Microbiome and Metabolome in Diagnosis, Therapy, and Other Strategic Applications is the first book to simultaneously cover the microbiome and the metabolome in relevant clinical conditions. In a pioneering fashion, it addresses not only the classic intestinal environment, but also the oral, gastric, lung, skin and vaginal microbiome that is in line with the latest investigations. Nonbacterial microbiomes, such as fungi and viruses are not overlooked, and the plasma microbiome is also discussed. As plasma, brain, placenta, tumor cells, and other sterile fluids and tissues, are increasingly recognized to potentially host a microbiome, albeit a limited one, this is a timely resource.
The book's editors were fortunate to have the input of renowned collaborators from nearly all continents. This is truly an international effort that brings the latest in the field to students and professionals alike.
- Provides comprehensive coverage on diagnosis, therapy, pharmacotherapy and disease prevention in context of the microbiome and metabolome
- Focuses on the proposed physiological or pathological conditions
- Presents an up-to-date, useful reference
Tools, toolstations and models 1. Germ free animals 2. Gnotobiotic animals in cardiovascular disease 3. Viruses and Fungi 4. Gut Metabolome 5. Metabolome tools and information retrieval 6. In-vitro model of microbiome 7. Breath analysis
Background information 8. Infancy to elderly 9. The oral microbiome 10. Gastric microbiome 11. The Human Vaginal Microbiome 12. Bioactive molecules of the microbiome 13. Intestinal barrier and mucosal defense 14. The Crosstalk Between Bile Acids and Intestinal Microbiota
Established and experimental interventions 15. Probiotics in inflammatory bowel disease 16. Fecal transplantation 17. Effects of probiotics on improvement of metabolic factors in pregnant women: a meta-analysis of randomised placebo-controlled trials 18. Fecal transplantation Clostridium difficile 19. Phage therapy 20. Antibiotics 21. The myth and therapeutic potentials of postbiotics
Diagnostic and therapeutical applications 22. Diabetes 23. Obesity 24. Bariatric surgery 25. Hypertension 26. Functional digestive diseases 27. The microbiome and metabolome in nonalcoholic fatty liver disease 28. The Microbiome and metabolome in alcoholic liver disease 29. Neonatal sepsis 30. Septic elderly 31. The lung microbiome and metabolome in the diagnosis of pulmonary disease 32. HIV infection 33. Autoimmune diseases 34. Multiple sclerosis 35. Bone health 36. Kidney diseases 37. Dysbiosis in benign and malignant diseases of the exocrine pancreas 38. Cancer 39. The Microbiome in Graft versus host disease 40. Emotions
Applications for foods, drugs, and xenobiotics 41. Vegetarians 42. Metformin antiobesity 43. Smog and the intestinal microbiome
Challenges and promises for the future 44. New generation probiotics 45. Fecal transplantation in inflammatory bowel disease 46. The future of the microbiome and metabolome
Joel Faintuch is a gastrointestinal surgeon, and former International Guest Fellow of the American College of Surgeons. He is Honorary Fellow of three Surgical Societies, and has served as Visiting Professor at the University of Maastricht. He was the pioneer of Parenteral and Enteral Nutrition in Brazil and South America, and a founding member of three medical societies. In the last years, his focus has been in the Intestinal Microbiome. Joel Faintuch is the author of over 250 articles in peer-reviewed journals, along with 10 books, three theses, and over 200 chapters in books, and other publications.
Salomao Faintuch is the Clinical Director of Vascular and Interventional Radiology at Beth Israel Deaconess Medical Center and Harvard Medical School. He has authored more than 50 articles in peer-reviewed journals, along with 5 Society Guidelines and Standards of Practice and 3 textbooks. He is a Radiological Society of North America Research Scholar, serves in eight national society committees, and is member of the Editorial Board of three international journals.