Digital Polymerase Chain Reaction (PCR) Technology: Global Markets

  • ID: 4541503
  • Report
  • Region: Global
  • 77 Pages
  • BCC Research
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This Report Contains Analyses of Global Market Trends, with Data from 2016, and Estimates for 2017, and Projections of CAGRs Through 2022

FEATURED COMPANIES

  • Abbott Laboratories
  • Biological Dynamics Inc.
  • Caredx Inc.
  • Exact Sciences Corp.
  • Integen X, Inc.
  • Nugen Technologies Inc.
  • MORE

Report Scope:

While this report will discuss applicable complementary technologies, it will not go into the market specifics of these complementary technologies. Of particular note are the majority of reagents used for PCR, as there is significant overlap between the reagents used for digital PCR and those used for real-time PCR. This report will focus on the equipment used for digital PCR, reagents specific to the technology, and any particular applications. There will be significant discussion of the end users, including academia, industry, clinical laboratories, and other users.

Report Includes:

  • 14 data tables and 7 additional tables
  • An overview of the global market for digital polymerase chain reaction (PCR) technology
  • Analyses of global market trends, with data from 2016, and estimates for 2017, and projections of compound annual growth rates (CAGRs) through 2022
  • Discussion of key manufacturers, suppliers, users, and a variety of factors influencing demand
  • Relevant Patent analyses
  • Comprehensive company profiles of major players in the market, including Abbott Laboratories, Celula Inc., Fluidigm Corp., IntegenX Inc. and Stilla Technologies

Membership Price:

Contact us for membership pricing.

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FEATURED COMPANIES

  • Abbott Laboratories
  • Biological Dynamics Inc.
  • Caredx Inc.
  • Exact Sciences Corp.
  • Integen X, Inc.
  • Nugen Technologies Inc.
  • MORE

1 Introduction

  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Scope of Report
  • Information Sources
  • Methodology
  • Regional Breakdown
  • Analyst's Credentials
  • Related Reports

2 Summary and Highlights

  • Industry Trends
  • The Marriage of Digital PCR and DNA Sequencing
  • Expansion into Food and Agriculture
  • A Molecular Counting Device
  • Another Weapon in the Cancer Fight
  • Intellectual Property Land Rush

3 Overview of Digital PCR Technology

  • History of the Technology
  • How the Technology Works
  • Variations on the Technology
  • Uses
  • Oncology
  • HIV
  • Next-generation Sequencing
  • Infectious Disease
  • Noninvasive Diagnostics
  • Small Nucleotide Polymorphism Detection
  • Single-cell PCR
  • Summary
  • Sectors
  • Pharmaceutical/Biotech and Clinical Development
  • Clinical Diagnostics
  • Academia
  • Forensics
  • Food and Agriculture
  • Environmental Science
  • Industry Structure
  • Equipment Manufacturers
  • Consumable Manufacturers

4 Market Breakdown by Technology Type

  • Consumables and Reagents
  • Equipment
  • Company Prospects
  • Bio-Rad
  • Fluidigm
  • Life Technologies
  • Stilla Technologies

5 Patent Review/New Developments

  • Key Patents
  • Sandwich Assays in Droplets; Digital Analyte Analysis; and Methods and Compositions for Nucleic Acid Analysis
  • Methods and Devices for Digital PCR
  • Important Patent Applications
  • Digital PCR Systems and Methods Using Digital Microfluidics
  • Quantitating High Titer Samples by Digital PCR
  • Maternal Plasma Transcriptome Analysis by Massively Parallel RNA Sequencing
  • Unitary Biochip Providing Sample-in to Results-out Processing and Methods of Manufacture
  • Single Cell Bar-Coding for Antibody Discovery
  • Methods for Personalizing Cancer Treatment
  • Internal Amplification Control
  • Compositions for Quantitative and/or Semiquantitative Mutation Detection Methods
  • New Patents
  • Research and Development
  • Academia
  • Detection of Human Papillomavirus in Sentinel Lymph Nodes Using Digital PCR
  • Detection of GMO Organisms
  • A Rapid, Accurate and Cost-Effective Method for Identification of Biomarker FcyRIIIa-F158V Genotypes
  • Digital PCR to Time Yeast Cell Development
  • Use of Droplet Digital PCR for Estimation of Fish Abundance and Biomass in Environmental DNA Surveys
  • Digital PCR for the Quantification of Fecal Bacteria in the Water Supply

6 Regulatory Analysis

  • Clinical Diagnostics
  • Laboratory-developed Tests
  • U.S. Food and Drug Administration
  • Centers for Medicare and Medicaid Services
  • Health Canada
  • Stance on LDTs for Europe, Australia and China
  • European Medicines Agency
  • Therapeutic Goods Administration (Australia)
  • China Food and Drug Administration
  • Japan Pharmaceutical and Medical Device Agency
  • Pharmaceutical Development
  • Food and Agriculture Regulation
  • Environmental Regulation
  • Forensic Regulation

7 Company Profiles

  • Abbott Laboratories
  • Adaptive Biotechnologies Corp.
  • Ande Corp
  • Ambergen
  • Biological Dynamics Inc.
  • Bio-Rad Laboratories Inc.
  • Boreal Genomics Corp.
  • Caredx Inc.
  • Caris Life Sciences, Inc.
  • Celula Inc.
  • Exact Sciences Corp.
  • Fluidigm Corp.
  • Genetic Technologies Ltd.
  • Integen X, Inc.
  • Laboratory Corp. Of America (Labcorp)
  • Luminex Corp.
  • Natera Inc.
  • Nugen Technologies Inc.
  • Pacific Biosciences Of California Inc.
  • Population Bio Inc
  • Rarecells Sas
  • Roche Diagnostics Operations, Inc.
  • Stilla Technologies
  • Sysmex Inostics
  • Thermo Fisher Scientific
  • Tocagen, Inc.
  • Viomics, Inc.

List of Tables
Summary Table: Global Market for Digital PCR, by Type, Through 2022
Table 1: Overview of Digital PCR Technology
Table 2: List of Consumables Used in Digital Polymerase Chain Reaction (PCR) Technology
Table 3: Global Market for Digital PCR Industry for Consumables, by End User Industry
Table 4: Global Market for Digital PCR Industry Consumables for Pharmaceutical Research and Development, Through 2022
Table 5: Global Market for Digital PCR Industry Consumables for Noninfectious Disease Clinical Diagnostics, Through 2022
Table 6: Global Market for Digital PCR Industry Consumables for Academia, Through 2022
Table 7: Global Market for Digital PCR for Infectious Disease, Through 2022
Table 8: Global Market for Digital PCR for Next-generation Sequencing, Through 2022
Table 9: Global Market for Digital PCR for Other Molecular Biology Uses, Through 2022
Table 10: List of Equipment Used in Digital PCR Technology
Table 11: Global Market for Digital PCR Equipment for Pharmaceutical Research and Development, Through 2022
Table 12: Global Market for Digital PCR Equipment for Pharmaceutical Research and Development, Through 2022
Table 13: Global Market for Digital PCR Equipment for Noninfectious Disease Clinical Diagnostics, Through 2022
Table 14: Global Market for Digital PCR Equipment for Academia, Through 2022
Table 15: Global Market for Digital PCR Equipment for Infectious Disease, Through 2022
Table 16: Global Market for Digital PCR Equipment for Next-generation Sequencing, Through 2022
Table 17: Global Market for Digital PCR Equipment for Other Molecular Biology Uses, Through 2022
Table 18: Key Patents Issued in the Digital PCR Technology Industry, May 2016-April 2017
Table 19: Key Patent Applications in the Digital PCR Technology Industry, August 2014-January 2017
Table 20: New Patents in the Digital PCR Technology Industry, April 2014-April 2017

List of Figures
Summary Figure: Global Market for Digital PCR, by Type, 2016-2022

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FEATURED COMPANIES

  • Abbott Laboratories
  • Biological Dynamics Inc.
  • Caredx Inc.
  • Exact Sciences Corp.
  • Integen X, Inc.
  • Nugen Technologies Inc.
  • MORE

Novel uses for digital PCR are driving increased adoption of the technology, particularly in sectors such as agriculture, food, and environmental science. Integration of digital PCR in next-generation sequencing (NGS) workflows as a means of detecting the quality of samples have also encouraged the spread of digital PCR. While equipment purchasing growth has slowed somewhat, particularly in early adopting sectors such as pharmaceutical R&D and infectious disease, use of digital PCR equipment will grow as new uses for the technology emerge.

Digital PCR growth is particularly driven by development in the clinical diagnostic space. As there is more experience with the technology in this space, digital PCR has found a niche here among other PCR technologies. Growth in this sector has also been driven by the development of new assay and sample preparation technologies to complement digital PCR. This growth and refinement of the technology will drive the use of digital PCR consumables in all sectors of the life sciences and will support industrial growth for at least the next five years.

Reasons for Doing This Study:

Digital PCR is a novel application of the now 30-year-old PCR technology. The concept involves partitioning a sample of DNA into small, microscopic droplets so that a given sample has either zero or one copy of target DNA, much in the way a microchip has switches that give signals of 0 or 1 within a microchip. Once the sample is partitioned, a PCR reaction takes place in each droplet, which is then detected by technologies similar to those used in quantitative PCR today. These results are interpreted with the use of Poisson statistics to determine the exact copy number of target DNA within a sample. This methodology has the ability to quantify small copy numbers of DNA within a sample, and it can have a wide variety of applications complementary to existing PCR technology, as well as allowing new uses of PCR that would not be feasible with other technologies-particularly as a complement to next-generation sequencing. There are three different variations of digital PCR being marketed, and they all have their strengths and weaknesses.

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  • Abbott Laboratories
  • Adaptive Biotechnologies Corp.
  • Ambergen
  • Ande Corp
  • Bio-Rad Laboratories Inc.
  • Biological Dynamics Inc.
  • Boreal Genomics Corp.
  • Caredx Inc.
  • Caris Life Sciences, Inc.
  • Celula Inc.
  • Exact Sciences Corp.
  • Fluidigm Corp.
  • Genetic Technologies Ltd.
  • Integen X, Inc.
  • Laboratory Corp. Of America (Labcorp)
  • Luminex Corp.
  • Natera Inc.
  • Nugen Technologies Inc.
  • Pacific Biosciences Of California Inc.
  • Population Bio Inc
  • Rarecells Sas
  • Roche Diagnostics Operations, Inc.
  • Stilla Technologies
  • Sysmex Inostics
  • Thermo Fisher Scientific
  • Tocagen, Inc.
  • Viomics, Inc.
Note: Product cover images may vary from those shown
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Note: Product cover images may vary from those shown
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