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Digital Polymerase Chain Reaction (PCR) Technology: Global Markets

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    Report

  • 154 Pages
  • October 2023
  • Region: Global
  • BCC Research
  • ID: 4541503

This research study analyzes the dPCR market, offers revenue forecasts, assesses future trends, and provides strategic recommendations for the success of market participants. The scope of the study is global. This report estimates market data for 2022 (the base year) and forecasts for 2023 through 2028. Figures for 2023 are estimated, except where actual results have been reported. This report includes forecasts by product type, technology, end-use and region from 2023 through 2028. The report also analyzes leading and emerging competitors in the current worldwide dPCR market.

Report Includes

  • 26 data tables and 37 additional tables
  • An overview and analysis of the global market for digital polymerase chain reaction (dPCR) technology
  • Analyses of the global market trends, with historical market revenue data (sales figures) from 2020 to 2022, estimates for 2023, forecasts for 2024, and projections of compound annual growth rates (CAGRs) through 2028
  • Estimates of the market size and revenue forecast for global dPCR market, and corresponding analysis of market shares by product type, technology, end-use and region
  • In-depth information (facts and figures) pertaining to the major factors influencing the market, including drivers, restraints, opportunities and challenges
  • A value chain analysis providing a systematic study of the key intermediaries, with emphasis on manufacturers, suppliers and major end users
  • Discussion of the importance of ESG in the dPCR technology market, including consumer attitudes, an assessment of risks and opportunities, and the ESG practices followed by manufacturers and service providers
  • Analysis of the U.S. patents on digital PCR, and emerging trends and technologies in the industry
  • A look at the major vendors in the global market for dPCR, and an analysis of the industry structure, including market shares and recent M&A activity
  • Identification of the major stakeholders and analysis of the competitive landscape based on recent developments, key financials and revenues by segment
  • Company profiles of the leading market players

Table of Contents

Chapter 1 Introduction
  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Scope of Report
  • What's New in This Update?
  • Methodology and Information Sources
  • Geographic Breakdown
Chapter 2 Summary and Highlights
  • Market Outlook
  • Highlights of the Global dPCR Market
Chapter 3 Market Overview
  • Polymerase Chain Reaction (PCR)
  • Real-Time PCR or Quantitative PCR (qPCR)
  • Digital PCR
  • How the Technology Works
  • Variations on the Technology
  • Uses
  • Oncology
  • Next-generation Sequencing
  • Infectious Disease
  • Noninvasive Diagnostics
  • Small Nucleotide Polymorphism Detection
  • Single-cell PCR
Chapter 4 Market Dynamics
  • Overview
  • Market Drivers
  • Technology Advancements
  • Growing Demand in Clinical Diagnostics
  • Burgeoning Biopharmaceutical Market
  • Growth in Genomic and Biomarker Research
  • Trend toward Personalized Medicine
  • Robust Funding Environment for Biomedical Research
  • Market Challenges
  • High Investment Cost
  • Complexity and Expertise Requirements
  • Technical Limitations and Competition from Alternative Technologies
  • Stringent Regulatory Landscape
  • Key Factors and Impact on Market
Chapter 5 Market Breakdown by Technology
  • Market Overview
  • Droplet-based Digital PCR (ddPCR)
  • Beads, Emulsion, Amplification, Magnetics (BEAMing) dPCR
  • Microfluidics-based dPCR
  • Droplet-based vs. Microfluidics-based dPCR
  • Market Revenue, by Technology
  • Droplet-based dPCR (ddPCR)
  • Microfluidics-based dPCR
Chapter 6 Market Breakdown by Product Type
  • Market Overview
  • Global Market for dPCR, by Product Type
  • Equipment
  • Market Overview
  • Market Revenue
  • Reagents, Consumables and Accessories
  • Market Overview
  • Market Revenue
Chapter 7 Market Breakdown by End Use
  • Market Overview
  • Basic Research
  • Clinical Research
  • Clinical Diagnostics
  • Applied Markets
  • Food and Agriculture
  • Environmental Science
  • Forensics
  • Market Revenue, by End Use
  • Basic Research
  • Market Overview
  • Market Revenue, by Product Type
  • Clinical Research
  • Market Overview
  • Market Revenue, by Product Type
  • Clinical Diagnostics
  • Market Overview
  • Market Revenue, by Product Type
  • Applied Markets
  • Market Overview
  • Market Revenue, by Product Type
Chapter 8 Market Breakdown by Region
  • Market Overview
  • Market Revenue
  • North America
  • Market Revenue, by Product Type
  • Europe
  • Market Revenue, by Product Type
  • Asia-Pacific
  • Market Revenue, by Product Type
  • Rest of the World (RoW)
  • Market Revenue, by Product Type
Chapter 9 ESG Development
  • Introduction to ESG
  • Sustainability in dPCR Industry: An ESG Perspective
  • Key Environmental Issues
  • Consumer Attitudes Toward ESG
  • Industry ESG Performance Analysis
  • Concluding Remarks
Chapter 10 Emerging Technologies and Developments
  • Overview
  • Integrated Microfluidic dPCR
  • Growth Acceleration in CGT Development and Production
  • Liquid Biopsy and Clinical Diagnostics
  • Integration of dPCR into NGS Workflow
  • Custom Assay Development
Chapter 11 Patent Analysis
  • Patent
  • PubMed
Chapter 12 Competitive Intelligence
  • Overview
  • Leading Players
  • Mergers and Acquisitions
  • Product Launches
  • Supplier Collaborations
Chapter 13 Company Profiles
  • BIO-RAD LABORATORIES INC.
  • DANAHER
  • EUROFINS SCIENTIFIC
  • JN MEDSYS
  • MERCK KGAA
  • QIAGEN
  • ROCHE (F. HOFFMANN-LA ROCHE LTD.)
  • STILLA TECHNOLOGIES
  • STANDARD BIOTOOLS INC.
  • SYSMEX INOSTICS INC.
  • THERMO FISHER SCIENTIFIC INC.
Chapter 14 Appendix: Acronyms
List of Tables
Summary Table: Global Market for dPCR, by End Use, Through 2028
Table 1: Digital PCR vs. Real-Time PCR vs. Traditional PCR, at a Glance
Table 2: NIH Funding for Clinical and Precision Medicine Research, Through 2023
Table 3: Factors Impacting dPCR Market
Table 4: Droplet-based vs. Microfluidics-based dPCR
Table 5: Common dPCR Platforms
Table 6: Global Market for dPCR, by Technology, Through 2028
Table 7: Global Market for ddPCR, by Product Type, Through 2028
Table 8: Global Market for Microfluidics-based dPCR, by Product Type, Through 2028
Table 9: Global Market for dPCR, by Product Type, Through 2028
Table 10: Global Market for dPCR Equipment, by Technology, Through 2028
Table 11: Global Market for dPCR Reagents, Consumables and Accessories, by Technology, Through 2028
Table 12: Global Market for dPCR, by End Use, Through 2028
Table 13: Global Market for dPCR in Basic Research, by Product Type, Through 2028
Table 14: Global Market for dPCR in Clinical Research, by Product Type, Through 2028
Table 15: Recent Developments in dPCR Clinical Diagnostics Market, 2019-2022
Table 16: Global Market for dPCR in Clinical Diagnostics, by Product Type, Through 2028
Table 17: Global Market for dPCR in Applied Markets, by Product Type, Through 2028
Table 18: Global Market for dPCR, by Region, Through 2028
Table 19: North American Market for dPCR, by Product Type, Through 2028
Table 20: European Market for dPCR, by Product Type, Through 2028
Table 21: Asia-Pacific Market for dPCR, by Product Type, Through 2028
Table 22: RoW Market for dPCR, by Product Type, Through 2028
Table 23: Key Environmental Issues in dPCR Industry
Table 24: Key Social and Governance Issues in dPCR Industry
Table 25: Net-Zero GHG Commitments, by Major dPCR Companies
Table 26: ESG Rankings for Major dPCR Companies, 2023*
Table 27: CDP Scope Card for Major dPCR Companies, 2022
Table 28: U.S. Patents on Digital PCR
Table 29: Leading Players in Global dPCR Market, 2022
Table 30: Selected M&A in the dPCR Industry, Jan. 2020 to July 2023
Table 31: Selected Launches of Reagents, Consumables and Accessories in the dPCR Industry, Jan. 2021 to July 2023
Table 32: Selected Launches of dPCR Instruments, Jan. 2021 to July 2023
Table 33: Selected Suppliers Collaboration in dPCR Industry, Jan. 2021 to July 2023
Table 34: Bio-Rad Laboratories Inc.: Financials, 2022
Table 35: Bio-Rad Laboratories Inc.: dPCR Product Portfolio
Table 36: Bio-Rad Laboratories Inc.: Selected Key Developments, April 2020 to July 2023
Table 37: Danaher: Financials, 2022
Table 38: IDT: dPCR Product Portfolio
Table 39: Danaher: News/Key Developments, Jan 2021 to May 2023
Table 40: Eurofins Scientific: Financials, 2022
Table 41: Eurofins Scientific: dPCR Product Portfolio
Table 42: Eurofins Scientific: News/Key Developments, Jan 2021 to May 2023
Table 43: JN Medsys: dPCR Portfolio
Table 44: Merck: Financials, 2022
Table 45: Merck: dPCR Product/Service PortfolioMerck: dPCR Product/Service Portfolio
Table 46: Merck: News/Key Developments, Jan 2021 to May 2023
Table 47: Qiagen: Financials, 2022
Table 48: Qiagen: dPCR Product Portfolio
Table 49: Qiagen: News/Key Developments, Jan 2021 to May 2023
Table 50: Roche: Financials, 2022
Table 51: Roche: dPCR Product Portfolio
Table 52: Roche: News/Key Developments, Jan 2020 to May 2023
Table 53: Stilla Technologies: dPCR Product Portfolio
Table 54: Stilla Technologies: News/Key Developments, Jan. 2021 to May 2023
Table 55: Standard BioTools Inc.: Financials, 2022
Table 56: Standard BioTools Inc.: dPCR Product Portfolio
Table 57: Sysmex Inostics Inc.: Selected Key Developments, April 2020 to July 2023
Table 58: Thermo Fisher Scientific Inc.: Segment Information
Table 59: Thermo Fisher Scientific Inc.: Financials, 2022
Table 60: Thermo Fisher Scientific Inc.: dPCR Portfolio
Table 61: Thermo Fisher Scientific Inc.: News/Key Developments, Jan. 2021 to July 2023
Table 62: Major Acronyms Used in This Report

List of Figures
Summary Figure A: Global Market for dPCR, by End Use, 2020-2028
Summary Figure B: Global Market Shares of dPCR, by End Use, 2022
Figure 1: dPCR Workflow
Figure 2: dPCR Workflow
Figure 3: Advantages of Different PCR Methods
Figure 4: Top Applications of dPCR
Figure 5: Digital PCR Breakthroughs
Figure 6: Advantages and Disadvantages of Droplet Digital PCR (ddPCR)
Figure 7: Global Market for dPCR, by Technology, 2020-2028
Figure 8: Global Market Shares of dPCR, by Technology, 2022
Figure 9: Global Market for ddPCR, by Product Type, 2020-2028
Figure 10: Global Market Shares of ddPCR, by Product Type, 2022
Figure 11: Global Market for Microfluidics-based dPCR, by Product Type, 2020-2028
Figure 12: Global Market Shares of Microfluidics-based dPCR, by Product Type, 2022
Figure 13: Global Market for dPCR, by Product Type, 2020-2028
Figure 14: Global Market Shares of dPCR, by Product Type, 2022
Figure 15: Global Market for dPCR Equipment, by Technology, 2020-2028
Figure 16: Global Market Shares of dPCR Equipment, by Technology, 2022
Figure 17: Global Market for dPCR Reagents, Consumables and Accessories, by Technology, 2020-2028
Figure 18: Global Market Shares of dPCR Reagents, Consumables and Accessories, by Technology, 2022
Figure 19: Global Pharmaceutical R&D Spending, by Geography, 2010-2019
Figure 20: Global Market for dPCR, by End Use, 2020-2028
Figure 21: Global Market Shares of dPCR, by End Use, 2022
Figure 22: Global Market for dPCR in Basic Research, by Product Type, 2020-2028
Figure 23: Global Market for dPCR in Clinical Research, by Product Type, 2020 to 2028
Figure 24: Global Market for dPCR in Clinical Diagnostics, by Product Type, 2020-2028
Figure 25: Global Market for dPCR in Applied Markets, by Product Type, 2020-2028
Figure 26: Global Market for dPCR, by Region, 2020-2028
Figure 27: Global Market Shares of dPCR, by Region, 2022
Figure 28: North American Market for dPCR, by Product Type, 2020-2028
Figure 29: Investment on Grants for Biomedical Research, by Region, in 2020
Figure 30: European Market for dPCR, by Product Type, 2020-2028
Figure 31: China: Pharmaceutical Deals, by Sector, 2018-2022
Figure 32: Asia-Pacific Market for dPCR, by Product Type, 2020-2028
Figure 33: RoW Market for dPCR, by Product Type, 2020-2028
Figure 34: Benefits of a Strong ESG Proposition
Figure 35: ESG-Adoption Level Across All Industries, Global, 2021 and 2022
Figure 36: Research Communities’ Key Sustainable Practices in Research Laboratories
Figure 37: Emerging Trends/Technologies in the dPCR Market
Figure 38: Top Automation Benefits
Figure 39: Share of U.S. Patents on Digital PCR, by Assignee's Country, 2020-August, 2023
Figure 40: Number of PubMed Publications of Articles on Real-Time PCR vs. Digital PCR, 2010-2022
Figure 41: Number of PubMed Publications of Articles on Real-Time PCR vs. Digital PCR and Linear Digital PCR, 2010-2022
Figure 42: Principle Competitive Factors in the Market for dPCR
Figure 43: Distribution Share of Strategies Used in the dCPR Industry, Jan. 2021 to July 2023
Figure 44: Bio-Rad Laboratories Inc.: Financials, 2021 and 2022
Figure 45: Bio-Rad Laboratories Inc.: Market Share, by Business Segment, 2022
Figure 46: Bio-Rad Laboratories Inc.: Revenue Share, by Region, 2022
Figure 47: Danaher: Financials, 2021 and 2022
Figure 48: Danaher: Market Share, by Business Segment, 2022
Figure 49: Danaher: Revenue Share, by Region, 2022
Figure 50: Eurofins Scientific: Financials, 2021 and 2022
Figure 51: Eurofins Scientific: Market Share, by Major Service Line, 2022
Figure 52: Eurofins Scientific: Revenue Share, by Region, 2022
Figure 53: Merck: Financial, 2021 and 2022
Figure 54: Merck: Market Share, by Business Segment, 2022
Figure 55: Merck: Revenue Share, by Region, 2022
Figure 56: Qiagen: Financials, 2021 and 2022
Figure 57: Qiagen: Revenue Share, by Region, 2022
Figure 58: Qiagen: Revenue Share, by Region, 2022
Figure 59: Roche: Financials, 2021 and 2022
Figure 60: Roche: Market Share, by Business Segment, 2022
Figure 61: Standard BioTools Inc.: Financials, 2021 and 2022
Figure 62: Standard BioTools Inc.: Market Share, by Product Type, 2022
Figure 63: Standard BioTools Inc.: Revenue Share, by Region, 2022
Figure 64: Thermo Fisher Scientific Inc.: Financials, 2021 and 2022
Figure 65: Thermo Fisher Scientific Inc.: Market Share, by Business Segment, 2022
Figure 66: Thermo Fisher Scientific Inc.: Revenue Share, by Region, 2022

Executive Summary

Digital PCR (dPCR) is the fastest-growing PCR technology. Although the underlying reaction chemistry shares many similarities with real-time PCR (qPCR), dPCR offers distinct advantages and complexities. Prized for the highly precise standard curve-free absolute quantification, dPCR is fast becoming a mainstream technique in all laboratories, from academia to biotech and pharma to the clinical diagnostic industry.

The entry of well-established PCR vendors Roche (August 2022) and Qiagen (September 2020) into the dPCR space underscores the dynamic nature and potential of the dPCR market. The participation of these industry leaders is poised to intensify investment in refining the dPCR science for use in molecular testing applications such as detecting pathogens and mutations that lead to diseases. Also, the increasing investment and focus on dPCR technology will boost customer engagement and interest. In the coming years, dPCR technology is set to expand considerably into clinical research and molecular diagnostics.

The global dPCR technology market reached $677.6 million in 2022. This market is expected to reach $1.3 million through 2028, growing at a CAGR of 11.0% from 2023 through 2028. dPCR technology should grow significantly during the forecast period due to increased genomic research efforts by academic researchers and pharmaceutical and biotechnology companies, new product technologies and innovations and the growing use of dPCR assays for clinical diagnostics, drug discovery and development applications. New product launches are expected to expand applications considerably.

Clinical diagnostics should grow the fastest among the dPCR end-use segments, reaching $376.7 million through 2028. Key growth factors in this market include the development of new diagnostic assay and sample-preparation technologies to complement dPCR. The end-use segment applied markets should register strong growth over the forecast period due to the recent development and launch of dPCR assays for the agriculture, food and environmental markets, which should grow as well during the forecast period.

Companies Mentioned

  • BIO-RAD LABORATORIES INC.
  • DANAHER
  • EUROFINS SCIENTIFIC
  • JN MEDSYS
  • MERCK KGAA
  • QIAGEN
  • ROCHE (F. HOFFMANN-LA ROCHE LTD.)
  • STILLA TECHNOLOGIES
  • STANDARD BIOTOOLS INC.
  • SYSMEX INOSTICS INC.
  • THERMO FISHER SCIENTIFIC INC.

Table Information