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Idiopathic Pulmonary Fibrosis (IPF) - Market Insights, Epidemiology and Market Forecast - 2030

  • ID: 4564655
  • Drug Pipelines
  • February 2020
  • Region: Global
  • 212 pages
  • DelveInsight
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FEATURED COMPANIES

  • Biogen Inc.
  • FibroGen
  • Galecto Biotech
  • MediciNova
  • Nitto Denko Corporation
  • Promedior Inc.
  • MORE
‘Idiopathic Pulmonary Fibrosis (IPF) - Market Insights, Epidemiology and Market Forecast-2030 report delivers an in-depth understanding of the disease, historical & forecasted epidemiology as well as the market trends of IPFs in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom) and Japan.

The Report provides the current treatment practices, emerging drugs, market share of the individual therapies, current and forecasted market size of Idiopathic Pulmonary Fibrosis (IPF) from 2017 to 2030 segmented by seven major markets. The Report also covers current treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assess underlying potential of the market.

Geography Covered
  • The United States
  • EU5 (Germany, France, Italy, Spain and the United Kingdom)
  • Japan
Study Period: 2017-2030

Idiopathic Pulmonary Fibrosis (IPF) - Disease Understanding and Treatment Algorithm

Idiopathic Pulmonary Fibrosis (IPF) is a rare, chronic, progressive fibrosing interstitial pneumonia which is found to affect the middle-aged and older adults; and affects lung tissue (alveoli in particular) by either thickening, stiffening, or persistent and progressive scarring (fibrosis) which increases irreversibly over time. If an individual has IPF, scarring affects the air sacs, limiting the amount of oxygen that gets into the blood. With less oxygen in the blood, one can get breathlessness from everyday activities, like walking. This group of lung disorders is also known as ‘Diffuse Parenchymal Lung Diseases,' which is characterized by a broader umbrella of ‘Interstitial Lung Diseases (IDLs).

The Idiopathic Pulmonary Fibrosis (IPF) market report gives the thorough understanding of the Idiopathic Pulmonary Fibrosis by including details such as disease definition, classification, symptoms, etiology, pathophysiology, diagnostic trends. It also provides treatment algorithms and treatment guidelines for Idiopathic Pulmonary Fibrosis in the US, Europe and Japan.

Idiopathic Pulmonary Fibrosis Epidemiology

The Idiopathic Pulmonary Fibrosis (IPF) epidemiology division provide the insights about historical and current patient pool and forecasted trend for every seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the report also provides the diagnosed patient pool and their trends along with assumptions undertaken.

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology (Prevalent cases of IPF, Age-specific cases, Prevalence by severity and Gender-specific cases of IPF) scenario of Idiopathic Pulmonary Fibrosis (IPF) in the 7MM covering United States, EU5 countries (Germany, Spain, Italy, France and United Kingdom) and Japan from 2017-2030.

According to the publisher, the total number of prevalent cases of Idiopathic Pulmonary Fibrosis (IPF) in 7 MM was found to be 229,170, in the year 2017.

Idiopathic Pulmonary Fibrosis Drug Chapters

This segment of the Idiopathic Pulmonary Fibrosis report encloses the detailed analysis of marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.

Currently, there are two approved drugs in the market; Esbriet (Pirfenidone) and Ofev (Nintedanib) aims at slowing down the disease progression through acting like anti-fibrotic mediators. Nintedanib is a potent intracellular inhibitor of the receptor tyrosine kinases PDGFR, FGFR, vascular endothelial growth factor receptor (VEGFR) and non-receptor tyrosine kinases of the Src family; Pirfenidone, on the other, is responsible for reducing markers of oxidative stress, reducing the proliferation of lung fibroblasts and their differentiation into myofibroblasts by attenuating key TGF-ß-induced signalling pathways (i.e., Smad3, p38, and Akt), reducing the expression of TGF-ß-induced heat-shock protein 47 (HSP47), which is involved in processing/secretion of procollagen, and reducing expression of a smooth muscle actin (a-SMA) and collagen type 1.

Idiopathic Pulmonary Fibrosis Market Outlook

The Idiopathic Pulmonary Fibrosis market outlook of the report helps to build the detailed comprehension of the historic, current and forecasted trend of the market by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.

This segment gives a through detail of market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criteria's, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

According to the publisher, the market of Idiopathic Pulmonary Fibrosis in 7MM was found to be USD 1,510.4 Million in 2017, and is expected to increase during the course of the study period (2017-2030). Among the 7MM, the United States accounts for the largest market size of IPF, in comparison to EU5 (the United Kingdom, Germany, Italy, France, and Spain) and Japan.

Idiopathic Pulmonary Fibrosis Drugs Uptake

This section focusses on the rate of uptake of the potential drugs recently launched in the market or will get launched in the market during the study period from 2017-2030. The analysis covers market uptake by drugs; patient uptake by therapies and sales of each drug.

This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Idiopathic Pulmonary Fibrosis Report Insights
  • Patient Population
  • Therapeutic Approaches
  • Pipeline Analysis
  • Market Size and Trends
  • Market Opportunities
  • Impact of upcoming Therapies
Idiopathic Pulmonary Fibrosis Report Key Strengths
  • 11 Year Forecast
  • 7MM Coverage
  • Epidemiology Segmentation
  • Drugs Uptake
  • Highly Analyzed Market
  • Key Cross Competition
Idiopathic Pulmonary Fibrosis Report Assessment
  • Current Treatment Practices
  • Unmet Needs
  • Detailed Pipeline Product Profiles
  • Market Attractiveness
  • Market Drivers and Barriers
Key Benefits
  • This report will help to develop Business Strategies by understanding the trends shaping and driving Idiopathic Pulmonary Fibrosis market
  • Organize sales and marketing efforts by identifying the best opportunities for Idiopathic Pulmonary Fibrosis market
  • To understand the future market competition in the Idiopathic Pulmonary Fibrosis market.
Note: Product cover images may vary from those shown
2 of 3

FEATURED COMPANIES

  • Biogen Inc.
  • FibroGen
  • Galecto Biotech
  • MediciNova
  • Nitto Denko Corporation
  • Promedior Inc.
  • MORE
1. Key Insights

2. Idiopathic Pulmonary Fibrosis Market Overview at a Glance
2.1. Market Share (%) Distribution of Idiopathic Pulmonary Fibrosis in 2017
2.2. Market Share (%) Distribution of Idiopathic Pulmonary Fibrosis in 2028

3. Disease Background and Overview: Idiopathic Pulmonary Fibrosis (IPF)
3.1. Introduction
3.2. Statistics about Idiopathic Pulmonary Fibrosis
3.3. Staging of Idiopathic Pulmonary Fibrosis
3.4. Risk Factors and Disease Causes
3.5. Symptoms
3.6. Pathogenesis
3.7. Diagnosis

4. Epidemiology and Patient Population
4.1. Key Findings
4.2. 7MM Prevalent Population of Idiopathic Pulmonary Fibrosis

5. Country Wise-Epidemiology of Idiopathic Pulmonary Fibrosis
5.1. United States
5.1.1. Prevalent cases of Idiopathic Pulmonary Fibrosis in the United States
5.1.2. Prevalent Population of Idiopathic Pulmonary Fibrosis by severity
5.1.3. Gender-specific Idiopathic Pulmonary Fibrosis Prevalence
5.1.4. Age-specific Idiopathic Pulmonary Fibrosis Prevalence
5.2. EU5
5.2.1. Prevalent Population of Idiopathic Pulmonary Fibrosis in EU5
5.2.2. Germany
5.2.2.1. Prevalent Population of Idiopathic Pulmonary Fibrosis
5.2.2.2. Prevalent Population of Idiopathic Pulmonary Fibrosis by severity
5.2.2.3. Gender-specific Idiopathic Pulmonary Fibrosis Prevalence
5.2.2.4. Age-specific Idiopathic Pulmonary Fibrosis Prevalence
5.2.3. France
5.2.3.1. Prevalent Population of Idiopathic Pulmonary Fibrosis
5.2.3.2. Prevalent Population of Idiopathic Pulmonary Fibrosis by severity
5.2.3.3. Gender-specific Idiopathic Pulmonary Fibrosis Prevalence
5.2.3.4. Age-specific Idiopathic Pulmonary Fibrosis Prevalence
5.2.4. Italy
5.2.4.1. Prevalent Population of Idiopathic Pulmonary Fibrosis
5.2.4.2. Prevalent Population of Idiopathic Pulmonary Fibrosis by severity
5.2.4.3. Gender-specific Idiopathic Pulmonary Fibrosis Prevalence
5.2.4.4. Age-specific Idiopathic Pulmonary Fibrosis Prevalence
5.2.5. United Kingdom
5.2.5.1. Prevalent Population of Idiopathic Pulmonary Fibrosis
5.2.5.2. Prevalent Population of Idiopathic Pulmonary Fibrosis by severity
5.2.5.3. Gender-specific Idiopathic Pulmonary Fibrosis Prevalence
5.2.5.4. Age-specific Idiopathic Pulmonary Fibrosis Prevalence
5.2.6. Spain
5.2.6.1. Prevalent Population of Idiopathic Pulmonary Fibrosis
5.2.6.2. Prevalent Population of Idiopathic Pulmonary Fibrosis by severity
5.2.6.3. Gender-specific Idiopathic Pulmonary Fibrosis Prevalence
5.2.6.4. Age-specific Idiopathic Pulmonary Fibrosis Prevalence
5.3. Japan
5.3.1. Prevalent Population of Idiopathic Pulmonary Fibrosis
5.3.2. Prevalent Population of Idiopathic Pulmonary Fibrosis by severity
5.3.3. Gender-specific Idiopathic Pulmonary Fibrosis Prevalence
5.3.4. Age-specific Idiopathic Pulmonary Fibrosis Prevalence

6. Current Treatment Practices
6.1. ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmonary Fibrosis (An Update of 2011 Clinical Practice Guideline)
6.2. Patient Journey

7. Unmet Needs

8. Organizations contributing toward IPF

9. KOL’s Views: Idiopathic Pulmonary Fibrosis

10. Case Reports
10.1. Idiopathic Pulmonary Fibrosis: As case Discussion in the US
10.2. Occurrence of idiopathic pulmonary fibrosis during immunosuppressive treatment: a case report of Europe
10.3. Nintedanib prevented fibrosis progression and lung cancer growth in idiopathic pulmonary fibrosis - A Japanese Case Report

11. Marketed Products
11.1. Esbriet (Pirfenidone): InterMune Inc.
11.1.1. Product Description
11.1.2. Regulatory Milestones
11.1.3. Advantages & Disadvantages
11.1.4. Safety and Efficacy of Esbriet
11.1.5. Side effects of Esbriet
11.1.6. Product Profile
11.2. Ofev (Nintedanib): Boehringer Ingelheim Pharma GmbH & Co. KG
11.2.1. Product Description
11.2.2. Regulatory Milestones
11.2.3. Advantages and Disadvantages
11.2.4. Safety and Efficacy of Ofev
11.2.5. Side effects of Ofev
11.2.6. Product Profile

12. Emerging Therapies
12.1. Key Cross Competition
12.2. Tipelukast: MediciNova
12.2.1. Drug Description
12.2.2. Clinical Development
12.2.3. Clinical Trials Information
12.2.4. Safety and Efficacy
12.2.5. Product Profile
12.3. Pamrevlumab: FibroGen
12.3.1. Drug Description
12.3.2. Regulatory Milestones
12.3.3. Other Development Activities
12.3.4. Clinical Development
12.3.5. Clinical Trials Information
12.3.6. Safety and Efficacy
12.3.7. Product Profile
12.4. KD025: Kadmon Corporation, LLCs
12.4.1. Drug Description
12.4.2. Other Development Activities
12.4.3. Clinical Development
12.4.4. Clinical Trials Information
12.4.5. Safety and Efficacy
12.4.6. Product Profile
12.5. PRM 151: Promedior, Inc.
12.5.1. Drug Description
12.5.2. Regulatory Milestones
12.5.3. Other Development Activities
12.5.4. Clinical Development
12.5.5. Clinical Trials Information
12.5.6. Safety and Efficacy
12.5.7. Product Profile
12.6. GLPG1690: Galapagos NV
12.6.1. Drug Description
12.6.2. Regulatory Milestones
12.6.3. Other Development Activities
12.6.4. Clinical Development
12.6.5. Clinical Trials Information
12.6.6. Safety and Efficacy
12.6.7. Product Profile

13. Other Promising Candidates
13.1. CC-90001: Celgene Corporation
13.1.1. Drug Description
13.1.2. Clinical Development
13.1.3. Clinical Trials Information
13.1.4. Safety and Efficacy
13.1.5. Product Profile
13.2. LT-1001: Beijing Tide Pharmaceutical
13.2.1. Drug Description
13.2.2. Other Development Activities
13.2.3. Clinical Development
13.2.4. Clinical Trials Information
13.2.5. Safety and Efficacy
13.2.6. Product Profile
13.3. LT-1002: Chong Kun Dang Pharmaceutical
13.3.1. Drug Description
13.3.2. Other Development Activities
13.3.3. Clinical Development
13.3.4. Clinical Trials Information
13.3.5. Product Profile
13.4. BG00011: Biogen Inc.
13.4.1. Drug Description
13.4.2. Regulatory Milestones
13.4.3. Other Development Activities
13.4.4. Clinical Development
13.4.5. Clinical Trials Information
13.4.6. Safety and Efficacy
13.4.7. Product Profile
13.5. PBI4050: ProMetic Life Sciences
13.5.1. Drug Description
13.5.2. Regulatory Milestones
13.5.3. Other Development Activities
13.5.4. Clinical Development
13.5.5. Clinical Trials Information
13.5.6. Safety and Efficacy
13.5.7. Product Profile
13.6. TD139: Galecto Biotech
13.6.1. Drug Description
13.6.2. Other Development Activities
13.6.3. Clinical Development
13.6.4. Clinical Trials Information
13.6.5. Safety and Efficacy
13.6.6. Product Profile
13.7. VAY736: Novartis
13.7.1. Drug Description
13.7.2. Other Development Activities
13.7.3. Clinical Development
13.7.4. Clinical Trials Information
13.7.5. Product Profile
13.8. TAS-115: Taiho Pharmaceutical
13.8.1. Drug Description
13.8.2. Clinical Development
13.8.3. Clinical Trials Information
13.8.4. Product Profile
13.9. ND-L02-s0201: Nitto Denko Corporation
13.9.1. Drug Description
13.9.2. Other Development Activities
13.9.3. Clinical Development
13.9.4. Clinical Trials Information
13.9.5. Safety and Efficacy
13.9.6. Product Profile
13.10. Nalbuphine ER: Trevi Therapeutics
13.10.1. Drug Description
13.10.2. Clinical Development
13.10.3. Clinical Trials Information
13.10.4. Product Profile
13.11. RVT-1601: Respivant Sciences
13.11.1. Drug Description
13.11.2. Clinical Development
13.11.3. Clinical Trials Information
13.11.4. Safety and Efficacy
13.11.5. Product Profile
13.12. Gefapixant: Merck & Co.
13.12.1. Drug Description
13.12.2. Other Development Activities
13.12.3. Clinical Development
13.12.4. Clinical Trials Information
13.12.5. Safety and Efficacy
13.12.6. Product Profile

14. Idiopathic Pulmonary Fibrosis: Market Analysis
14.1. Key Findings
14.2. Total Market Size of Idiopathic Pulmonary Fibrosis in 7MM
14.3. Therapy Based Market Size of Idiopathic Pulmonary Fibrosis in 7MM

15. Market Size of Idiopathic Pulmonary Fibrosis by Country
15.1. United States Market Analysis
15.1.1. Market Size of Idiopathic Pulmonary Fibrosis in the US
15.1.2. Therapy Based Market Size of Idiopathic Pulmonary Fibrosis in the US
15.2. EU5 Market Outlook
15.2.1. Germany
15.2.1.1. Market Size of Idiopathic Pulmonary Fibrosis in Germany
15.2.1.2. Therapy Based Market Size of Idiopathic Pulmonary Fibrosis in Germany
15.2.2. France
15.2.2.1. Market Size of Idiopathic Pulmonary Fibrosis in France
15.2.2.2. Therapy Based Market Size of Idiopathic Pulmonary Fibrosis in France
15.2.3. Italy
15.2.3.1. Market Size of Idiopathic Pulmonary Fibrosis in Italy
15.2.3.2. Therapy Based Market Size of Idiopathic Pulmonary Fibrosis in Italy
15.2.4. United Kingdom
15.2.4.1. Market Size of Idiopathic Pulmonary Fibrosis in the UK
15.2.4.2. Therapy Based Market Size of Idiopathic Pulmonary Fibrosis in the UK
15.2.5. Spain
15.2.5.1. Market Size of Idiopathic Pulmonary Fibrosis in Spain
15.2.5.2. Therapy Based Market Size of Idiopathic Pulmonary Fibrosis in Spain
15.3. Japan: Market Analysis
15.3.1. Market Size of Idiopathic Pulmonary Fibrosis in Japan
15.3.2. Therapy Based Market Size of Idiopathic Pulmonary Fibrosis in Japan

16. Market Drivers of Idiopathic Pulmonary Fibrosis

17. Market Barriers of Idiopathic Pulmonary Fibrosis

18. Appendix
18.1. Report Methodology

19. Publisher Capabilities

20. Disclaimer

21. About the Publisher
Note: Product cover images may vary from those shown
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  • FibroGen
  • Kadmon Corporation LLC
  • Promedior Inc.
  • Galapagos NV
  • MediciNova
  • Ashai Kasei Pharma Corporation
  • Celgene Corporation
  • Beijing Tide Pharmaceutical
  • Chong Kun Dang Pharmaceutical
  • Biogen Inc.
  • ProMetic Life sciences
  • Galecto Biotech
  • Novartis
  • Taiho Pharmaceutical
  • Nitto Denko Corporation
  • Trevi Therapeutics
  • Respivant Sciences
  • Merck & Co
Note: Product cover images may vary from those shown
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