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Human Microbiome: The Unavoidable Companion “Technological Report and Market Scenario”

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  • 176 Pages
  • May 2018
  • Region: Global
  • Ingenious e-Brain Solutions
  • ID: 4599620
The Human body is made up of over 100 trillion of microbes which have outnumbered human cells ten to one. The human body is an ecosystem i.e. home to trillions of microbes like bacteria, fungi, virus, etc. and the community of the microbes that resides in it is known as the human microbiome. The human microbiome is an aggregation of the microbes that reside on or within the body fluids or tissues. These communities play an important role in human physiology, immune system development, digestion, and detoxification reactions.

This report provides an in-depth diverse perspective and the importance of human microbiome in health and disease-related conditions. Alterations in human microbiome occur by exposure to various extrinsic factors like diet, xenobiotics, drugs as well as pathogens which contribute to the pathogenesis of various metabolic, neurological, immunological, and cancer-promoting diseases . It will also disclose the key aspects of the human microbiome as well as the current biotechnological tools and techniques for studying the human microbiome.

Various human microbial studies are known to identify and categorize the bacterial taxa and functions that are shared by a majority of individuals. This report will cover the factors which can affect the human microbiome as well as various studies which are well known and can be used as a tool for identifying the potential of the functional microbiome. It will also emphasize on the various microbiome-based markers which can be useful in determining the disease or the risk of disease and various approaches like Fecal Microbiota Transplant (FMT), Genetically engineered probiotics, etc. which have a profound effect in improving the microbiome condition.

According to the reported data, the global human microbiome market is nearly expected to grow by $521.23 million in 2022. This report covers its market trends analysis and its growth in the commercial market. It will also include the major key players like Agilent technologies, Abbott, Biocartis, etc. which are actively working in this field and will also be discussed its future market scenario.

This report will also focus on global market competitive analysis as well as the Major competitors/players in this market which are actively working on the human microbiome. It will also discuss the agreements, partnerships, collaborations/ Joint Ventures, acquisitions/mergers, new products launch, other key strategies in this field.

Table of Contents

1 Table of Contents
1.1 List of Tables
1.2 List of Figures
2 Executive Summary3 Introduction
4 Human Microbiome: Overview
4.1 Primitive Companion
4.1.1 Microbiome Diversity
4.1.2 Microbiome Commensal or Symbiosis
4.1.3 Microbiome as a Human Organ
4.2. The Common Core Microbiome in Human Large Intestine
4.2.1 Phylogenetic Core
4.2.2 Minimal Intestinal Metagenome
4.3 Host Biology and Dysbiosis
4.4 The Role of The Microbiome in Human Health and Disease
4.4.1 The Microbiome and Human Health
4.4.2 The Pediatric Microbiome
4.4.3 Innate Immune Response
4.4.4 Role of Microbiome in Diseases
4.5 Microbiome as a Multipurpose Biomarker
4.6 Microbiome Cross-Talk
4.6.1 Microbiome-Microbiome Cross Talk
4.6.2 Host-Microbiome Cross Talk
4.7 The Human Microbiome Projects
4.8 Current Methods for Studying the Human Microbiome
4.9 Microbiome: Timeline
4.10 Latest Research and Reviews
5 Research Scope6 Research Methodology7 Research Approach8 Research Sources
9 Technical Analysis
9.1 Human Microbiome in IVD And Other Healthcare Applications
9.1.1 Microbiome - Bacteria in Disease Processes
9.1.2 Growing Interest in the Microbiome
9.1.3 Metagenomics
9.1.4 Metabolomic Profiling
9.1.5 Microbiome Diagnostics
9.1.6 Selected Molecular Microbiome-Based Tests
9.1.7 Diagnostic Biomarkers
9.1.8 Precision or Personalized Medicine Approaches
9.1.9 Fecal Microbiome Transplantation (FMT)
9.1.10 Other Selected Microbiome-Related Therapeutic Approaches
9.1.11 Microbiome Modulators
9.2 Human Microbiome in Disease
9.2.1 Human Microbiome and Infectious Diseases Clostridium Difficile Infection Helicobacter Pylori Infection Bacterial Vaginosis HIV Infection Fungal Infection
9.2.2 Human Microbiome and Liver Diseases
9.2.3 Human Microbiota Associated with Gastrointestinal Malignancy Gastric Cancer Colorectal Cancer Esophageal Cancer
9.2.4 Human Microbiome and Metabolic Disorders Obesity Type 2 Diabetes
9.2.5 Human Microbiome and Autoimmune Disorder Celiac Disease Rheumatoid Arthritis Ankylosing Spondylitis Psoriatic Arthritis Systemic Lupus Erythematosus Sjogren’s Syndrome Vasculitis
9.2.6 Human Microbiome and Other Diseases Allergic Diseases Psychiatric Diseases Atherosclerosis Paneth Cell Dysfunction Cerebrovascular Disease Multiple Sclerosis
9.3 Advancements in Human Microbiome Technology
9.4 Ingredients Effecting Human Microbiome
9.4.1 Proteins
9.4.2 Lipids
9.4.3 Carbohydrates
9.4.4 Glutens
9.4.5 Polyphenols
9.4.6 Green Vegetables
9.4.7 Fruits
9.4.8 Dairy products
9.4.9 Meat
9.4.10 Junk Foods
9.4.11 Fermented Foods
9.4.12 Processed Foods
9.4.13 Antibiotics
9.4.14 Probiotics
9.4.15 Prebiotics
9.4.16 Other Active agents
10 Mode of Administration of Microbiome Products11 Microbiome Product forms
12 Market Analysis
12.1 Market Overview
12.2 Human Microbiome Market Segmentation
12.2.1 Based on Application Therapeutic Diagnostic
12.2.2 Based on Disease Type
12.2.3 Based on Product Type Prebiotics Foods Drugs Diagnostic Devices Nutritionally Incomplete Formulae Formulae for Metabolic Disorders Nutritionally Complete Formulae Oral Rehydration Products Other Probiotics Supplements
12.2.4 Based on Distribution Channel
12.2.5 Based on End Users
12.2.6 Based on Geography North America & South America Europe Asia-Pacific Middle East & Africa
12.3 Global Human Microbiome Market Competitive Analysis
12.4 Human Microbiome Market Major Market Competitors/Players
13 Market Trend Analysis
13.1 Drivers
13.2 Restraints
13.3 Opportunities
13.4 Threats
13.5 Application Analysis
13.6 Product Analysis
13.7 Research Scenario
13.8 Emerging Markets
13.9 Supply Chain Analysis
13.10 Futuristic Market Scenario
13.11 Burning Issues
14 Key Microbiome Players (Company Profiling)
14.1 4D Pharma plc
14.2 Abbott Diagnostics
14.3 Agilent Technologies Inc.
14.4 Anaeropharma Science
14.5 AOBiome, LLC
14.6 Aperiomics, Inc.
14.7 Atlas Biomed
14.8 AvidBiotics
14.9 Beckman Coulter / Danaher
14.10 Becton, Dickinson and Company (BD)
14.11 Biocartis Group
14.12 C3J Therapeutics (formerly C3 Jian)
14.13 Crestovo (Finch Therapeutics Group)
14.14 Danaher Corporation
14.15 Eppendorf AG
14.16 Evelo Biosciences
14.17 Evolve Biosystems
14.18 Finch Therapeutics Group
14.19 One Codex
14.20 OpenBiome
14.21 Optibiotix
14.22 OraSure Technologies, Inc.
14.23 Osel, Inc.
14.24 PerkinElmer, Inc. (Pe)
14.25 Pfizer, Inc.
14.26 Phase Genomics
14.27 Proderm IQ
14.28 Prodigest
14.29 Promega Corporation
14.30 PureFlora Inc.
14.31 QIAGEN
14.32 Quay Pharma
14.33 Whole Biome
14.34 Xycrobe Therapeutics, Inc.
14.35 Zymo Research
15 Key Microbiome Developments
15.1 Agreements, Partnerships, Collaborations and Joint Ventures
15.2 Acquisitions & Mergers
15.3 New Product Launch
15.4 Expansions
15.5 Other Key Strategies
List of Tables
Table 1 Focus Disease Areas for Microbiome Research
Table 2 Microbiome Drug Development Approaches
Table 3 Venture Capital Investments in Microbiome Start-Ups ($ Millions
Table 4 Industry collaborations in Microbiome-based Companies ($ Millions)
Table 5 4D Pharma Pipeline
Table 6 Avidbiotics Pipeline
Table 7 Osel Pipeline
Table 8 Bioinformatic tools for metagenomic datasets analyses
Table 9 Microbiome-based Drugs in Development for Cancer
Table 10 Microbiota Associated with Type 2 Diabetes
Table 11 Microbiome-based Drugs in Development for Clostridium Difficile Infection
Table 12 Globally Patient Volumes for Microbiome-based Drugs for Type 2 Diabetes, by Company, through 2024 TABLE 22 Table 13 Globally Market for Microbiome-based Drugs for Type 2 Diabetes, by Company, through 2024
Table 14 Global Prevalence of Clostridium Difficile Infection, through 2024
Table 15 Microbiome-based Drugs in Development for Clostridium Difficile Infection
Table 16 Globally Market Shares of Microbiome-based Drugs for Clostridium Difficile Infection, by Company, 2018–2024 (%)
Table 17 Globally Patient Volumes for Microbiome-based Drugs for Clostridium Difficile Infection, by Company, through 2024 (Thousands)
Table 18 Globally Market for Microbiome-based Drugs for Clostridium Difficile Infection, by Company, through 2024 ($ Millions
Table 19 Rest of the World Market for Microbiome-based Drugs for Clostridium Difficile Infection, by Country/Region, through 2024 ($ Millions
Table 20 Microbiome-based Drugs in Development for Skin Diseases
Table 21 Microbiome-based Drugs in Development for Recurrent Bacterial Vaginosis and Urinary Tract Infection
Table 22 Microbiota Associated with Celiac Disease
Table 23 Comparison of Microbiome Sequencing Technologies
List of Figures
Figure 1: Microbiome and human body environment
Figure 2: Human microbiome cross talk
Figure 3: Microbial Timeline
Figure 4: Human microbiome therapeutic and diagnostic applications
Figure 5: Ingredients effecting human microbiome
Figure 6: Global human microbiome market opportunity by Indication (2022)
Figure 7: Global human microbiome market (geographically)
Figure 7: Global human microbiome market (application based)
Figure 8: Global human microbiome market (product based)
Figure 9: Global human microbiome market (disease based)
Figure 10: Human Microbiome Based Drugs, Pipeline Projects
Figure 11: Human Microbiome Based Drugs, Pipeline Projects, 2016 (Number of Clinical/Preclinical Projects)
Figure 12. Gut Microbiota and Specific Commensals as Potential Preventive or Therapeutic Agents.
Figure 13. Temporal Development of the Gut Microbiota in Humans

Companies Mentioned

  • 4D Pharma plc

  • AOBiome, LLC

  • Abbott Diagnostics

  • Agilent Technologies Inc.

  • Anaeropharma Science

  • Aperiomics, Inc.

  • Atlas Biomed

  • AvidBiotics

  • Beckman Coulter / Danaher

  • Becton, Dickinson and Company (BD)

  • Biocartis Group

  • C3J Therapeutics (formerly C3 Jian)

  • Crestovo (Finch Therapeutics Group)

  • Danaher Corporation

  • Eppendorf AG

  • Evelo Biosciences

  • Evolve Biosystems

  • Finch Therapeutics Group

  • One Codex

  • OpenBiome

  • Optibiotix

  • OraSure Technologies, Inc.

  • Osel, Inc.

  • PerkinElmer, Inc. (Pe)

  • Pfizer, Inc.

  • Phase Genomics

  • Proderm IQ

  • Prodigest

  • Promega Corporation

  • PureFlora Inc.


  • Quay Pharma

  • Whole Biome

  • Xycrobe Therapeutics, Inc.

  • Zymo Research