global Market for Exosome Industry, by Application Sector, 2016-2023

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FEATURED COMPANIES

  • Codiak Biosciences
  • Evox Therapeutics Ltd.
  • Exosome Diagnostics Inc.
  • Nanosomix Inc.
  • System Biosciences (SBI)
  • MORE

Summary:

Initially, exosome particles were considered “garbage” molecules secreted by cells. Today, many researchers are convinced that these tiny vesicles have unlimited potential in diagnostics and therapeutics, especially in oncology treatments.

By definition, exosomes are small membrane sacs/vesicles, approximately 30 to 100 nanometers (nm) in diameter, that are released by both healthy and cancerous cells. Substances from cell cytoplasm, such as genomic DNA, various RNA species, proteins and lipids are encapsulated into exosomes and shed into the extracellular environment.

Research shows that all fluids in the human body contain exosomes which can transfer cytoplasmic ingredients to other cells either locally or at distant sites. Once reaching the recipient cells, cytoplasmic ingredients can alter their biology.

Scientists believe that various biomolecules in exosomes can be profiled and, consequently, may serve as useful biomarkers for different diseases. Nucleic acids such as RNA or DNA can be isolated from exosomes and further analyzed by various techniques.

Overall, the market for the exosome approach can be divided into three main categories: diagnostics, therapeutics, and research tools.

This report evaluates the diagnostics market affected by exosome research and further potential of exosome-based tests and assays. Indeed, an exosomes approach represents the opportunity to expand and develop the liquid biopsy market, a growing sector in cancer diagnostics.

This report also highlights developments in therapeutics and drug development sectors. There is a significant potential for using exosome depletion as a way of treating disease; cancer-generated exosomes can inhibit the immune response and stimulate angiogenesis, the development of new blood vessels. Consequently, if these exosomes are removed, tumor growth might be inhibited, and anticancer agents can work more efficiently.

In addition, there is a potential for exosomes to be used as targeted delivery vehicles of therapeutic molecules to cancer cells; for example, delivering small interfering RNA-specific molecules (siRNA) for a particular oncogene expressed in a tumor cell.

Life science tool companies develop unique research tools for exosome detection and isolation. Current products offered in this area of industry are discussed in this report.

Although many scientific questions still need to be answered, exosomes serve as a novel and unique platform in the diagnostics and therapeutic sectors. Altogether, exosomes offer a new alternative to current diagnostics and drug development technologies.

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  • Codiak Biosciences
  • Evox Therapeutics Ltd.
  • Exosome Diagnostics Inc.
  • Hansabiomed Life Sciences Ltd. (Lonza)
  • Nanosomix Inc.
  • System Biosciences (SBI)
Note: Product cover images may vary from those shown
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