Pouchitis and Ileal Pouch Disorders: A Multidisciplinary Approach for Diagnosis and Management provides much needed information on the evolution of pouch surgery, pouch surgery techniques, and surgery-associated complications, including inflammatory, functional, neoplastic, and metabolic complications. The book provides information on the anatomy of the pouch, pathogenesis of pouchitis and other pouch disorders, proper diagnostic modalities, and medical, endoscopic and surgical options for those disorders. The information has been compiled from a panel of national and international leading experts in the field, including basic scientists, gastrointestinal (GI) pathologists, GI radiologists, gastroenterologists, and more.
- Features never-before-published information and technology from the vast experience of the contributors and editors in diagnosis and medical, endoscopic, and surgical management of pouchitis and other pouch disorders
- Contains easy to access recommendations from experts
- Provides access to an accompanying website with videos of endoscopic demonstrations of various configurations of the pouch, endoscopic evaluation of pouch disorders, and endoscopic treatment of pouch strictures, fistula, and anastomotic leaks/sinuses
1. General medical therapy for ulcerative colitis 2. Indications and perioperative management for restorative proctocolectomy with the ileal pouch 3. Techniques of colectomy and ileal pouch surgery 4. Factors associated with short- and long-term post-operative complications 5. Stoma, mucus fistula, Hartmann pouch, ileorectal anastomosis, and diverted pouch 6. Ileal pouch for familial adenomatous polyposis 7. Ileal pouch pediatric patients 8. Classification of ileal pouch disorders 9. Genetic factors in the pathogenesis of chronic inflammatory disorders of the pouch 10. Microbiota in pouchitis and de novo Crohn's disease of the pouch 11. Pathogenesis of pouchitis 12. Risk factors for chronic pouch disorders and pouch failure 13. Adverse metabolic diseases after pouch surgery 14. Diagnosis of pouch disorder: Clinical Evaluation 15. Diagnosis of pouch disorders: Endoscopy 16. Diagnosis of pouch disorders: Histology 17. Disease Index Instruments of Pouchitis, Crohn's disease of the Pouch and Cuffitis 18. Diagnosis of pouch disorders: Abdominal and pelvic imaging 19. Diagnosis of pouch disorders: Laboratory tests 20. IBD serology in pouch disorders 21. Diagnosis of Crohn's disease of the pouch 22. Manometry in ileal pouch 23. Extra-intestinal manifestations and concurrent immune-mediated disorders in pouch patients 24. Pouch neoplasia and its surveillance and management 25. Diagnosis and management of cuffitis 26. Diagnosis and management of pouch vaginal fistula 27. Maintenance of a healthy pouch 28. Quality of life in patients with healthy or diseased pouch 29. Medical therapy for pouchitis 30. Medical therapy for Crohn's disease of the pouch 31. Diagnosis and Management of floppy pouch complex 32. Medical Endoscopic, surgical therapy for ileal pouch strictures 33. Endoscopic therapy for acute and chronic anastomotic leak 34. Endoscopic therapy for fistula and abscess 35. Endoscopic therapy for bleeding, bezoar, and anastomotic abdnormalities 36. Surgical treatment for Crohn's disease of the pouch 37. Salvage and revision surgery for failed pouch 37. Special issues: Kock pouch, Barnett Continent Intestinal Reservoir, Diverted pouch 39. Liver surgery in UC patients before and after restorative proctocolectomy 40. Functional pouch disorders 41. Male issues in ileal pouch 42. Female issues in ileal pouch
Prof. Shen is the Ed and Joey Story Endowed Chair, Professor of Medicine of Lerner College of Medicine of Case Western Reserve University, Section Head of IBD and Director of IBD Fellowship at Department of Gastroenterology/Hepatology/Nutrition, the Cleveland Clinic Foundation, Cleveland, Ohio. Prof. Shen is specialized in medical and endoscopic management of inflammatory bowel disease (IBD), colorectal surgery-associated complications, and ileal pouch disorders. He established the subspecialty Pouchitis Clinic in 2002 and the Interventional IBD (i-IBD) Unit in 2009 at Cleveland Clinic, the first and the largest of its kind in the world. Prof. Shen has conducted numerous clinical and translational research projects in IBD, endoscopy, and pouch disorders. Dr. Shen's research has been funded by the National Institutes of Health (NIH), the American College of Gastroenterology (ACG), Broad Foundation, Crohn's and Colitis Foundation (CCF), American Society of Colorectal Surgeons, American Gastroenterological Association (AGA), Broad Foundation, and philanthropy. He lectures extensively in the US and overseas. He has published more than 430 peer-reviewed articles in high-impact journals, including Science, Nat Immunol, PNAS, Nat Rev Gastroenterol Hepatol, Gastroenterology, Gut, Am J Gastroenterol, and Ann Surg. He is a contributor for UpToDate®. He edited or co-edited 4 textbook/reference books in IBD, pouch disorders and interventional IBD. He has been visiting professor/guest professor in more than 60 leading academic institutions in the US and abroad. He is also a grant reviewer for the NIH and professional societies. Prof. Shen serves in editorial boards in a dozen of professional journals and has also served in advisory board for the Food and Drug Administration (FDA). Prof. Shen holds Fellowships in ACG, AGA, and ASGE (American Society for Gastrointestinal Endoscopy). Prof. Shen has won multiple institutional and national awards. He has been the research mentor for more than 100 medical students, medical and surgical residents/fellows, junior faculty, and oversea scholars.